{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T13:48:32Z","timestamp":1760622512708},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Res"],"published-print":{"date-parts":[[2006,4]]},"DOI":"10.1038\/sj.cr.7310044","type":"journal-article","created":{"date-parts":[[2006,4,15]],"date-time":"2006-04-15T13:04:18Z","timestamp":1145106258000},"page":"337-346","source":"Crossref","is-referenced-by-count":4,"title":["Isolation and characterization of Xenopus laevis homologs of the mouse inv gene and functional analysis of the conserved calmodulin binding sites"],"prefix":"10.1038","volume":"16","author":[{"given":"Yukuto","family":"Yasuhiko","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichiro","family":"Shiokawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshio","family":"Mochizuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Asashima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiko","family":"Yokoyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2006,4,13]]},"reference":[{"key":"BF7310044_CR1","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1006\/scdb.1997.0187","volume":"9","author":"K Kosaki","year":"1998","unstructured":"Kosaki K, Casey B . Genetics of human left\u2013right axis malformations. Semin Cell Dev Biol 1998; 9:89\u201399.","journal-title":"Semin Cell Dev Biol"},{"key":"BF7310044_CR2","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1006\/scdb.1997.0186","volume":"9","author":"DM Supp","year":"1998","unstructured":"Supp DM, Brueckner M, Potter SS . Handed asymmetry in the mouse: understanding how things go right (or left) by studying how they go wrong. Semin Cell Dev Biol 1998; 9:77\u201387.","journal-title":"Semin Cell Dev Biol"},{"key":"BF7310044_CR3","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1016\/S0092-8674(00)81705-5","volume":"95","author":"S Nonaka","year":"1998","unstructured":"Nonaka S, Tanaka Y, Okada Y, et al. Randomization of left\u2013right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell 1998; 95:829\u2013837.","journal-title":"Cell"},{"key":"BF7310044_CR4","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1016\/S1097-2765(00)80197-5","volume":"4","author":"Y Okada","year":"1999","unstructured":"Okada Y, Nonaka S, Tanaka Y, et al. Abnormal nodal flow precedes situs inversus in iv and inv mice. Mol Cell 1999; 4:459\u2013468.","journal-title":"Mol Cell"},{"key":"BF7310044_CR5","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1038\/nature00849","volume":"418","author":"S Nonaka","year":"2002","unstructured":"Nonaka S, Shiratori H, Saijoh Y, Hamada H . Determination of left\u2013right patterning of the mouse embryo by artificial nodal flow. Nature 2002; 418:96\u201399.","journal-title":"Nature"},{"key":"BF7310044_CR6","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1126\/science.8480178","volume":"260","author":"T Yokoyama","year":"1993","unstructured":"Yokoyama T, Copeland NG, Jenkins NA, et al. Reversal of left\u2013right asymmetry: a situs inversus mutation. Science 1993; 260:679\u2013682.","journal-title":"Science"},{"key":"BF7310044_CR7","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1038\/381158a0","volume":"381","author":"LA Lowe","year":"1996","unstructured":"Lowe LA, Supp DM, Sampath K, et al. Conserved left\u2013right asymmetry of nodal expression and alterations in murine situs inversus. Nature 1996; 381:158\u2013161.","journal-title":"Nature"},{"key":"BF7310044_CR8","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1038\/381151a0","volume":"381","author":"C Meno","year":"1996","unstructured":"Meno C, Saijoh Y, Fujii H, et al. Left\u2013right asymmetric expression of the TGF beta-family member lefty in mouse embryos. Nature 1996; 381:151\u2013155.","journal-title":"Nature"},{"key":"BF7310044_CR9","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1016\/j.cell.2005.04.008","volume":"121","author":"Y Okada","year":"2005","unstructured":"Okada Y, Takeda S, Tanaka Y, et al. Mechanism of nodal flow: a conserved symmetry breaking event in left\u2013right axis determination. Cell 2005; 121:633\u2013644.","journal-title":"Cell"},{"key":"BF7310044_CR10","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1038\/26006","volume":"395","author":"T Mochizuki","year":"1998","unstructured":"Mochizuki T, Saijoh Y, Tsuchiya K, et al. Cloning of inv, a gene that controls left\/right asymmetry and kidney development. Nature 1998; 395:177\u2013181.","journal-title":"Nature"},{"key":"BF7310044_CR11","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1038\/2450","volume":"20","author":"D Morgan","year":"1998","unstructured":"Morgan D, Turnpenny L, Goodship J, et al. Inversin, a novel gene in the vertebrate left\u2013right axis pathway, is partially deleted in the inv mouse. Nat Genet 1998; 20:149\u2013156.","journal-title":"Nat Genet"},{"key":"BF7310044_CR12","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1007\/s00439-001-0655-5","volume":"110","author":"P Sch\u00f6n","year":"2002","unstructured":"Sch\u00f6n P, Tsuchiya K, Lenoir D, et al. Identification, genomic organization, chromosomal mapping and mutation analysis of the human INV gene, the ortholog of a murine gene implicated in left\u2013right axis development and biliary atresia. Hum Genet 2002; 110:157\u2013165.","journal-title":"Hum Genet"},{"key":"BF7310044_CR13","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1038\/ng1217","volume":"34","author":"EA Otto","year":"2003","unstructured":"Otto EA, Schermer B, Obara T, et al. Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left\u2013right axis determination. Nat Genet 2003; 34:413\u2013420.","journal-title":"Nat Genet"},{"key":"BF7310044_CR14","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1046\/j.1440-169X.2001.00604.x","volume":"43","author":"Y Yasuhiko","year":"2001","unstructured":"Yasuhiko Y, Imai F, Ookubo K, et al. Calmodulin binds to inv protein: implication for the regulation of inv function. Dev Growth Differ 2001; 43:671\u2013681.","journal-title":"Dev Growth Differ"},{"key":"BF7310044_CR15","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1016\/S0091-679X(08)60307-6","volume":"36","author":"RM Harland","year":"1991","unstructured":"Harland RM . In situ hybridization: an improved whole-mount method for Xenopus embryos. Methods Cell Biol 1991; 36:685\u2013695.","journal-title":"Methods Cell Biol"},{"key":"BF7310044_CR16","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.1101\/gad.8.11.1311","volume":"8","author":"RA Rupp","year":"1994","unstructured":"Rupp RA, Snider L, Weintraub H . Xenopus embryos regulate the nuclear localization of XMyoD. Genes Dev 1994; 8:1311\u20131323.","journal-title":"Genes Dev"},{"key":"BF7310044_CR17","doi-asserted-by":"crossref","first-page":"3719","DOI":"10.1242\/dev.122.12.3719","volume":"122","author":"M Zernicka-Goetz","year":"1996","unstructured":"Zernicka-Goetz M, Pines J, Ryan K, et al. An indelible lineage marker for Xenopus using a mutated green fluorescent protein. Development 1996; 122:3719\u20133724.","journal-title":"Development"},{"key":"BF7310044_CR18","first-page":"675","volume":"42","author":"M Shibata","year":"1998","unstructured":"Shibata M, Shinga J, Yasuhiko Y, et al. Overexpression of S-adenosylmethionine decarboxylase (SAMDC) in early Xenopus embryos induces cell dissociation and inhibits transition from the blastula to gastrula stage. Int J Dev Biol 1998; 42:675\u2013686.","journal-title":"Int J Dev Biol"},{"key":"BF7310044_CR19","unstructured":"Nieuwkoop PD, Faber J . Normal Table of Xenopus laevis (Daudin). New York & London: Garland Publishing Inc 1994:252."},{"key":"BF7310044_CR20","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/0092-8674(86)90762-2","volume":"44","author":"M Kozak","year":"1986","unstructured":"Kozak M . Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 1986; 44:283\u2013292.","journal-title":"Cell"},{"key":"BF7310044_CR21","first-page":"406","volume":"4","author":"N Saitou","year":"1987","unstructured":"Saitou N, Nei M . The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 1987; 4:406\u2013425.","journal-title":"Mol Biol Evol"},{"key":"BF7310044_CR22","first-page":"15","volume-title":"Etiology and Morphogenesis of Congenital heart Disease: Twenty Years of Progress in Genetics and Developmental Biology","author":"T Yokoyama","year":"2000","unstructured":"Yokoyama T, Shirayoshi Y, Murakami T, Nakatsuji N . Expression of the inv gene during development and intracellular localization of the inv protein. In: Takao A, Eds. Etiology and Morphogenesis of Congenital heart Disease: Twenty Years of Progress in Genetics and Developmental Biology. Futura Publishing Company: NY, 2000:15\u201318."},{"key":"BF7310044_CR23","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1146\/annurev.bb.24.060195.000505","volume":"24","author":"A Crivici","year":"1995","unstructured":"Crivici A, Ikura M . Molecular and structural basis of target recognition by calmodulin. Annu Rev Biophys Biomol Struct 1995; 24:85\u2013116.","journal-title":"Annu Rev Biophys Biomol Struct"},{"key":"BF7310044_CR24","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1016\/S0962-8924(00)01800-6","volume":"10","author":"D Chin","year":"2000","unstructured":"Chin D, Means AR . Calmodulin: a prototypical calcium sensor. Trends Cell Biol 2000; 10:322\u2013328.","journal-title":"Trends Cell Biol"},{"key":"BF7310044_CR25","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1152\/physrev.1999.79.3.661","volume":"79","author":"LA Jurado","year":"1999","unstructured":"Jurado LA, Chockalingam PS, Jarrett HW . Apocalmodulin. Physiol Rev 1999; 79:661\u2013682.","journal-title":"Physiol Rev"},{"key":"BF7310044_CR26","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/S0092-8674(03)00511-7","volume":"114","author":"J McGrath","year":"2003","unstructured":"McGrath J, Somlo S, Makova S, et al. Two populations of node monocilia initiate left\u2013right asymmetry in the mouse. Cell 2003; 114:61\u201373.","journal-title":"Cell"},{"key":"BF7310044_CR27","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1038\/nature02190","volume":"427","author":"A Raya","year":"2004","unstructured":"Raya A, Kawakami Y, Rodriguez-Esteban C, et al. Notch activity acts as a sensor for extracellular calcium during vertebrate left\u2013right determination. Nature 2004; 427:121\u2013128.","journal-title":"Nature"}],"container-title":["Cell Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/7310044.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/7310044","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/7310044.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T12:56:41Z","timestamp":1684414601000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/7310044"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["BF7310044"],"URL":"https:\/\/doi.org\/10.1038\/sj.cr.7310044","relation":{},"ISSN":["1001-0602","1748-7838"],"issn-type":[{"value":"1001-0602","type":"print"},{"value":"1748-7838","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,4]]}}}