{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T04:16:16Z","timestamp":1791173776062,"version":"4.1.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":3507,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["kidney-international.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2006,5]]},"DOI":"10.1038\/sj.ki.5000285","type":"journal-article","created":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T05:43:14Z","timestamp":1141191794000},"page":"1518-1525","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":151,"title":["Aquaporin-1 plays an essential role in water permeability and ultrafiltration during peritoneal dialysis"],"prefix":"10.1016","volume":"69","author":[{"given":"J.","family":"Ni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.-M.","family":"Verbavatz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Rippe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Boisd\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Moulin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Rippe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.S.","family":"Verkman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Devuyst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/sj.ki.5000285_bb0010","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1681\/ASN.V971285","article-title":"Increased peritoneal membrane transport is associated with decreased patient and technique survival for continuous ambulatory peritoneal dialysis patients","volume":"9","author":"Churchill","year":"1998","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/sj.ki.5000285_bb0015","doi-asserted-by":"crossref","first-page":"2948","DOI":"10.1097\/01.ASN.0000092146.67909.E2","article-title":"Survival of functionally anuric patients on automated peritoneal dialysis: the European APD Outcome Study","volume":"14","author":"Brown","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/sj.ki.5000285_bb0020","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1046\/j.1523-1755.1998.00180.x","article-title":"What really happens to people on long-term peritoneal dialysis?","volume":"54","author":"Davies","year":"1998","journal-title":"Kidney Int"},{"key":"10.1038\/sj.ki.5000285_bb0025","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/ki.1990.227","article-title":"A phenomenological interpretation of the variation in dialysate volume with dwell time in CAPD","volume":"38","author":"Stelin","year":"1990","journal-title":"Kidney Int"},{"key":"10.1038\/sj.ki.5000285_bb0030","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/ki.1991.216","article-title":"Computer simulations of peritoneal fluid transport in CAPD","volume":"40","author":"Rippe","year":"1991","journal-title":"Kidney Int"},{"key":"10.1038\/sj.ki.5000285_bb0035","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1177\/089686080402400102","article-title":"Fluid and electrolyte transport across the peritoneal membrane during CAPD","volume":"24","author":"Rippe","year":"2004","journal-title":"Perit Dial Int"},{"key":"10.1038\/sj.ki.5000285_bb0040","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1177\/089686080102100222","article-title":"Monitoring of long-term peritoneal membrane function","volume":"21","author":"Davies","year":"2001","journal-title":"Perit Dial Int"},{"key":"10.1038\/sj.ki.5000285_bb0045","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1111\/j.1523-1755.2004.00815.x","article-title":"Quantification of free water transport in peritoneal dialysis","volume":"66","author":"Smit","year":"2004","journal-title":"Kidney Int"},{"key":"10.1038\/sj.ki.5000285_bb0050","doi-asserted-by":"crossref","first-page":"F433","DOI":"10.1152\/ajprenal.00313.2004","article-title":"The transport barrier in intraperitoneal therapy","volume":"288","author":"Flessner","year":"2005","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1038\/sj.ki.5000285_bb0055","doi-asserted-by":"crossref","first-page":"4278","DOI":"10.1002\/anie.200460804","article-title":"Aquaporin water channels (Nobel Lecture)","volume":"43","author":"Agre","year":"2004","journal-title":"Angew Chem Int Edn"},{"key":"10.1038\/sj.ki.5000285_bb0060","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1126\/science.256.5055.385","article-title":"Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein","volume":"256","author":"Preston","year":"1992","journal-title":"Science"},{"issue":"Suppl 1","key":"10.1038\/sj.ki.5000285_bb0065","doi-asserted-by":"crossref","first-page":"7275","DOI":"10.1073\/pnas.90.15.7275","article-title":"Distribution of the aquaporin CHIP in secretory and resorptive epithelia and capillary endothelia","volume":"90","author":"Nielsen","year":"1993","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/sj.ki.5000285_bb0070","doi-asserted-by":"crossref","first-page":"S54","DOI":"10.1177\/089686089601601S08","article-title":"Demonstration of aquaporin-CHIP in peritoneal tissue of uremic and CAPD patients","volume":"16","author":"Pannekeet","year":"1996","journal-title":"Perit Dial Int"},{"key":"10.1038\/sj.ki.5000285_bb0075","first-page":"H234","article-title":"Aquaporin-1 and endothelial nitric oxide synthase expression in capillary endothelia of human peritoneum","volume":"275","author":"Devuyst","year":"1998","journal-title":"Am J Physiol"},{"key":"10.1038\/sj.ki.5000285_bb0080","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/35036519","article-title":"Structural determinants of water permeation through aquaporin-1","volume":"407","author":"Murata","year":"2000","journal-title":"Nature"},{"key":"10.1038\/sj.ki.5000285_bb0085","first-page":"H2254","article-title":"In vivo inhibition of transcellular water channels (aquaporin-1) during acute peritoneal dialysis in rats","volume":"271","author":"Carlsson","year":"1996","journal-title":"Am J Physiol"},{"key":"10.1038\/sj.ki.5000285_bb0090","first-page":"60","article-title":"Amphotericin B, mercury chloride and peritoneal transport in rabbits","volume":"56","author":"Zweers","year":"2001","journal-title":"Clin Nephrol"},{"key":"10.1038\/sj.ki.5000285_bb0095","doi-asserted-by":"crossref","first-page":"C76","DOI":"10.1152\/ajpcell.1999.276.1.C76","article-title":"Reduced osmotic water permeability of the peritoneal barrier in aquaporin-1 knockout mice","volume":"276","author":"Yang","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1038\/sj.ki.5000285_bb0100","doi-asserted-by":"crossref","first-page":"3205","DOI":"10.1097\/01.ASN.0000099382.18284.57","article-title":"Mice that lack endothelial nitric oxide synthase are protected against functional and structural modifications induced by acute peritonitis","volume":"14","author":"Ni","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/sj.ki.5000285_bb0105","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1111\/j.1523-1755.2005.00304.x","article-title":"Functional and molecular characterization of a peritoneal dialysis model in the C57BL\/6J mouse","volume":"67","author":"Ni","year":"2005","journal-title":"Kidney Int"},{"key":"10.1038\/sj.ki.5000285_bb0110","doi-asserted-by":"crossref","first-page":"4296","DOI":"10.1074\/jbc.273.8.4296","article-title":"Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels","volume":"273","author":"Ma","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1038\/sj.ki.5000285_bb0115","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1159\/000170209","article-title":"Intraperitoneal fluid volume changes during peritoneal dialysis in the rat. Indicator dilution vs volumetric measurements","volume":"13","author":"Zakaria","year":"1995","journal-title":"Blood Purif"},{"key":"10.1038\/sj.ki.5000285_bb0120","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1172\/JCI4138","article-title":"Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice","volume":"103","author":"Bai","year":"1999","journal-title":"J Clin Invest"},{"key":"10.1038\/sj.ki.5000285_bb0125","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1172\/JCI8214","article-title":"Requirement of aquaporin-1 for NaCl-driven water transport across descending vasa recta","volume":"105","author":"Pallone","year":"2000","journal-title":"J Clin Invest"},{"key":"10.1038\/sj.ki.5000285_bb0130","doi-asserted-by":"crossref","first-page":"20071","DOI":"10.1074\/jbc.274.29.20071","article-title":"Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels","volume":"274","author":"Ma","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1038\/sj.ki.5000285_bb0135","series-title":"Textbook of Peritoneal Dialysis","first-page":"135","article-title":"The physiology of peritoneal solute transport and ultrafiltration","author":"Krediet","year":"2000"},{"key":"10.1038\/sj.ki.5000285_bb0140","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S0272-6386(99)70317-3","article-title":"Expression of aquaporin-1 in a long-term peritoneal dialysis patient with impaired transcellular water transport","volume":"33","author":"Goffin","year":"1999","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/sj.ki.5000285_bb0145","doi-asserted-by":"crossref","first-page":"S30","DOI":"10.1177\/089686080102103S05","article-title":"Aquaporins are unlikely to be affected in marked ultrafiltration failure: results from a computer simulation","volume":"21","author":"Rippe","year":"2001","journal-title":"Perit Dial Int"},{"key":"10.1038\/sj.ki.5000285_bb0150","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1097\/01.ASN.0000053420.37216.9E","article-title":"Corticosteroids induce expression of aquaporin-1 and increase transcellular water transport in rat peritoneum","volume":"14","author":"Stoenoiu","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/sj.ki.5000285_bb0155","doi-asserted-by":"crossref","first-page":"S95","DOI":"10.1177\/089686089901902S15","article-title":"Role of transcellular water channels in peritoneal dialysis","volume":"19","author":"Rippe","year":"1999","journal-title":"Perit Dial Int"},{"key":"10.1038\/sj.ki.5000285_bb0160","series-title":"The peritoneal microcirculation in peritoneal dialysis","first-page":"107","author":"White","year":"2000"},{"key":"10.1038\/sj.ki.5000285_bb0165","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1177\/089686089401400412","article-title":"Hormonal, blood pressure, and peritoneal transport response to short-term ACE inhibition","volume":"14","author":"Ripley","year":"1994","journal-title":"Perit Dial Int"},{"key":"10.1038\/sj.ki.5000285_bb0170","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1681\/ASN.V8121946","article-title":"Blood flow limitations of solute transport across the visceral peritoneum","volume":"8","author":"Kim","year":"1997","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/sj.ki.5000285_bb0175","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1681\/ASN.V10102185","article-title":"Regulation of aquaporin-1 and nitric oxide synthase isoforms in a rat model of acute peritonitis","volume":"10","author":"Combet","year":"1999","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/sj.ki.5000285_bb0180","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1681\/ASN.V1251036","article-title":"Expression of aquaporin-1 in human peritoneal mesothelial cells and its upregulation by glucose in vitro","volume":"12","author":"Lai","year":"2001","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/sj.ki.5000285_bb0185","doi-asserted-by":"crossref","first-page":"15765","DOI":"10.1074\/jbc.M209980200","article-title":"Hypertonicity-induced aquaporin-1 (AQP1) expression is mediated by the activation of MAPK pathways and hypertonicity-responsive element in the AQP1 gene","volume":"278","author":"Umenishi","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1038\/sj.ki.5000285_bb0190","doi-asserted-by":"crossref","first-page":"8407","DOI":"10.1074\/jbc.273.14.8407","article-title":"Evidence for the presence of aquaporin-3 in human red blood cells","volume":"273","author":"Roudier","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1038\/sj.ki.5000285_bb0195","doi-asserted-by":"crossref","first-page":"22070","DOI":"10.1074\/jbc.271.36.22070","article-title":"Adenovirus-mediated expression of aquaporin-5 in epithelial cells","volume":"271","author":"Delporte","year":"1996","journal-title":"J Biol Chem"},{"key":"10.1038\/sj.ki.5000285_bb0200","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1177\/002215540305100203","article-title":"Computerized quantification of tissue vascularization using high-resolution scanning of whole tumor sections","volume":"51","author":"Chantrain","year":"2003","journal-title":"J Histochem Cytochem"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815517079?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815517079?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:46:59Z","timestamp":1758761219000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815517079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,5]]},"references-count":39,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2006,5]]}},"alternative-id":["S0085253815517079"],"URL":"https:\/\/doi.org\/10.1038\/sj.ki.5000285","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2006,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aquaporin-1 plays an essential role in water permeability and ultrafiltration during peritoneal dialysis","name":"articletitle","label":"Article Title"},{"value":"Kidney International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/sj.ki.5000285","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}