{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T19:02:14Z","timestamp":1791054134351,"version":"4.1.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2001,7,1]],"date-time":"2001-07-01T00:00:00Z","timestamp":993945600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Obes"],"published-print":{"date-parts":[[2001,7]]},"DOI":"10.1038\/sj.ijo.0801664","type":"journal-article","created":{"date-parts":[[2002,9,19]],"date-time":"2002-09-19T16:42:10Z","timestamp":1032453730000},"page":"1005-1011","source":"Crossref","is-referenced-by-count":202,"title":["The anorectic effect of a chronic peripheral infusion of amylin is abolished in area postrema\/nucleus of the solitary tract (AP\/NTS) lesioned rats"],"prefix":"10.1038","volume":"25","author":[{"given":"TA","family":"Lutz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Mollet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PA","family":"Rushing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Riediger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Scharrer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2001,7,6]]},"reference":[{"key":"BF0801664_CR1","doi-asserted-by":"publisher","first-page":"1197","DOI":"10.1016\/0031-9384(95)02067-5","volume":"58","author":"TA Lutz","year":"1995","unstructured":"Lutz TA, Geary N, Szabady MM, Del Prete E, Scharrer E . Amylin decreases meal size in rats Physiol Behav 1995 58: 1197\u20131202.","journal-title":"Physiol Behav"},{"key":"BF0801664_CR2","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/0006-8993(91)91644-G","volume":"539","author":"WT Chance","year":"1991","unstructured":"Chance WT, Balasubramaniam A, Zhang FS, Wimalawansa SJ, Fischer JE . Anorexia following the intrahypothalamic administration of amylin Brain Res 1991 539: 352\u2013354.","journal-title":"Brain Res"},{"key":"BF0801664_CR3","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/S0196-9781(97)00292-1","volume":"19","author":"TA Lutz","year":"1998","unstructured":"Lutz TA, Senn M, Althaus J, Del Prete E, Ehrensperger F, Scharrer E . Lesion of the area postrema\/nucleus of the solitary tract (AP\/NTS) attenuates the anorectic effects of amylin and calcitonin gene-related peptide (CGRP) in rats Peptides 1998 19: 309\u2013317.","journal-title":"Peptides"},{"key":"BF0801664_CR4","first-page":"R1777","volume":"274","author":"TA Lutz","year":"1998","unstructured":"Lutz TA, Althaus J, Rossi R, Scharrer E . Anorectic effect of amylin is not transmitted by capsaicin-sensitive nerve fibres Am J Physiol 1998 274: R1777\u2013R1782.","journal-title":"Am J Physiol"},{"key":"BF0801664_CR5","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1210\/endo.141.2.7378","volume":"141","author":"PA Rushing","year":"2000","unstructured":"Rushing PA, Hagan MM, Seeley RJ, Lutz TA, Woods SC . Amylin: a novel action in the brain to reduce body weight Endocrinology 2000 141: 850\u2013853.","journal-title":"Endocrinology"},{"key":"BF0801664_CR6","first-page":"R1654","volume":"271","author":"U Arnelo","year":"1996","unstructured":"Arnelo U, Permert J, Adrian TE, Larsson J, Westermark P, Reidelberger RD . Chronic infusion of islet amyloid polypeptide causes anorexia in rats Am J Physiol 1996 271: R1654\u2013R1659.","journal-title":"Am J Physiol"},{"key":"BF0801664_CR7","first-page":"R1537","volume":"275","author":"U Arnelo","year":"1998","unstructured":"Arnelo U, Reidelberger R, Adrian TE, Larsson J, Permert J . Sufficiency of postprandial plasma levels of islet amyloid polypeptide for suppression of feeding in rats Am J Physiol 1998 275: R1537\u2013R1542.","journal-title":"Am J Physiol"},{"key":"BF0801664_CR8","doi-asserted-by":"publisher","first-page":"1378","DOI":"10.1126\/science.280.5368.1378","volume":"280","author":"SC Woods","year":"1998","unstructured":"Woods SC, Seeley RJ, Porte D Jr, Schwartz MW . Signals that regulate food intake and energy homeostasis Science 1998 280: 1378\u20131383.","journal-title":"Science"},{"key":"BF0801664_CR9","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1055\/s-2007-978590","volume":"32","author":"PA Rushing","year":"2000","unstructured":"Rushing PA, Lutz TA, Seeley RJ, Woods SC . Amylin and insulin interact to reduce food intake in rats Horm Metab Res 2000 32: 62\u201365.","journal-title":"Horm Metab Res"},{"key":"BF0801664_CR10","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1006\/bbrc.1998.9308","volume":"250","author":"S Gebre-Medhin","year":"1998","unstructured":"Gebre-Medhin S, Mulder H, Pekny M, Westermark G, T\u00f6rnell J, Westermark P, Sundler F, Ahren B, Betsholtz C . Increased insulin secretion and glucose tolerance in mice lacking islet amyloid polypeptide (amylin) Biochem Biophys Res Commun 1998 250: 271\u2013277.","journal-title":"Biochem Biophys Res Commun"},{"key":"BF0801664_CR11","doi-asserted-by":"publisher","first-page":"1533","DOI":"10.1016\/S0196-9781(98)00114-4","volume":"19","author":"TA Lutz","year":"1998","unstructured":"Lutz TA, Rossi R, Althaus J, Del Prete E, Scharrer E . Amylin reduces food intake more potently than calcitonin gene-related peptide (CGRP) when injected in to the lateral brain ventricle in rats Peptides 1998 19: 1533\u20131540.","journal-title":"Peptides"},{"key":"BF0801664_CR12","first-page":"406.3","volume":"24","author":"GL Edwards","year":"1998","unstructured":"Edwards GL, Power JD, Young AA . Attenuation of the satiogenic effects of amylin by lesions of the area postrema, but not by intraperitoneal capsaicin. (Abstract) Soc Neurosci Abstr 1998 24: 406.3.","journal-title":"Soc Neurosci Abstr"},{"key":"BF0801664_CR13","first-page":"493","volume":"44","author":"K Beaumont","year":"1993","unstructured":"Beaumont K, Kenney MA, Young AA, Rink TJ . High affinity amylin binding sites in rat brain Mol Pharmac 1993 44: 493\u2013497.","journal-title":"Mol Pharmac"},{"key":"BF0801664_CR14","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1002\/(SICI)1098-2299(199604)37:4<231::AID-DDR5>3.0.CO;2-M","volume":"37","author":"AA Young","year":"1996","unstructured":"Young AA, Vine W, Gedulin BR, Pittner R, Janes S, Gaeta LSL, Percy A, Moore CX, Koda JE, Rink TJ, Beaumont K . Preclinical pharmacology of pramlintide in the rat: comparisons with human and rat amylin Drug Dev Res 1996 37: 231\u2013248.","journal-title":"Drug Dev Res"},{"key":"BF0801664_CR15","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/S0196-9781(99)00208-9","volume":"21","author":"TA Lutz","year":"2000","unstructured":"Lutz TA, Tschudy S, Rushing PA, Scharrer E . Amylin receptors mediate the anorectic action of salmon calcitonin (sCT) Peptides 2000 21: 233\u2013238.","journal-title":"Peptides"},{"key":"BF0801664_CR16","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.1016\/0031-9384(80)90053-0","volume":"24","author":"JJ McGlone","year":"1980","unstructured":"McGlone JJ, Ritter S, Kelley KW . The antiaggressive effect of lithium is abolished by area postrema lesion Physiol Behav 1980 24: 1095\u20131100.","journal-title":"Physiol Behav"},{"key":"BF0801664_CR17","first-page":"856.2","volume":"25","author":"T Riediger","year":"1999","unstructured":"Riediger T, Rauch M, Jurat G, Schmid HA . Cellular mechanisms of amylin activating area postrema and subfornical organ neurons. (Abstract) Soc Neurosci Abstr 1999 25: 856.2.","journal-title":"Soc Neurosci Abstr"},{"key":"BF0801664_CR18","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/S0167-0115(97)01034-3","volume":"71","author":"NE Rowland","year":"1997","unstructured":"Rowland NE, Crews EC, Gentry RM . Comparison of Fos induced in rat brain by GLP-1 and amylin Regul Pept 1997 71: 171\u2013174.","journal-title":"Regul Pept"},{"key":"BF0801664_CR19","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/S0006-8993(98)01348-1","volume":"820","author":"NE Rowland","year":"1999","unstructured":"Rowland NE, Richmond RM . Area postrema and the anorectic actions of dexfenfluramine and amylin Brain Res 1999 820: 86\u201391.","journal-title":"Brain Res"},{"key":"BF0801664_CR20","first-page":"847.10","volume":"24","author":"CC Miller","year":"1998","unstructured":"Miller CC, Dilts RP, Young AA, Edwards GL . Lesion of the area postrema (AP) attenuates hindbrain cFos expression after amylin treatment. (Abstract) Soc Neurosci Abstr 1998 24: 847.10.","journal-title":"Soc Neurosci Abstr"},{"key":"BF0801664_CR21","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1097\/00006676-199707000-00009","volume":"15","author":"J Permert","year":"1997","unstructured":"Permert J, Larsson J, Fruin, AB, Tatemoto K, Herrington MK, von Schenck H, Adrian TE . Islet hormone secretion in pancreatic cancer patients with diabetes Pancreas 1997 15: 60\u201368.","journal-title":"Pancreas"},{"key":"BF0801664_CR22","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1016\/0006-291X(89)92529-1","volume":"160","author":"H Ohsawa","year":"1989","unstructured":"Ohsawa H, Kanatsuka A, Yamaguchi T, Makino H, Yoshida S . Islet amyloid polypeptide inhibits glucose-stimulated insulin secretion from isolated rat pancreatic islets Biochem Biophys Res Commun 1989 160: 961\u2013967.","journal-title":"Biochem Biophys Res Commun"},{"key":"BF0801664_CR23","doi-asserted-by":"publisher","first-page":"R1","DOI":"10.1016\/0303-7207(92)90084-J","volume":"84","author":"AA Young","year":"1992","unstructured":"Young AA, Carlo P, Rink TJ, Wang MW . 8-37hCGRP, an amylin receptor antagonist, enhances the insulin response and perturbs the glucose response to infused arginine in anesthetized rats Mol Cell Endocrinol 1992 84: R1\u2013R5.","journal-title":"Mol Cell Endocrinol"},{"key":"BF0801664_CR24","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/S0031-9384(96)00361-7","volume":"61","author":"N Geary","year":"1997","unstructured":"Geary N, Asarian L, Langhans W . The satiating potency of hepatic portal glucagon in rats is not affected by insulin or insulin antibodies Physiol Behav 1997 61: 199\u2013208.","journal-title":"Physiol Behav"}],"container-title":["International Journal of Obesity"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/0801664.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/0801664","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/0801664.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T07:18:31Z","timestamp":1684221511000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/0801664"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,7]]},"references-count":24,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2001,7]]}},"alternative-id":["BF0801664"],"URL":"https:\/\/doi.org\/10.1038\/sj.ijo.0801664","relation":{},"ISSN":["0307-0565","1476-5497"],"issn-type":[{"value":"0307-0565","type":"print"},{"value":"1476-5497","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,7]]}}}