{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T02:42:02Z","timestamp":1761100922420},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2007,8,6]],"date-time":"2007-08-06T00:00:00Z","timestamp":1186358400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2007,8,6]],"date-time":"2007-08-06T00:00:00Z","timestamp":1186358400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bone Marrow Transplant"],"published-print":{"date-parts":[[2007,10]]},"DOI":"10.1038\/sj.bmt.1705794","type":"journal-article","created":{"date-parts":[[2007,8,7]],"date-time":"2007-08-07T09:38:19Z","timestamp":1186479499000},"page":"705-706","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Lymphocyte reconstitution after allogeneic bone marrow transplantation in a previously thymectomized patient\u2014no evidence of extrathymic T-cell maturation"],"prefix":"10.1038","volume":"40","author":[{"given":"S","family":"Giebel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Dziaczkowska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Wysoczanska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Wojnar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Krawczyk-Kulis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Lange","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Holowiecki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2007,8,6]]},"reference":[{"key":"BF1705794_CR1","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1038\/25374","volume":"396","author":"DC Douek","year":"1998","unstructured":"Douek DC, McFarland RD, Keiser PH, Gage EA, Massey JM, Haynes BF et al. Changes in thymic function with age and during the treatment of HIV infection. Nature 1998; 396: 690\u2013695.","journal-title":"Nature"},{"key":"BF1705794_CR2","doi-asserted-by":"publisher","first-page":"1473","DOI":"10.1093\/intimm\/7.9.1473","volume":"7","author":"C Lundqvist","year":"1995","unstructured":"Lundqvist C, Baranov V, Hammarstrom S, Athlin L, Hammarstrom ML . Intra-epithelial lymphocytes: evidence for regional specialization and extrathymic T cell maturation in the human gut epithelium. Int Immunol 1995; 7: 1473.","journal-title":"Int Immunol"},{"key":"BF1705794_CR3","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1002\/eji.1830250502","volume":"25","author":"S Lynch","year":"1995","unstructured":"Lynch S, Kelleher D, McManus R, O'Farrelly C . RAG1 and RAG2 expression in human intestinal epithelium: evidence of extrathymic T cell differentiation. Eur J Immunol 1995; 25: 1143.","journal-title":"Eur J Immunol"},{"key":"BF1705794_CR4","doi-asserted-by":"publisher","first-page":"3359","DOI":"10.4049\/jimmunol.171.7.3359","volume":"171","author":"A Bas","year":"2003","unstructured":"Bas A, Hammarstrom S, Hammarstrom M-L . Extrathymic TCR gene rearrangement in human small intestine: identification of new splice forms of recombination activating gene-1 mRNA with selective tissue expression. J Immunol 2003; 171: 3359\u20133371.","journal-title":"J Immunol"},{"key":"BF1705794_CR5","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.1056\/NEJM200005043421804","volume":"342","author":"DD Patel","year":"2000","unstructured":"Patel DD, Gooding ME, Parrott RE, Curtis KM, Haynes BF, Buckley RH . Thymic function after hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency. N Eng J Med 2000; 342: 1325.","journal-title":"N Eng J Med"},{"key":"BF1705794_CR6","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.1182\/blood.V82.8.2585.2585","volume":"82","author":"CL Mackall","year":"1993","unstructured":"Mackall CL, Granger L, Sheard MA, Cepeda R, Gress RE . T cell regeneration after bone marrow transplantation: differential CD45 isoform expression on thymic-derived versus thymic independent progeny. Blood 1993; 82: 2585\u20132594.","journal-title":"Blood"},{"key":"BF1705794_CR7","doi-asserted-by":"publisher","first-page":"3449","DOI":"10.1182\/blood.V99.9.3449","volume":"99","author":"MD Hazenberg","year":"2002","unstructured":"Hazenberg MD, Otto SA, de Pauw ES, Roelofs H, Fibbe WE, Hamann D et al. T cell receptor excision circle and T cell dynamics after allogeneic stem cell transplantation are related to clinical events. Blood 2002; 99: 3449\u20133452.","journal-title":"Blood"},{"key":"BF1705794_CR8","doi-asserted-by":"publisher","first-page":"2366","DOI":"10.1097\/00007890-200006150-00026","volume":"69","author":"A Heitger","year":"2000","unstructured":"Heitger A, Greinix H, Mannhalter C, Mayerl D, Kern H, Eder J et al. Requirement of residual thymus to restore normal T cell subsets after human allogeneic bone marrow transplantation. Transplantation 2000; 69: 2366\u20132373.","journal-title":"Transplantation"},{"key":"BF1705794_CR9","doi-asserted-by":"crossref","first-page":"3662","DOI":"10.1182\/blood.V90.9.3662","volume":"90","author":"N Watanabe","year":"1997","unstructured":"Watanabe N, De Rosa SC, Cmelak A, Hoppe R, Herzenberg LA, Roederer M . Long-term depletion of naive T cells in patients treated for Hodgkin's disease. Blood 1997; 90: 3662\u20133672.","journal-title":"Blood"},{"key":"BF1705794_CR10","doi-asserted-by":"publisher","first-page":"212","DOI":"10.4049\/jimmunol.167.1.212","volume":"167","author":"JM Faint","year":"2001","unstructured":"Faint JM, Annels NE, Curnow SJ, Shields P, Pilling D, Hislop AD et al. Memory T cells constitute a subset of the human CD8+CD45RA+ pool with distinct phenotypic and migratory characteristics. J Immunol 2001; 167: 212\u2013220.","journal-title":"J Immunol"}],"container-title":["Bone Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/1705794.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1705794","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1705794.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T00:42:34Z","timestamp":1648082554000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1705794"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8,6]]},"references-count":10,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2007,10]]}},"alternative-id":["BF1705794"],"URL":"https:\/\/doi.org\/10.1038\/sj.bmt.1705794","relation":{},"ISSN":["0268-3369","1476-5365"],"issn-type":[{"value":"0268-3369","type":"print"},{"value":"1476-5365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,8,6]]},"assertion":[{"value":"6 August 2007","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}