{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T19:47:47Z","timestamp":1750880867774},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evid Based Dent"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1038\/sj.ebd.6400688","type":"journal-article","created":{"date-parts":[[2009,12,18]],"date-time":"2009-12-18T16:14:34Z","timestamp":1261152874000},"page":"114-115","source":"Crossref","is-referenced-by-count":10,"title":["Vitamin B12 for the treatment of recurrent aphthous stomatitis"],"prefix":"10.1038","volume":"10","author":[{"given":"Marco","family":"Carrozzo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,12,24]]},"reference":[{"key":"BF6400688_CR1","first-page":"58","volume":"9","author":"F Brachmann","year":"1954","unstructured":"Brachmann F . Treatment of chronically recurrent aphthae with vitamin B12. Zahnarztl Welt 1954 9: 58\u201359.","journal-title":"Zahnarztl Welt"},{"key":"BF6400688_CR2","first-page":"381","volume":"27","author":"SZ Burgan","year":"2006","unstructured":"Burgan SZ, Sawair FA, Amarin ZO . Hematologic status in patients with recurrent aphthous stomatitis in Jordan. Saudi Med J 2006; 27: 381\u2013384.","journal-title":"Saudi Med J"},{"key":"BF6400688_CR3","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/j.amjoto.2005.09.022","volume":"27","author":"S Koybasi","year":"2006","unstructured":"Koybasi S, Parlak AH, Serin E, Yilmaz F, Serin D . Recurrent aphthous stomatitis: investigation of possible etiologic factors. Am J Otolaryngol 2006; 27: 229\u2013232.","journal-title":"Am J Otolaryngol"},{"key":"BF6400688_CR4","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1016\/0030-4220(82)90189-X","volume":"54","author":"JA Olson","year":"1982","unstructured":"Olson JA, Feinberg I, Silverman Jr S, Abrams D, Greenspan JS . Serum vitamin B12, folate, and iron levels in recurrent aphthous ulceration. Oral Surg Oral Med Oral Pathol 1982; 54: 517\u2013520.","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"BF6400688_CR5","first-page":"872","volume":"33","author":"K Thongprasom","year":"2002","unstructured":"Thongprasom K, Youngnak P, Aneksuk V . Hematologic abnormalities in recurrent oral ulceration. Southeast Asian J Trop Med Publ Health 2002; 33: 872\u2013877.","journal-title":"Asian J Trop Med Publ Health"},{"key":"BF6400688_CR6","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1136\/bmj.2.5969.490","volume":"2","author":"D Wray","year":"1975","unstructured":"Wray D, Ferguson MM, Mason DK, Hutcheon AW, Dagg JH . Recurrent aphthae: treatment with vitamin B12, folic acid, and iron. Br Med J 1975; 2: 490\u2013493.","journal-title":"Br Med J"},{"key":"BF6400688_CR7","first-page":"14","volume":"51","author":"S Porter","year":"1992","unstructured":"Porter S, Flint S, Scully C, Keith O . Recurrent aphthous stomatitis: the efficacy of replacement therapy in patients with underlying hematinic deficiencies. Ann Dent 1992; 51: 14\u201316.","journal-title":"Ann Dent"},{"key":"BF6400688_CR8","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1097\/MAJ.0b013e31816a05f2","volume":"336","author":"E Gulcan","year":"2008","unstructured":"Gulcan E, Toker S, Hatipoglu H, Gulcan A, Toker A . Cyanocobalamin may be beneficial in the treatment of recurrent aphthous ulcers even when vitamin B12 levels are normal. Am J Med Sci 2008; 336: 379\u2013382.","journal-title":"Am J Med Sci"},{"key":"BF6400688_CR9","first-page":"1984","volume":"58","author":"M Abelin","year":"1961","unstructured":"Abelin M . Treatment of herpes simplex with shock doses of vitamin B12 (Cycobemin) and Iloban. Sven Lakartidn 1961; 58: 1984\u20131990.","journal-title":"Sven Lakartidn"},{"key":"BF6400688_CR10","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1016\/S0140-6736(08)60656-X","volume":"371","author":"AB Krueger","year":"2008","unstructured":"Krueger AB, Stone AA . Assessment of pain: a community-based diary survey in the USA. Lancet 2008; 371: 1519\u20131525.","journal-title":"Lancet"},{"key":"BF6400688_CR11","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1001\/archinte.160.9.1349","volume":"160","author":"K Kaptan","year":"2000","unstructured":"Kaptan K, Beyan C, Ural AU, et al. Helicobacter pylori \u2014 is it a novel causative agent in Vitamin B12 deficiency? Arch Intern Med 2000; 160: 1349\u20131353.","journal-title":"Arch Intern Med"},{"key":"BF6400688_CR12","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1111\/j.1365-4632.2008.03667.x","volume":"47","author":"S Karaca","year":"2008","unstructured":"Karaca S, Seyhan M, Senol M, Harputluoglu MM, Ozcan A . The effect of gastric Helicobacter pylori eradication on recurrent aphthous stomatitis. Int J Dermatol 2008; 47: 615\u2013617.","journal-title":"Int J Dermatol"}],"container-title":["Evidence-Based Dentistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/6400688.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/6400688","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/6400688.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T12:33:07Z","timestamp":1684413187000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/6400688"}},"subtitle":["Question: Are sublingual vitamin B12 tablets effective in reducing the frequency of recurrent aphthous stomatitis episodes?"],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["BF6400688"],"URL":"https:\/\/doi.org\/10.1038\/sj.ebd.6400688","relation":{},"ISSN":["1462-0049","1476-5446"],"issn-type":[{"value":"1462-0049","type":"print"},{"value":"1476-5446","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}