{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T13:34:30Z","timestamp":1776692070138,"version":"3.51.2"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2005,11,7]],"date-time":"2005-11-07T00:00:00Z","timestamp":1131321600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2005,11,7]],"date-time":"2005-11-07T00:00:00Z","timestamp":1131321600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bone Marrow Transplant"],"published-print":{"date-parts":[[2006,1,1]]},"DOI":"10.1038\/sj.bmt.1705224","type":"journal-article","created":{"date-parts":[[2005,11,7]],"date-time":"2005-11-07T05:08:05Z","timestamp":1131340085000},"page":"175-181","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Autologous stem cell transplantation for high-risk Ewing's sarcoma and other pediatric solid tumors"],"prefix":"10.1038","volume":"37","author":[{"given":"C J","family":"Fraser","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B J","family":"Weigel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J P","family":"Perentesis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K E","family":"Dusenbery","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T E","family":"DeFor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K S","family":"Baker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M R","family":"Verneris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2005,11,7]]},"reference":[{"key":"BF1705224_CR1","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1097\/00001622-200403000-00006","volume":"16","author":"PA Meyers","year":"2004","unstructured":"Meyers PA . High-dose therapy with autologous stem cell rescue for pediatric sarcomas. Curr Opin Oncol 2004; 16: 120\u2013125.","journal-title":"Curr Opin Oncol"},{"key":"BF1705224_CR2","first-page":"1354","volume-title":"Thomas\u2019 Hematopoietic Cell Transplantation","author":"AR Chen","year":"2004","unstructured":"Chen AR, Civin CI . Hematopoietic cell transplantation for pediatric patients with solid tumors. In: Blume KJ, Forman SJ, Appelbaum FR (eds). Thomas\u2019 Hematopoietic Cell Transplantation. Blackwell Publishing: Massachusetts, 2004, pp 1354\u20131368."},{"key":"BF1705224_CR3","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/0002-9343(80)90472-6","volume":"69","author":"EJ Frei","year":"1980","unstructured":"Frei EJ, Canellos GP . Dose: a critical factor in cancer chemotherapy. Am J Med 1980; 69: 585\u2013594.","journal-title":"Am J Med"},{"key":"BF1705224_CR4","first-page":"91","volume":"59","author":"JA Houghton","year":"1985","unstructured":"Houghton JA, Cook RL, Lutz PJ, Houghton PJ . Melphalan: a potential new agent in the treatment of childhood rhabdomyosarcoma. Cancer Treat Rep 1985; 59: 91\u201396.","journal-title":"Cancer Treat Rep"},{"key":"BF1705224_CR5","first-page":"241","volume":"63","author":"M Cornbleet","year":"1981","unstructured":"Cornbleet M, Corringham HG, Prentice HG, Boesen EM, McElwain TJ . Treatment of Ewing's sarcoma with high dose melphalan and autologous bone marrow rescue. Cancer Treat Rep 1981; 63: 241\u2013244.","journal-title":"Cancer Treat Rep"},{"key":"BF1705224_CR6","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1002\/1097-0142(19840915)54:1+<1204::AID-CNCR2820541318>3.0.CO;2-Z","volume":"54","author":"EA Gehan","year":"1984","unstructured":"Gehan EA . Dose response relationship in clinical oncology. Cancer 1984; 54: 1204\u20131207.","journal-title":"Cancer"},{"key":"BF1705224_CR7","first-page":"106","volume":"7","author":"O Hartmann","year":"1991","unstructured":"Hartmann O, Vassal G, Valteau D, Brugieres L, Lemerle J . Autologous bone marrow transplantation in pediatric solid tumours: phase II studies. Bone Marrow Transplant 1991; 7: 106\u2013111.","journal-title":"Bone Marrow Transplant"},{"key":"BF1705224_CR8","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1038\/sj.bmt.1701950","volume":"24","author":"JP Perentesis","year":"1999","unstructured":"Perentesis JP, Katsanis E, DeFor TE, Neglia J, Ramsay N . Autologous stem cell transplantation for high risk pediatric solid tumors. Bone Marrow Transplant 1999; 24: 609\u2013615.","journal-title":"Bone Marrow Transplant"},{"key":"BF1705224_CR9","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","volume":"53","author":"EL Kaplan","year":"1958","unstructured":"Kaplan EL, Meier P . Nonparametric estimation from incomplete observations. J Amer Stat Assoc 1958; 53: 457\u2013481.","journal-title":"J Amer Stat Assoc"},{"key":"BF1705224_CR10","first-page":"457","volume":"16","author":"DY Lin","year":"1997","unstructured":"Lin DY . Non-parametric inference for cumulative incidence functions in competing risks studies. Stat Med 1997; 16: 457\u2013481.","journal-title":"Stat Med"},{"key":"BF1705224_CR11","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1056\/NEJM199910143411601","volume":"341","author":"KK Matthay","year":"1999","unstructured":"Matthay KK, Villablanca JG, Seeger RC, Stram DO, Harris RE, Ramsay NK et al. Treatment of high risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer Group. New Engl J Med 1999; 341: 1165\u20131173.","journal-title":"New Engl J Med"},{"key":"BF1705224_CR12","doi-asserted-by":"publisher","first-page":"3295","DOI":"10.1200\/JCO.1998.16.10.3295","volume":"16","author":"F Pein","year":"1998","unstructured":"Pein F, Michon J, Valteau-Couanet D, Quintana P, Frappaz D, Vannier JP et al. High dose melphalan, etoposide and carboplatin followed by autologous stem-cell rescue in pediatric high-risk recurrent Wilm's tumor: a French Society of Pediatric Oncology Study. J Clin Oncol 1998; 16: 3295\u20133301.","journal-title":"J Clin Oncol"},{"key":"BF1705224_CR13","doi-asserted-by":"publisher","first-page":"2885","DOI":"10.1200\/JCO.2004.09.073","volume":"22","author":"AD Campbell","year":"2004","unstructured":"Campbell AD, Cohn SL, Reynolds M, Seshadri R, Morgan E, Geissler G et al. Treatment of relapsed Wilm's tumor with high dose therapy and autologous hematopoietic stem cell rescue: the experience at Children's Memorial Hospital. J Clin Oncol 2004; 22: 2885\u20132890.","journal-title":"J Clin Oncol"},{"key":"BF1705224_CR14","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1038\/sj.bmt.1703771","volume":"30","author":"B Kremens","year":"2002","unstructured":"Kremens B, Gruhn B, Klingebiel T, Hasan C, Laws HJ, Koscielniak E et al. High-dose chemotherapy with autologous stem cell rescue in children with nephroblastoma. Bone Marrow Transplant 2002; 30: 893\u2013898.","journal-title":"Bone Marrow Transplant"},{"key":"BF1705224_CR15","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1046\/j.1442-200X.2002.01549.x","volume":"44","author":"S Nishimura","year":"2002","unstructured":"Nishimura S, Sato T, Fujita N, Yamaoka H, Hiyama E, Yokoyama T et al. High dose chemotherapy in children with metastatic hepatoblastoma. Pediatr Int 2002; 44: 300\u2013305.","journal-title":"Pediatr Int"},{"key":"BF1705224_CR16","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1097\/00043426-200401000-00011","volume":"26","author":"RF Jubran","year":"2004","unstructured":"Jubran RF, Erdreich-Epstein A, Butturini A, Murphree AL, Villablanca JG . Approaches to treatment for extraocular retinoblastoma: Children's Hospital Los Angeles experience. J Pediatr Hematol Oncol 2004; 26: 31\u201334.","journal-title":"J Pediatr Hematol Oncol"},{"key":"BF1705224_CR17","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1038\/sj.bmt.1703832","volume":"31","author":"B Kremens","year":"2003","unstructured":"Kremens B, Wieland R, Reinhard H, Neubert D, Beck JD, Klingebiel T et al. High-dose chemotherapy with autologous stem cell rescue in children with retinoblastoma. Bone Marrow Transplant 2003; 31: 281\u2013284.","journal-title":"Bone Marrow Transplant"},{"key":"BF1705224_CR18","doi-asserted-by":"publisher","first-page":"1526","DOI":"10.1200\/JCO.1996.14.5.1526","volume":"14","author":"BH Kushner","year":"1996","unstructured":"Kushner BH, LaQuaglia MP, Wollner N, Meyers PA, Lindsley KL, Ghavimi F et al. Desmoplastic small round cell tumor: prolonged progression-free survival with aggressive multimodality therapy. J Clin Oncol 1996; 14: 1526\u20131531.","journal-title":"J Clin Oncol"},{"key":"BF1705224_CR19","first-page":"239a","volume":"24","author":"D Valteau-Couanet","year":"1996","unstructured":"Valteau-Couanet D, Kalifa C, Benhamou E . Phase II study of high dose thiotepa and hematopoietic stem cell transplantation support in children with metastatic osteosarcoma. Med Pediatr Oncol 1996; 24: 239a.","journal-title":"Med Pediatr Oncol"},{"key":"BF1705224_CR20","doi-asserted-by":"publisher","first-page":"2796","DOI":"10.1200\/JCO.1999.17.9.2796","volume":"17","author":"M Carli","year":"1999","unstructured":"Carli M, Colombatti R, Oberlin O, Stevens M, Masiero L, Frascella E et al. High-dose melphalan with autologous stem-cell rescue in metastatic rhabdomyosarcoma. J Clin Oncol 1999; 17: 2796\u20132803.","journal-title":"J Clin Oncol"},{"key":"BF1705224_CR21","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1056\/NEJMoa020890","volume":"384","author":"HE Grier","year":"2003","unstructured":"Grier HE, Krailo MD, Tarbell NJ, Link MP, Fryer CJ, Pritchard DJ et al. Addition of ifosfamide and etoposide to standard chemotherapy in Ewing's sarcoma and primitive neuroectodermal tumor of bone. N Engl J Med 2003; 384: 694\u2013701.","journal-title":"N Engl J Med"},{"key":"BF1705224_CR22","doi-asserted-by":"publisher","first-page":"2873","DOI":"10.1200\/JCO.2004.01.041","volume":"22","author":"JS Miser","year":"2004","unstructured":"Miser JS, Krailo MD, Tarbell NJ, Link MP, Fryer CJ, Pritchard DJ et al. Treatment of metastatic Ewing's sarcoma or primitive neuroectodermal tumor of bone: evaluation of combination ifosfamide and etoposide \u2013 a Children's Cancer Group and Pediatric Oncology Group study. J Clin Oncol 2004; 22: 2873\u20132876.","journal-title":"J Clin Oncol"},{"key":"BF1705224_CR23","doi-asserted-by":"publisher","first-page":"3104","DOI":"10.1200\/JCO.2000.18.17.3108","volume":"18","author":"SJ Cotterill","year":"2000","unstructured":"Cotterill SJ, Ahrens S, Paulussen M, Jurgens HF, Voute PA, Gadner H et al. Prognostic factors in Ewing's tumor of bone: analysis of 975 patients from the European Intergroup Co-operative Ewing's Sarcoma Study Group. J Clin Oncol 2000; 18: 3104\u20133108.","journal-title":"J Clin Oncol"},{"key":"BF1705224_CR24","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1002\/cncr.10192","volume":"94","author":"C Rodriguez-Galindo","year":"2002","unstructured":"Rodriguez-Galindo C, Billups CA, Kun LE, Rao BN, Pratt CB, Merchant TE et al. Survival after recurrence of Ewing tumors. The St Jude Children's Research Hospital Experience, 1979\u20131999. Cancer 2002; 94: 561\u2013569.","journal-title":"Cancer"},{"key":"BF1705224_CR25","doi-asserted-by":"publisher","first-page":"4354","DOI":"10.1200\/JCO.2005.05.105","volume":"23","author":"LM Barker","year":"2005","unstructured":"Barker LM, Pendergrass TW, Sanders JE, Hawkins DS . Survival after recurrence of Ewing's sarcoma family of tumors. J Clin Oncol 2005; 23: 4354\u20134362.","journal-title":"J Clin Oncol"},{"issue":"Suppl 5","key":"BF1705224_CR26","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1111\/j.1398-2265.2004.00185.x","volume":"8","author":"SA Kalambakas","year":"2004","unstructured":"Kalambakas SA, Moore TB, Feig SA . Megatherapy and stem cell transplantation for Ewing's family of tumors: a critical review of current literature. Pediatr Transplant 2004; 8 (Suppl 5): 83\u201388.","journal-title":"Pediatr Transplant"},{"key":"BF1705224_CR27","doi-asserted-by":"publisher","first-page":"1482","DOI":"10.1200\/JCO.1993.11.8.1482","volume":"11","author":"S Burdach","year":"1993","unstructured":"Burdach S, Jurgens H, Peters C, Nurnberger W, Mauz-Korholz C, Korholz D et al. Myeloablative radiochemotherapy and hematopoietic stem-cell rescue in poor prognosis Ewing's sarcoma. J Clin Oncol 1993; 11: 1482\u20131488.","journal-title":"J Clin Oncol"},{"key":"BF1705224_CR28","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/S1040-8428(01)00150-0","volume":"41","author":"G Rosti","year":"2002","unstructured":"Rosti G, Ferrante P, Ledermann J, Leyvraz S, Ladenstein R, Koscileniak E et al. High-dose chemotherapy for solid tumors: results of the EBMT. Crit Rev Oncol Hematol 2002; 41: 129\u2013140.","journal-title":"Crit Rev Oncol Hematol"},{"key":"BF1705224_CR29","doi-asserted-by":"publisher","first-page":"3072","DOI":"10.1200\/JCO.2003.12.039","volume":"16","author":"S Burdach","year":"2003","unstructured":"Burdach S, Meyer-Bahlburg A, Laws HJ, Haase R, van Kaik B, Metzner B et al. High-dose therapy for patients with primary multifocal and early relapsed Ewing's tumors: Results of two consecutive regimens assessing the role of total-body irradiation. J Clin Oncol 2003; 16: 3072\u20133078.","journal-title":"J Clin Oncol"},{"key":"BF1705224_CR30","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1200\/JCO.2001.19.3.870","volume":"19","author":"BH Kushner","year":"2001","unstructured":"Kushner BH, Meyers PA . How effective is dose-intensive\/myeloablative therapy against Ewing's sarcoma\/primitive neuroectodermal tumor metastatic to bone or bone marrow? The Memorial Sloan\u2013Kettering experience and a literature review. J Clin Oncol 2001; 19: 870\u2013880.","journal-title":"J Clin Oncol"},{"key":"BF1705224_CR31","doi-asserted-by":"publisher","first-page":"2812","DOI":"10.1200\/JCO.2001.19.11.2812","volume":"19","author":"PA Meyers","year":"2001","unstructured":"Meyers PA, Krailo MD, Ladanyi M, Chan KW, Sailer SL, Dickman PS et al. High-dose melphalan, etoposide, total body irradiation, and autologous stem cell reconstitution as consolidation therapy for high risk Ewing's sarcoma does not improve prognosis. J Clin Oncol 2001; 19: 2812\u20132820.","journal-title":"J Clin Oncol"},{"key":"BF1705224_CR32","first-page":"2837","volume":"54","author":"M Ladanyi","year":"1994","unstructured":"Ladanyi M, Gerald W . Fusion of the EWS and WT1 genes in the desmoplastic small round cell tumor. Cancer Res 1994; 54: 2837\u20132840.","journal-title":"Cancer Res"},{"key":"BF1705224_CR33","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1097\/00000478-199106000-00001","volume":"15","author":"WL Gerald","year":"1991","unstructured":"Gerald WL, Miller HK, Battifora H, Miettinen M, Silva EG, Rosai J et al. Intra-abdominal desmoplastic small round cell tumor: report of 19 cases of a distinctive type of high grade polyphenotypic malignancy affecting young individuals. Am J Surg Pathol 1991; 15: 499\u2013513.","journal-title":"Am J Surg Pathol"},{"key":"BF1705224_CR34","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1097\/00043426-199608000-00012","volume":"18","author":"CS Kretschmar","year":"1996","unstructured":"Kretschmar CS, Colbach C, Bhan I, Crombleholme TM . Desmoplastic small round cell tumor: a report of three cases and review of the literature. J Pediatr Hematol Oncol 1996; 18: 293\u2013298.","journal-title":"J Pediatr Hematol Oncol"},{"key":"BF1705224_CR35","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1097\/00043426-200009000-00012","volume":"22","author":"P Kurre","year":"2000","unstructured":"Kurre P, Felgenhauer JL, Miser JS, Patterson K, Hawkins DS . Successful dose-intensive treatment of desmoplastic small round cell tumor in three children. J Pediatr Hematol Oncol 2000; 22: 446\u2013450.","journal-title":"J Pediatr Hematol Oncol"}],"container-title":["Bone Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/1705224","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1705224.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1705224.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T00:13:38Z","timestamp":1648080818000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1705224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11,7]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,1,1]]}},"alternative-id":["BF1705224"],"URL":"https:\/\/doi.org\/10.1038\/sj.bmt.1705224","relation":{},"ISSN":["0268-3369","1476-5365"],"issn-type":[{"value":"0268-3369","type":"print"},{"value":"1476-5365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,11,7]]},"assertion":[{"value":"6 June 2005","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 September 2005","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 September 2005","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 November 2005","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}