{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T02:15:10Z","timestamp":1785204910706,"version":"3.55.0"},"reference-count":84,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2004,2,27]],"date-time":"2004-02-27T00:00:00Z","timestamp":1077840000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eye"],"published-print":{"date-parts":[[2004,7]]},"DOI":"10.1038\/sj.eye.6701308","type":"journal-article","created":{"date-parts":[[2004,3,5]],"date-time":"2004-03-05T10:23:06Z","timestamp":1078482186000},"page":"663-672","source":"Crossref","is-referenced-by-count":194,"title":["Ophthalmic manifestations of acute leukaemias: the ophthalmologist's role"],"prefix":"10.1038","volume":"18","author":[{"given":"T","family":"Sharma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Grewal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P I","family":"Murray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2004,2,27]]},"reference":[{"key":"BF6701308_CR1","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1034\/j.1600-0420.1998.760614.x","volume":"76","author":"SC Reddy","year":"1998","unstructured":"Reddy SC, Menon BS . A prospective study of ocular manifestations in childhood acute leukaemia. Acta Ophthalmol Scand 1998; 76: 700\u2013703.","journal-title":"Acta Ophthalmol Scand"},{"key":"BF6701308_CR2","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1002\/mpo.2950170212","volume":"17","author":"Curto Mlo","year":"1989","unstructured":"Curto Mlo, Zingone A, Aquaviva A, Bagnulo S, Calculli L, Cristiani L et al. Leukaemic infiltration of the eye: results of therapy in a retrospective multicentric study. Med Pediatr Oncol 1989; 17: 134\u2013139.","journal-title":"Med Pediatr Oncol"},{"key":"BF6701308_CR3","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1136\/bjo.76.11.651","volume":"76","author":"K Ohkoshi","year":"1992","unstructured":"Ohkoshi K, Tsiaras WG . Prognostic importance of ophthalmic manifestations in childhood leukaemia. Br J Ophthalmol 1992; 76: 651\u2013655.","journal-title":"Br J Ophthalmol"},{"key":"BF6701308_CR4","first-page":"2152","volume":"9","author":"E Macintyre","year":"1995","unstructured":"Macintyre E, Flandrin G . Biological classification of acute leukemias: federalization or centralization? Leukemia 1995; 9: 2152\u20132154.","journal-title":"Leukemia"},{"key":"BF6701308_CR5","first-page":"218","volume":"12","author":"CL Willman","year":"1999","unstructured":"Willman CL . Acute leukemias: a paradigm for the integration of new technologies in diagnosis and classification. Mod Pathol 1999; 12: 218\u2013228.","journal-title":"Mod Pathol"},{"key":"BF6701308_CR6","first-page":"1190","volume-title":"System of ophthalmology. Cornea and conjunctiva","author":"S Duke-Elder","year":"1965","unstructured":"Duke-Elder S . System of ophthalmology. Cornea and conjunctiva, Vol V111. CV Mosby: St Louis, 1965; 1190\u20131195."},{"key":"BF6701308_CR7","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1001\/archopht.1961.00960010492010","volume":"66","author":"RA Allen","year":"1961","unstructured":"Allen RA, Straatsma BR . Ocular involvement in leukaemia and allied disorders. Arch Ophthalmol 1961; 66: 490\u2013508.","journal-title":"Arch Ophthalmol"},{"key":"BF6701308_CR8","first-page":"458","volume":"10","author":"M Swartz","year":"1975","unstructured":"Swartz M, Jampol LM . Comma-shaped venular segments of conjunctiva in chronic granulocytic leukaemia. Can J Ophthalmol 1975; 10: 458\u2013461.","journal-title":"Can J Ophthalmol"},{"key":"BF6701308_CR9","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/S0002-9394(14)71651-4","volume":"124","author":"J Cook BE","year":"1997","unstructured":"Cook BE J, Bartley GB . Acute lymphoblastic leukaemia manifesting in an adult as a conjunctival mass. Am J Ophthalmol 1997; 124: 104\u2013105.","journal-title":"Am J Ophthalmol"},{"key":"BF6701308_CR10","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/S0936-6555(05)80018-4","volume":"7","author":"KI Lei","year":"1995","unstructured":"Lei KI, Liew CT, Lam DS, Chan AT, Wickham NW . Acute monoblastic leukaemia with conjunctival tumours. Clint Once (R Cull Radial) 1995; 7: 405\u2013406.","journal-title":"Clint Once (R Cull Radial)"},{"key":"BF6701308_CR11","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1136\/bjo.55.2.133","volume":"55","author":"GN Bhadresa","year":"1971","unstructured":"Bhadresa GN . Changes in the anterior segment as a presenting feature in leukaemia. Br J Ophthalmol 1971; 55: 133\u2013135.","journal-title":"Br J Ophthalmol"},{"key":"BF6701308_CR12","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1055\/s-2008-1045510","volume":"205","author":"CW Spraul","year":"1994","unstructured":"Spraul CW, Lang GE, Lang GK . Corneal ulcer in chronic graft-versus-host disease: treatment with collagen shields. Klin Monatsbl Augenheilkd 1994; 205: 161\u2013166.","journal-title":"Klin Monatsbl Augenheilkd"},{"key":"BF6701308_CR13","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1001\/archopht.1983.01040010585011","volume":"101","author":"DA Jabs","year":"1983","unstructured":"Jabs DA, Hirst LW, Green WR, Tutschka PJ, Santos GW, Beschorner WE . The eye in bone marrow transplantation. II. Histopathology. Arch Ophthalmol 1983; 101: 585\u2013590.","journal-title":"II. Histopathology. Arch Ophthalmol"},{"key":"BF6701308_CR14","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1016\/0002-9394(78)90176-9","volume":"86","author":"BJ Mondino","year":"1978","unstructured":"Mondino BJ, Brown SI, Mondzelewski JP . Peripheral corneal ulcers with herpes zoster ophthalmicus. Am J Ophthalmol 1978; 86: 611\u2013614.","journal-title":"Am J Ophthalmol"},{"key":"BF6701308_CR15","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1016\/0002-9394(79)90243-5","volume":"87","author":"HD Perry","year":"1979","unstructured":"Perry HD, Mallen FJ . Iris involvement in granulocytic sarcoma. Am J Ophthalmol 1979; 87: 530\u2013532.","journal-title":"Am J Ophthalmol"},{"key":"BF6701308_CR16","first-page":"1211","volume":"3","author":"AH Wolintz","year":"1971","unstructured":"Wolintz AH, Goldstein JH, Seligman BR, Rosner F, Wesely AC, Lee SL . Secondary glaucoma in leukaemia. Ann Ophthalmol 1971; 3: 1211\u20131213.","journal-title":"Ann Ophthalmol"},{"key":"BF6701308_CR17","first-page":"1081","volume":"8","author":"PJ Rowan","year":"1976","unstructured":"Rowan PJ, Sloan JB . Iris and Anterior chamber involvement in leukaemia. Ann Ophthalmol 1976; 8: 1081\u20131085.","journal-title":"Ann Ophthalmol"},{"key":"BF6701308_CR18","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1001\/archopht.1966.03850010034009","volume":"76","author":"HA Fonken","year":"1966","unstructured":"Fonken HA, Ellis PP . Leukaemic infiltrates in the iris. Arch Ophthalmol 1966; 76: 32\u201336.","journal-title":"Arch Ophthalmol"},{"key":"BF6701308_CR19","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1136\/bjo.52.10.781","volume":"52","author":"B Martin","year":"1968","unstructured":"Martin B . Infiltration of the iris in chronic lymphatic leukaemia. Br J Ophthalmol 1968; 52: 781\u2013785.","journal-title":"Br J Ophthalmol"},{"key":"BF6701308_CR20","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/S0002-9394(14)71181-X","volume":"119","author":"W Ayliffe","year":"1995","unstructured":"Ayliffe W, Foster CS, Marcoux P, Upton M, Finkelstein M, Legmann A . Relapsing acute myeloid leukaemia manifesting as hypopyon uveitis. Am J Ophthalmol 1995; 119: 361\u2013364.","journal-title":"Am J Ophthalmol"},{"key":"BF6701308_CR21","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1002\/mpo.2950250211","volume":"25","author":"M Jankovic","year":"1995","unstructured":"Jankovic M, Conter V, Pretto G, Placa F, D\u2019Incalci M, Masera G . Isolated bilateral anterior chamber eye relapse in a child with acute lymphoblastic leukaemia. Med Pediatr Oncol 1995; 25: 109\u2013112.","journal-title":"Med Pediatr Oncol"},{"key":"BF6701308_CR22","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1016\/S0140-6736(95)91347-5","volume":"346","author":"H MacLean","year":"1995","unstructured":"MacLean H, Clarke MP, Strong NP, Kernahan J . Primary relapse of acute leukaemia in anterior segment of the eye. Lancet 1995; 346: 500.","journal-title":"Lancet"},{"key":"BF6701308_CR23","doi-asserted-by":"publisher","first-page":"197","DOI":"10.3109\/09273949709116894","volume":"5","author":"M Soylu","year":"1997","unstructured":"Soylu M, Ozdemir G, Anli A . Pediatric uveitis in southern Turkey. Ocul Immunol Inflamm 1997; 5: 197\u2013202.","journal-title":"Ocul Immunol Inflamm"},{"key":"BF6701308_CR24","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/S1695-4033(01)77629-1","volume":"55","author":"C Garrido Colino","year":"2001","unstructured":"Garrido Colino C, Mateos Gonzalez M, Torres Valdivieso M, Lopez Perez J, Melero Moreno C, Vivanco Martinez J . Ocular infiltration in the anterior chamber in a female infant with acute non-lymphoblastic leukaemia. Anales Espanoles de Pediatria 2001; 55: 69\u201372.","journal-title":"Anales Espanoles de Pediatria"},{"key":"BF6701308_CR25","first-page":"316","volume":"16","author":"NM Newman","year":"1972","unstructured":"Newman NM, Smith ME, Gay AJ . An unusual case of leukaemia involving the eye: a clinico-pathological study. Surv Ophthalmol 1972; 16: 316\u2013321.","journal-title":"Surv Ophthalmol"},{"key":"BF6701308_CR26","first-page":"307","volume":"69","author":"CA Burns","year":"1965","unstructured":"Burns CA, Blodi FC, Williamson BK . Acute lymphocytic leukaemia and central serous retinopathy. Trans Am Acad Ophthalmol Otolaryngol 1965; 69: 307\u2013309.","journal-title":"Trans Am Acad Ophthalmol Otolaryngol"},{"key":"BF6701308_CR27","first-page":"467","volume":"9","author":"LE Zimmerman","year":"1964","unstructured":"Zimmerman LE, Thoreson HT . Sudden loss of vision in acute leukaemia. A clinico-pathological report of two unusual cases. Surv Ophthalmol 1964; 9: 467\u2013473.","journal-title":"A clinico-pathological report of two unusual cases. Surv Ophthalmol"},{"key":"BF6701308_CR28","first-page":"1867","volume":"11","author":"JE Hine","year":"1979","unstructured":"Hine JE, KIngham JD . Myelogenous leukaemia and bilateral exudative retinal detachment. Ann Ophthalmol 1979; 11: 1867\u20131872.","journal-title":"Ann Ophthalmol"},{"key":"BF6701308_CR29","first-page":"160","volume-title":"Differential Diagnosis of Intraocular Tumours: A Stereoscopic Presentation","author":"JDM Gass","year":"1974","unstructured":"Gass JDM . Differential Diagnosis of Intraocular Tumours: A Stereoscopic Presentation. CV Mosby: St Louis, 1974, pp 160\u2013176."},{"key":"BF6701308_CR30","first-page":"217","volume":"34","author":"W Alemayehu","year":"1996","unstructured":"Alemayehu W, Shamebo M, Bedri A, Mengistu Z . Ocular manifestations of leukaemia in Ethiopians. Ethiop Med J 1996; 34: 217\u2013224.","journal-title":"Ethiop Med J"},{"key":"BF6701308_CR31","first-page":"290","volume-title":"Textbook of the Fundus of the Eye","author":"AJ Ballantyne","year":"1970","unstructured":"Ballantyne AJ, Michaelson IC . Textbook of the Fundus of the Eye. Williams and Wilkins: Baltimore, 1970; 290\u2013292."},{"key":"BF6701308_CR32","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1001\/archopht.1964.00970020494010","volume":"72","author":"T Kuwabara","year":"1964","unstructured":"Kuwabara T, Aiello L . Leukaemic military nodule in retina. Arch Ophthalmol 1964; 72: 494\u2013497.","journal-title":"Arch Ophthalmol"},{"key":"BF6701308_CR33","doi-asserted-by":"crossref","first-page":"253","DOI":"10.3928\/0191-3913-19950701-13","volume":"32","author":"JD Primack","year":"1995","unstructured":"Primack JD, Smith ME, Tychsen L et al. Retinal detachment in a child as the first sign of leukemic relapse. J Pediatr Ophthalmol Strabismus 1995; 32: 253\u2013256.","journal-title":"J Pediatr Ophthalmol Strabismus"},{"key":"BF6701308_CR34","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1136\/bjo.79.9.863","volume":"79","author":"HD Schworm","year":"1995","unstructured":"Schworm HD, Nasemann JE, Schriever S . Subretinal hypopyon in prolymphocytic leukaemia. Br J Ophthalmol 1995; 79: 863\u2013864.","journal-title":"Br J Ophthalmol"},{"key":"BF6701308_CR35","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/0039-6257(83)90123-6","volume":"27","author":"MC Kincaid","year":"1983","unstructured":"Kincaid MC, Green WR . Ocular and orbital involvement in Leukaemia. Surv Ophthalmol 1983; 27: 211\u2013233.","journal-title":"Surv Ophthalmol"},{"key":"BF6701308_CR36","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/0002-9394(75)90139-7","volume":"80","author":"LM Jampol","year":"1975","unstructured":"Jampol LM, Goldberg MF, Busse B . Peripheral retinal micro aneurysms in chronic leukaemia. Am J Ophthalmol 1975; 80: 242\u2013248.","journal-title":"Am J Ophthalmol"},{"key":"BF6701308_CR37","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1001\/archopht.1972.01000020587017","volume":"87","author":"RN Frank","year":"1972","unstructured":"Frank RN, Ryan Jr SJ . Peripheral retinal neovascularistation with chronic myelogenous leukaemia. Arch Ophthalmol 1972; 87: 585\u2013589.","journal-title":"Arch Ophthalmol"},{"key":"BF6701308_CR38","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1016\/S0002-9394(33)93848-9","volume":"16","author":"AB Reese","year":"1933","unstructured":"Reese AB, Guy L . Exophthalmos in leukaemia. Am J Ophthalmol 1933; 16: 718\u2013720.","journal-title":"Am J Ophthalmol"},{"key":"BF6701308_CR39","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/S0002-9394(14)74911-6","volume":"90","author":"M Swartz","year":"1980","unstructured":"Swartz M, Schumann GB . Acute leukaemic infiltration of the vitreous diagnosed by pars plana aspiration. Am J Ophthalmol 1980; 90: 326\u2013330.","journal-title":"Am J Ophthalmol"},{"key":"BF6701308_CR40","first-page":"180","volume":"24","author":"R Zhioua","year":"2001","unstructured":"Zhioua R, Boussen I, Malek I, Ouertani A . Acute lymphoblastic leukaemia and vitreous infiltration. A case study. J Francais Ophtalmol 2001; 24: 180\u2013182.","journal-title":"J Francais Ophtalmol"},{"key":"BF6701308_CR41","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1212\/WNL.10.9.823","volume":"10","author":"RK Shaw","year":"1960","unstructured":"Shaw RK, Moore EW, Freireich EJ, Thomas LB . Meningeal leukaemia. Neurology 1960; 10: 823\u2013833.","journal-title":"Neurology"},{"key":"BF6701308_CR42","doi-asserted-by":"publisher","first-page":"1744","DOI":"10.1002\/1097-0142(197610)38:4<1744::AID-CNCR2820380449>3.0.CO;2-3","volume":"38","author":"EW Ridgway","year":"1976","unstructured":"Ridgway EW, Jaffe N, Walton DS . Leukemic ophthalmopathy in children. Cancer 1976; 38: 1744\u20131746.","journal-title":"Cancer"},{"key":"BF6701308_CR43","doi-asserted-by":"publisher","first-page":"541","DOI":"10.7326\/0003-4819-79-4-541","volume":"79","author":"DM Dawson","year":"1973","unstructured":"Dawson DM, Rosenthal DS, Moloney WC . Neurologic complications of acute leukaemia in adults: changing rates. Ann Int Med 1973; 79: 541\u2013544.","journal-title":"Ann Int Med"},{"key":"BF6701308_CR44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1182\/blood.V25.1.1.1","volume":"25","author":"CB Hyman","year":"1965","unstructured":"Hyman CB, Bogle JM, Brubaker CA, Williams K, Hammond D . Central nervous system involvement by leukaemia in children. Blood 1965; 25: 1\u201312.","journal-title":"Blood"},{"key":"BF6701308_CR45","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1007\/BF00133423","volume":"3","author":"GC Brown","year":"1981","unstructured":"Brown GC, Shields JA, Augsburger JJ, Serota FT, Koch P . Leukemic optic neuropathy. Int Ophthalmol 1981; 3: 111\u2013116.","journal-title":"Int Ophthalmol"},{"key":"BF6701308_CR46","first-page":"84","volume":"12","author":"AR Rosenthal","year":"1975","unstructured":"Rosenthal AR, Egbert PR, Wilbur JR, Probert JC . Leukemic involvement of optic nerve. J Ped Ophthalmol 1975; 12: 84\u201393.","journal-title":"J Ped Ophthalmol"},{"key":"BF6701308_CR47","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1016\/0002-9394(73)90893-3","volume":"75","author":"W Ellis","year":"1973","unstructured":"Ellis W, Little HL . Leukaemic infiltration of the optic nerve head. Am J Ophthalmol 1973; 75: 867\u2013871.","journal-title":"Am J Ophthalmol"},{"key":"BF6701308_CR48","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1159\/000203970","volume":"94","author":"A Colombini","year":"1995","unstructured":"Colombini A, Barzaghi A, Castagneto M, Bovo G, Rossi MR, Rovelli A et al. Retro-orbital late relapse in a child with leukaemia after allogeneic bone marrow transplantation. Acta Haematol 1995; 94: 44\u201347.","journal-title":"Acta Haematol"},{"key":"BF6701308_CR49","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1016\/S0140-6736(71)92684-5","volume":"1","author":"AO Cavdar","year":"1971","unstructured":"Cavdar AO, Gozdasoglu S, Arcasoy A, Demirag B . Chloroma-like ocular manifestations in Turkish children with acute myelo-monocytic leukaemia. Lancet 1971; 1: 680\u2013682.","journal-title":"Lancet"},{"key":"BF6701308_CR50","first-page":"309","volume-title":"Diseases of the Orbit","author":"FA Jakobiec","year":"1979","unstructured":"Jakobiec FA, Jones IS . Lymphomatous plasmacytic, histiocytic, haematopoietic tumours. In: Jones IS, Jakobiec FA (eds). Diseases of the Orbit. Hagerstown Md, Harper and Row, 1979, pp 309 (see pp 345-348)."},{"key":"BF6701308_CR51","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1001\/archopht.119.3.443","volume":"119","author":"B Esmaeli","year":"2001","unstructured":"Esmaeli B, Medeiros LJ, Myers J, Champlin R, Singh S, Ginsberg L . Orbital mass secondary to precursor T-cell acute lymphoblastic leukemia: a rare presentation. Arch Ophthalmol 2001; 119: 443\u2013446.","journal-title":"Arch Ophthalmol"},{"key":"BF6701308_CR52","first-page":"1193","volume":"40","author":"H Kajimoto","year":"1999","unstructured":"Kajimoto H, Naya M, Hojo M, Hibi S, Imashuku S . Relapse of acute lymphoblastic leukaemia as a retro-orbital mass (review). Jpn J Clin Hematol 1999; 40: 1193\u20131197.","journal-title":"Jpn J Clin Hematol"},{"key":"BF6701308_CR53","first-page":"835","volume":"96","author":"LY Hsu","year":"1997","unstructured":"Hsu LY, Jou JR, Tseng HS, Shiue C, Hou PK, Lin KH . Relapse of acute leukemia in childhood presenting as proptosis due to an orbital mass. J Formos Med Assoc 1997; 96: 835\u2013838.","journal-title":"J Formos Med Assoc"},{"key":"BF6701308_CR54","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1007\/BF02723670","volume":"67","author":"BN Lakhkar","year":"2000","unstructured":"Lakhkar BN, Banavali S, Philip P . Orbital granulocytic sarcoma in acute myelogenous leukaemia. Indian J Pediatr 2000; 67: 234\u2013235.","journal-title":"Indian J Pediatr"},{"key":"BF6701308_CR55","first-page":"1739","volume":"11","author":"CM Cullis","year":"1979","unstructured":"Cullis CM, Hines DR, Bullock JD . Anterior segment ischaemia: classification and description in chronic myeloid leukaemia. Ann Ophthalmol 1979; 11: 1739\u20131744.","journal-title":"Ann Ophthalmol"},{"key":"BF6701308_CR56","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1007\/s002770050276","volume":"74","author":"K Shibata","year":"1997","unstructured":"Shibata K, Shimamoto Y, Nishimura T, Okinami S, Yamada H, Miyahara M . Ocular manifestation in adult T cell leukaemia\/lymphoma. Ann Hematol 1997; 74: 163\u2013168.","journal-title":"Ann Hematol"},{"key":"BF6701308_CR57","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/S0002-9394(98)00363-8","volume":"127","author":"F Yaghouti","year":"1999","unstructured":"Yaghouti F, Nouri M, Mannor GE . Ocular adnexal granulocytic sarcoma as the first sign of acute myelogenous leukaemia relapse. Am J Ophthalmol 1999; 127: 361\u2013363.","journal-title":"Am J Ophthalmol"},{"key":"BF6701308_CR58","first-page":"705","volume-title":"Histopathology of skin","author":"WF Lever","year":"1975","unstructured":"Lever WF . Schaumburg. Histopathology of skin, 5th ed. JB, Lippincott: Philadelphia, 1975, pp 705\u2013707."},{"key":"BF6701308_CR59","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1016\/0002-9394(77)90903-5","volume":"83","author":"DG Cogan","year":"1977","unstructured":"Cogan DG . Immunosuppression and eye disease. Am J Ophthalmol 1977; 83: 777\u2013788.","journal-title":"Am J Ophthalmol"},{"key":"BF6701308_CR60","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1016\/0002-9394(79)90356-8","volume":"87","author":"TA Meredith","year":"1979","unstructured":"Meredith TA, Aaberg TM, Reeser FH . Rhegmatogenous retinal detachment complicating CMV retinitis. Am J Ophthalmol 1979; 87: 793\u2013796.","journal-title":"Am J Ophthalmol"},{"key":"BF6701308_CR61","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1038\/sj.bmt.1701796","volume":"23","author":"RC Walton","year":"1999","unstructured":"Walton RC, Reed KL . Herpes zoster ophthalmicus following bone marrow transplantation in children. Bone Marrow Transplant 1999; 23: 1317\u20131320.","journal-title":"Bone Marrow Transplant"},{"key":"BF6701308_CR62","first-page":"100","volume":"14","author":"RA Al-Rashid","year":"1977","unstructured":"Al-Rashid RA, Cress C . Mumps uveitis complicating the course of leukaemia. J Pediatr Ophthalmol. 1977; 14: 100\u2013102.","journal-title":"J Pediatr Ophthalmol."},{"key":"BF6701308_CR63","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1055\/s-2008-1035134","volume":"211","author":"S Nerkelun","year":"1997","unstructured":"Nerkelun S, Kellermann S, Nenning H . Acute blindness caused by fungal infection in chronic myeloid leukaemia. Klin Manatslbl Augenhertkd 1997; 211: 272\u2013274.","journal-title":"Klin Manatslbl Augenhertkd"},{"key":"BF6701308_CR64","first-page":"1116","volume":"83","author":"A Carta","year":"1998","unstructured":"Carta A, Cesana C . Ocular presentation and successful outcome of invasive sphenoid sinus aspergillosis in acute myelogenous leukaemia. Haematologica 1998; 83: 1116\u20131119.","journal-title":"Haematologica"},{"key":"BF6701308_CR65","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1007\/s002770050325","volume":"75","author":"AA Giagounidis","year":"1997","unstructured":"Giagounidis AA, Meckenstock G, Flacke S, Burk M, Wehmeier A, Aul C et al. Pseudamonas aeruginosa blepharoconjunctivitis during cytoreductive chemotherapy in a woman with acute lymphocytic leukaemia. Ann Hematol 1997; 75: 121\u2013123.","journal-title":"Ann Hematol"},{"key":"BF6701308_CR66","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1067\/mjd.2001.119032","volume":"45","author":"KW Morgan","year":"2001","unstructured":"Morgan KW, Callen JP . Sweet's syndrome in acute myelogenous leukaemia presenting as periorbital cellulitis with an infiltrate of leukemic cells. J Am Acad Dermatol 2001; 45: 590\u2013595.","journal-title":"J Am Acad Dermatol"},{"key":"BF6701308_CR67","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1097\/00006982-200202000-00028","volume":"22","author":"J Yoken","year":"2002","unstructured":"Yoken J, Forbes B, Maguire AM, Prenner JL, Carpentieri D . Microsporidial endophthalmitis in a patient with acute myelogenous leukaemia. Retina 2002; 22: 123\u2013125.","journal-title":"Retina"},{"key":"BF6701308_CR68","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1136\/bmj.1.5794.218","volume":"1","author":"MP Ravindranathan","year":"1972","unstructured":"Ravindranathan MP, Paul VJ, Kuriakose ET . Cataract after busulphan treatment. Br Med J 1972; 1: 218\u2013219.","journal-title":"Br Med J"},{"key":"BF6701308_CR69","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1001\/archopht.1967.00980030711004","volume":"78","author":"DM Albert","year":"1967","unstructured":"Albert DM, Wong VG, Henderson ES . Ocular complications of vincristine therapy. Arch Ophthalmol 1967; 78: 709\u2013713.","journal-title":"Arch Ophthalmol"},{"key":"BF6701308_CR70","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1542\/peds.70.2.288","volume":"70","author":"SB Shurin","year":"1982","unstructured":"Shurin SB, Rekate HL, Annable W . Optic atrophy induced by vincristine. Pediatrics 1982; 70: 288\u2013291.","journal-title":"Pediatrics"},{"key":"BF6701308_CR71","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1016\/0002-9394(81)90240-3","volume":"91","author":"G Hopen","year":"1981","unstructured":"Hopen G, Mondino BJ, Johnson BL, Chervenick PA . Corneal toxicity with systemic cytarabine. Am J Ophthalmol 1981; 91: 500\u2013504.","journal-title":"Am J Ophthalmol"},{"key":"BF6701308_CR72","doi-asserted-by":"publisher","first-page":"7","DOI":"10.2165\/00002018-199005010-00003","volume":"5","author":"J Stentoft","year":"1990","unstructured":"Stentoft J . The toxicity of cytarabine. Drug Saf 1990; 5: 7\u201327.","journal-title":"Drug Saf"},{"key":"BF6701308_CR73","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/S0887-8994(98)00148-9","volume":"20","author":"NL Antunes","year":"1999","unstructured":"Antunes NL, Small TN, George D, Boulad F, Lis E . Posterior leukoencephalopathy syndrome may not be reversible. Pediatr Neurol 1999; 20: 241\u2013243.","journal-title":"Pediatr Neurol"},{"key":"BF6701308_CR74","first-page":"21","volume":"77","author":"K Claes","year":"2000","unstructured":"Claes K, Kestelyn P . Ocular manifestations of graft versus host disease following bone marrow transplantation. Bull Soc Belge Ophtalmol 2000; 77: 21\u201326.","journal-title":"Bull Soc Belge Ophtalmol"},{"key":"BF6701308_CR75","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1055\/s-2008-1045634","volume":"202","author":"B Kasmann","year":"1993","unstructured":"Kasmann B, Ruprecht KW . Ophthalmologic findings in graft versus host disease (GvHD). Klin Monatsbl Augenheilkd 1993; 202: 491\u2013499.","journal-title":"Klin Monatsbl Augenheilkd"},{"key":"BF6701308_CR76","first-page":"1444","volume":"99","author":"P Frisk","year":"2002","unstructured":"Frisk P, Hagberg H, Mandahl A, Soderberg P, Lonnerholme G . Cataract in children after autologous bone marrow transplantation. A common but curable complication. Lakartidningen 2002; 99: 1444\u20131447.","journal-title":"Lakartidningen"},{"key":"BF6701308_CR77","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1182\/blood.V57.2.267.267","volume":"57","author":"HM Shulman","year":"1981","unstructured":"Shulman HM, Sullivan KM, Weiden PL, McDonald GB, Striker GE, Sale GE et al. Chronic graft vs host disease in 52 patients: adverse natural course and successful treatment with combination immunosuppression. Blood 1981; 57: 267\u2013276.","journal-title":"Blood"},{"key":"BF6701308_CR78","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/S0161-6420(99)90023-4","volume":"106","author":"JS Ng","year":"1999","unstructured":"Ng JS, Lam DS, Li CK, Chik KW, Cheng GP, Yuen PM et al. Ocular complications of pediatric bone marrow transplantation. Ophthalmology 1999; 106: 160\u2013164.","journal-title":"Ophthalmology"},{"key":"BF6701308_CR79","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1136\/bjo.79.7.687","volume":"79","author":"AR Webster","year":"1995","unstructured":"Webster AR, Anderson JR, Richard EM, Moore AT . Ischaemic retinopathy occurring in patients receiving bone marrow allografts and campath-1G: a clinicopathological study. Br J Ophthalmol 1995; 79: 687\u2013691.","journal-title":"Br J Ophthalmol"},{"key":"BF6701308_CR80","first-page":"452","volume":"1","author":"JF O\u2019Rourke","year":"1980","unstructured":"O\u2019Rourke JF, O\u2019Connor GR . The eye as a sanctuary in acute lymphoblastic leukaemia. Lancet 1980; 1: 452\u2013453.","journal-title":"Lancet"},{"key":"BF6701308_CR81","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1136\/adc.54.1.73","volume":"54","author":"J Ninane","year":"1979","unstructured":"Ninane J, Taylor D, Day S . Leukaemic hypopyon in acute lymphoblastic leukaemia after interruption of treatment. Arch Dis Child 1979; 54: 73\u201374.","journal-title":"Arch Dis Child"},{"key":"BF6701308_CR82","first-page":"829","volume":"1","author":"G Masera","year":"1977","unstructured":"Masera G, Carnelli V, Uderzo C, Toselli C, Lasagni F, Lambertenghi E . Ocular involvement in leukaemia: Report of three cases. Lancet 1977; 1: 829\u2013831.","journal-title":"Lancet"},{"key":"BF6701308_CR83","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1002\/(SICI)1096-911X(199602)26:2<101::AID-MPO6>3.0.CO;2-P","volume":"26","author":"KH Murray","year":"1996","unstructured":"Murray KH, Paolino F, Goldman JM, Galton DA, Grindle CF . Optic nerve head infiltration in acute leukemia in children: an indication for emergency optic nerve radiation therapy. Med Pediatr Oncol 1996; 26: 101\u2013104.","journal-title":"Med Pediatr Oncol"},{"key":"BF6701308_CR84","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1001\/archopht.1957.00930050597013","volume":"57","author":"JF O\u2019Rourke","year":"1957","unstructured":"O\u2019Rourke JF, O\u2019Connor GR . Unusual ocular involvement in acute leukaemia. Arch Ophthalmol 1957; 57: 585\u2013589.","journal-title":"Arch Ophthalmol"}],"container-title":["Eye"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/6701308.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/6701308","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/6701308.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T12:15:45Z","timestamp":1684412145000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/6701308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,2,27]]},"references-count":84,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2004,7]]}},"alternative-id":["BF6701308"],"URL":"https:\/\/doi.org\/10.1038\/sj.eye.6701308","relation":{},"ISSN":["0950-222X","1476-5454"],"issn-type":[{"value":"0950-222X","type":"print"},{"value":"1476-5454","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,2,27]]}}}