{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T17:08:12Z","timestamp":1790874492731,"version":"4.1.0"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2004,3,31]],"date-time":"2004-03-31T00:00:00Z","timestamp":1080691200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Hum Genet"],"published-print":{"date-parts":[[2004,7]]},"DOI":"10.1038\/sj.ejhg.5201178","type":"journal-article","created":{"date-parts":[[2004,3,31]],"date-time":"2004-03-31T09:22:06Z","timestamp":1080724926000},"page":"513-520","source":"Crossref","is-referenced-by-count":62,"title":["Features of chromosomal abnormalities in spontaneous abortion cell culture failures detected by interphase FISH analysis"],"prefix":"10.1038","volume":"12","author":[{"given":"Igor N","family":"Lebedev","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadezhda V","family":"Ostroverkhova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatyana V","family":"Nikitina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia N","family":"Sukhanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergey A","family":"Nazarenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2004,3,31]]},"reference":[{"key":"BF5201178_CR1","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1111\/j.1469-1809.1980.tb00955.x","volume":"44","author":"TJ Hassold","year":"1980","unstructured":"Hassold TJ, Chen N, Funkhouser J et al.: A cytogenetic study of 1000 spontaneous abortions. Ann Hum Genet 1980; 44: 151\u2013178.","journal-title":"Ann Hum Genet"},{"key":"BF5201178_CR2","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1002\/tera.1420320218","volume":"32","author":"J Byrne","year":"1985","unstructured":"Byrne J, Warburton D, Kline J, Blanc W, Stein Z : Morphology of early fetal death and their chromosomal characteristics. Teratology 1985; 32: 297\u2013315.","journal-title":"Teratology"},{"key":"BF5201178_CR3","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1139\/g85-083","volume":"27","author":"C Lin","year":"1985","unstructured":"Lin C, De Braekeleer M, Jamro H : Gytogenetic studies in spontaneous abortions: the Calgary experience. Can J Genet Cytol 1985; 27: 565\u2013570.","journal-title":"Can J Genet Cytol"},{"key":"BF5201178_CR4","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1093\/oxfordjournals.humrep.a136623","volume":"2","author":"S Guerneri","year":"1987","unstructured":"Guerneri S, Bettio D, Simoni G, Brambati B, Lanzani A, Fraccaro M : Prevalence and distribution of chromosome abnormalities in a sample of first trimester internal abortions. Hum Reprod 1987; 2: 735\u2013739.","journal-title":"Hum Reprod"},{"key":"BF5201178_CR5","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/0028-2243(92)90257-Y","volume":"46","author":"J Dejmek","year":"1992","unstructured":"Dejmek J, Vojtassak J, Malova J : Cytogenetic analysis of 1508 spontaneous abortions originating from south Slovakia. Eur J Obstet Gynecol Reprod Biol 1992; 46: 129\u2013136.","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"BF5201178_CR6","first-page":"317","volume":"125","author":"CR Be","year":"1997","unstructured":"Be CR, Velasquez PM, Youlton RR : A cytogenetic study in 609 abortions. Rev Med Chile 1997; 125: 317\u2013322.","journal-title":"Rev Med Chile"},{"key":"BF5201178_CR7","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1002\/(SICI)1096-8628(19971031)72:3<297::AID-AJMG9>3.0.CO;2-O","volume":"72","author":"DK Griffin","year":"1997","unstructured":"Griffin DK, Millie EA, Redline RW, Hassold TJ, Zaragoza MV : Cytogenetic analysis of spontaneous abortions: comparison of techniques and assessment of the incidence of confined placental mosaicism. Am J Med Genet 1997; 72: 297\u2013301.","journal-title":"Am J Med Genet"},{"key":"BF5201178_CR8","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/S0074-7696(08)61349-2","volume":"167","author":"DK Griffin","year":"1996","unstructured":"Griffin DK : The incidence, origin and etiology of aneuploidy. Int Rev Cytol 1996; 167: 263\u2013296.","journal-title":"Int Rev Cytol"},{"key":"BF5201178_CR9","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1002\/(SICI)1096-8628(19970110)68:1<98::AID-AJMG20>3.0.CO;2-I","volume":"68","author":"JS Hanna","year":"1997","unstructured":"Hanna JS, Shires P, Matile G : Trisomy 1 in a clinically recognized pregnancy. Am J Med Genet 1997; 68: 98.","journal-title":"Am J Med Genet"},{"key":"BF5201178_CR10","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780199632909.001.0001","volume-title":"Human Cytogenetics. A practical approach","author":"DE Rooney","year":"1992","unstructured":"Rooney DE, Czepulkowski BH : Human Cytogenetics. A practical approach. New York: Oxford University Press; 1992."},{"key":"BF5201178_CR11","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1007\/BF00212016","volume":"93","author":"BL Lomax","year":"1994","unstructured":"Lomax BL, Kalousek DK, Kuchinka BD, Barrett IJ, Harrison KJ, Safavi H : The utilization of interphase cytogenetic analysis for the detection of mosaicism. Hum Genet 1994; 93: 243\u2013247.","journal-title":"Hum Genet"},{"key":"BF5201178_CR12","first-page":"233","volume":"21","author":"S Cure","year":"1974","unstructured":"Cure S, Boue J, Boue A : Growth characteristics of human embryonic cell lines with chromosomal anomalies. Biomedicine 1974; 21: 233\u2013236.","journal-title":"Biomedicine"},{"key":"BF5201178_CR13","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1007\/BF00798676","volume":"99","author":"KN Grinberg","year":"1985","unstructured":"Grinberg KN, Terekhov SM : Chromosome imbalance and the cell proliferative potential in vitro. Bull Exp Biol Med 1985; 99: 191\u2013193.","journal-title":"Bull Exp Biol Med"},{"key":"BF5201178_CR14","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1159\/000015557","volume":"88","author":"MB Qumsiyeh","year":"2000","unstructured":"Qumsiyeh MB, Kim KR, Ahmed MN, Bradford W : Cytogenetics and mechanisms of spontaneous abortions: increased apoptosis and decreased cell proliferation in chromosomally abnormal villi. Cytogenet Cell Genet 2000; 88: 230\u2013235.","journal-title":"Cytogenet Cell Genet"},{"key":"BF5201178_CR15","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/S0140-6736(95)90064-0","volume":"345","author":"WH Persutte","year":"1995","unstructured":"Persutte WH, Lenke RR : Failure of amniotic-fluid cell growth: is it related to fetal aneuploidy? Lancet 1995; 345: 96\u201397.","journal-title":"Lancet"},{"key":"BF5201178_CR16","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1016\/0029-7844(95)00479-3","volume":"87","author":"R Reid","year":"1996","unstructured":"Reid R, Sepulveda W, Kyle PM, Davies G : Amniotic fluid culture failure: clinical significance and association with aneuploidy. Obstet Gynecol 1996; 87: 588\u2013592.","journal-title":"Obstet Gynecol"},{"key":"BF5201178_CR17","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1002\/(SICI)1097-0223(199804)18:4<343::AID-PD273>3.0.CO;2-G","volume":"18","author":"YH Lam","year":"1998","unstructured":"Lam YH, Tang MHY, Sin SY, Ghosh A : Clinical significance of amniotic fluid cell culture failure. Prenat. Diagn 1998; 18: 343\u2013347.","journal-title":"Prenat. Diagn"},{"key":"BF5201178_CR18","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1093\/humrep\/13.4.805","volume":"13","author":"M Daniely","year":"1998","unstructured":"Daniely M, Aviram-Goldring A, Barkai G, Aviram-Goldring A : Detection of chromosomal aberration in fetuses arising from recurrent spontaneous abortion by comparative genomic hybridization. Hum Reprod 1998; 13: 805\u2013809.","journal-title":"Hum Reprod"},{"key":"BF5201178_CR19","doi-asserted-by":"publisher","first-page":"1516","DOI":"10.1086\/302878","volume":"66","author":"BL Lomax","year":"2000","unstructured":"Lomax BL, Tang S, Separovic E et al.: Comparative genomic hybridization in combination with flow cytometry improves results of cytogenetic analysis of spontaneous abortions. Am J Hum Genet 2000; 66: 1516\u20131521.","journal-title":"Am J Hum Genet"},{"key":"BF5201178_CR20","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1038\/sj.ejhg.5200669","volume":"9","author":"B Fritz","year":"2001","unstructured":"Fritz B, Hallermann C, Olert J et al.: Cytogenetic analysis of culture failures by comparative genomic hybridization (CGH)\u2013re-evaluation of chromosome aberration rates in early spontaneous abortions. Eur J Hum Genet 2001; 9: 539\u2013547.","journal-title":"Eur J Hum Genet"},{"key":"BF5201178_CR21","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1007\/s004390050638","volume":"101","author":"KS Reddy","year":"1997","unstructured":"Reddy KS : Double trisomy in spontaneous abortions. Hum Genet 1997; 101: 339\u2013345.","journal-title":"Hum Genet"},{"key":"BF5201178_CR22","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1034\/j.1399-0004.1999.560118.x","volume":"56","author":"KS Reddy","year":"1999","unstructured":"Reddy KS : Triple aneuploidy in spontaneous abortions. Clin Genet 1999; 56: 103\u2013104.","journal-title":"Clin Genet"},{"key":"BF5201178_CR23","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/S0015-0282(16)58448-9","volume":"66","author":"CA Benadiva","year":"1996","unstructured":"Benadiva CA, Kligman I, Munne S : Aneuploidy 16 in human embryos increases significantly with maternal age. Fertil Steril 1996; 66: 248\u2013255.","journal-title":"Fertil Steril"},{"key":"BF5201178_CR24","doi-asserted-by":"publisher","first-page":"1224","DOI":"10.1023\/A:1012544706246","volume":"37","author":"IN Lebedev","year":"2001","unstructured":"Lebedev IN, Nazarenko SA : Tissue-specific placental mosaicism for autosomal trisomies in human spontaneous abortuses: mechanisms of formation and phenotypical effects. Russ J Genet 2001; 37: 1224\u20131237.","journal-title":"Russ J Genet"},{"key":"BF5201178_CR25","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/BF00273852","volume":"75","author":"MC Pellissier","year":"1987","unstructured":"Pellissier MC, Philip N, Voelckel-Baeteman MA, Mattei MG, Mattei JF : Monosomy 21: a new case confirmed by in situ hybridization. Hum Genet 1987; 75: 95\u201396.","journal-title":"Hum Genet"},{"key":"BF5201178_CR26","first-page":"247","volume":"31","author":"B Garzicic","year":"1988","unstructured":"Garzicic B, Guc-Scekic M, Pilic-Radivojevic G, Ignjatovic M, Vilhar N : A case of monosomy 21. Ann Genet 1988; 31: 247\u2013249.","journal-title":"Ann Genet"},{"key":"BF5201178_CR27","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1002\/1096-8628(20001218)95:5<454::AID-AJMG9>3.0.CO;2-O","volume":"95","author":"C Ginsburg","year":"2000","unstructured":"Ginsburg C, Fokstuen S, Schinzel A : The contribution of uniparental disomy to congenital development defects in children born to mothers at advanced childbearing age. Am J Med Genet 2000; 95: 454\u2013460.","journal-title":"Am J Med Genet"},{"key":"BF5201178_CR28","first-page":"762","volume":"11","author":"RW Redline","year":"1998","unstructured":"Redline RW, Hassold T, Zaragoza M : Determinants of villous trophoblastic hyperplasia in spontaneous abortions. Mod Pathol 1998; 11: 762\u2013768.","journal-title":"Mod Pathol"},{"key":"BF5201178_CR29","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1136\/jmg.35.11.924","volume":"35","author":"MV Zaragoza","year":"1998","unstructured":"Zaragoza MV, Millie E, Redline RW, Hassold TJ : Studies of non-disjunction in trisomies 2, 7, 15 and 22: does the parental origin of trisomy influence placental morphology? J Med Genet 1998; 35: 924\u2013931.","journal-title":"J Med Genet"},{"key":"BF5201178_CR30","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1002\/pd.1970070904","volume":"7","author":"MH Bogart","year":"1987","unstructured":"Bogart MH, Pandian MR, Jones OW : Abnormal maternal serum chorionic gonadotropin levels in pregnancies with fetal chromosomal abnormalities. Prenat Diagn 1987; 7: 623\u2013630.","journal-title":"Prenat Diagn"},{"key":"BF5201178_CR31","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1093\/hmg\/3.8.1373","volume":"3","author":"DJ Henderson","year":"1994","unstructured":"Henderson DJ, Sherman LS, Loughna SC, Bennett PR, Moore GE : Early embryonic failure associated with uniparental disomy for human chromosome 21. Hum Mol Genet 1994; 3: 1373\u20131376.","journal-title":"Hum Mol Genet"},{"issue":"Suppl","key":"BF5201178_CR32","first-page":"A280","volume":"57","author":"SK Hendricks","year":"1995","unstructured":"Hendricks SK, Pratt L, Cardwell M, Prentice E, Wu SQ : The increased efficacy of FISH and placental touch preparation in the diagnosis of confined placental mosaicism (CPM). Am J Hum Genet 1995; 57 (Suppl): A280.","journal-title":"Am J Hum Genet"},{"key":"BF5201178_CR33","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1002\/pd.1970150109","volume":"15","author":"JC Harper","year":"1995","unstructured":"Harper JC, Coonen E, Handyside AH, Wintson RM, Hopman AH, Delhanty JD : Mosaicism of autosomes and sex chromosomes in morphologically normal, monospermic preimplantation embryos. Prenat Diagn 1995; 15: 41\u201349.","journal-title":"Prenat Diagn"}],"container-title":["European Journal of Human Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/5201178.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/5201178","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/5201178.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T20:30:47Z","timestamp":1705091447000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/5201178"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3,31]]},"references-count":33,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2004,7]]}},"alternative-id":["BF5201178"],"URL":"https:\/\/doi.org\/10.1038\/sj.ejhg.5201178","relation":{},"ISSN":["1018-4813","1476-5438"],"issn-type":[{"value":"1018-4813","type":"print"},{"value":"1476-5438","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,3,31]]}}}