{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T13:33:06Z","timestamp":1758634386800},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2004,6,7]],"date-time":"2004-06-07T00:00:00Z","timestamp":1086566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2004,6,7]],"date-time":"2004-06-07T00:00:00Z","timestamp":1086566400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bone Marrow Transplant"],"published-print":{"date-parts":[[2004,8,1]]},"DOI":"10.1038\/sj.bmt.1704569","type":"journal-article","created":{"date-parts":[[2004,6,14]],"date-time":"2004-06-14T09:08:15Z","timestamp":1087204095000},"page":"249-255","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Isolated HLA-C mismatches in unrelated donor transplantation for CML"],"prefix":"10.1038","volume":"34","author":[{"given":"J-M","family":"Tiercy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Passweg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"van Biezen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Zander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Kr\u00f6ger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Gratwohl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Chapuis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Helg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Brinch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Cornelissen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Oudshoorn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Ruutu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Volin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Niederwieser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Roosnek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the Chronic Leukemia Working Party of the European Blood and Marrow Transplant Group (EBMT)","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2004,6,7]]},"reference":[{"key":"BF1704569_CR1","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1182\/blood.V83.1.280.280","volume":"83","author":"P Santamaria","year":"1994","unstructured":"Santamaria P, Reinsmoen NL, Lindstrom AL et al. Frequent HLA class I and DP sequence mismatches in serologically (HLA-A, HLA-B, HLA-DR) and molecularly (HLA-DRB1, HLA-DQA1, HLA-DQB1) HLA-identical unrelated bone marrow transplant pairs. Blood 1994; 83: 280\u2013287.","journal-title":"Blood"},{"key":"BF1704569_CR2","first-page":"641","volume":"16","author":"N Rufer","year":"1995","unstructured":"Rufer N, Tiercy J-M, Breur-Vriesendorp B et al. Histoincompatibilities in ABDR-matched unrelated donor recipient combinations. Bone Marrow Transplant 1995; 16: 641\u2013646.","journal-title":"Bone Marrow Transplant"},{"key":"BF1704569_CR3","doi-asserted-by":"crossref","first-page":"4864","DOI":"10.1182\/blood.V92.12.4864","volume":"92","author":"I Scott","year":"1998","unstructured":"Scott I, O'Shea J, Bunce M et al. Molecular typing shows a high level of HLA class I incompatibility in serologically well matched donor\/patient pairs: implications for unrelated bone marrow donor selection. Blood 1998; 92: 4864\u20134871.","journal-title":"Blood"},{"key":"BF1704569_CR4","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1182\/blood.V93.1.399","volume":"93","author":"VK Prasad","year":"1999","unstructured":"Prasad VK, Kernan NA, Heller G et al. DNA typing for HLA-A and HLA-B identifies disparities between patients and unrelated donors matched by HLA-A and HLA-B serology and HLA-DRB1. Blood 1999; 93: 399\u2013409.","journal-title":"Blood"},{"key":"BF1704569_CR5","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1182\/blood.V81.1.249.249","volume":"81","author":"PG Beatty","year":"1993","unstructured":"Beatty PG, Anasetti C, Hansen JA et al. Marrow transplantation from unrelated donors for treatment of hematologic malignancies: effect of mismatching for one HLA locus. Blood 1993; 81: 249\u2013253.","journal-title":"Blood"},{"key":"BF1704569_CR6","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1056\/NEJM199303043280901","volume":"328","author":"NA Kernan","year":"1993","unstructured":"Kernan NA, Bartsch G, Ash R et al. Analysis of 462 transplantations from unrelated donors facilitated by the national marrow donor program. N Engl J Med 1993; 328: 593\u2013602.","journal-title":"N Engl J Med"},{"key":"BF1704569_CR7","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1182\/blood.V86.4.1606.bloodjournal8641606","volume":"86","author":"EW Petersdorf","year":"1995","unstructured":"Petersdorf EW, Longton GM, Anasetti C et al. The significance of HLA-DRB1 matching on clinical outcome after HLA-A, B, DR identical unrelated donor marrow transplantation. Blood 1995; 86: 1606\u20131613.","journal-title":"Blood"},{"key":"BF1704569_CR8","doi-asserted-by":"crossref","first-page":"3590","DOI":"10.1182\/blood.V86.9.3590.bloodjournal8693590","volume":"86","author":"A Spencer","year":"1995","unstructured":"Spencer A, Szydlo RM, Brookes PA et al. Bone marrow transplantation for chronic myeloid leukemia with volunteer unrelated donors using ex vivo or in vivo T-cell depletion: major prognostic impact of HLA class I identity between donor and recipient. Blood 1995; 86: 3590\u20133597.","journal-title":"Blood"},{"key":"BF1704569_CR9","doi-asserted-by":"crossref","first-page":"4455","DOI":"10.1182\/blood.V87.10.4455.bloodjournal87104455","volume":"87","author":"DE Speiser","year":"1996","unstructured":"Speiser DE, Tiercy J-M, Rufer N et al. High resolution HLA matching associated with decreased mortality after unrelated bone marrow transplantation. Blood 1996; 87: 4455\u20134462.","journal-title":"Blood"},{"key":"BF1704569_CR10","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.1056\/NEJM199810223391701","volume":"339","author":"T Sasazuki","year":"1998","unstructured":"Sasazuki T, Juji T, Morishima Y et al. Effect of matching of class I HLA alleles on clinical outcome after transplantation of hematopoietic stem cells from an unrelated donor. Japan Marrow Donor Program. N Engl J Med 1998; 339: 1177\u20131185.","journal-title":"N Engl J Med"},{"key":"BF1704569_CR11","doi-asserted-by":"crossref","first-page":"3515","DOI":"10.1182\/blood.V92.10.3515","volume":"92","author":"EW Petersdorf","year":"1998","unstructured":"Petersdorf EW, Gooley TA, Anasetti C et al. Optimizing outcome after unrelated marrow transplantation by comprehensive matching of HLA class I and II alleles in the donor and recipient. Blood 1998; 92: 3515\u20133520.","journal-title":"Blood"},{"key":"BF1704569_CR12","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1056\/NEJM199804023381405","volume":"338","author":"JA Hansen","year":"1998","unstructured":"Hansen JA, Gooley TA, Martin PJ et al. Bone marrow transplants from unrelated donors for patients with chronic myeloid leukemia. N Engl J Med 1998; 338: 962\u2013968.","journal-title":"N Engl J Med"},{"key":"BF1704569_CR13","doi-asserted-by":"publisher","first-page":"1794","DOI":"10.1056\/NEJMoa011826","volume":"345","author":"EW Petersdorf","year":"2001","unstructured":"Petersdorf EW, Hansen JA, Martin PJ et al. Major-histocompatibility-complex class I alleles and antigens in hematopoietic-cell transplantation. N Engl J Med 2001; 345: 1794\u20131800.","journal-title":"N Engl J Med"},{"key":"BF1704569_CR14","doi-asserted-by":"publisher","first-page":"2922","DOI":"10.1182\/blood.V98.10.2922","volume":"98","author":"EW Petersdorf","year":"2001","unstructured":"Petersdorf EW, Kollman C, Hurley CK et al. Effect of HLA class II gene disparity on clinical outcome in unrelated donor hematopoietic cell transplantation for chronic myeloid leukemia: the US National Marrow Donor Program Experience. Blood 2001; 98: 2922\u20132929.","journal-title":"Blood"},{"key":"BF1704569_CR15","doi-asserted-by":"publisher","first-page":"1971","DOI":"10.1182\/blood.V99.6.1971","volume":"99","author":"DJ Weisdorf","year":"2002","unstructured":"Weisdorf DJ, Anasetti C, Antin JH et al. Allogeneic bone marrow transplantation for chronic myelogenous leukemia: comparative analysis of unrelated versus matched sibling donor transplantation. Blood 2002; 99: 1971\u20131977.","journal-title":"Blood"},{"key":"BF1704569_CR16","doi-asserted-by":"publisher","first-page":"4200","DOI":"10.1182\/blood.V99.11.4200","volume":"99","author":"Y Morishima","year":"2002","unstructured":"Morishima Y, Sasazuki T, Inoko H et al. The clinical significance of human leukocyte antigen (HLA) allele compatibility in patients receiving a marrow transplant from serologically HLA-A, HLA-B, and HLA-DR matched unrelated donors. Blood 2002; 99: 4200\u20134206.","journal-title":"Blood"},{"key":"BF1704569_CR17","first-page":"891","volume":"18","author":"A Nagler","year":"1996","unstructured":"Nagler A, Brautbar C, Slavin S, Bishara A . Bone marrow transplantation using unrelated and family related donors: the impact of HLA-C disparity. Bone Marrow Transplant 1996; 18: 891\u2013897.","journal-title":"Bone Marrow Transplant"},{"key":"BF1704569_CR18","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1182\/blood.V89.5.1818","volume":"89","author":"EW Petersdorf","year":"1997","unstructured":"Petersdorf EW, Longton GM, Anasetti C et al. Association of HLA-C disparity with graft failure after marrow transplantation from unrelated donors. Blood 1997; 89: 1818\u20131823.","journal-title":"Blood"},{"key":"BF1704569_CR19","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1097\/00062752-199911000-00002","volume":"6","author":"E Roosnek","year":"1999","unstructured":"Roosnek E, Tiercy J-M . The search for an unrelated HLA compatible stem cell donor. Curr Opin Hematol 1999; 6: 365\u2013370.","journal-title":"Curr Opin Hematol"},{"key":"BF1704569_CR20","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/S0966-3274(02)00068-0","volume":"10","author":"JM Tiercy","year":"2002","unstructured":"Tiercy JM, Villard J, Roosnek E . Selection of unrelated bone marrow donors by serology, molecular typing and cellular assays. Transpl Immunol 2002; 10: 215\u2013221.","journal-title":"Transpl Immunol"},{"key":"BF1704569_CR21","doi-asserted-by":"publisher","first-page":"2085","DOI":"10.1084\/jem.181.6.2085","volume":"181","author":"JA McCutcheon","year":"1995","unstructured":"McCutcheon JA, Gumperz J, Smith KD et al. Low HLA-C expression at cell surfaces correlates with increased turnover of heavy chain mRNA. J Exp Med 1995; 181: 2085\u20132095.","journal-title":"J Exp Med"},{"key":"BF1704569_CR22","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1182\/blood.V94.1.333.413a31_333_339","volume":"94","author":"L Ruggeri","year":"1999","unstructured":"Ruggeri L, Capanni M, Casucci M et al. Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation. Blood 1999; 94: 333\u2013339.","journal-title":"Blood"},{"key":"BF1704569_CR23","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1038\/sj.bmt.1702529","volume":"26","author":"J-M Tiercy","year":"2000","unstructured":"Tiercy J-M, Bujan-Lose M, Chapuis B et al. Bone marrow transplantation with unrelated donors: what is the probability to identify an HLA-A\/B\/CwDRB1\/B3\/B5\/DQB1-matched donor? Bone Marrow Transplant 2000; 26: 441.","journal-title":"Bone Marrow Transplant"},{"key":"BF1704569_CR24","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1034\/j.1399-0039.2003.00089.x","volume":"62","author":"M Schaffer","year":"2003","unstructured":"Schaffer M, Aldener-Cannava A, Remberger M et al. Roles of HLA-B, HLA-C and HLA-DPA1 incompatibilities in the outcome of unrelated stem-cell transplantation. Tissue Antigens 2003; 62: 243\u2013250.","journal-title":"Tissue Antigens"},{"key":"BF1704569_CR25","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1097\/00007890-200109150-00030","volume":"72","author":"A van der Meer","year":"2001","unstructured":"van der Meer A, Allebes WA, Paardekooper J et al. HLA-C mismatches induce strong cytotoxic T-cell reactivity in the presence of an additional DRB\/DQB mismatch and affect NK cell-mediated alloreactivity. Transplantation 2001; 72: 923\u2013929.","journal-title":"Transplantation"},{"key":"BF1704569_CR26","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1046\/j.1365-2141.1998.00790.x","volume":"102","author":"G Dini","year":"1998","unstructured":"Dini G, Lamparelli T, Rondelli R et al. Unrelated donor marrow transplantation for chronic myelogenous leukaemia. Br J Haematol 1998; 102: 544\u2013552.","journal-title":"Br J Haematol"},{"key":"BF1704569_CR27","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1182\/blood.V99.3.806","volume":"99","author":"WR Drobyski","year":"2002","unstructured":"Drobyski WR, Klein J, Flomenberg N et al. Superior survival associated with transplantation of matched unrelated versus one-antigen-mismatched unrelated or highly human leukocyte antigen-disparate haploidentical family donor marrow grafts for the treatment of hematologic malignancies: establishing a treatment algorithm for recipients of alternative donor grafts. Blood 2002; 99: 806\u2013814.","journal-title":"Blood"},{"key":"BF1704569_CR28","doi-asserted-by":"publisher","first-page":"3825","DOI":"10.1182\/blood-2002-04-1197","volume":"100","author":"SM Davies","year":"2002","unstructured":"Davies SM, Ruggieri L, DeFor T et al. Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants. Killer immunoglobulin-like receptor. Blood 2002; 100: 3825\u20133827.","journal-title":"Blood"},{"key":"BF1704569_CR29","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1111\/j.0001-2815.2004.00182.x","volume":"63","author":"A Bishara","year":"2004","unstructured":"Bishara A, De Santis D, Witt CC et al. The beneficial role of inhibitory KIR genes of HLA class I NK epitopes in haploidentically mismatched stem cell allografts may be masked by residual donor-alloreactive T cells causing GVHD. Tissue Antigens 2004; 63: 204\u2013211.","journal-title":"Tissue Antigens"},{"key":"BF1704569_CR30","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1038\/sj.bmt.1704029","volume":"31","author":"BE Shaw","year":"2003","unstructured":"Shaw BE, Potter MN, Mayor NP et al. The degree of matching at HLA-DPB1 predicts for acute graft-versus-host disease and disease relapse following haematopoietic stem cell transplantation. Bone Marrow Transplant 2003; 31: 1001\u20131008.","journal-title":"Bone Marrow Transplant"}],"container-title":["Bone Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/1704569","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1704569.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1704569.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,23]],"date-time":"2022-03-23T23:15:22Z","timestamp":1648077322000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1704569"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6,7]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,8,1]]}},"alternative-id":["BF1704569"],"URL":"https:\/\/doi.org\/10.1038\/sj.bmt.1704569","relation":{},"ISSN":["0268-3369","1476-5365"],"issn-type":[{"type":"print","value":"0268-3369"},{"type":"electronic","value":"1476-5365"}],"subject":[],"published":{"date-parts":[[2004,6,7]]},"assertion":[{"value":"10 December 2003","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 March 2004","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 June 2004","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}