{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:13:03Z","timestamp":1787242383874,"version":"build-2736575974"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T00:00:00Z","timestamp":1160006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T00:00:00Z","timestamp":1160006400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Perinatol"],"published-print":{"date-parts":[[2006,12,1]]},"DOI":"10.1038\/sj.jp.7211611","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T12:12:07Z","timestamp":1160050327000},"page":"749-754","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Safety and efficacy of early amino acids in preterm <28 weeks gestation: prospective observational comparison"],"prefix":"10.1038","volume":"26","author":[{"given":"K","family":"Kotsopoulos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Benadiba-Torch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Cuddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P S","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,10,5]]},"reference":[{"key":"BF7211611_CR1","first-page":"252","volume":"18","author":"SJ Carlson","year":"1998","unstructured":"Carlson SJ, Ziegler EE . Nutrient intakes and growth of very low birth weight infants. J Perinatol 1998; 18: 252\u2013258.","journal-title":"J Perinatol"},{"key":"BF7211611_CR2","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1542\/peds.111.5.986","volume":"111","author":"RH Clark","year":"2003","unstructured":"Clark RH, Thomas P, Peabody J . Extrauterine growth restriction remains a serious problem in prematurely born neonates. Pediatrics 2003; 111: 986\u2013990.","journal-title":"Pediatrics"},{"key":"BF7211611_CR3","doi-asserted-by":"publisher","first-page":"F428","DOI":"10.1136\/adc.2001.004044","volume":"89","author":"RJ Cooke","year":"2004","unstructured":"Cooke RJ, Ainsworth SB, Fenton AC . Postnatal growth retardation: a universal problem in preterm infants. Arch Dis Child Fetal Neonatal Ed 2004; 89: F428\u2013F430.","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"BF7211611_CR4","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/S0095-5108(05)70024-5","volume":"27","author":"RA Ehrenkranz","year":"2000","unstructured":"Ehrenkranz RA . Growth outcomes of very low-birth weight infants in the newborn intensive care unit. Clin Perinatol 2000; 27: 325\u2013345.","journal-title":"Clin Perinatol"},{"key":"BF7211611_CR5","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1542\/peds.107.2.270","volume":"107","author":"NE Embleton","year":"2001","unstructured":"Embleton NE, Pang N, Cooke RJ . Postnatal malnutrition and growth retardation: an inevitable consequence of current recommendations in preterm infants? Pediatrics 2001; 107: 270\u2013273.","journal-title":"Pediatrics"},{"key":"BF7211611_CR6","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1542\/peds.100.4.647","volume":"100","author":"MA Berry","year":"1997","unstructured":"Berry MA, Abrahamowicz M, Usher RH . Factors associated with growth of extremely premature infants during initial hospitalization. Pediatrics 1997; 100: 640\u2013646.","journal-title":"Pediatrics"},{"key":"BF7211611_CR7","doi-asserted-by":"publisher","first-page":"1360","DOI":"10.1542\/peds.104.6.1360","volume":"104","author":"WW Hay Jr","year":"1999","unstructured":"Hay Jr WW, Lucas A, Heird WC, Ziegler E, Levin E, Grave GD et al. Workshop summary: nutrition of the extremely low birth weight infant. Pediatrics 1999; 104: 1360\u20131368.","journal-title":"Pediatrics"},{"key":"BF7211611_CR8","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1097\/00005176-199302000-00006","volume":"16","author":"RJ Cooke","year":"1993","unstructured":"Cooke RJ, Ford A, Werkman S, Conner C, Watson D . Postnatal growth in infants born between 700 And 1500 G. J Pediatr Gastroenterol Nutr 1993; 16: 130\u2013135.","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"Suppl 2","key":"BF7211611_CR9","doi-asserted-by":"publisher","first-page":"S7","DOI":"10.1038\/sj.jp.7211309","volume":"25","author":"DH Adamkin","year":"2005","unstructured":"Adamkin DH . Pragmatic approach to in-hospital nutrition in high-risk neonates. J Perinatol 2005; 25 (Suppl 2): S7\u2013S11.","journal-title":"J Perinatol"},{"key":"BF7211611_CR10","doi-asserted-by":"publisher","first-page":"943","DOI":"10.1056\/NEJM197211092871901","volume":"287","author":"WC Heird","year":"1972","unstructured":"Heird WC, Dell RB, Driscoll Jr JM, Grebin B, Winters RW . Metabolic acidosis resulting from intravenous alimentation mixtures containing synthetic amino acids. N Engl J Med 1972; 287: 943\u2013948.","journal-title":"N Engl J Med"},{"key":"BF7211611_CR11","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/S0022-3476(72)80395-0","volume":"81","author":"JD Johnson","year":"1972","unstructured":"Johnson JD, Albritton WL, Sunshine P . Hyperammonemia accompanying parenteral nutrition in newborn infants. J Pediatr 1972; 81: 154\u2013161.","journal-title":"J Pediatr"},{"key":"BF7211611_CR12","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1038\/sj.jp.7211114","volume":"24","author":"HM Ibrahim","year":"2004","unstructured":"Ibrahim HM, Jeroudi MA, Baier RJ, Dhanireddy R, Krouskop RW . Aggressive early total parental nutrition in low-birth-weight infants. J Perinatol 2004; 24: 482\u2013486.","journal-title":"J Perinatol"},{"key":"BF7211611_CR13","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1016\/j.jpeds.2005.05.038","volume":"147","author":"FW Te Braake","year":"2005","unstructured":"Te Braake FW, Van Den Akker CH, Wattimena DJ, Huijmans JG, Van Goudoever JB . Amino acid administration to premature infants directly after birth. J Pediatr 2005; 147: 457\u2013461.","journal-title":"J Pediatr"},{"key":"BF7211611_CR14","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1542\/peds.82.4.527","volume":"82","author":"AT Shennan","year":"1988","unstructured":"Shennan AT, Dunn MS, Ohlsson A, Lennox K, Hoskins EM . Abnormal pulmonary outcomes in premature infants: prediction from oxygen requirement in the neonatal period. Pediatrics 1988; 82: 527\u2013532.","journal-title":"Pediatrics"},{"key":"BF7211611_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/00000658-197801000-00001","volume":"187","author":"MJ Bell","year":"1978","unstructured":"Bell MJ, Ternberg JL, Feigin RD, Keating JP, Marshall R, Barton L et al. Neonatal necrotizing enterocolitis. Therapeutic decisions based upon clinical staging. Ann Surg 1978; 187: 1\u20137.","journal-title":"Ann Surg"},{"key":"BF7211611_CR16","doi-asserted-by":"publisher","first-page":"E35","DOI":"10.1542\/peds.108.2.e35","volume":"108","author":"MS Kramer","year":"2001","unstructured":"Kramer MS, Platt RW, Wen SW, Joseph KS, Allen A, Abrahamowicz M et al. A new and improved population-based Canadian reference for birth weight for gestational age. Pediatrics 2001; 108: E35.","journal-title":"Pediatrics"},{"key":"BF7211611_CR17","doi-asserted-by":"publisher","first-page":"E45","DOI":"10.1542\/pir.20-9-e45","volume":"20","author":"PJ Thureen","year":"1999","unstructured":"Thureen PJ . Early aggressive nutrition in the neonate. Pediatr Rev 1999; 20: E45\u2013E55.","journal-title":"Pediatr Rev"},{"key":"BF7211611_CR18","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/S0095-5108(05)70014-2","volume":"27","author":"PJ Thureen","year":"2000","unstructured":"Thureen PJ, Hay Jr WW . Intravenous nutrition and postnatal growth of the micropremie. Clin Perinatol 2000; 27: 197\u2013219.","journal-title":"Clin Perinatol"},{"key":"BF7211611_CR19","doi-asserted-by":"crossref","unstructured":"American academy of pediatrics committee on nutrition: nutritional needs of low-birth-weight infants. Pediatrics 1985; 75: 976\u2013986.","DOI":"10.1542\/peds.75.5.976"},{"key":"BF7211611_CR20","unstructured":"Nutrient Needs And Feeding Of Premature Infants. Nutrition Committee, Canadian Paediatric Society. CMAJ 1995; 152: 1765\u20131785."},{"key":"BF7211611_CR21","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1203\/00006450-200301000-00008","volume":"53","author":"PJ Thureen","year":"2003","unstructured":"Thureen PJ, Melara D, Fennessey PV, Hay Jr WW . Effect of low versus high intravenous amino acid intake on very low birth weight infants in the early neonatal period. Pediatr Res 2003; 53: 24\u201332.","journal-title":"Pediatr Res"},{"key":"BF7211611_CR22","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1097\/00005176-200202000-00013","volume":"34","author":"PJ Porcelli Jr","year":"2002","unstructured":"Porcelli Jr PJ, Sisk PM . Increased parenteral amino acid administration to extremely low-birth-weight infants during early postnatal life. J Pediatr Gastroenterol Nutr 2002; 34: 174\u2013179.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"BF7211611_CR23","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1016\/S0022-3476(95)70083-8","volume":"127","author":"JB Van Goudoever","year":"1995","unstructured":"Van Goudoever JB, Colen T, Wattimena JL, Huijmans JG, Carnielli VP, Sauer PJ . Immediate commencement of amino acid supplementation in preterm infants: effect on serum amino acid concentrations and protein kinetics on the first day of life. J Pediatr 1995; 127: 458\u2013465.","journal-title":"J Pediatr"},{"key":"BF7211611_CR24","doi-asserted-by":"publisher","first-page":"F4","DOI":"10.1136\/fn.77.1.F4","volume":"77","author":"DC Wilson","year":"1997","unstructured":"Wilson DC, Cairns P, Halliday HL, Reid M, Mcclure G, Dodge JA . Randomised controlled trial of an aggressive nutritional regimen in sick very low birthweight infants. Arch Dis Child Fetal Neonatal Ed 1997; 77: F4\u2013F11.","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"BF7211611_CR25","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1016\/0002-9378(82)90117-X","volume":"143","author":"M Hack","year":"1982","unstructured":"Hack M, Merkatz IR, Gordon D, Jones PK, Fanaroff AA . The prognostic significance of postnatal growth in very low-birth weight infants. Am J Obstet Gynecol 1982; 143: 693\u2013699.","journal-title":"Am J Obstet Gynecol"},{"key":"BF7211611_CR26","doi-asserted-by":"publisher","first-page":"E43","DOI":"10.1542\/pir.20-9-e43","volume":"20","author":"WC Heird","year":"1999","unstructured":"Heird WC . The importance of early nutritional management of low-birth weight infants. Pediatr Rev 1999; 20: E43\u2013E44.","journal-title":"Pediatr Rev"},{"key":"BF7211611_CR27","doi-asserted-by":"publisher","first-page":"1477","DOI":"10.1016\/0140-6736(90)93026-L","volume":"335","author":"A Lucas","year":"1990","unstructured":"Lucas A, Morley R, Cole TJ, Gore SM, Lucas PJ, Crowle P et al. Early diet in preterm babies and developmental status at 18 months. Lancet 1990; 335: 1477\u20131481.","journal-title":"Lancet"},{"key":"BF7211611_CR28","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1136\/bmj.309.6950.304","volume":"309","author":"A Lucas","year":"1994","unstructured":"Lucas A, Morley R . Does early nutrition in infants born before term programme later blood pressure? BMJ 1994; 309: 304\u2013308.","journal-title":"BMJ"},{"issue":"Suppl 2","key":"BF7211611_CR29","doi-asserted-by":"publisher","first-page":"S2","DOI":"10.1038\/sj.jp.7211308","volume":"25","author":"A Lucas","year":"2005","unstructured":"Lucas A . Long-term programming effects of early nutrition \u2013 implications for the preterm infant. J Perinatol 2005; 25 (Suppl 2): S2\u2013S6.","journal-title":"J Perinatol"},{"key":"BF7211611_CR30","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1542\/peds.80.5.693","volume":"80","author":"S Andronikou","year":"1987","unstructured":"Andronikou S, Hanning I . Parenteral nutrition effect on serum insulin in the preterm infant. Pediatrics 1987; 80: 693\u2013697.","journal-title":"Pediatrics"}],"container-title":["Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/7211611.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/7211611","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/7211611.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T12:31:44Z","timestamp":1647606704000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/7211611"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,5]]},"references-count":30,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2006,12,1]]}},"alternative-id":["BF7211611"],"URL":"https:\/\/doi.org\/10.1038\/sj.jp.7211611","relation":{},"ISSN":["0743-8346","1476-5543"],"issn-type":[{"value":"0743-8346","type":"print"},{"value":"1476-5543","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,5]]},"assertion":[{"value":"31 May 2006","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 August 2006","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 September 2006","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 October 2006","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}