{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T04:53:29Z","timestamp":1761540809149},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2007,12,14]],"date-time":"2007-12-14T00:00:00Z","timestamp":1197590400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eye"],"published-print":{"date-parts":[[2008,7]]},"DOI":"10.1038\/sj.eye.6703062","type":"journal-article","created":{"date-parts":[[2007,12,14]],"date-time":"2007-12-14T16:58:06Z","timestamp":1197651486000},"page":"969-974","source":"Crossref","is-referenced-by-count":11,"title":["Serum PON1 arylesterase activity in relation to hyperhomocysteinaemia and oxidative stress in young adult central retinal venous occlusion patients"],"prefix":"10.1038","volume":"22","author":[{"given":"N","family":"Angayarkanni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Barathi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Seethalakshmi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Punitham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Sivaramakrishna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Suganeswari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Tarun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2007,12,14]]},"reference":[{"issue":"1","key":"BF6703062_CR1","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1177\/000331970605700102","volume":"57","author":"MB Kazemi","year":"2006","unstructured":"Kazemi MB, Eshraghian K, Omrani GR, Lankarani KB, Hosseini E . Homocysteine level and coronary artery disease. Angiology 2006; 57 (1): 9\u201314.","journal-title":"Angiology"},{"key":"BF6703062_CR2","doi-asserted-by":"publisher","first-page":"377S","DOI":"10.1093\/jn\/130.2.377S","volume":"30","author":"H Jakubowski","year":"2000","unstructured":"Jakubowski H . Homocysteine thiolactone: metabolic origin and protein homocysteinylation in humans. J Nutr 2000; 30: 377S\u2013381S.","journal-title":"J Nutr"},{"key":"BF6703062_CR3","first-page":"392","volume":"59","author":"J Beltowski","year":"2005","unstructured":"Beltowski J . Protein homocysteinylation: a new mechanism of atherogenesis? Postepy Hig Med Dosw (online) 2005; 59: 392\u2013404.","journal-title":"Postepy Hig Med Dosw (online)"},{"issue":"10","key":"BF6703062_CR4","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1515\/CCLM.2005.177","volume":"43","author":"H Jakubowski","year":"2005","unstructured":"Jakubowski H . Anti-N-homocysteinylated protein autoantibodies and cardiovascular disease. Clin Chem Lab Med 2005; 43 (10): 1011\u20131014.","journal-title":"Clin Chem Lab Med"},{"issue":"4","key":"BF6703062_CR5","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1016\/j.preteyeres.2004.12.001","volume":"24","author":"SS Hayreh","year":"2005","unstructured":"Hayreh SS . Prevalent misconceptions about acute retinal vascular occlusive disorders. Prog Retin Eye Res 2005; 24 (4): 493\u2013519.","journal-title":"Prog Retin Eye Res"},{"key":"BF6703062_CR6","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1097\/00006982-200601000-00011","volume":"26","author":"R Lattanzio","year":"2006","unstructured":"Lattanzio R, Sampirtro F, Ramonia A, Fattorini A, Brancato R . Moderate hyperhomocysteinemia and early-onset central retinal vein occlusion. Retina 2006; 26: 65\u201370.","journal-title":"Retina"},{"key":"BF6703062_CR7","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1159\/000076144","volume":"218","author":"C Yildirim","year":"2004","unstructured":"Yildirim C, Yayali V, Tatlipinar S, Kaptanoglu B, Akpinar S . Hyperhomocysteinemia: a risk factor for retinal vein occlusion. Ophthalmologica 2004; 218: 102\u2013106.","journal-title":"Ophthalmologica"},{"key":"BF6703062_CR8","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1076\/soph.18.3.154.29809","volume":"18","author":"MB Parodi","year":"2003","unstructured":"Parodi MB, Di Crecchio L . Hyperhomocysteinemia in central retinal vein occlusion in young adults. Semin Ophthalmol 2003; 18: 154\u2013159.","journal-title":"Semin Ophthalmol"},{"key":"BF6703062_CR9","doi-asserted-by":"publisher","first-page":"1441","DOI":"10.1167\/iovs.06-0905","volume":"48","author":"N Angayarkanni","year":"2007","unstructured":"Angayarkanni N, Barathi S, Coral K, Punitham R, Ramakrishnan S, Tarun S et al. Hyperhomocysteinemia and low methionine stress are risk factors for Central Retinal Venous Occlusion in an Indian population. Invest Ophthalmol Vis Sci 2007; 48: 1441\u20131446.","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"8","key":"BF6703062_CR10","doi-asserted-by":"publisher","first-page":"1581","DOI":"10.1172\/JCI1649","volume":"101","author":"M Aviram","year":"1998","unstructured":"Aviram M, Rosenblat M, Bisgaier CL, Newton RS, Primo-Parmo SL, La Du BN . Paraoxonase inhibits high-density lipoprotein oxidation and preserves its function. A possible peroxidative role for paraoxonase. J Clin Invest 1998; 101 (8): 1581\u20131590.","journal-title":"J Clin Invest"},{"issue":"5","key":"BF6703062_CR11","first-page":"4","volume":"52","author":"TB Domaga\u0142a","year":"2006","unstructured":"Domaga\u0142a TB, \u0141acinski M, Trzeciak WH, Mackness B . The correlation of homocysteine-thiolactonase activity of the paraoxonase (PON1) protein with coronary heart disease status. Cell Mol Biol 2006; 52 (5): 4\u201310.","journal-title":"Cell Mol Biol"},{"issue":"4","key":"BF6703062_CR12","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1161\/01.ATV.21.4.473","volume":"21","author":"PN Durrington","year":"2001","unstructured":"Durrington PN, Mackness B, Mackness MI . Paraoxonase and atherosclerosis. Arterioscler Thromb Vasc Biol 2001; 21 (4): 473\u2013480.","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"BF6703062_CR13","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.bbapap.2004.08.002","volume":"1702","author":"DT Yeunga","year":"2004","unstructured":"Yeunga DT, Josseb D, Nicholsona JD, Khanalc A, McAndrewc CW, Bahnsonc BJ et al. Structure\/function analyses of human serum paraoxonase (HuPON1) mutants designed from a DFPase-like homology model. Biochim Biophys Acta 2004; 1702: 67\u201377.","journal-title":"Biochim Biophys Acta"},{"key":"BF6703062_CR14","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/0021-9150(93)90183-U","volume":"104","author":"MI Mackness","year":"1993","unstructured":"Mackness MI, Arrol S, Abbott C, Durrington PN . Protection of low-density lipoprotein against oxidative modification by high-density lipoprotein associated paraoxonase. Atherosclerosis 1993; 104: 129\u2013135.","journal-title":"Atherosclerosis"},{"key":"BF6703062_CR15","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1159\/000089269","volume":"220","author":"G Baskol","year":"2006","unstructured":"Baskol G, Karakucuk S, Oner AO, Baskol M, Kocer D, Mirza E et al. Serum paraoxonase 1 activity and lipid peroxidation levels in patients with age-related macular degeneration. Ophthalmologica 2006; 220: 12\u201316.","journal-title":"Ophthalmologica"},{"issue":"1","key":"BF6703062_CR16","first-page":"100","volume":"19","author":"KN Gan","year":"1991","unstructured":"Gan KN, Smolen A, Eckerson HW, La Du BN . Purification of human serum paraoxonase\/arylesterase. Evidence for one esterase catalyzing both activities. Drug Metab Dispos 1991; 19 (1): 100\u2013106.","journal-title":"Drug Metab Dispos"},{"issue":"4","key":"BF6703062_CR17","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1631\/jzus.2007.B0237","volume":"8","author":"F Liao","year":"2007","unstructured":"Liao F, Zhu X-Y, Wang Y-M, Zhao Y-S, Zhu L-P, Zuo Y-P . Correlation of serum arylesterase activity on phenylacetate estimated by the integrated method to common classical biochemical indexes of liver damage. J Zhejiang Univ Sci B 2007; 8 (4): 237\u2013241.","journal-title":"J Zhejiang Univ Sci B"},{"key":"BF6703062_CR18","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1194\/jlr.M200432-JLR200","volume":"44","author":"VG Cabana","year":"2003","unstructured":"Cabana VG, Reardon CA, Feng N, Neath S, Lukens J, Getz GS . Serum paraoxonase: effect of apolipoprotein composition of HDL and the acute phase response. J Lipid Res 2003; 44: 780\u2013792.","journal-title":"J Lipid Res"},{"issue":"1","key":"BF6703062_CR19","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/0006-291X(87)91297-6","volume":"145","author":"TP Devasagayam","year":"1987","unstructured":"Devasagayam TP, Tarachand U . Decrease in lipid peroxidation in the rat kidney during gestation. Biochem Biophys Res Commun 1987; 145 (1): 134\u2013138.","journal-title":"Biochem Biophys Res Commun"},{"key":"BF6703062_CR20","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/0009-8981(86)90247-0","volume":"155","author":"A Ledwozyw","year":"1986","unstructured":"Ledwozyw A, Michalak J, Stepie\u0144 A, Kadziolka A . The relationship between plasma triglycerides, cholesterol, total lipids and lipid peroxidation products during human atherosclerosis. Clin Chim Acta 1986; 155: 275\u2013284.","journal-title":"Clin Chim Acta"},{"key":"BF6703062_CR21","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1194\/jlr.M400511-JLR200","volume":"46","author":"DI Draganov","year":"2005","unstructured":"Draganov DI, Teiber JF, Speelman A, Osawa Y, Sunahara R, La Du BN . Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities. J Lipid Res 2005; 46: 1239\u20131247.","journal-title":"J Lipid Res"},{"key":"BF6703062_CR22","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1194\/jlr.M400052-JLR200","volume":"46","author":"TM van Himbergen","year":"2005","unstructured":"van Himbergen TM, Roest M, de Graaf J, Jansen EH, Jansen M, Hattori H et al. Indications that paraoxonase-1 contributes to plasma high density lipoprotein levels in familial hypercholesterolemia. J Lipid Res 2005; 46: 445\u2013451.","journal-title":"J Lipid Res"},{"issue":"6","key":"BF6703062_CR23","doi-asserted-by":"publisher","first-page":"3957","DOI":"10.1074\/jbc.275.6.3957","volume":"275","author":"H Jakubowski","year":"2000","unstructured":"Jakubowski H . Calcium-dependent human serum homocysteine thiolactone hydrolase. A protective mechanism against protein N-homocysteinylation. J Biol Chem 2000; 275 (6): 3957\u20133962.","journal-title":"J Biol Chem"},{"key":"BF6703062_CR24","doi-asserted-by":"publisher","first-page":"2244","DOI":"10.1016\/j.lfs.2005.09.040","volume":"78","author":"SP Pasca","year":"2006","unstructured":"Pasca SP, Nemes B, Vlase L, Gagyi CE, Dronca E, Miu AC et al. High levels of homocysteine and low serum paraoxonase 1 arylesterase activity in children with autism. Life Sci 2006; 78: 2244\u20132248.","journal-title":"Life Sci"},{"key":"BF6703062_CR25","doi-asserted-by":"publisher","first-page":"1246","DOI":"10.1007\/s00417-005-0191-4","volume":"244","author":"W Goa","year":"2006","unstructured":"Goa W, Wang YS, Zhang P, Wang HY . Hyperhomocyeinemia and low plasma folate as risk factor for CRVO, Case control study in Chinese population. Grafes Arch Clin Exp Opthalmol 2006; 244: 1246\u20131249.","journal-title":"Grafes Arch Clin Exp Opthalmol"},{"issue":"10","key":"BF6703062_CR26","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.1136\/bjo.2004.043398","volume":"88","author":"S Karakucuk","year":"2004","unstructured":"Karakucuk S, Baskol G, Oner AO, Baskol M, Miza E, Ustdal M . Serum paraoxonase activity is decreased in the active stage of Behcet's disease. Br J Ophthalmol 2004; 88 (10): 1256\u20131258.","journal-title":"Br J Ophthalmol"},{"issue":"9\u201310","key":"BF6703062_CR27","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/j.clinbiochem.2007.03.015","volume":"40","author":"Z Hashim","year":"2007","unstructured":"Hashim Z, Zarina S . Assessment of paraoxonase activity and lipid peroxidation levels in diabetic and senile subjects suffering from cataract. Clin Biochem 2007; 40 (9\u201310): 705\u2013709.","journal-title":"Clin Biochem"},{"issue":"8","key":"BF6703062_CR28","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1016\/j.clinbiochem.2006.05.010","volume":"39","author":"M Kerkeni","year":"2006","unstructured":"Kerkeni M, Addad F, Chauffert M, Chuniaud L, Miled A, Trivin F et al. Hyperhomocysteinemia, paraoxonase activity and risk of coronary artery disease. Clin Biochem 2006; 39 (8): 821\u2013825.","journal-title":"Clin Biochem"},{"key":"BF6703062_CR29","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1136\/bjo.86.7.774","volume":"86","author":"SC Martin","year":"2002","unstructured":"Martin SC, Butcher A, Martin N, Farmer J, Dobson PM, Bartlett WA et al. Cardiovascular risk assessment in patients with retinal vein occlusion. Br J Ophthalmol 2002; 86: 774\u2013776.","journal-title":"Br J Ophthalmol"},{"issue":"3","key":"BF6703062_CR30","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1055\/s-2000-8101","volume":"26","author":"R Clarke","year":"2000","unstructured":"Clarke R, Armitage J . Vitamin supplements and cardiovascular risk: review of the randomized trials of homocysteine-lowering vitamin supplements. Semin Thromb Hemost 2000; 26 (3): 341\u2013348.","journal-title":"Semin Thromb Hemost"},{"issue":"2","key":"BF6703062_CR31","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.abb.2006.06.012","volume":"452","author":"MS Calla","year":"2006","unstructured":"Calla MS, Lynch SM . Vitamin C preserves the cardio-protective paraoxonase activity of high-density lipoprotein during oxidant stress. Arch Biochem Biophy 2006; 452 (2): 129\u2013137.","journal-title":"Arch Biochem Biophy"},{"issue":"4","key":"BF6703062_CR32","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1042\/cs0910449","volume":"91","author":"R Abu-Amsha","year":"1996","unstructured":"Abu-Amsha R, Croft KD, Puddey IB, Proudfood JM, Beilin LJ . Phenolic content of various beverages determines the extent of inhibition of human serum and low-density lipoprotein oxidation in vitro: identification and mechanism of action of some cinnamic acid derivatives from red wine. Clin Sci 1996; 91 (4): 449\u2013458.","journal-title":"Clin Sci"}],"container-title":["Eye"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/6703062.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/6703062","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/6703062.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T12:31:58Z","timestamp":1684413118000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/6703062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,12,14]]},"references-count":32,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2008,7]]}},"alternative-id":["BF6703062"],"URL":"https:\/\/doi.org\/10.1038\/sj.eye.6703062","relation":{},"ISSN":["0950-222X","1476-5454"],"issn-type":[{"value":"0950-222X","type":"print"},{"value":"1476-5454","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,12,14]]}}}