{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T12:09:04Z","timestamp":1783944544181,"version":"3.55.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"S1","license":[{"start":{"date-parts":[[2005,7,28]],"date-time":"2005-07-28T00:00:00Z","timestamp":1122508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2005,7,28]],"date-time":"2005-07-28T00:00:00Z","timestamp":1122508800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Nutr"],"published-print":{"date-parts":[[2005,8,1]]},"DOI":"10.1038\/sj.ejcn.1602172","type":"journal-article","created":{"date-parts":[[2005,7,28]],"date-time":"2005-07-28T21:02:35Z","timestamp":1122584555000},"page":"S31-S39","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Long-term maintenance of weight loss with sibutramine in a GP setting following a specialist guided very-low-calorie diet: a double-blind, placebo-controlled, parallel group study"],"prefix":"10.1038","volume":"59","author":[{"given":"E M H","family":"Mathus-Vliegen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the Balance Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2005,7,28]]},"reference":[{"key":"BF1602172_CR1","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1080\/07315724.1999.10718897","volume":"18","author":"JW Anderson","year":"1999","unstructured":"Anderson JW, Vichitbandra S, Qian W & Kryscio RJ (1999): Long-term weight maintenance after an intensive weight-loss program. J. Am. Coll. Nutr. 18, 620\u2013627.","journal-title":"J. Am. Coll. Nutr."},{"key":"BF1602172_CR2","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/S0002-9343(98)00411-2","volume":"106","author":"M Apfelbaum","year":"1999","unstructured":"Apfelbaum M, Vague P, Ziegler O, Hanotin C, Thomas F & Leutenegger E (1999): Long-term maintenance of weight loss after a very-low-calorie diet: a randomized blinded trial of the efficacy and tolerability of sibutramine. Am. J. Med. 106, 179\u2013184.","journal-title":"Am. J. Med."},{"key":"BF1602172_CR3","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1002\/j.1550-8528.1999.tb00701.x","volume":"7","author":"GA Bray","year":"1999","unstructured":"Bray GA, Blackburn GL, Ferguson JM, Greenway FL, Jain AK, Mendel CM, Mendels J, Ryan DH, Schwartz SL, Scheinbaum ML & Seaton TB (1999): Sibutramine produces dose-related weight loss. Obes. Res. 7, 189\u2013198.","journal-title":"Obes. Res."},{"key":"BF1602172_CR4","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1093\/ajcn\/56.2.320","volume":"56","author":"AM Dattilo","year":"1992","unstructured":"Dattilo AM & Kris-Etherton PM (1992): Effects of weight reduction on blood lipids and lipoproteins: a meta-analysis. Am. J. Clin. Nutr. 56, 320\u2013328.","journal-title":"Am. J. Clin. Nutr."},{"key":"BF1602172_CR5","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/0140-6736(92)91481-M","volume":"340","author":"JS Garrow","year":"1992","unstructured":"Garrow JS (1992): Treatment of obesity. Lancet 340, 409\u2013413.","journal-title":"Lancet"},{"key":"BF1602172_CR6","doi-asserted-by":"publisher","first-page":"2119","DOI":"10.1016\/S0140-6736(00)03491-7","volume":"356","author":"WP James","year":"2000","unstructured":"James WP, Astrup A, Finer N, Hilsted J, Kopelman P, Rossner S, Saris WH & Van Gaal LF (2000): Effect of sibutramine on weight maintenance after weight loss: a randomized trial. Lancet 356, 2119\u20132125.","journal-title":"Lancet"},{"key":"BF1602172_CR7","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1056\/NEJMoa012512","volume":"346","author":"WC Knowler","year":"2002","unstructured":"Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA & Nathan DM (2002): Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N. Engl. J. Med. 346, 393\u2013403.","journal-title":"N. Engl. J. Med."},{"issue":"Suppl 1","key":"BF1602172_CR8","first-page":"S30","volume":"21","author":"ME Lean","year":"1997","unstructured":"Lean ME (1997): Sibutramine\u2014a review of clinical efficacy. Int. J. Obes. Relat. Metab. Disord. 21 (Suppl 1), S30\u2013S36.","journal-title":"Int. J. Obes. Relat. Metab. Disord."},{"key":"BF1602172_CR9","doi-asserted-by":"crossref","unstructured":"National Task Force on the Prevention and Treatment of Obesity and National Institutes of Health (1993): Very low-calorie diets. JAMA 270, 967\u2013974.","DOI":"10.1001\/jama.270.8.967"},{"key":"BF1602172_CR10","doi-asserted-by":"crossref","unstructured":"National Task Force on the Prevention and Treatment of Obesity (1996): Long-term pharmacotherapy in the management of obesity. JAMA 276, 1907\u20131915.","DOI":"10.1001\/jama.276.23.1907"},{"key":"BF1602172_CR11","unstructured":"National Heart, Lung and Blood Institute (1998): Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: the evidence report. NIH publication 98-4083. September 1998."},{"key":"BF1602172_CR12","unstructured":"Royal College of Physicians (1998): Clinical management of overweight and obese patients with particular reference to the use of drugs. RCP, 1998."},{"key":"BF1602172_CR13","unstructured":"Royal College of Physicians of London (2003): Anti-obesity drugs: guidance on appropriate prescribing and management A report of the Nutrition Committee of the Royal College of Physicians of London. RCPL, April 2003."},{"issue":"Suppl 4","key":"BF1602172_CR14","doi-asserted-by":"publisher","first-page":"295S","DOI":"10.1038\/oby.2001.134","volume":"9","author":"WH Saris","year":"2001","unstructured":"Saris WH (2001): Very-low-calorie diets and sustained weight loss. Obes. Res. 9 (Suppl 4), 295S\u2013301S.","journal-title":"Obes. Res."},{"key":"BF1602172_CR15","first-page":"505","volume":"50","author":"IG Smith","year":"2001","unstructured":"Smith IG, Goulder MA & on behalf of the Members of the Sibutramine Clinical Study 1047 Team (2001): Randomized placebo-controlled trial of long-term treatment with sibutramine in mild to moderate obesity. J. Fam. Pract. 50, 505\u2013512.","journal-title":"J. Fam. Pract."},{"key":"BF1602172_CR16","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.1056\/NEJM200105033441801","volume":"344","author":"J Tuomilehto","year":"2001","unstructured":"Tuomilehto J, Lindstrom J, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaaniemi S, Laakso M, Louheranta A, Rastas M, Salminen V & Uusitupa M (2001): Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N. Engl. J. Med. 344, 1343\u20131350.","journal-title":"N. Engl. J. Med."},{"key":"BF1602172_CR17","doi-asserted-by":"publisher","first-page":"1128","DOI":"10.1093\/oxfordjournals.aje.a117386","volume":"141","author":"DF Williamson","year":"1995","unstructured":"Williamson DF, Pamuk E, Thun M, Flanders D, Byers T & Heath C (1995): Prospective study of intentional weight loss and mortality in never-smoking overweight US white women aged 40\u201364 years. Am. J. Epidemiol. 141, 1128\u20131141.","journal-title":"Am. J. Epidemiol."},{"key":"BF1602172_CR18","unstructured":"World Health Organization (1985): Energy and protein requirements Report of a joint FAO\/WHO\/UNU expert consultation. Technical Reports Series 729. Geneva: World Health Organization."},{"key":"BF1602172_CR19","unstructured":"World Health Organization (2000): Obesity: preventing and managing the global epidemic Report of a WHO consultation. WHO Technical Report Series 894. Geneva: WHO."},{"key":"BF1602172_CR20","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1056\/NEJM198104163041602","volume":"304","author":"ML Tuck","year":"1981","unstructured":"Tuck ML, Sowers J, Dornfeld L, Kledzik G & Maxwell M (1981): The effect of weight reduction on blood pressure, plasma renin activity, and plasma aldosterone levels in obese patients. N. Engl. J. Med. 304, 930\u2013933.","journal-title":"N. Engl. J. Med."},{"key":"BF1602172_CR21","doi-asserted-by":"crossref","unstructured":"UK prospective study of therapies of maturity-onset diabetes (1983): I. Effect of diet, sulphonylurea, insulin or biguanide therapy on fasting plasma glucose and body weight over one year. Diabetologia 24, 404\u2013411.","DOI":"10.1007\/BF00257337"},{"key":"BF1602172_CR22","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1001\/jama.286.11.1331","volume":"286","author":"A Wirth","year":"2001","unstructured":"Wirth A & Krause J (2001): Long-term weight loss with sibutramine: a randomized controlled trial. JAMA 286, 1331\u20131339.","journal-title":"JAMA"}],"container-title":["European Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/1602172.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1602172","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1602172.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T21:07:29Z","timestamp":1648156049000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1602172"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,7,28]]},"references-count":22,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2005,8,1]]}},"alternative-id":["BF1602172"],"URL":"https:\/\/doi.org\/10.1038\/sj.ejcn.1602172","relation":{},"ISSN":["0954-3007","1476-5640"],"issn-type":[{"value":"0954-3007","type":"print"},{"value":"1476-5640","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,7,28]]},"assertion":[{"value":"28 July 2005","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}