{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T14:32:24Z","timestamp":1791729144886,"version":"4.3.4"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2005,5,27]],"date-time":"2005-05-27T00:00:00Z","timestamp":1117152000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Death Differ"],"published-print":{"date-parts":[[2005,11]]},"DOI":"10.1038\/sj.cdd.4401675","type":"journal-article","created":{"date-parts":[[2005,5,27]],"date-time":"2005-05-27T09:31:28Z","timestamp":1117186288000},"page":"1407-1416","source":"Crossref","is-referenced-by-count":156,"title":["Cytotoxicity of Bacillus thuringiensis Cry1Ab toxin depends on specific binding of the toxin to the cadherin receptor BT-R1 expressed in insect cells"],"prefix":"10.1038","volume":"12","author":[{"given":"X","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Candas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N B","family":"Griko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Rose-Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"L A","family":"Bulla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2005,5,27]]},"reference":[{"key":"BF4401675_CR1","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1126\/science.276.5313.718","volume":"276","author":"BB Finlay","year":"1997","unstructured":"Finlay BB and Cossart P (1997) Exploitation of mammalian host cell functions by bacterial pathogens. Science 276: 718\u2013725","journal-title":"Science"},{"key":"BF4401675_CR2","doi-asserted-by":"publisher","first-page":"224","DOI":"10.3201\/eid0502.990206","volume":"5","author":"CK Schmitt","year":"1999","unstructured":"Schmitt CK, Meysick KC and O'Brien AD (1999) Bacterial toxins: friends or foes? Emerg. Infect. Dis. 5: 224\u2013234","journal-title":"Emerg. Infect. Dis."},{"key":"BF4401675_CR3","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1038\/35080089","volume":"2","author":"G Schiavo","year":"2001","unstructured":"Schiavo G and van der Goot FG (2001) The bacterial toxin toolkit. Nat. Rev. Mol. Cell Biol. 2: 530\u2013537","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"BF4401675_CR4","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1016\/S0955-0674(98)80069-0","volume":"10","author":"C Montecucco","year":"1998","unstructured":"Montecucco C (1998) Protein toxins and membrane transport. Curr. Opin. Cell Biol. 10: 530\u2013536","journal-title":"Curr. Opin. Cell Biol."},{"key":"BF4401675_CR5","doi-asserted-by":"publisher","first-page":"2209","DOI":"10.1073\/pnas.86.7.2209","volume":"86","author":"RO Blaustein","year":"1989","unstructured":"Blaustein RO, Koehler TM, Collier RJ and Finkelstein A (1989) Anthrax toxin: channel-forming activity of protective antigen in planar phospholipid bilayers. Proc. Natl. Acad. Sci. USA 86: 2209\u20132213","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BF4401675_CR6","doi-asserted-by":"publisher","first-page":"6143","DOI":"10.1074\/jbc.M103939200","volume":"277","author":"O Knapp","year":"2002","unstructured":"Knapp O, Benz R, Gibert M, Marvaud JC and Popoff MR (2002) Interaction of Clostridium perfringens iota-toxin with lipid bilayer membranes. Demonstration of channel formation by the activated binding component Ib and channel block by the enzyme component Ia. J. Biol. Chem. 277: 6143\u20136152","journal-title":"J. Biol. Chem."},{"key":"BF4401675_CR7","doi-asserted-by":"crossref","first-page":"16706","DOI":"10.1016\/S0021-9258(19)89448-6","volume":"269","author":"A Schmid","year":"1994","unstructured":"Schmid A, Benz R, Just I and Aktories K (1994) Interaction of Clostridium botulinum C2 toxin with lipid bilayer membranes. Formation of cation-selective channels and inhibition of channel function by chloroquine. J. Biol. Chem. 269: 16706\u201316711","journal-title":"J. Biol. Chem."},{"key":"BF4401675_CR8","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/BF01869107","volume":"115","author":"HU Wilmsen","year":"1990","unstructured":"Wilmsen HU, Pattus F and Buckley JT (1990) Aerolysin, a hemolysin from Aeromonas hydrophila, forms voltage-gated channels in planar lipid bilayers. J. Membr. Biol. 115: 71\u201381","journal-title":"J. Membr. Biol."},{"key":"BF4401675_CR9","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1016\/S0014-5793(02)03609-8","volume":"531","author":"P Ascenzi","year":"2002","unstructured":"Ascenzi P, Visca P, Ippolito G, Spallarossa A, Bolognesi M and Montecucco C (2002) Anthrax toxin: a tripartite lethal combination. FEBS Lett. 531: 384\u2013388","journal-title":"FEBS Lett."},{"key":"BF4401675_CR10","doi-asserted-by":"publisher","first-page":"1859","DOI":"10.1126\/science.274.5294.1859","volume":"274","author":"L Song","year":"1996","unstructured":"Song L, Hobaugh MR, Shustak C, Cheley S, Bayley H and Gouaux JE (1996) Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore. Science 274: 1859\u20131866","journal-title":"Science"},{"key":"BF4401675_CR11","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1016\/S0092-8674(00)80775-8","volume":"97","author":"RJ Gilbert","year":"1999","unstructured":"Gilbert RJ, Jimenez JL, Chen S, Tickle IJ, Rossjohn J, Parker M, Andrew PW and Saibil HR (1999) Two structural transitions in membrane pore formation by pneumolysin, the pore-forming toxin of Streptococcus pneumoniae. Cell 97: 647\u2013655","journal-title":"Cell"},{"key":"BF4401675_CR12","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/S0014-5793(03)00850-0","volume":"552","author":"G Menestrina","year":"2003","unstructured":"Menestrina G, Dalla SM, Comai M, Coraiola M, Viero G, Werner S, Colin DA, Monteil H and Prevost G (2003) Ion channels and bacterial infection: the case of beta-barrel pore-forming protein toxins of Staphylococcus aureus. FEBS Lett. 552: 54\u201360","journal-title":"FEBS Lett."},{"key":"BF4401675_CR13","doi-asserted-by":"publisher","first-page":"1637","DOI":"10.1016\/S0041-0101(01)00151-9","volume":"39","author":"M Fivaz","year":"2001","unstructured":"Fivaz M, Abrami L, Tsitrin Y and van der Goot FG (2001) Not as simple as just punching a hole. Toxicon 39: 1637\u20131645","journal-title":"Toxicon"},{"key":"BF4401675_CR14","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1046\/j.1365-2958.2000.01865.x","volume":"36","author":"A Valeva","year":"2000","unstructured":"Valeva A, Walev I, Gerber A, Klein J, Palmer M and Bhakdi S (2000) Staphylococcal alpha-toxin: repair of a calcium-impermeable pore in the target cell membrane. Mol. Microbiol. 36: 467\u2013476","journal-title":"Mol. Microbiol."},{"key":"BF4401675_CR15","doi-asserted-by":"publisher","first-page":"10995","DOI":"10.1073\/pnas.0404073101","volume":"101","author":"DL Huffman","year":"2004","unstructured":"Huffman DL, Abrami L, Sasik R, Corbeil J, van der Goot FG and Aroian RV (2004) Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins. Proc. Natl. Acad. Sci. USA 101: 10995\u201311000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BF4401675_CR16","doi-asserted-by":"publisher","first-page":"L207","DOI":"10.1152\/ajplung.00156.2001","volume":"282","author":"F Rose","year":"2002","unstructured":"Rose F, Dahlem G, Guthmann B, Grimminger F, Maus U, Hanze J, Duemmer N, Grandel U, Seeger W and Ghofrani HA (2002) Mediator generation and signaling events in alveolar epithelial cells attacked by S. aureus alpha-toxin.. Am. J. Physiol Lung Cell Mol. Physiol 282: L207\u2013L214","journal-title":"Am. J. Physiol Lung Cell Mol. Physiol"},{"key":"BF4401675_CR17","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1046\/j.1462-5822.1999.00009.x","volume":"1","author":"KL Nelson","year":"1999","unstructured":"Nelson KL, Brodsky RA and Buckley JT (1999) Channels formed by subnanomolar concentrations of the toxin aerolysin trigger apoptosis of T lymphomas. Cell Microbiol. 1: 69\u201374","journal-title":"Cell Microbiol."},{"key":"BF4401675_CR18","doi-asserted-by":"publisher","first-page":"6027","DOI":"10.1128\/jb.177.21.6027-6032.1995","volume":"177","author":"H Agaisse","year":"1995","unstructured":"Agaisse H and Lereclus D (1995) How does Bacillus thuringiensis produce so much insecticidal crystal protein? J. Bacteriol 177: 6027\u20136032","journal-title":"J. Bacteriol"},{"key":"BF4401675_CR19","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1080\/09687680310001625792","volume":"21","author":"T Puntheeranurak","year":"2004","unstructured":"Puntheeranurak T, Uawithya P, Potvin L, Angsuthanasombat C and Schwartz JL (2004) Ion channels formed in planar lipid bilayers by the dipteran-specific Cry4B Bacillus thuringiensis toxin and its alpha1-alpha5 fragment. Mol. Membr. Biol. 21: 67\u201374","journal-title":"Mol. Membr. Biol."},{"key":"BF4401675_CR20","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1016\/S0014-5793(97)00801-6","volume":"412","author":"JL Schwartz","year":"1997","unstructured":"Schwartz JL, Lu YJ, Sohnlein P, Brousseau R, Laprade R, Masson L and Adang MJ (1997) Ion channels formed in planar lipid bilayers by Bacillus thuringiensis toxins in the presence of Manduca sexta midgut receptors. FEBS Lett. 412: 270\u2013276","journal-title":"FEBS Lett."},{"key":"BF4401675_CR21","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/S0014-5793(02)02321-9","volume":"513","author":"I Gomez","year":"2002","unstructured":"Gomez I, Sanchez J, Miranda R, Bravo A and Soberon M (2002) Cadherin-like receptor binding facilitates proteolytic cleavage of helix alpha-1 in domain I and oligomer pre-pore formation of Bacillus thuringiensis Cry1Ab toxin. FEBS Lett. 513: 242\u2013246","journal-title":"FEBS Lett."},{"key":"BF4401675_CR22","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1006\/jmbi.1995.0630","volume":"254","author":"P Grochulski","year":"1995","unstructured":"Grochulski P, Masson L, Borisova S, Pusztai-Carey M, Schwartz JL, Brousseau R and Cygler M (1995) Bacillus thuringiensis CryIA(a) insecticidal toxin: crystal structure and channel formation. J. Mol. Biol. 254: 447\u2013464","journal-title":"J. Mol. Biol."},{"key":"BF4401675_CR23","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1038\/353815a0","volume":"353","author":"JD Li","year":"1991","unstructured":"Li JD, Carroll J and Ellar DJ (1991) Crystal structure of insecticidal delta-endotoxin from Bacillus thuringiensis at 2.5 A resolution. Nature 353: 815\u2013821","journal-title":"Nature"},{"key":"BF4401675_CR24","doi-asserted-by":"publisher","first-page":"12289","DOI":"10.1073\/pnas.95.21.12289","volume":"95","author":"E Gazit","year":"1998","unstructured":"Gazit E, La Rocca P, Sansom MS and Shai Y (1998) The structure and organization within the membrane of the helices composing the pore-forming domain of Bacillus thuringiensis delta-endotoxin are consistent with an \u2018umbrella-like\u2019 structure of the pore. Proc. Natl. Acad. Sci. USA 95: 12289\u201312294","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BF4401675_CR25","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0079-6603(08)60887-9","volume":"60","author":"F Rajamohan","year":"1998","unstructured":"Rajamohan F, Lee MK and Dean DH (1998) Bacillus thuringiensis insecticidal proteins: molecular mode of action. Prog. Nucl. Acid Res. Mol. Biol. 60: 1\u201327","journal-title":"Prog. Nucl. Acid Res. Mol. Biol."},{"key":"BF4401675_CR26","doi-asserted-by":"crossref","first-page":"6103","DOI":"10.1128\/JB.181.19.6103-6107.1999","volume":"181","author":"AS Kumar","year":"1999","unstructured":"Kumar AS and Aronson AI (1999) Analysis of mutations in the pore-forming region essential for insecticidal activity of a Bacillus thuringiensis delta-endotoxin. J. Bacteriol 181: 6103\u20136107","journal-title":"J. Bacteriol"},{"key":"BF4401675_CR27","doi-asserted-by":"publisher","first-page":"6123","DOI":"10.1128\/AEM.70.10.6123-6130.2004","volume":"70","author":"V Vachon","year":"2004","unstructured":"Vachon V, Prefontaine G, Rang C, Coux F, Juteau M, Schwartz JL, Brousseau R, Frutos R, Laprade R and Masson L (2004) Helix 4 mutants of the Bacillus thuringiensis insecticidal toxin Cry1Aa display altered pore-forming abilities. Appl. Environ. Microbiol. 70: 6123\u20136130","journal-title":"Appl. Environ. Microbiol."},{"key":"BF4401675_CR28","doi-asserted-by":"publisher","first-page":"6178","DOI":"10.1021\/bi011572e","volume":"41","author":"V Vachon","year":"2002","unstructured":"Vachon V, Prefontaine G, Coux F, Rang C, Marceau L, Masson L, Brousseau R, Frutos R, Schwartz JL and Laprade R (2002) Role of helix 3 in pore formation by the Bacillus thuringiensis insecticidal toxin Cry1Aa. Biochemistry 41: 6178\u20136184","journal-title":"Biochemistry"},{"key":"BF4401675_CR29","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1128\/AEM.65.2.457-464.1999","volume":"65","author":"K Luo","year":"1999","unstructured":"Luo K, Banks D and Adang MJ (1999) Toxicity, binding, and permeability analyses of four Bacillus thuringiensis cry1 delta-endotoxins using brush border membrane vesicles of Spodoptera exigua and Spodoptera frugiperda. Appl. Environ. Microbiol. 65: 457\u2013464","journal-title":"Appl. Environ. Microbiol."},{"key":"BF4401675_CR30","doi-asserted-by":"publisher","first-page":"5490","DOI":"10.1074\/jbc.270.10.5490","volume":"270","author":"RK Vadlamudi","year":"1995","unstructured":"Vadlamudi RK, Weber E, Ji I, Ji TH and Bulla Jr LA (1995) Cloning and expression of a receptor for an insecticidal toxin of Bacillus thuringiensis. J. Biol. Chem. 270: 5490\u20135494","journal-title":"J. Biol. Chem."},{"key":"BF4401675_CR31","doi-asserted-by":"crossref","first-page":"12334","DOI":"10.1016\/S0021-9258(18)31394-2","volume":"268","author":"RK Vadlamudi","year":"1993","unstructured":"Vadlamudi RK, Ji TH and Bulla Jr LA (1993) A specific binding protein from Manduca sexta for the insecticidal toxin of Bacillus thuringiensis subsp. berliner. J. Biol. Chem. 268: 12334\u201312340","journal-title":"J. Biol. Chem."},{"key":"BF4401675_CR32","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1016\/S0965-1748(02)00040-1","volume":"32","author":"JA Dorsch","year":"2002","unstructured":"Dorsch JA, Candas M, Griko NB, Maaty WS, Midboe EG, Vadlamudi RK and Bulla Jr LA (2002) Cry1A toxins of Bacillus thuringiensis bind specifically to a region adjacent to the membrane-proximal extracellular domain of BT-R(1) in Manduca sexta: involvement of a cadherin in the entomopathogenicity of Bacillus thuringiensis. Insect Biochem. Mol. Biol. 32: 1025\u20131036","journal-title":"Insect Biochem. Mol. Biol."},{"key":"BF4401675_CR33","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1126\/science.1060949","volume":"293","author":"LJ Gahan","year":"2001","unstructured":"Gahan LJ, Gould F and Heckel DG (2001) Identification of a gene associated with Bt resistance in Heliothis virescens. Science 293: 857\u2013860","journal-title":"Science"},{"key":"BF4401675_CR34","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1271\/bbb.62.727","volume":"62","author":"Y Nagamatsu","year":"1998","unstructured":"Nagamatsu Y, Toda S, Koike T, Miyoshi Y, Shigematsu S and Kogure M (1998) Cloning, sequencing, and expression of the Bombyx mori receptor for Bacillus thuringiensis insecticidal CryIA(a) toxin. Biosci. Biotechnol. Biochem. 62: 727\u2013734","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"BF4401675_CR35","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1016\/j.ibmb.2004.08.003","volume":"34","author":"S Morin","year":"2004","unstructured":"Morin S, Henderson S, Fabrick JA, Carriere Y, Dennehy TJ, Brown JK and Tabashnik BE (2004) DNA-based detection of Bt resistance alleles in pink bollworm. Insect Biochem. Mol. Biol. 34: 1225\u20131233","journal-title":"Insect Biochem. Mol. Biol."},{"key":"BF4401675_CR36","first-page":"1148","volume":"10","author":"TR Davis","year":"1992","unstructured":"Davis TR, Trotter KM, Granados RR and Wood HA (1992) Baculovirus expression of alkaline phosphatase as a reporter gene for evaluation of production, glycosylation and secretion. Biotechnology (NY) 10: 1148\u20131150","journal-title":"Biotechnology (NY)"},{"key":"BF4401675_CR37","doi-asserted-by":"publisher","first-page":"55168","DOI":"10.1074\/jbc.M406279200","volume":"279","author":"C Rausell","year":"2004","unstructured":"Rausell C, Pardo-Lopez L, Sanchez J, Munoz-Garay C, Morera C, Soberon M and Bravo A (2004) Unfolding events in the water-soluble monomeric Cry1Ab toxin during transition to oligomeric pre-pore and to membrane inserted pore channel. J. Biol. Chem. 279: 55168\u201355175","journal-title":"J. Biol. Chem."},{"key":"BF4401675_CR38","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1128\/AEM.65.6.2503-2507.1999","volume":"65","author":"AI Aronson","year":"1999","unstructured":"Aronson AI, Geng C and Wu L (1999) Aggregation of Bacillus thuringiensis Cry1A toxins upon binding to target insect larval midgut vesicles. Appl. Environ. Microbiol. 65: 2503\u20132507","journal-title":"Appl. Environ. Microbiol."},{"key":"BF4401675_CR39","doi-asserted-by":"publisher","first-page":"22762","DOI":"10.1074\/jbc.M213209200","volume":"278","author":"A Yamaji-Hasegawa","year":"2003","unstructured":"Yamaji-Hasegawa A, Makino A, Baba T, Senoh Y, Kimura-Suda H, Sato SB, Terada N, Ohno S, Kiyokawa E, Umeda M and Kobayashi T (2003) Oligomerization and pore formation of a sphingomyelin-specific toxin, lysenin. J. Biol. Chem. 278: 22762\u201322770","journal-title":"J. Biol. Chem."},{"key":"BF4401675_CR40","first-page":"15","volume":"257","author":"RK Tweten","year":"2001","unstructured":"Tweten RK, Parker MW and Johnson AE (2001) The cholesterol-dependent cytolysins. Curr. Top. Microbiol. Immunol. 257: 15\u201333","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"BF4401675_CR41","doi-asserted-by":"publisher","first-page":"922","DOI":"10.1126\/science.1104444","volume":"307","author":"JS Griffitts","year":"2005","unstructured":"Griffitts JS, Haslam SM, Yang T, Garczynski SF, Mulloy B, Morris H, Cremer PS, Dell A, Adang MJ and Aroian RV (2005) Glycolipids as receptors for Bacillus thuringiensis crystal toxin. Science 307: 922\u2013925","journal-title":"Science"},{"key":"BF4401675_CR42","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/S1096-4959(03)00054-X","volume":"135","author":"EG Midboe","year":"2003","unstructured":"Midboe EG, Candas M and Bulla Jr LA (2003) Expression of a midgut-specific cadherin BT-R1 during the development of Manduca sexta larva. Comp Biochem. Physiol B Biochem. Mol. Biol. 135: 125\u2013137","journal-title":"Comp Biochem. Physiol B Biochem. Mol. Biol."},{"key":"BF4401675_CR43","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1006\/prep.2001.1421","volume":"22","author":"J Meng","year":"2001","unstructured":"Meng J, Candas M, Keeton TP and Bulla Jr LA (2001) Expression in Spodoptera frugiperda (Sf21) insect cells of BT-R(1), a cadherin-related receptor from Manduca sexta for Bacillus thuringiensis Cry1Ab toxin. Protein Expr. Purif. 22: 141\u2013147","journal-title":"Protein Expr. Purif."},{"key":"BF4401675_CR44","doi-asserted-by":"publisher","first-page":"13717","DOI":"10.1021\/bi026323k","volume":"41","author":"M Candas","year":"2002","unstructured":"Candas M, Francis BR, Griko NB, Midboe EG and Bulla Jr LA (2002) Proteolytic cleavage of the developmentally important cadherin BT-R1 in the midgut epithelium of Manduca sexta. Biochemistry 41: 13717\u201313724","journal-title":"Biochemistry"},{"key":"BF4401675_CR45","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1021\/bi0355692","volume":"43","author":"N Griko","year":"2004","unstructured":"Griko N, Candas M, Zhang X, Junker M and Bulla Jr LA (2004) Selective antagonism to the cadherin BT-R1 interferes with calcium-induced adhesion of epithelial membrane vesicles. Biochemistry 43: 1393\u20131400","journal-title":"Biochemistry"},{"key":"BF4401675_CR46","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1111\/j.1432-1033.1997.00797.x","volume":"245","author":"J Carroll","year":"1997","unstructured":"Carroll J and Ellar DJ (1997) Analysis of the large aqueous pores produced by a Bacillus thuringiensis protein insecticide in Manduca sexta midgut-brush-border-membrane vesicles. Eur. J. Biochem. 245: 797\u2013804","journal-title":"Eur. J. Biochem."},{"key":"BF4401675_CR47","doi-asserted-by":"publisher","first-page":"11887","DOI":"10.1074\/jbc.270.20.11887","volume":"270","author":"L Masson","year":"1995","unstructured":"Masson L, Mazza A, Brousseau R and Tabashnik B (1995) Kinetics of Bacillus thuringiensis toxin binding with brush border membrane vesicles from susceptible and resistant larvae of Plutella xylostella. J. Biol. Chem. 270: 11887\u201311896","journal-title":"J. Biol. Chem."},{"key":"BF4401675_CR48","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/S0168-9525(01)02237-5","volume":"17","author":"RA de Maagd","year":"2001","unstructured":"de Maagd RA, Bravo A and Crickmore N (2001) How Bacillus thuringiensis has evolved specific toxins to colonize the insect world. Trends Genet. 17: 193\u2013199","journal-title":"Trends Genet."},{"key":"BF4401675_CR49","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.bbrc.2004.08.054","volume":"323","author":"H Li","year":"2004","unstructured":"Li H, Gonzalez-Cabrera J, Oppert B, Ferre J, Higgins RA, Buschman LL, Radke GA, Zhu KY and Huang F (2004) Binding analyses of Cry1Ab and Cry1Ac with membrane vesicles from Bacillus thuringiensis-resistant and -susceptible Ostrinia nubilalis. Biochem. Biophys. Res. Commun. 323: 52\u201357","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"BF4401675_CR50","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1007\/s004380050596","volume":"256","author":"SE Franklin","year":"1997","unstructured":"Franklin SE, Young L, Watson D, Cigan A, Meyer T and Bulla Jr LA (1997) Southern analysis of BT-R1, the Manduca sexta gene encoding the receptor for the Cry1Ab toxin of Bacillus thuringiensis. Mol. Gen. Genet. 256: 517\u2013524","journal-title":"Mol. Gen. Genet."}],"container-title":["Cell Death &amp; Differentiation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/4401675.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/4401675","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/4401675.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T00:26:29Z","timestamp":1684369589000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/4401675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,5,27]]},"references-count":50,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["BF4401675"],"URL":"https:\/\/doi.org\/10.1038\/sj.cdd.4401675","relation":{},"ISSN":["1350-9047","1476-5403"],"issn-type":[{"value":"1350-9047","type":"print"},{"value":"1476-5403","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,5,27]]}}}