{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T21:58:11Z","timestamp":1787003891358,"version":"build-2736575974"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2002,8,27]],"date-time":"2002-08-27T00:00:00Z","timestamp":1030406400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eye"],"published-print":{"date-parts":[[2002,9]]},"DOI":"10.1038\/sj.eye.6700150","type":"journal-article","created":{"date-parts":[[2002,9,3]],"date-time":"2002-09-03T15:11:13Z","timestamp":1031065873000},"page":"619-621","source":"Crossref","is-referenced-by-count":69,"title":["Overexpression of p53 tumor suppressor gene in pterygia"],"prefix":"10.1038","volume":"16","author":[{"given":"O","family":"Weinstein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Rosenthal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Zirkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Monos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Lifshitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Argov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2002,8,27]]},"reference":[{"key":"BF6700150_CR1","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1016\/S0161-6420(92)31850-0","volume":"99","author":"FD Mackenzie","year":"1992","unstructured":"Mackenzie FD, Hirsh LW, Battistutta D, Green A . Risk analysis in the development of pterygia. Ophthalmology 1992; 99: 1056\u20131061","journal-title":"Ophthalmology"},{"key":"BF6700150_CR2","doi-asserted-by":"publisher","first-page":"1512","DOI":"10.1016\/S0161-6420(99)90445-1","volume":"106","author":"VA Wong","year":"1999","unstructured":"Wong VA, Law FCH . Use of mitimycin C with conjunctival autograft in pterygium surgery in Asian-Canadians. Opthalmology 1999; 106: 1512\u20131515","journal-title":"Opthalmology"},{"key":"BF6700150_CR3","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1136\/bjo.82.6.661","volume":"82","author":"JC Sanchez-Thorin","year":"1998","unstructured":"Sanchez-Thorin JC, Rocha G, Yelin JB . Meta-analysis on the recurrence rates after bare sclera resection with and without mitimycin C use and conjunctival autograft placement in surgery for primary pterygium. Br J Ophthalmol 1998; 82: 661\u2013665","journal-title":"Br J Ophthalmol"},{"key":"BF6700150_CR4","first-page":"4855","volume":"54","author":"MS Greenblatt","year":"1994","unstructured":"Greenblatt MS, Bennett WP, Hollstein M, Harris CC . Mutation in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 1994; 54: 4855\u20134878","journal-title":"Cancer Res"},{"key":"BF6700150_CR5","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1056\/NEJM199310283291807","volume":"28","author":"CC Harris","year":"1993","unstructured":"Harris CC, Holistein M . Clinical implications of the p53 tumor-suppressor gene. New England J Med 1993; 28: 1318\u20131328","journal-title":"New England J Med"},{"key":"BF6700150_CR6","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/0046-8177(95)90031-4","volume":"26","author":"M Younes","year":"1995","unstructured":"Younes M, Lebovitz RM, Bommer KE et al. P53 accumulation in benign breast biopsy specimens. Hum Pathol 1995; 26: 155\u2013158","journal-title":"Hum Pathol"},{"key":"BF6700150_CR7","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1136\/bjo.81.6.493","volume":"81","author":"DA Spandidos","year":"1997","unstructured":"Spandidos DA, Sourvinos H, Kiaris H, Tsamparlakis J . Microsatellite instability and loss of heterozygosity in human pterygia. Br J Ophthalmol 1997; 81: 493\u2013496","journal-title":"Br J Ophthalmol"},{"key":"BF6700150_CR8","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1016\/S0002-9394(14)70141-2","volume":"123","author":"DT Tam","year":"1997","unstructured":"Tam DT, Lim AS, Goh HS, Smith DR . Abnormal expression of the p53 tumor suppressor gene in the conjunctiva of patients with pterygium. Am J Ophthalmol 1997; 123: 404\u2013405","journal-title":"Am J Ophthalmol"},{"key":"BF6700150_CR9","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1076\/ceyr.16.12.1179.5036","volume":"16","author":"N Dushku","year":"1997","unstructured":"Dushku N, Reid TW . P53 expression in altered limbal basal cells of pigueculae, pterygia, and limbal tumors. Curr Eye Res 1997; 16: 1179\u20131192","journal-title":"Curr Eye Res"},{"key":"BF6700150_CR10","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1177\/112067219800800307","volume":"8","author":"C Onur","year":"1998","unstructured":"Onur C, Orhan D, Orhan M, Dizbay Sak S, Tulunay O, Irkee M . Expression of p53 protein in pterygia. Eur J Ophthalmol 1998; 8: 157\u2013161","journal-title":"Eur J Ophthalmol"},{"key":"BF6700150_CR11","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1016\/S0161-6420(00)00651-5","volume":"108","author":"I Chowers","year":"2001","unstructured":"Chowers I, Pe\u2019er J, Zamir E, Livni N, Ilsar M . Proliferative activity and p53 expression in primary and recurrent pterygia. Ophthalmology 2001; 108: 985\u2013988","journal-title":"Ophthalmology"},{"key":"BF6700150_CR12","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1111\/j.1442-9071.1985.tb00400.x","volume":"13","author":"F Brooth","year":"1985","unstructured":"Brooth F . Heredity in one hundred patients admitted for excision of pterygia. Aust N Z J Ophthalmol 1985; 13: 59\u201361","journal-title":"Aust N Z J Ophthalmol"},{"key":"BF6700150_CR13","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1111\/j.1755-3768.1987.tb07016.x","volume":"65","author":"JD Zhang","year":"1987","unstructured":"Zhang JD . An investigation of aetiology and heredity of pterygium. report of 11 cases in a family. Acta Ophthalmol (Copenh) 1987; 65: 413\u2013416","journal-title":"Acta Ophthalmol (Copenh)"},{"key":"BF6700150_CR14","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1136\/jmg.27.6.392","volume":"27","author":"F Hecht","year":"1990","unstructured":"Hecht F, Shoptaugh MG . Winglets of the eye: dominant transmission of early adult pterygium of the conjunctiva. J Med Genet 1990; 27: 392\u2013394","journal-title":"J Med Genet"}],"container-title":["Eye"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/6700150.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/6700150","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/6700150.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T08:09:59Z","timestamp":1684397399000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/6700150"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,8,27]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2002,9]]}},"alternative-id":["BF6700150"],"URL":"https:\/\/doi.org\/10.1038\/sj.eye.6700150","relation":{},"ISSN":["0950-222X","1476-5454"],"issn-type":[{"value":"0950-222X","type":"print"},{"value":"1476-5454","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,8,27]]}}}