{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T20:19:11Z","timestamp":1768249151034,"version":"3.49.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2007,4,16]],"date-time":"2007-04-16T00:00:00Z","timestamp":1176681600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2007,4,16]],"date-time":"2007-04-16T00:00:00Z","timestamp":1176681600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bone Marrow Transplant"],"published-print":{"date-parts":[[2007,6]]},"DOI":"10.1038\/sj.bmt.1705677","type":"journal-article","created":{"date-parts":[[2007,4,16]],"date-time":"2007-04-16T12:09:21Z","timestamp":1176725361000},"page":"775-781","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":136,"title":["Epidemiology of bacteremia and factors associated with multi-drug-resistant gram-negative bacteremia in hematopoietic stem cell transplant recipients"],"prefix":"10.1038","volume":"39","author":[{"given":"A L","family":"Oliveira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"de Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V M H","family":"Carvalho-Dias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M A","family":"Ruiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Silla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P Yurie","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B P","family":"Sim\u00f5es","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Trabasso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Seber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C J","family":"Lotfi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M A","family":"Zanichelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V R","family":"Araujo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Godoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Maiolino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Urakawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C A","family":"Cunha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C A","family":"de Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Pasquini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Nucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2007,4,16]]},"reference":[{"key":"BF1705677_CR1","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1086\/322604","volume":"33","author":"BA Collin","year":"2001","unstructured":"Collin BA, Leather HL, Wingard JR, Ramphal R . Evolution, incidence, and susceptibility of bacterial bloodstream isolates from 519 bone marrow transplant patients. Clin Infect Dis 2001; 33: 947\u2013953.","journal-title":"Clin Infect Dis"},{"key":"BF1705677_CR2","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1086\/374339","volume":"36","author":"H Wisplinghoff","year":"2003","unstructured":"Wisplinghoff H, Seifert H, Wenzel RP, Edmond MB . Current trends in the epidemiology of nosocomial bloodstream infections in patients with hematological malignancies and solid neoplasms in hospitals in the United States. Clin Infect Dis 2003; 36: 1103\u20131110.","journal-title":"Clin Infect Dis"},{"key":"BF1705677_CR3","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1038\/sj.bmt.1701404","volume":"22","author":"E Sparrelid","year":"1998","unstructured":"Sparrelid E, Hagglund H, Remberger M, Ringden O, Lonnqvist B, Ljungman P et al. Bacteraemia during the aplastic phase after allogeneic bone marrow transplantation is associated with early death from invasive fungal infection. Bone Marrow Transplant 1998; 22: 795\u2013800.","journal-title":"Bone Marrow Transplant"},{"key":"BF1705677_CR4","doi-asserted-by":"publisher","first-page":"2413","DOI":"10.1016\/S0959-8049(01)00274-X","volume":"37","author":"R Haupt","year":"2001","unstructured":"Haupt R, Romanengo M, Fears T, Viscoli C, Castagnola E . Incidence of septicaemias and invasive mycoses in children undergoing treatment for solid tumours: a 12-year experience at a single Italian institution. Eur J Cancer 2001; 37: 2413\u20132419.","journal-title":"Eur J Cancer"},{"key":"BF1705677_CR5","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1097\/00001432-200208000-00004","volume":"15","author":"C Viscoli","year":"2002","unstructured":"Viscoli C, Castagnola E . Treatment of febrile neutropenia: what is new? Curr Opin Infect Dis 2002; 15: 377\u2013382.","journal-title":"Curr Opin Infect Dis"},{"key":"BF1705677_CR6","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/S0272-5231(05)70143-X","volume":"20","author":"SK Fridkin","year":"1999","unstructured":"Fridkin SK, Gaynes RP . Antimicrobial resistance in intensive care units. Clin Chest Med 1999; 20: 303\u2013316.","journal-title":"Clin Chest Med"},{"key":"BF1705677_CR7","doi-asserted-by":"publisher","first-page":"S11","DOI":"10.1086\/344654","volume":"36","author":"DM Livermore","year":"2003","unstructured":"Livermore DM . Bacterial resistance: origins, epidemiology, and impact. Clin Infect Dis 2003; 36: S11\u2013S23.","journal-title":"Clin Infect Dis"},{"issue":"Suppl 2","key":"BF1705677_CR8","doi-asserted-by":"publisher","first-page":"S10","DOI":"10.1093\/ajhp\/57.suppl_2.S10","volume":"57","author":"JA Paladino","year":"2000","unstructured":"Paladino JA . Economic justification of antimicrobial management programs: implications of antimicrobial resistance. Am J Health Syst Pharm 2000; 57 (Suppl 2): S10\u2013S12.","journal-title":"Am J Health Syst Pharm"},{"key":"BF1705677_CR9","unstructured":"Garnica M, Oliveira AL, Nouer SA, Nucci M . Resistant Gram-negative bacteremias in hematopoietic stem cell transplant (HSCT) recipients: incidence and outcome. Abstracts of the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy 2004, Book of abstracts, abstract no. K-1446."},{"key":"BF1705677_CR10","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1093\/jac\/dkg416","volume":"52","author":"AC Gales","year":"2003","unstructured":"Gales AC, Menezes LC, Silbert S, Sader HS . Dissemination in distinct Brazilian regions of an epidemic carbapenem-resistant Pseudomonas aeruginosa producing SPM metallo-beta-lactamase. J Antimicrob Chemother 2003; 52: 699\u2013702.","journal-title":"J Antimicrob Chemother"},{"key":"BF1705677_CR11","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1590\/S1413-86702005000300004","volume":"9","author":"C Kiffer","year":"2005","unstructured":"Kiffer C, Hsiung A, Oplustil C, Sampaio J, Sakagami E, Turner P et al. Antimicrobial susceptibility of Gram-negative bacteria in Brazilian hospitals: the MYSTIC Program Brazil 2003. Braz J Infect Dis 2005; 9: 216\u2013224.","journal-title":"Braz J Infect Dis"},{"key":"BF1705677_CR12","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1590\/S1413-86702005000100008","volume":"9","author":"C Mendes","year":"2005","unstructured":"Mendes C, Oplustil C, Sakagami E, Turner P, Kiffer C . Antimicrobial susceptibility in intensive care units: MYSTIC Program Brazil 2002. Braz J Infect Dis 2005; 9: 44\u201351.","journal-title":"Braz J Infect Dis"},{"key":"BF1705677_CR13","unstructured":"National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility testing, 9th Informational Supplement NCCLS 1999 M100-S9."},{"key":"BF1705677_CR14","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1093\/infdis\/161.3.397","volume":"161","author":"Immunocompromised Host Society","year":"1990","unstructured":"Immunocompromised Host Society. The design, analysis, and reporting of clinical trials on the empirical antibiotic management of the neutropenic patient. Report of a consensus panel. J Infect Dis 1990; 161: 397\u2013401.","journal-title":"J Infect Dis"},{"key":"BF1705677_CR15","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1086\/598620","volume":"29","author":"SH Zinner","year":"1999","unstructured":"Zinner SH . Changing epidemiology of infections in patients with neutropenia and cancer: emphasis on gram-positive and resistant bacteria. Clin Infect Dis 1999; 29: 490\u2013494.","journal-title":"Clin Infect Dis"},{"key":"BF1705677_CR16","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1007\/s100960050251","volume":"18","author":"D Buchheidt","year":"1999","unstructured":"Buchheidt D, Hiddemann W, Schiel X, Kremery V, Karthaus M, Donnelly JP et al. European surveillance of infections and risk factors in cancer patients. Eur J Clin Microbiol Infect Dis 1999; 18: 161\u2013163.","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"BF1705677_CR17","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.medmal.2003.10.003","volume":"34","author":"M Elouennass","year":"2004","unstructured":"Elouennass M, Foissaud V, Trueba F, Doghmi K, Malfuson JV, Fagot T et al. A 7-year survey of strains identified in blood cultures in a clinical hematology unit. Med Mal Infect 2004; 34: 62\u201369.","journal-title":"Med Mal Infect"},{"key":"BF1705677_CR18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10096-005-0077-8","volume":"25","author":"E Velasco","year":"2006","unstructured":"Velasco E, Byington R, Martins CA, Schirmer M, Dias LM, Goncalves VM . Comparative study of clinical characteristics of neutropenic and non-neutropenic adult cancer patients with bloodstream infections. Eur J Clin Microbiol Infect Dis 2006; 25: 1\u20137.","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"BF1705677_CR19","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1097\/00006454-199311000-00005","volume":"12","author":"AS Petrilli","year":"1993","unstructured":"Petrilli AS, Melaragno R, Barros KV, Silva AA, Kusano E, Ribeiro RC et al. Fever and neutropenia in children with cancer: a therapeutic approach related to the underlying disease. Pediatr Infect Dis J 1993; 12: 916\u2013921.","journal-title":"Pediatr Infect Dis J"},{"key":"BF1705677_CR20","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1038\/sj.bmt.1703855","volume":"31","author":"A Maiolino","year":"2003","unstructured":"Maiolino A, Biasoli I, Lima J, Portugal AC, Pulcheri W, Nucci M . Engraftment syndrome following autologous hematopoietic stem cell transplantation: definition of diagnostic criteria. Bone Marrow Transplant 2003; 31: 393\u2013397.","journal-title":"Bone Marrow Transplant"},{"key":"BF1705677_CR21","doi-asserted-by":"publisher","first-page":"979","DOI":"10.7326\/0003-4819-142-12_Part_1-200506210-00008","volume":"142","author":"A Gafter-Gvili","year":"2005","unstructured":"Gafter-Gvili A, Fraser A, Paul M, Leibovici L . Meta-analysis: antibiotic prophylaxis reduces mortality in neutropenic patients. Ann Intern Med 2005; 142: 979\u2013995.","journal-title":"Ann Intern Med"},{"key":"BF1705677_CR22","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1016\/S0188-4409(00)00080-1","volume":"31","author":"J Gaytan-Martinez","year":"2000","unstructured":"Gaytan-Martinez J, Mateos-Garcia E, Sanchez-Cortes E, Gonzalez-Llaven J, Casanova-Cardiel LJ, Fuentes-Allen JL . Microbiological findings in febrile neutropenia. Arch Med Res 2000; 31: 388\u2013392.","journal-title":"Arch Med Res"},{"key":"BF1705677_CR23","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1086\/515103","volume":"28","author":"EA Engels","year":"1999","unstructured":"Engels EA, Ellis CA, Supran SE, Schmid CH, Barza M, Schenkein DP et al. Early infection in bone marrow transplantation: quantitative study of clinical factors that affect risk. Clin Infect Dis 1999; 28: 256\u2013266.","journal-title":"Clin Infect Dis"},{"key":"BF1705677_CR24","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1038\/sj.bmt.1703920","volume":"31","author":"M Dettenkofer","year":"2003","unstructured":"Dettenkofer M, Ebner W, Bertz H, Babikir R, Finke J, Frank U et al. Surveillance of nosocomial infections in adult recipients of allogeneic and autologous bone marrow and peripheral blood stem-cell transplantation. Bone Marrow Transplant 2003; 31: 795\u2013801.","journal-title":"Bone Marrow Transplant"},{"key":"BF1705677_CR25","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1007\/S100960100582","volume":"20","author":"A Lang","year":"2001","unstructured":"Lang A, De FG, Meyer R, Aschbacher R, Rizza F, Mayr O et al. Comparison of antimicrobial use and resistance of bacterial isolates in a haematology ward and an intensive care unit. Eur J Clin Microbiol Infect Dis 2001; 20: 657\u2013660.","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"BF1705677_CR26","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1007\/s101560050031","volume":"5","author":"S Spanik","year":"1999","unstructured":"Spanik S, Krupova I, Trupl J, Kunova A, Novotny J, Mateicka F et al. Bacteremia due to multiresistant gram-negative bacilli in neutropenic cancer patients: a case-controlled study. J Infect Chemother 1999; 5: 180\u2013184.","journal-title":"J Infect Chemother"},{"key":"BF1705677_CR27","doi-asserted-by":"publisher","first-page":"3663","DOI":"10.1128\/AAC.49.9.3663-3667.2005","volume":"49","author":"SA Nouer","year":"2005","unstructured":"Nouer SA, Nucci M, de-Oliveira MP, Pellegrino FL, Moreira BM . Risk factors for acquisition of multidrug-resistant Pseudomonas aeruginosa producing SPM metallo-beta-lactamase. Antimicrob Agents Chemother 2005; 49: 3663\u20133667.","journal-title":"Antimicrob Agents Chemother"},{"key":"BF1705677_CR28","doi-asserted-by":"publisher","first-page":"c58","DOI":"10.1159\/000086223","volume":"101","author":"D Marchaim","year":"2005","unstructured":"Marchaim D, Lazarovitch Z, Efrati S, Dishy V, Weissgarten J, Boldur I et al. Serious consequences to the use of cephalosporins as the first line of antimicrobial therapy administered in hemodialysis units. Nephron Clin Pract 2005; 101: c58\u2013c64.","journal-title":"Nephron Clin Pract"},{"key":"BF1705677_CR29","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1086\/502304","volume":"25","author":"SO Lee","year":"2004","unstructured":"Lee SO, Lee ES, Park SY, Kim SY, Seo YH, Cho YK . Reduced use of third-generation cephalosporins decreases the acquisition of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae. Infect Control Hosp Epidemiol 2004; 25: 832\u2013837.","journal-title":"Infect Control Hosp Epidemiol"},{"key":"BF1705677_CR30","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1093\/jac\/dki180","volume":"56","author":"EM Graffunder","year":"2005","unstructured":"Graffunder EM, Preston KE, Evans AM, Venezia RA . Risk factors associated with extended-spectrum beta-lactamase-producing organisms at a tertiary care hospital. J Antimicrob Chemother 2005; 56: 139\u2013145.","journal-title":"J Antimicrob Chemother"},{"key":"BF1705677_CR31","first-page":"1238","volume":"89","author":"A Bacigalupo","year":"2004","unstructured":"Bacigalupo A, Sormani MP, Lamparelli T, Gualandi F, Occhini D, Bregante S et al. Reducing transplant-related mortality after allogeneic hematopoietic stem cell transplantation. Haematologica 2004; 89: 1238\u20131247.","journal-title":"Haematologica"}],"container-title":["Bone Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/1705677.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1705677","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1705677.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T00:22:12Z","timestamp":1648081332000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1705677"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4,16]]},"references-count":31,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2007,6]]}},"alternative-id":["BF1705677"],"URL":"https:\/\/doi.org\/10.1038\/sj.bmt.1705677","relation":{},"ISSN":["0268-3369","1476-5365"],"issn-type":[{"value":"0268-3369","type":"print"},{"value":"1476-5365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,4,16]]},"assertion":[{"value":"12 December 2006","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 February 2007","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 March 2007","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 April 2007","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}