{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T23:41:50Z","timestamp":1773272510985,"version":"3.50.1"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2003,6,23]],"date-time":"2003-06-23T00:00:00Z","timestamp":1056326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2003,6,23]],"date-time":"2003-06-23T00:00:00Z","timestamp":1056326400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bone Marrow Transplant"],"published-print":{"date-parts":[[2003,7,1]]},"DOI":"10.1038\/sj.bmt.1704081","type":"journal-article","created":{"date-parts":[[2003,6,18]],"date-time":"2003-06-18T16:07:23Z","timestamp":1055952443000},"page":"1-7","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Hematopoietic stem cell gene therapy: progress toward therapeutic targets"],"prefix":"10.1038","volume":"32","author":[{"given":"J L","family":"Vollweiler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S P","family":"Zielske","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J S","family":"Reese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S L","family":"Gerson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2003,6,23]]},"reference":[{"key":"BF1704081_CR1","doi-asserted-by":"publisher","first-page":"1797","DOI":"10.1084\/jem.183.4.1797","volume":"183","author":"MA Goodell","year":"1996","unstructured":"Goodell MA, Brose K, Paradis G et al. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 1996; 183: 1797\u20131806.","journal-title":"J Exp Med"},{"key":"BF1704081_CR2","first-page":"440","volume":"26","author":"F Morel","year":"1998","unstructured":"Morel F, Galy A, Chen B et al. Equal distribution of competitive long-term repopulating stem cells in the CD34+ and CD34\u2212 fractions of Thy-1lowLin-\/lowSca-1+ bone marrow cells. Exp Hematol 1998; 26: 440\u2013448.","journal-title":"Exp Hematol"},{"key":"BF1704081_CR3","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1126\/science.273.5272.242","volume":"273","author":"M Osawa","year":"1996","unstructured":"Osawa M, Hanada K, Hamada H et al. Long-term lymphohematopoietic reconstitution by a single CD34\u2212 low\/negative hematopoietic stem cell. Science 1996; 273: 242\u2013245.","journal-title":"Science"},{"key":"BF1704081_CR4","doi-asserted-by":"crossref","first-page":"2548","DOI":"10.1182\/blood.V94.8.2548.420k38_2548_2554","volume":"94","author":"T Sato","year":"1999","unstructured":"Sato T, Laver JH, Ogawa M . Reversible expression of CD34 by murine hematopoietic stem cells. Blood 1999; 94: 2548\u20132554.","journal-title":"Blood"},{"key":"BF1704081_CR5","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1038\/sj.bmt.1702791","volume":"27","author":"ON Koc","year":"2001","unstructured":"Koc ON, Lazarus HM . Mesenchymal stem cells: heading into the clinic. Bone Marrow Transplant 2001; 27: 235\u2013239.","journal-title":"Bone Marrow Transplant"},{"key":"BF1704081_CR6","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1016\/S0301-472X(00)00482-3","volume":"28","author":"RJ Deans","year":"2000","unstructured":"Deans RJ, Moseley AB . Mesenchymal stem cells: biology and potential clinical uses. Exp Hematol 2000; 28: 875\u2013884.","journal-title":"Exp Hematol"},{"key":"BF1704081_CR7","doi-asserted-by":"publisher","first-page":"1675","DOI":"10.1016\/S0301-472X(99)00101-0","volume":"27","author":"ON Koc","year":"1999","unstructured":"Koc ON, Peters C, Aubourg P et al. Bone marrow-derived mesenchymal stem cells remain host-derived despite successful hematopoietic engraftment after allogeneic transplantation in patients with lysosomal and peroxisomal storage diseases. Exp Hematol 1999; 27: 1675\u20131681.","journal-title":"Exp Hematol"},{"key":"BF1704081_CR8","doi-asserted-by":"publisher","first-page":"1857","DOI":"10.1182\/blood.V99.5.1857","volume":"99","author":"MA Baxter","year":"2002","unstructured":"Baxter MA, Wynn RF, Deakin JA et al. Retrovirally mediated correction of bone marrow-derived mesenchymal stem cells from patients with mucopolysaccharidosis type I. Blood 2002; 99: 1857\u20131859.","journal-title":"Blood"},{"key":"BF1704081_CR9","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1111\/j.1749-6632.2001.tb03593.x","volume":"938","author":"M Reyes","year":"2001","unstructured":"Reyes M, Verfaillie CM . Characterization of multipotent adult progenitor cells a subpopulation of mesenchymal stem cells. Ann NY Acad Sci 2001; 938: 231\u2013233 discussion 233\u2013235.","journal-title":"Ann NY Acad Sci"},{"key":"BF1704081_CR10","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1172\/JCI0214327","volume":"109","author":"M Reyes","year":"2002","unstructured":"Reyes M, Dudek A, Jahagirdar B et al. Origin of endothelial progenitors in human postnatal bone marrow. J Clin Invest 2002; 109: 337\u2013346.","journal-title":"J Clin Invest"},{"key":"BF1704081_CR11","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1038\/86498","volume":"7","author":"AA Kocher","year":"2001","unstructured":"Kocher AA, Schuster MD, Szabolcs MJ et al. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med 2001; 7: 430\u2013436.","journal-title":"Nat Med"},{"key":"BF1704081_CR12","doi-asserted-by":"publisher","first-page":"2099","DOI":"10.1002\/j.1460-2075.1993.tb05858.x","volume":"12","author":"T Roe","year":"1993","unstructured":"Roe T, Reynolds TC, Yu G et al. Integration of murine leukemia virus DNA depends on mitosis. EMBO J 1993; 12: 2099\u20132108.","journal-title":"EMBO J"},{"key":"BF1704081_CR13","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1126\/science.272.5259.263","volume":"272","author":"L Naldini","year":"1996","unstructured":"Naldini L, Blomer U, Gallay P et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996; 272: 263\u2013267.","journal-title":"Science"},{"key":"BF1704081_CR14","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.1128\/jvi.70.4.2581-2585.1996","volume":"70","author":"RK Akkina","year":"1996","unstructured":"Akkina RK, Walton RM, Chen ML et al. High-efficiency gene transfer into CD34+ cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus envelope glycoprotein G. J Virol 1996; 70: 2581\u20132585.","journal-title":"J Virol"},{"key":"BF1704081_CR15","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/0092-8674(95)90306-2","volume":"82","author":"D Trono","year":"1995","unstructured":"Trono D . HIV accessory proteins: leading roles for the supporting cast. Cell 1995; 82: 189\u2013192.","journal-title":"Cell"},{"key":"BF1704081_CR16","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1089\/104303401750195935","volume":"12","author":"D Farson","year":"2001","unstructured":"Farson D, Witt R, McGuinness R et al. A new-generation stable inducible packaging cell line for lentiviral vectors. Hum Gene Ther 2001; 12: 981\u2013997.","journal-title":"Hum Gene Ther"},{"key":"BF1704081_CR17","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1006\/mthe.2002.0571","volume":"5","author":"SP Zielske","year":"2002","unstructured":"Zielske SP, Gerson SL . Lentiviral transduction of P140K MGMT into human CD34(+) hematopoietic progenitors at low multiplicity of infection confers significant resistance to BG\/BCNU and allows selection in vitro. Mol Ther 2002; 5: 381\u2013387.","journal-title":"Mol Ther"},{"key":"BF1704081_CR18","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1126\/science.283.5402.682","volume":"283","author":"H Miyoshi","year":"1999","unstructured":"Miyoshi H, Smith KA, Mosier DE et al. Transduction of human CD34+ cells that mediate long-term engraftment of NOD\/SCID mice by HIV vectors. Science 1999; 283: 682\u2013686.","journal-title":"Science"},{"key":"BF1704081_CR19","doi-asserted-by":"crossref","first-page":"3725","DOI":"10.1182\/blood.V96.12.3725.h8003725_3725_3733","volume":"96","author":"NB Woods","year":"2000","unstructured":"Woods NB, Fahlman C, Mikkola H et al. Lentiviral gene transfer into primary and secondary NOD\/SCID repopulating cells. Blood 2000; 96: 3725\u20133733.","journal-title":"Blood"},{"key":"BF1704081_CR20","doi-asserted-by":"publisher","first-page":"876","DOI":"10.1038\/nm0896-876","volume":"2","author":"H Hanenberg","year":"1996","unstructured":"Hanenberg H, Xiao XL, Dilloo D et al. Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells. Nat Med 1996; 2: 876\u2013882.","journal-title":"Nat Med"},{"key":"BF1704081_CR21","doi-asserted-by":"publisher","first-page":"2193","DOI":"10.1089\/hum.1997.8.18-2193","volume":"8","author":"H Hanenberg","year":"1997","unstructured":"Hanenberg H, Hashino K, Konishi H et al. Optimization of fibronectin-assisted retroviral gene transfer into human CD34+ hematopoietic cells. Hum Gene Ther 1997; 8: 2193\u20132206.","journal-title":"Hum Gene Ther"},{"key":"BF1704081_CR22","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1016\/S0301-472X(99)00031-4","volume":"27","author":"LJ Murray","year":"1999","unstructured":"Murray LJ, Young JC, Osborne LJ et al. Thrombopoietin, flt3, and kit ligands together suppress apoptosis of human mobilized CD34+ cells and recruit primitive CD34+ Thy-1+ cells into rapid division. Exp Hematol 1999; 27: 1019\u20131028.","journal-title":"Exp Hematol"},{"key":"BF1704081_CR23","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1006\/mthe.2000.0216","volume":"2","author":"AJ Schilz","year":"2000","unstructured":"Schilz AJ, Schiedlmeier B, Kuhlcke K et al. MDR1 gene expression in NOD\/SCID repopulating cells after retroviral gene transfer under clinically relevant conditions. Mol Ther 2000; 2: 609\u2013618.","journal-title":"Mol Ther"},{"issue":"Suppl 2","key":"BF1704081_CR24","doi-asserted-by":"publisher","first-page":"S118","DOI":"10.1038\/sj.bmt.1702369","volume":"25","author":"B Schiedlmeier","year":"2000","unstructured":"Schiedlmeier B, Wermann K, Kuhlcke K et al. Human multidrug resistance-1 gene transfer to long-term repopulating human mobilized peripheral blood progenitor cells. Bone Marrow Transplant 2000; 25(Suppl 2): S118\u2013S124.","journal-title":"Bone Marrow Transplant"},{"key":"BF1704081_CR25","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1084\/jem.176.4.1125","volume":"176","author":"RE Donahue","year":"1992","unstructured":"Donahue RE, Kessler SW, Bodine D et al. Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer. J Exp Med 1992; 176: 1125\u20131135.","journal-title":"J Exp Med"},{"key":"BF1704081_CR26","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.1182\/blood.V92.7.2269","volume":"92","author":"KD Bunting","year":"1998","unstructured":"Bunting KD, Galipeau J, Topham D et al. Transduction of murine bone marrow cells with an MDR1 vector enables ex vivo stem cell expansion, but these expanded grafts cause a myeloproliferative syndrome in transplanted mice. Blood 1998; 92: 2269\u20132279.","journal-title":"Blood"},{"key":"BF1704081_CR27","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1038\/76225","volume":"6","author":"R Abonour","year":"2000","unstructured":"Abonour R, Williams DA, Einhorn L et al. Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells. Nat Med 2000; 6: 652\u2013658.","journal-title":"Nat Med"},{"key":"BF1704081_CR28","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1086\/501711","volume":"21","author":"ME Evans","year":"2000","unstructured":"Evans ME, Jordan CT, Chang SM et al. Clinical infection control in gene therapy: a multidisciplinary conference. Infect Control Hosp Epidemiol 2000; 21: 659\u2013673.","journal-title":"Infect Control Hosp Epidemiol"},{"key":"BF1704081_CR29","doi-asserted-by":"publisher","first-page":"1134","DOI":"10.1016\/0140-6736(93)92122-A","volume":"342","author":"MK Brenner","year":"1993","unstructured":"Brenner MK, Rill DR, Holladay MS et al. Gene marking to determine whether autologous marrow infusion restores long-term haemopoiesis in cancer patients. Lancet 1993; 342: 1134\u20131137.","journal-title":"Lancet"},{"key":"BF1704081_CR30","doi-asserted-by":"crossref","first-page":"3048","DOI":"10.1182\/blood.V85.11.3048.bloodjournal85113048","volume":"85","author":"CE Dunbar","year":"1995","unstructured":"Dunbar CE, Cottler-Fox M, O'Shaughnessy JA et al. Retrovirally marked CD34-enriched peripheral blood and bone marrow cells contribute to long-term engraftment after autologous transplantation. Blood 1995; 85: 3048\u20133057.","journal-title":"Blood"},{"key":"BF1704081_CR31","doi-asserted-by":"publisher","first-page":"1953","DOI":"10.1089\/10430349950017310","volume":"10","author":"AK Stewart","year":"1999","unstructured":"Stewart AK, Sutherland DR, Nanji S et al. Engraftment of gene-marked hematopoietic progenitors in myeloma patients after transplant of autologous long-term marrow cultures. Hum Gene Ther 1999; 10: 1953\u20131964.","journal-title":"Hum Gene Ther"},{"key":"BF1704081_CR32","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1126\/science.270.5235.475","volume":"270","author":"RM Blaese","year":"1995","unstructured":"Blaese RM, Culver KW, Miller AD et al. T lymphocyte-directed gene therapy for ADA- SCID: initial trial results after 4 years. Science 1995; 270: 475\u2013480.","journal-title":"Science"},{"key":"BF1704081_CR33","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1182\/blood.V91.1.30","volume":"91","author":"M Onodera","year":"1998","unstructured":"Onodera M, Ariga T, Kawamura N et al. Successful peripheral T-lymphocyte-directed gene transfer for a patient with severe combined immune deficiency caused by adenosine deaminase deficiency. Blood 1998; 91: 30\u201336.","journal-title":"Blood"},{"key":"BF1704081_CR34","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1126\/science.270.5235.470","volume":"270","author":"C Bordignon","year":"1995","unstructured":"Bordignon C, Notarangelo LD, Nobili N et al. Gene therapy in peripheral blood lymphocytes and bone marrow for ADA- immunodeficient patients. Science 1995; 270: 470\u2013475.","journal-title":"Science"},{"key":"BF1704081_CR35","first-page":"179","volume":"3","author":"PM Hoogerbrugge","year":"1996","unstructured":"Hoogerbrugge PM, van Beusechem VW, Fischer A et al. Bone marrow gene transfer in three patients with adenosine deaminase deficiency. Gene Therapy 1996; 3: 179\u2013183.","journal-title":"Gene Therapy"},{"key":"BF1704081_CR36","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1038\/nm1095-1017","volume":"1","author":"DB Kohn","year":"1995","unstructured":"Kohn DB, Weinberg KI, Nolta JA et al. Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency. Nat Med 1995; 1: 1017\u20131023.","journal-title":"Nat Med"},{"key":"BF1704081_CR37","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1126\/science.288.5466.669","volume":"288","author":"M Cavazzana-Calvo","year":"2000","unstructured":"Cavazzana-Calvo M, Hacein-Bey S, de Saint Basile G et al. Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease. Science 2000; 288: 669\u2013672.","journal-title":"Science"},{"key":"BF1704081_CR38","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1056\/NEJMoa012616","volume":"346","author":"S Hacein-Bey-Abina","year":"2002","unstructured":"Hacein-Bey-Abina S, Le Deist F, Carlier F et al. Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy. N Engl J Med 2002; 346: 1185\u20131193.","journal-title":"N Engl J Med"},{"key":"BF1704081_CR39","doi-asserted-by":"publisher","first-page":"1189","DOI":"10.1038\/nm1102-1189","volume":"8","author":"L Bonetta","year":"2002","unstructured":"Bonetta L . Leukemia causes tightening of gene therapy controls. Nat Med 2002; 8: 1189.","journal-title":"Nat Med"},{"issue":"Suppl 2","key":"BF1704081_CR40","first-page":"S18","volume":"179","author":"HL Malech","year":"1999","unstructured":"Malech HL . Progress in gene therapy for chronic granulomatous disease. J Infect Dis 1999; 179(Suppl 2): S18\u2013S325.","journal-title":"J Infect Dis"},{"key":"BF1704081_CR41","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1023\/A:1022548232735","volume":"24","author":"JA Barranger","year":"1999","unstructured":"Barranger JA, Rice EO, Swaney WP . Gene transfer approaches to the lysosomal storage disorders. Neurochem Res 1999; 24: 601\u2013615.","journal-title":"Neurochem Res"},{"key":"BF1704081_CR42","doi-asserted-by":"publisher","first-page":"2629","DOI":"10.1089\/hum.1998.9.17-2629","volume":"9","author":"CE Dunbar","year":"1998","unstructured":"Dunbar CE, Kohn DB, Schiffmann R et al. Retroviral transfer of the glucocerebrosidase gene into CD34+ cells from patients with Gaucher disease: in vivo detection of transduced cells without myeloablation. Hum Gene Ther 1998; 9: 2629\u20132640.","journal-title":"Hum Gene Ther"},{"key":"BF1704081_CR43","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1038\/360749a0","volume":"360","author":"JH Wolfe","year":"1992","unstructured":"Wolfe JH, Sands MS, Barker JE et al. Reversal of pathology in murine mucopolysaccharidosis type VII by somatic cell gene transfer. Nature 1992; 360: 749\u2013753.","journal-title":"Nature"},{"key":"BF1704081_CR44","first-page":"379","volume":"43","author":"CE Walsh","year":"1995","unstructured":"Walsh CE, Mann MM, Emmons RV et al. Transduction of CD34-enriched human peripheral and umbilical cord blood progenitors using a retroviral vector with the Fanconi anemia group C gene. J Investig Med 1995; 43: 379\u2013385.","journal-title":"J Investig Med"},{"key":"BF1704081_CR45","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1089\/hum.1994.5.7-891","volume":"5","author":"JA O'Shaughnessy","year":"1994","unstructured":"O'Shaughnessy JA, Cowan KH, Nienhuis AW et al. Retroviral mediated transfer of the human multidrug resistance gene (MDR-1) into hematopoietic stem cells during autologous transplantation after intensive chemotherapy for metastatic breast cancer. Hum Gene Ther 1994; 5: 891\u2013911.","journal-title":"Hum Gene Ther"},{"key":"BF1704081_CR46","doi-asserted-by":"publisher","first-page":"15346","DOI":"10.1073\/pnas.93.26.15346","volume":"93","author":"EG Hanania","year":"1996","unstructured":"Hanania EG, Giles RE, Kavanagh J et al. Results of MDR-1 vector modification trial indicate that granulocyte\/macrophage colony-forming unit cells do not contribute to posttransplant hematopoietic recovery following intensive systemic therapy. Proc Natl Acad Sci USA 1996; 93: 15346\u201315351.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF1704081_CR47","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1200\/JCO.1998.16.1.165","volume":"16","author":"C Hesdorffer","year":"1998","unstructured":"Hesdorffer C, Ayello J, Ward M et al. Phase I trial of retroviral-mediated transfer of the human MDR1 gene as marrow chemoprotection in patients undergoing high-dose chemotherapy and autologous stem-cell transplantation. J Clin Oncol 1998; 16: 165\u2013172.","journal-title":"J Clin Oncol"},{"key":"BF1704081_CR48","first-page":"1619","volume":"5","author":"KH Cowan","year":"1999","unstructured":"Cowan KH, Moscow JA, Huang H et al. Paclitaxel chemotherapy after autologous stem-cell transplantation and engraftment of hematopoietic cells transduced with a retrovirus containing the multidrug resistance complementary DNA (MDR1) in metastatic breast cancer patients. Clin Cancer Res 1999; 5: 1619\u20131628.","journal-title":"Clin Cancer Res"},{"key":"BF1704081_CR49","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1182\/blood.V94.1.52.413k35_52_61","volume":"94","author":"JA Moscow","year":"1999","unstructured":"Moscow JA, Huang H, Carter C et al. Engraftment of MDR1 and NeoR gene-transduced hematopoietic cells after breast cancer chemotherapy. Blood 1999; 94: 52\u201361.","journal-title":"Blood"},{"key":"BF1704081_CR50","first-page":"163","volume":"5","author":"J Reese","year":"1999","unstructured":"Reese J, Davis B, Liu L, Gerson SL . Simultaneous protection of G156A methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and sensitization of tumor cells using O6-benzylguanine and temozolomide. Clin Cancer Res 1999; 5: 163\u2013169.","journal-title":"Clin Cancer Res"},{"key":"BF1704081_CR51","doi-asserted-by":"crossref","first-page":"3078","DOI":"10.1182\/blood.V95.10.3078","volume":"95","author":"BM Davis","year":"2000","unstructured":"Davis BM, Ko\u00e7 ON, Gerson SL . Limiting numbers of G156A O6- methylguanine-DNA methyltransferase-transduced marrow progenitors repopulate nonmyeloablated mice after drug selection. Blood 2000; 95: 3078\u20133084.","journal-title":"Blood"}],"container-title":["Bone Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/1704081","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1704081.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1704081.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,23]],"date-time":"2022-03-23T23:32:58Z","timestamp":1648078378000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1704081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,6,23]]},"references-count":51,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2003,7,1]]}},"alternative-id":["BF1704081"],"URL":"https:\/\/doi.org\/10.1038\/sj.bmt.1704081","relation":{},"ISSN":["0268-3369","1476-5365"],"issn-type":[{"value":"0268-3369","type":"print"},{"value":"1476-5365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,6,23]]},"assertion":[{"value":"23 June 2003","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}