{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T16:08:01Z","timestamp":1761235681194},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2002,5,1]],"date-time":"2002-05-01T00:00:00Z","timestamp":1020211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2002,5,1]],"date-time":"2002-05-01T00:00:00Z","timestamp":1020211200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Genes Immun"],"published-print":{"date-parts":[[2002,5,1]]},"DOI":"10.1038\/sj.gene.6363825","type":"journal-article","created":{"date-parts":[[2002,9,5]],"date-time":"2002-09-05T18:28:38Z","timestamp":1031250518000},"page":"136-143","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Tyrosine 759 of the cytokine receptor gp130 is involved in Listeria monocytogenes susceptibility"],"prefix":"10.1038","volume":"3","author":[{"given":"D","family":"Kamimura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y","family":"Matsuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Atsumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Ohtani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S J","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Ishihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Hirano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2002,5,21]]},"reference":[{"key":"BF6363825_CR1","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.4049\/jimmunol.128.4.1903","volume":"128","author":"T Teranishi","year":"1982","unstructured":"Teranishi T, Hirano T, Arima N, Onoue K . Human helper T cell factor(s) (ThF). II. Induction of IgG production in B lymphoblastoid cell lines and identification of T cell-replacing factor- (TRF) like factor(s) J Immunol 1982 128: 1903\u20131908","journal-title":"J Immunol"},{"key":"BF6363825_CR2","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1038\/324073a0","volume":"324","author":"T Hirano","year":"1986","unstructured":"Hirano T, Yasukawa K, Harada H et al. Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin Nature 1986 324: 73\u201376","journal-title":"Nature"},{"key":"BF6363825_CR3","doi-asserted-by":"publisher","first-page":"249","DOI":"10.3109\/08830189809042997","volume":"16","author":"T Hirano","year":"1998","unstructured":"Hirano T . Interleukin 6 and its receptor: ten years later Int Rev Immunol 1998 16: 249\u2013284","journal-title":"Int Rev Immunol"},{"key":"BF6363825_CR4","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/S1359-6101(98)80005-1","volume":"8","author":"T Hirano","year":"1997","unstructured":"Hirano T, Nakajima K, Hibi M . Signaling mechanisms through gp130: a model of the cytokine system Cytokine Growth Factor Rev 1997 8: 241\u2013252","journal-title":"Cytokine Growth Factor Rev"},{"key":"BF6363825_CR5","doi-asserted-by":"publisher","first-page":"6523","DOI":"10.1074\/jbc.270.12.6523","volume":"270","author":"JW Tanner","year":"1995","unstructured":"Tanner JW, Chen W, Young RL, Longmore GD, Shaw AS . The conserved box 1 motif of cytokine receptors is required for association with JAK kinases J Biol Chem 1995 270: 6523\u20136530","journal-title":"J Biol Chem"},{"key":"BF6363825_CR6","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1016\/0092-8674(90)90411-7","volume":"63","author":"M Hibi","year":"1990","unstructured":"Hibi M, Murakami M, Saito M et al. Molecular cloning and expression of an IL-6 signal transducer, gp130 Cell 1990 63: 1149\u20131157","journal-title":"Cell"},{"key":"BF6363825_CR7","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1016\/S1074-7613(00)80501-4","volume":"5","author":"T Fukada","year":"1996","unstructured":"Fukada T, Hibi M, Yamanaka Y et al. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis Immunity 1996 5: 449\u2013460","journal-title":"Immunity"},{"key":"BF6363825_CR8","doi-asserted-by":"publisher","first-page":"4109","DOI":"10.1128\/MCB.18.7.4109","volume":"18","author":"M Takahashi-Tezuka","year":"1998","unstructured":"Takahashi-Tezuka M, Yoshida Y, Fukada T et al. Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase Mol Cell Biol 1998 18: 4109\u20134117","journal-title":"Mol Cell Biol"},{"key":"BF6363825_CR9","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1182\/blood.V93.6.1809.406k35_1809_1816","volume":"93","author":"K Nishida","year":"1999","unstructured":"Nishida K, Yoshida Y, Itoh M et al. Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors Blood 1999 93: 1809\u20131816","journal-title":"Blood"},{"key":"BF6363825_CR10","doi-asserted-by":"publisher","first-page":"3695","DOI":"10.1128\/MCB.20.10.3695-3704.2000","volume":"20","author":"M Itoh","year":"2000","unstructured":"Itoh M, Yoshida Y, Nishida K et al. Role of Gab1 in heart, placenta, and skin development and growth factor- and cytokine-induced extracellular signal-regulated kinase mitogen- activated protein kinase activation Mol Cell Biol 2000 20: 3695\u20133704","journal-title":"Mol Cell Biol"},{"key":"BF6363825_CR11","doi-asserted-by":"publisher","first-page":"6493","DOI":"10.1073\/pnas.100135197","volume":"97","author":"SE Nicholson","year":"2000","unstructured":"Nicholson SE, De Souza D, Fabri LJ et al. Suppressor of cytokine signaling-3 preferentially binds to the SHP-2- binding site on the shared cytokine receptor subunit gp130 Proc Natl Acad Sci USA 2000 97: 6493\u20136498","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF6363825_CR12","doi-asserted-by":"publisher","first-page":"12848","DOI":"10.1074\/jbc.275.17.12848","volume":"275","author":"J Schmitz","year":"2000","unstructured":"Schmitz J, Weissenbach M, Haan S, Heinrich PC, Schaper F . SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130 J Biol Chem 2000 275: 12848\u201312856","journal-title":"J Biol Chem"},{"key":"BF6363825_CR13","doi-asserted-by":"publisher","first-page":"1557","DOI":"10.1002\/j.1460-2075.1996.tb00500.x","volume":"15","author":"Y Yamanaka","year":"1996","unstructured":"Yamanaka Y, Nakajima K, Fukada T, Hibi M, Hirano T . Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation EMBO J 1996 15: 1557\u20131565","journal-title":"EMBO J"},{"key":"BF6363825_CR14","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/S1074-7613(00)80162-4","volume":"12","author":"T Ohtani","year":"2000","unstructured":"Ohtani T, Ishihara K, Atsumi T et al. Dissection of signaling cascades through gp130 in vivo: reciprocal roles for STAT3- and SHP2-mediated signals in immune responses Immunity 2000 12: 95\u2013105","journal-title":"Immunity"},{"key":"BF6363825_CR15","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/S0952-7915(97)80156-2","volume":"9","author":"ER Unanue","year":"1997","unstructured":"Unanue ER . Inter-relationship among macrophages, natural killer cells and neutrophils in early stages of Listeria resistance Curr Opin Immunol 1997 9: 35\u201343","journal-title":"Curr Opin Immunol"},{"key":"BF6363825_CR16","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1038\/368339a0","volume":"368","author":"M Kopf","year":"1994","unstructured":"Kopf M, Baumann H, Freer G et al. Impaired immune and acute-phase responses in interleukin-6-deficient mice Nature 1994 368: 339\u2013342","journal-title":"Nature"},{"key":"BF6363825_CR17","doi-asserted-by":"crossref","first-page":"2262","DOI":"10.1128\/iai.63.6.2262-2268.1995","volume":"63","author":"SA Dalrymple","year":"1995","unstructured":"Dalrymple SA, Lucian LA, Slattery R et al. Interleukin-6-deficient mice are highly susceptible to Listeria monocytogenes infection: correlation with inefficient neutrophilia Infect Immun 1995 63: 2262\u20132268","journal-title":"Infect Immun"},{"key":"BF6363825_CR18","doi-asserted-by":"crossref","first-page":"3231","DOI":"10.1128\/iai.64.8.3231-3235.1996","volume":"64","author":"SA Dalrymple","year":"1996","unstructured":"Dalrymple SA, Slattery R, Aud DM et al. Interleukin-6 is required for a protective immune response to systemic Escherichia coli infection Infect Immun 1996 64: 3231\u20133235","journal-title":"Infect Immun"},{"key":"BF6363825_CR19","doi-asserted-by":"crossref","first-page":"2790","DOI":"10.1128\/iai.63.7.2790-2792.1995","volume":"63","author":"Z Liu","year":"1995","unstructured":"Liu Z, Simpson RJ, Cheers C . Role of interleukin-6 in T-cell activation during primary and secondary infection with Listeria monocytogenes Infect Immun 1995 63: 2790\u20132792","journal-title":"Infect Immun"},{"key":"BF6363825_CR20","doi-asserted-by":"publisher","first-page":"1955","DOI":"10.1084\/jem.188.10.1955","volume":"188","author":"UAK Betz","year":"1998","unstructured":"Betz UAK, Bloch W, van den Broek M et al. Postnatally induced inactivation of gp130 in mice results in neurological, cardiac, hematopoietic, immunological, hepatic, and pulmonary defects J Exp Med 1998 188: 1955\u20131965","journal-title":"J Exp Med"},{"key":"BF6363825_CR21","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1038\/85812","volume":"27","author":"VL Boyartchuk","year":"2001","unstructured":"Boyartchuk VL, Broman KW, Mosher RE et al. Multigenic control of Listeria monocytogenes susceptibility in mice Nat Genet 2001 27: 259\u2013260","journal-title":"Nat Genet"},{"key":"BF6363825_CR22","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1159\/000133993","volume":"70","author":"C Rodriguez","year":"1995","unstructured":"Rodriguez C, Grosgeorge J, Nguyen VC, Gaudray P, Theillet C . Human gp130 transducer chain gene (IL6ST) is localized to chromosome band 5q11 and possesses a pseudogene on chromosome band 17p11 Cytogenet Cell Genet 1995 70: 64\u201367","journal-title":"Cytogenet Cell Genet"},{"key":"BF6363825_CR23","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1128\/iai.19.3.755-762.1978","volume":"19","author":"C Cheers","year":"1978","unstructured":"Cheers C, McKenzie IF . Resistance and susceptibility of mice to bacterial infection: genetics of listeriosis Infect Immun 1978 19: 755\u2013762","journal-title":"Infect Immun"},{"key":"BF6363825_CR24","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/1074-7613(95)90163-9","volume":"3","author":"JT Harty","year":"1995","unstructured":"Harty JT, Bevan MJ . Specific immunity to Listeria monocytogenes in the absence of IFN gamma Immunity 1995 3: 109\u2013117","journal-title":"Immunity"},{"key":"BF6363825_CR25","doi-asserted-by":"crossref","first-page":"5297","DOI":"10.4049\/jimmunol.158.11.5297","volume":"158","author":"WJ Dai","year":"1997","unstructured":"Dai WJ, Bartens W, Kohler G et al. Impaired macrophage listericidal and cytokine activities are responsible for the rapid death of Listeria monocytogenes-infected IFN- gamma receptor-deficient mice J Immunol 1997 158: 5297\u20135304","journal-title":"J Immunol"},{"key":"BF6363825_CR26","doi-asserted-by":"publisher","first-page":"8233","DOI":"10.1073\/pnas.95.14.8233","volume":"95","author":"B Lu","year":"1998","unstructured":"Lu B, Ebensperger C, Dembic Z et al. Targeted disruption of the interferon-gamma receptor 2 gene results in severe immune defects in mice Proc Natl Acad Sci USA 1998 95: 8233\u20138238","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF6363825_CR27","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1016\/0092-8674(95)90418-2","volume":"80","author":"T Tanaka","year":"1995","unstructured":"Tanaka T, Akira S, Yoshida K et al. Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages Cell 1995 80: 353\u2013361","journal-title":"Cell"},{"key":"BF6363825_CR28","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/S0956-7135(99)00067-5","volume":"11","author":"PF Almeida","year":"2000","unstructured":"Almeida PF, Almeida RCC . A PCR protocol using inl gene as a target for specific detection of Listeria monocytogenes Food Control 2000 11: 97\u2013101","journal-title":"Food Control"},{"key":"BF6363825_CR29","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1111\/j.1348-0421.1995.tb02211.x","volume":"39","author":"T Nishibori","year":"1995","unstructured":"Nishibori T, Cooray K, Xiong H et al. Correlation between the presence of virulence-associated genes as determined by PCR and actual virulence to mice in various strains of Listeria spp Microbiol Immunol 1995 39: 343\u2013349","journal-title":"Microbiol Immunol"},{"key":"BF6363825_CR30","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1093\/oxfordjournals.jbchem.a122416","volume":"104","author":"N Tonouchi","year":"1988","unstructured":"Tonouchi N, Oouchi N, Kashima N et al. High-level expression of human BSF-2\/IL-6 cDNA in Escherichia coli using a new type of expression-preparation system J Biochem (Tokyo) 1988 104: 30\u201334","journal-title":"J Biochem (Tokyo)"},{"key":"BF6363825_CR31","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1159\/000133423","volume":"61","author":"Y Matsuda","year":"1992","unstructured":"Matsuda Y, Harada YN, Natsuume-Sakai S et al. Location of the mouse complement factor H gene (cfh) by FISH analysis and replication R-banding Cytogenet Cell Genet 1992 61: 282\u2013285","journal-title":"Cytogenet Cell Genet"},{"key":"BF6363825_CR32","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1002\/elps.1150160142","volume":"16","author":"Y Matsuda","year":"1995","unstructured":"Matsuda Y, Chapman VM . Application of fluorescence in situ hybridization in genome analysis of the mouse Electrophoresis 1995 16: 261\u2013272","journal-title":"Electrophoresis"}],"container-title":["Genes &amp; Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/6363825.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/6363825","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/6363825.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T01:46:56Z","timestamp":1682041616000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/6363825"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,5,1]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2002,5,1]]}},"alternative-id":["BF6363825"],"URL":"https:\/\/doi.org\/10.1038\/sj.gene.6363825","relation":{},"ISSN":["1466-4879","1476-5470"],"issn-type":[{"value":"1466-4879","type":"print"},{"value":"1476-5470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,5,1]]},"assertion":[{"value":"23 August 2001","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 October 2001","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 October 2001","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 May 2002","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}