{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T09:43:14Z","timestamp":1790847794624,"version":"4.1.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2005,6,3]],"date-time":"2005-06-03T00:00:00Z","timestamp":1117756800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2005,6,3]],"date-time":"2005-06-03T00:00:00Z","timestamp":1117756800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Genes Immun"],"published-print":{"date-parts":[[2005,8,1]]},"DOI":"10.1038\/sj.gene.6364229","type":"journal-article","created":{"date-parts":[[2005,6,3]],"date-time":"2005-06-03T09:28:30Z","timestamp":1117790910000},"page":"457-458","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["No evidence for association between 1858 C\/T single-nucleotide polymorphism of PTPN22 gene and primary Sj\u00f6gren's syndrome"],"prefix":"10.1038","volume":"6","author":[{"given":"M","family":"Ittah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J-E","family":"Gottenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Proust","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Hachulla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X","family":"Puechal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Loiseau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X","family":"Mariette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Miceli-Richard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2005,6,3]]},"reference":[{"key":"BF6364229_CR1","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1038\/ng1323","volume":"36","author":"N Bottini","year":"2004","unstructured":"Bottini N, Musumeci L, Alonso A et al. A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet 2004; 36: 337\u2013338.","journal-title":"Nat Genet"},{"key":"BF6364229_CR2","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1086\/423790","volume":"75","author":"C Kyogoku","year":"2004","unstructured":"Kyogoku C, Langefeld CD, Ortmann WA et al. Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. Am J Hum Genet 2004; 75: 504\u2013507.","journal-title":"Am J Hum Genet"},{"key":"BF6364229_CR3","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1086\/422827","volume":"75","author":"AB Begovich","year":"2004","unstructured":"Begovich AB, Carlton VE, Honigberg LA et al. A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet 2004; 75: 330\u2013337.","journal-title":"Am J Hum Genet"},{"key":"BF6364229_CR4","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1002\/art.20771","volume":"52","author":"G Orozco","year":"2005","unstructured":"Orozco G, Sanchez E, Gonzalez-GAy MA et al. Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus eryhtematosus. Arthritis Rheum 2005; 52: 219\u2013224.","journal-title":"Arthritis Rheum"},{"key":"BF6364229_CR5","doi-asserted-by":"publisher","first-page":"5862","DOI":"10.1210\/jc.2004-1108","volume":"89","author":"MR Velaga","year":"2004","unstructured":"Velaga MR, Wilson V, Jennings CE et al. The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease. J Clin Endocrinol Metab 2004; 89: 5862\u20135866.","journal-title":"J Clin Endocrinol Metab"},{"key":"BF6364229_CR6","doi-asserted-by":"publisher","first-page":"d918","DOI":"10.2741\/A821","volume":"7","author":"T Mustelin","year":"2002","unstructured":"Mustelin T, Abraham RT, Rudd CE, Alonso A, Merlo JJ . Protein tyrosine phosphorylation in T cell signaling. Front Biosci 2002; 7: d918\u2013d969.","journal-title":"Front Biosci"},{"key":"BF6364229_CR7","doi-asserted-by":"publisher","first-page":"748","DOI":"10.7326\/0003-4819-101-6-748","volume":"101","author":"JD Reveille","year":"1984","unstructured":"Reveille JD, Wilson RW, Provost TT, Bias WB, Arnett FC . Primary Sj\u00f6gren's syndrome and other autoimmune diseases in families. Prevalence and immunogenetic studies in six kindreds. Ann Intern Med 1984; 101: 748\u2013756.","journal-title":"Ann Intern Med"},{"key":"BF6364229_CR8","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1086\/427244","volume":"76","author":"AB Begovich","year":"2005","unstructured":"Begovich AB, Caillier SJ, Alexander HC et al. The R620W polymorphism of the protein tyrosine phosphatase PTPN22 is not associated with multiple sclerosis. Am J Hum Genet. 2005; 76: 184\u2013187.","journal-title":"Am J Hum Genet."},{"key":"BF6364229_CR9","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1002\/art.20060","volume":"50","author":"JE Gottenberg","year":"2004","unstructured":"Gottenberg JE, Busson M, Loiseau P et al. Association of transforming growth factor beta1 and tumor necrosis factor alpha polymorphisms with anti-SSB\/La antibody secretion in patients with primary Sjogren's syndrome. Arthritis Rheum 2004; 50: 570\u2013580.","journal-title":"Arthritis Rheum"},{"key":"BF6364229_CR10","doi-asserted-by":"publisher","first-page":"2240","DOI":"10.1002\/art.11103","volume":"48","author":"JE Gottenberg","year":"2003","unstructured":"Gottenberg JE, Busson M, Loiseau P et al. In primary Sj\u00f6gren's syndrome, HLA class II is exclusively associated with autoantibody production and spreading of the autoimmune response. Arthritis Rheum 2003; 48: 2240\u20132245.","journal-title":"Arthritis Rheum"},{"key":"BF6364229_CR11","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1086\/429096","volume":"76","author":"LA Criswell","year":"2005","unstructured":"Criswell LA, Pfeiffer KA, Lum RF et al. Analysis of Families in the Multiple Autoimmune Disease Genetics Consortium (MADGC) Collection: the PTPN22 620W Allele Associates with Multiple Autoimmune Phenotypes. Am J Hum Genet 2005; 76: 561\u2013571.","journal-title":"Am J Hum Genet"}],"container-title":["Genes &amp; Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/6364229.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/6364229","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/6364229.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T20:20:08Z","timestamp":1647980408000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/6364229"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,6,3]]},"references-count":11,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,8,1]]}},"alternative-id":["BF6364229"],"URL":"https:\/\/doi.org\/10.1038\/sj.gene.6364229","relation":{},"ISSN":["1466-4879","1476-5470"],"issn-type":[{"value":"1466-4879","type":"print"},{"value":"1476-5470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,6,3]]},"assertion":[{"value":"10 February 2005","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 April 2005","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 April 2005","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 June 2005","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}