{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T22:07:05Z","timestamp":1772575625489,"version":"3.50.1"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2001,12,1]],"date-time":"2001-12-01T00:00:00Z","timestamp":1007164800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2001,12,1]],"date-time":"2001-12-01T00:00:00Z","timestamp":1007164800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Genes Immun"],"published-print":{"date-parts":[[2001,12,1]]},"DOI":"10.1038\/sj.gene.6363803","type":"journal-article","created":{"date-parts":[[2002,9,18]],"date-time":"2002-09-18T16:27:00Z","timestamp":1032366420000},"page":"433-441","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Epstein\u2013Barr virus latent membrane protein-1 activates CD25 expression in lymphoma cells involving the NF\u03baB pathway"],"prefix":"10.1038","volume":"2","author":[{"given":"M","family":"Vockerodt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Tesch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Kube","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2001,12,4]]},"reference":[{"key":"BF6363803_CR1","first-page":"pp\u2009:2397","volume-title":"Fields Virology","author":"AB Rickinson","year":"1996","unstructured":"Rickinson AB, Kieff E Epstein Barr virus. In: Fields BN, Knipe DM, Howley PM (eds) Fields Virology vol. 2 (edn 3) Lippincott-Raven: Philadelphia 1996 pp\u2009:2397\u20132446"},{"key":"BF6363803_CR2","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1128\/jvi.64.5.2309-2318.1990","volume":"64","author":"F Wang","year":"1990","unstructured":"Wang F, Gregory C, Sample C et al Epstein\u2013Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23 J Virol 1990 64 2309\u20132318","journal-title":"J Virol"},{"key":"BF6363803_CR3","doi-asserted-by":"publisher","first-page":"9150","DOI":"10.1073\/pnas.90.19.9150","volume":"90","author":"KM Kaye","year":"1993","unstructured":"Kaye KM, Izumi KM, Kieff E Epstein\u2013Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformation Proc Natl Acad Sci USA 1993 90 9150\u20139154","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF6363803_CR4","doi-asserted-by":"publisher","first-page":"11963","DOI":"10.1073\/pnas.95.20.11963","volume":"95","author":"W Kulwichit","year":"1998","unstructured":"Kulwichit W, Edwards RH, Davenport EM, Baskar JF, Godfrey V, Raab-Traub N Expression of the Epstein\u2013Barr virus latent membrane protein 1 induces B cell lymphoma in transgenic mice Proc Natl Acad Sci USA 1998 95 11963\u201311968","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF6363803_CR5","doi-asserted-by":"publisher","first-page":"16085","DOI":"10.1074\/jbc.274.23.16085","volume":"274","author":"AG Eliopoulos","year":"1999","unstructured":"Eliopoulos AG, Gallagher NJ, Blake SMS, Dawson CW, Young LS Activation of the p38 mitogen-activated protein kinase pathway by Epstein\u2013Barr virus-encoded latent membrane protein 1 coregulates interleukin-6 and interleukin-8 production J Biol Chem 1999 274 16085\u201316096","journal-title":"J Biol Chem"},{"key":"BF6363803_CR6","first-page":"549","volume":"10","author":"DS Huen","year":"1995","unstructured":"Huen DS, Henderson SA, Croom CD, Rowe M The Epstein\u2013Barr virus latent membrane protein-1 (LMP1) mediates activation of NF-kappa B and cell surface phenotype via two effector regions in its carboxy-terminal cytoplasmic domain Oncogene 1995 10 549\u2013560","journal-title":"Oncogene"},{"key":"BF6363803_CR7","doi-asserted-by":"publisher","first-page":"6478","DOI":"10.1093\/emboj\/16.21.6478","volume":"16","author":"A Kieser","year":"1997","unstructured":"Kieser A, Kilger E, Gires O, Ueffing M, Kolch W, Hammerschmidt W Epstein\u2013Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade EMBO J 1997 16 6478\u20136485","journal-title":"EMBO J"},{"key":"BF6363803_CR8","doi-asserted-by":"publisher","first-page":"3064","DOI":"10.1093\/emboj\/18.11.3064","volume":"18","author":"O Gires","year":"1999","unstructured":"Gires O, Kohlhuber F, Kilger E et al Latent membrane protein 1 of Epstein\u2013Barr virus interacts with JAK3 and activates STAT proteins EMBO J 1999 18 3064\u20133073","journal-title":"EMBO J"},{"key":"BF6363803_CR9","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1006\/viro.2000.0768","volume":"280","author":"M Vockerodt","year":"2001","unstructured":"Vockerodt M, Haier B, Buttgereit P, Tesch H, Kube D The Epstein\u2013Barr virus latent membrane protein 1 (LMP1) induces Interleukin-10 in Burkitt\u2019s lymphoma cells but not in Hodgkin\u2019s cells involving the p38\/SAPK2 pathway Virology 2001 280 183\u2013198","journal-title":"Virology"},{"key":"BF6363803_CR10","doi-asserted-by":"crossref","first-page":"2968","DOI":"10.1128\/jvi.69.5.2968-2976.1995","volume":"69","author":"T Mitchell","year":"1995","unstructured":"Mitchell T, Sudgen B Stimulation of NF-\u03baB-mediated transcription by mutant derivatives of the latent membrane protein of EBV J Virol 1995 69 2968\u20132972","journal-title":"J Virol"},{"key":"BF6363803_CR11","doi-asserted-by":"publisher","first-page":"1851","DOI":"10.1038\/sj.onc.1201359","volume":"15","author":"JE Floettmann","year":"1997","unstructured":"Floettmann JE, Rowe M Epstein\u2013Barr virus latent membrane protein-1 (LMP1) C-terminus activation region 2 (CTAR2) maps to the far C-terminus and requires oligomerisation for NF-kappaB activation Oncogene 1997 15 1851\u20131858","journal-title":"Oncogene"},{"key":"BF6363803_CR12","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/0092-8674(95)90489-1","volume":"80","author":"G Mosialos","year":"1995","unstructured":"Mosialos G, Birkenbach M, Yalamanchili R, Van AT, Ware C, Kieff E The Epstein\u2013Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family Cell 1995 80 389\u2013399","journal-title":"Cell"},{"key":"BF6363803_CR13","doi-asserted-by":"publisher","first-page":"11085","DOI":"10.1073\/pnas.93.20.11085","volume":"93","author":"KM Kaye","year":"1996","unstructured":"Kaye KM, Devergne O, Harada JN et al Tumor necrosis factor receptor associated factor 2 is a mediator of NF-kappaB activation by latent infection membrane protein 1, the Epstein\u2013Barr virus transforming protein Proc Natl Acad Sci USA 1996 93 11085\u201311090","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF6363803_CR14","doi-asserted-by":"publisher","first-page":"1447","DOI":"10.1073\/pnas.94.4.1447","volume":"94","author":"KM Izumi","year":"1997","unstructured":"Izumi KM, Kaye KM, Kieff ED The Epstein\u2013Barr virus LMP1 amino acid sequence that engages tumor necrosis factor receptor associated factors is critical for primary B lymphocyte growth transformation Proc Natl Acad Sci USA 1997 94 1447\u20131452","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF6363803_CR15","doi-asserted-by":"publisher","first-page":"12592","DOI":"10.1073\/pnas.94.23.12592","volume":"94","author":"KM Izumi","year":"1997","unstructured":"Izumi KM, Kieff ED The Epstein\u2013Barr virus oncogene product latent membrane protein 1 engages the tumor necrosis factor receptor-associated death domain protein to mediate B lymphocyte growth transformation and activate NF-kappaB Proc Natl Acad Sci USA 1997 94 12592\u201312597","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF6363803_CR16","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.4049\/jimmunol.160.3.1116","volume":"160","author":"E Hatzivassiliou","year":"1998","unstructured":"Hatzivassiliou E, Miller WE, Raab TN, Kieff E, Mosialos G A fusion of the EBV latent membrane protein-1 (LMP1) transmembrane domains to the CD40 cytoplasmic domain is similar to LMP1 in constitutive activation of epidermal growth factor receptor expression, nuclear factor-kappaB, and stress-activated protein kinase J Immunol 1998 160 1116\u20131121","journal-title":"J Immunol"},{"key":"BF6363803_CR17","doi-asserted-by":"crossref","first-page":"7900","DOI":"10.1128\/JVI.72.10.7900-7908.1998","volume":"72","author":"O Devergne","year":"1998","unstructured":"Devergne O, McFarland EC, Mosialos G, Izumi KM, Ware CF, Kieff E Role of the TRAF binding site and NF-kappaB activation in Epstein\u2013Barr virus latent membrane protein 1-induced cell gene expression J Virol 1998 72 7900\u20137908","journal-title":"J Virol"},{"key":"BF6363803_CR18","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1002\/ijc.2910570218","volume":"57","author":"H Nakagomi","year":"1994","unstructured":"Nakagomi H, Dolcetti R, Bejarano MT, Pisa P, Kiessling R, Masucci MG The Epstein\u2013Barr virus latent membrane protein-1 (LMP1) induces interleukin-10 production in Burkitt lymphoma lines Int J Cancer 1994 57 240\u2013244","journal-title":"Int J Cancer"},{"key":"BF6363803_CR19","doi-asserted-by":"publisher","first-page":"2899","DOI":"10.1038\/sj.onc.1201258","volume":"14","author":"AG Eliopoulos","year":"1997","unstructured":"Eliopoulos AG, Stack M, Dawson CW et al Epstein\u2013Barr virus-encoded LMP1 and CD40 mediate IL-6 production in epithelial cells via an NF-kappaB pathway involving TNF receptor-associated factors Oncogene 1997 14 2899\u20132916","journal-title":"Oncogene"},{"key":"BF6363803_CR20","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1016\/0145-2126(96)00029-X","volume":"20","author":"SC Klein","year":"1996","unstructured":"Klein SC, Kube D, Abts H, Diehl V, Tesch H Promotion of IL8, IL10, TNFalpha and TNFbeta production by EBV infection Leuk Res 1996 20 633\u2013636","journal-title":"Leuk Res"},{"key":"BF6363803_CR21","doi-asserted-by":"crossref","first-page":"2918","DOI":"10.1182\/blood.V87.7.2918.bloodjournal8772918","volume":"87","author":"H Herbst","year":"1996","unstructured":"Herbst H, Foss HD, Samol J et al Frequent expression of interleukin-10 by Epstein\u2013Barr virus-harboring tumor cells of Hodgkin\u2019s disease Blood 1996 87 2918\u20132929","journal-title":"Blood"},{"key":"BF6363803_CR22","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1038\/sj.gene.6363641","volume":"1","author":"D Kube","year":"1999","unstructured":"Kube D, Laser H, von Knethen A, Tesch H The AT-rich region between \u221254 to \u221266 is important for the promoter activity of interleukin-10 in Epstein\u2013Barr virus positive Burkitt\u2019s lymphoma cells Genes Immun 1999 1 105\u2013114","journal-title":"Genes Immun"},{"key":"BF6363803_CR23","doi-asserted-by":"publisher","first-page":"6055","DOI":"10.1073\/pnas.100119497","volume":"97","author":"ED Cahir-McFarland","year":"2000","unstructured":"Cahir-McFarland ED, Davidson DM, Schauer SL, Duong J, Kieff E NF-kappa B inhibition causes spontaneous apoptosis in Epstein\u2013Barr virus-transformed lymphoblastoid cells Proc Natl Acad Sci USA 2000 97 6055\u20136060","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF6363803_CR24","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1074\/jbc.M003758200","volume":"276","author":"AM Mehl","year":"2001","unstructured":"Mehl AM, Floettmann JE, Jones M, Brennan P, Rowe M Characterization of intercellular adhesion molecule-1 regulation by Epstein\u2013Barr virus-encoded latent membrane protein-1 identifies pathways that cooperate with nuclear factor kappa B to activate transcription J Biol Chem 2001 276 984\u2013992","journal-title":"J Biol Chem"},{"key":"BF6363803_CR25","doi-asserted-by":"publisher","first-page":"4067","DOI":"10.1128\/MCB.12.9.4067","volume":"12","author":"TH Tan","year":"1992","unstructured":"Tan TH, Huang GP, Sica A et al Kappa B site-dependent activation of the interleukin-2 receptor alpha-chain gene promoter by human c-Rel Mol Cell Biol 1992 12 4067\u20134075","journal-title":"Mol Cell Biol"},{"key":"BF6363803_CR26","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1093\/intimm\/11.3.361","volume":"11","author":"HC Liou","year":"1999","unstructured":"Liou HC, Jin Z, Tumang J, Andjelic S, Smith KA, Liou ML c-Rel is crucial for lymphocyte proliferation but dispensable for T cell effector function Int Immunol 1999 11 361\u2013371","journal-title":"Int Immunol"},{"key":"BF6363803_CR27","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1016\/0145-2126(90)90107-K","volume":"14","author":"H Tesch","year":"1990","unstructured":"Tesch H, Hermann T, Abts H et al High affinity IL-2 receptor on a Hodgkin\u2019s derived cell line Leuk Res 1990 14 953\u2013960","journal-title":"Leuk Res"},{"key":"BF6363803_CR28","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1128\/JVI.73.2.1630-1636.1999","volume":"73","author":"D Kube","year":"1999","unstructured":"Kube D, Vockerodt M, Weber O et al Expression of Epstein\u2013Barr virus nuclear antigen I is associated with enhanced expression of CD25 in the Hodgkin cell line L428 J Virol 1999 73 1630\u20131636","journal-title":"J Virol"},{"key":"BF6363803_CR29","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1093\/annonc\/7.suppl_4.S5","volume":"7","author":"AF Jarrett","year":"1996","unstructured":"Jarrett AF, Armstrong AA, Alexander E Epidemiology of EBV and Hodgkin\u2019s lymphoma Ann Oncol 1996 7 5\u201310","journal-title":"Ann Oncol"},{"key":"BF6363803_CR30","doi-asserted-by":"publisher","first-page":"pp\u2009155","DOI":"10.1385\/1-59259-227-9:155","volume-title":"Epstein Barr Virus Protocols. Methods in Molecular Biology","author":"D Kube","year":"2001","unstructured":"Kube D, Vockerodt M Transient gene expression and MACS enrichment. In: Wilson JB (ed) Epstein Barr Virus Protocols. Methods in Molecular Biology Humana: Totowa 2001 pp\u2009155\u2013164"},{"key":"BF6363803_CR31","doi-asserted-by":"publisher","first-page":"2383","DOI":"10.1038\/sj.onc.1202144","volume":"17","author":"JE Floettmann","year":"1998","unstructured":"Floettmann JE, Eliopoulos AG, Jones M, Young LS, Rowe M Epstein\u2013Barr virus latent membrane protein-1 (LMP1) signalling is distinct from CD40 and involves physical cooperation of its two C-terminus functional regions Oncogene 1998 17 2383\u20132392","journal-title":"Oncogene"},{"key":"BF6363803_CR32","doi-asserted-by":"publisher","first-page":"2961","DOI":"10.1172\/JCI119849","volume":"100","author":"RC Bargou","year":"1997","unstructured":"Bargou RC, Emmerich F, Krappmann D et al Constitutive NF\u03baB-RelA activation is required for proliferation and survival of Hodgkin disease tumor cells J Clin Invest 1997 100 2961\u20132974","journal-title":"J Clin Invest"},{"key":"BF6363803_CR33","doi-asserted-by":"publisher","first-page":"2131","DOI":"10.1038\/sj.onc.1201735","volume":"16","author":"KM Wood","year":"1998","unstructured":"Wood KM, Roff M, Hay R Defective I\u03baB\u03b1 in Hodgkin cell lines with constitutively active NF- Oncogene 1998 16 2131\u20132139","journal-title":"Oncogene"},{"key":"BF6363803_CR34","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1182\/blood.V98.3.762","volume":"98","author":"D Kube","year":"2001","unstructured":"Kube D, Holtick U, Vockerodt M et al STAT3 is constitutively activated in Hodgkin cell lines Blood 2001 98 762\u2013770","journal-title":"Blood"},{"key":"BF6363803_CR35","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1093\/annonc\/2.suppl_2.43","volume":"2","author":"A Gause","year":"1991","unstructured":"Gause A, Roschansky V, Tscjiersch A et al Low serum IL-2 receptor levels correlate with a good prognosis in patients with Hodgkin\u2019s lymphoma Ann Oncol 1991 2 43\u201347","journal-title":"Ann Oncol"},{"key":"BF6363803_CR36","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1093\/oxfordjournals.annonc.a059044","volume":"6","author":"G Enblad","year":"1995","unstructured":"Enblad G, Sundstrom C, Gronowitz S, Glimelius B Serum levels of interleukin-2 receptor (CD 25) in patients with Hodgkin\u2019s disease, with special reference to age and prognosis Ann Oncol 1995 6 65\u201370","journal-title":"Ann Oncol"},{"key":"BF6363803_CR37","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1002\/hon.2900130302","volume":"13","author":"SC Klein","year":"1995","unstructured":"Klein SC, J\u00fccker M, Abts H, Tesch H IL6 and IL6 receptor expression in Burkitt\u2019s lymphoma and lymphoblastoid cell lines: promotion of IL6 receptor expression by EBV Hematol Oncol 1995 13 121\u2013130","journal-title":"Hematol Oncol"},{"key":"BF6363803_CR38","doi-asserted-by":"publisher","first-page":"1450","DOI":"10.1084\/jem.160.5.1450","volume":"160","author":"TA Waldmann","year":"1984","unstructured":"Waldmann TA, Goldman CK, Robb RJ et al Expression of interleukin 2 receptors on activated human B cells J Exp Med 1984 160 1450\u20131466","journal-title":"J Exp Med"},{"key":"BF6363803_CR39","first-page":"1425","volume":"9","author":"D de Totero","year":"1995","unstructured":"de Totero D, Francia di Celle P, Cignetti A, Foa R The IL-2 receptor complex: expression and function on normal and leukemic B cells Leukemia 1995 9 1425\u20131431","journal-title":"Leukemia"},{"key":"BF6363803_CR40","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1126\/science.3008337","volume":"232","author":"TA Waldmann","year":"1986","unstructured":"Waldmann TA The structure, function, and expression of interleukin-2 receptors on normal and malignant lymphocytes Science 1986 232 727\u2013732","journal-title":"Science"},{"key":"BF6363803_CR41","first-page":"867","volume":"8","author":"I Crenon","year":"1993","unstructured":"Crenon I, Beraud C, Simard P, Montagne J, Veschambre P, Jalinot P The transcriptionally active factors mediating the effect of the HTLV-I Tax transactivator on the IL-2R alpha kappa B enhancer include the product of the c-rel proto-oncogene Oncogene 1993 8 867\u2013875","journal-title":"Oncogene"},{"key":"BF6363803_CR42","first-page":"717","volume":"136","author":"BC Wolf","year":"1990","unstructured":"Wolf BC, Martin AW, Neiman RS et al The detection of Epstein\u2013Barr virus in hairy cell leukemia cells by in situ hybridization Am J Pathol 1990 136 717\u2013723","journal-title":"Am J Pathol"},{"key":"BF6363803_CR43","first-page":"1571","volume":"8","author":"V Tsilivakos","year":"1994","unstructured":"Tsilivakos V, Tsapis A, Kakolyris S, Iliakis P, Perraki M, Georgoulias V Characterization of interleukin 2 receptors on B-cell chronic lymphocytic leukemia cells Leukemia 1994 8 1571\u20131578","journal-title":"Leukemia"},{"key":"BF6363803_CR44","first-page":"1714","volume":"142","author":"H Tesch","year":"1993","unstructured":"Tesch H, G\u00fcnther A, Abts H et al Expression of interleukin-2R\u03b1 and interleukin-2\u03b2 in Hodgkin\u2019s disease Am J Pathol 1993 142 1714\u20131720","journal-title":"Am J Pathol"},{"key":"BF6363803_CR45","doi-asserted-by":"crossref","first-page":"24424","DOI":"10.1016\/S0021-9258(19)51101-2","volume":"269","author":"FX Pimentel-Muinos","year":"1994","unstructured":"Pimentel-Muinos FX, Mazana J, Fresno M Regulation of interleukin-2 receptor alpha chain expression and nuclear factor.kappa B activation by protein kinase C in T lymphocytes. Autocrine role of tumor necrosis factor alpha J Biol Chem 1994 269 24424\u201324429","journal-title":"J Biol Chem"},{"key":"BF6363803_CR46","doi-asserted-by":"publisher","first-page":"1786","DOI":"10.1128\/MCB.15.3.1786","volume":"15","author":"S John","year":"1995","unstructured":"John S, Reeves R, Liu J, Child R et al Regulation of cell-type specific IL-2R expression. Potential role of interactions between Elf-1, HMD-I(Y) and NF\u03baB Mol Cell Biol 1995 15 1786\u20131792","journal-title":"Mol Cell Biol"},{"key":"BF6363803_CR47","doi-asserted-by":"publisher","first-page":"1700","DOI":"10.1093\/emboj\/17.6.1700","volume":"17","author":"E Kilger","year":"1998","unstructured":"Kilger E, Kieser A, Baumann M, Hammerschmidt W Epstein\u2013Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor EMBO J 1998 17 1700\u20131709","journal-title":"EMBO J"},{"key":"BF6363803_CR48","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1002\/eji.1830260517","volume":"26","author":"EL Burlinson","year":"1996","unstructured":"Burlinson EL, Graber P, Bonnefoy JY, Ozanne BW, Cushley W Soluble CD40 ligand induces expression of CD25 and CD23 in resting human tonsillar B lymphocytes Eur J Immunol 1996 26 1069\u20131073","journal-title":"Eur J Immunol"},{"key":"BF6363803_CR49","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1182\/blood.V80.2.484.484","volume":"80","author":"H Herbst","year":"1992","unstructured":"Herbst H, Steinbrecher E, Niedobitek G et al Distribution and phenotype of Epstein\u2013Barr virus-harboring cells in Hodgkin\u2019s disease Blood 1992 80 484\u2013491","journal-title":"Blood"},{"key":"BF6363803_CR50","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1093\/oxfordjournals.annonc.a059218","volume":"6","author":"M Gorschluter","year":"1995","unstructured":"Gorschluter M, Bohlen H, Hasenclever D, Diehl V, Tesch H Serum cytokine levels correlate with clinical parameters in Hodgkin\u2019s disease Ann Oncol 1995 6 477\u2013482","journal-title":"Ann Oncol"},{"key":"BF6363803_CR51","first-page":"92","volume":"8","author":"J Burton","year":"1994","unstructured":"Burton J, Kay NE Does IL-2 receptor expression and secretion in chronic B-cell leukemia have a role in down-regulation of the immune system? Leukemia 1994 8 92\u201396","journal-title":"Leukemia"},{"key":"BF6363803_CR52","doi-asserted-by":"crossref","first-page":"5430","DOI":"10.4049\/jimmunol.161.10.5430","volume":"161","author":"DM Eicher","year":"1998","unstructured":"Eicher DM, Waldmann TA IL-2R alpha on one cell can present IL-2 to IL-2R beta\/gmma(c) on another cell to augment IL-2 signaling J Immunol 1998 161 5430\u20135437","journal-title":"J Immunol"},{"key":"BF6363803_CR53","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1146\/annurev.immunol.15.1.405","volume":"15","author":"AB Rickinson","year":"1997","unstructured":"Rickinson AB, Moss DJ Human cytotoxic T lymphocyte responses to Epstein\u2013Barr virus infection Annu Rev Immunol 1997 15 405\u2013431","journal-title":"Annu Rev Immunol"}],"container-title":["Genes & Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/6363803.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/6363803","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/6363803.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T17:09:16Z","timestamp":1682356156000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/6363803"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,12,1]]},"references-count":53,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2001,12,1]]}},"alternative-id":["BF6363803"],"URL":"https:\/\/doi.org\/10.1038\/sj.gene.6363803","relation":{},"ISSN":["1466-4879","1476-5470"],"issn-type":[{"value":"1466-4879","type":"print"},{"value":"1476-5470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,12,1]]},"assertion":[{"value":"4 December 2001","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}