{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T13:03:38Z","timestamp":1792674218711,"version":"4.5.0"},"reference-count":71,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":2958,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2007,11]]},"DOI":"10.1038\/sj.ki.5002439","type":"journal-article","created":{"date-parts":[[2007,8,1]],"date-time":"2007-08-01T05:58:24Z","timestamp":1185947904000},"page":"1057-1064","source":"Crossref","is-referenced-by-count":117,"title":["The Uroepithelial-associated sensory web"],"prefix":"10.1016","volume":"72","author":[{"given":"G.","family":"Apodaca","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Balestreire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.A.","family":"Birder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/sj.ki.5002439_bb0010","first-page":"43","article-title":"\u2018The force be with you\u2019: ATP in gut mechanosensory transduction","volume":"18","author":"Cooke","year":"2003","journal-title":"News Physiol Sci"},{"key":"10.1038\/sj.ki.5002439_bb0015","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/S0165-6147(00)01643-6","article-title":"Purine-mediated signalling in pain and visceral perception","volume":"22","author":"Burnstock","year":"2001","journal-title":"T Pharm Sci"},{"key":"10.1038\/sj.ki.5002439_bb0020","first-page":"F489","article-title":"More than just a barrier: urothelium as a drug target for urinary bladder pain","volume":"289","author":"Birder","year":"2005","journal-title":"Am J Physiol"},{"key":"10.1038\/sj.ki.5002439_bb0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1600-0854.2003.00156.x","article-title":"The uroepithelium: not just a passive barrier","volume":"5","author":"Apodaca","year":"2004","journal-title":"Traffic"},{"key":"10.1038\/sj.ki.5002439_bb0030","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0022-5347(17)39897-X","article-title":"Bladder surface glycosaminoglycans: an epithelial permeability barrier","volume":"143","author":"Parsons","year":"1990","journal-title":"J Urol"},{"key":"10.1038\/sj.ki.5002439_bb0035","first-page":"F886","article-title":"Permeability properties of the intact mammalian bladder epithelium","volume":"271","author":"Negrete","year":"1996","journal-title":"Am J Physiol"},{"key":"10.1038\/sj.ki.5002439_bb0040","first-page":"F305","article-title":"Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium","volume":"287","author":"Acharya","year":"2004","journal-title":"Am J Physiol"},{"key":"10.1038\/sj.ki.5002439_bb0045","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1002\/jcp.20676","article-title":"PPARg-regulated tight junction develoment during human urothelial cytodifferentiation","volume":"208","author":"Varley","year":"2006","journal-title":"J Cell Physiol"},{"key":"10.1038\/sj.ki.5002439_bb0050","first-page":"77","article-title":"The dual function of capsaicin-sensitive sensory nerves in the bladder and urethra","volume":"151","author":"Maggi","year":"1990","journal-title":"Ciba Found Symp"},{"key":"10.1038\/sj.ki.5002439_bb0055","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/ncpuro0672","article-title":"Mechanisms of disease: involvement of the urothelium in bladder dysfunction","volume":"4","author":"Birder","year":"2007","journal-title":"Nature Clin Pract Urol"},{"key":"10.1038\/sj.ki.5002439_bb0060","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s00441-006-0166-8","article-title":"Sensory collaterals, intramural ganglia and motor nerves in the guinea-pig bladder: evidence for intramural neural circuits","volume":"235","author":"Gillespie","year":"2006","journal-title":"Cell Tissue Res"},{"key":"10.1038\/sj.ki.5002439_bb0065","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1038\/ncpuro0340","article-title":"Mechanisms of disease: specialized interstitial cells of the urothelium: an assessment of current knowledge","volume":"2","author":"Brading","year":"2005","journal-title":"Nat Clin Pract Urol"},{"issue":"Part 2","key":"10.1038\/sj.ki.5002439_bb0070","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/j.1469-7793.1997.503bb.x","article-title":"ATP is released from rabbit urinary bladder epithelial cells by hydrostatic pressure changes--a possible sensory mechanism?","volume":"505","author":"Ferguson","year":"1997","journal-title":"J Physiol"},{"key":"10.1038\/sj.ki.5002439_bb0075","doi-asserted-by":"crossref","first-page":"2412","DOI":"10.1172\/JCI24086","article-title":"ATP and purinergic receptor-dependent membrane traffic in bladder umbrella cells","volume":"115","author":"Wang","year":"2005","journal-title":"J Clin Invest"},{"key":"10.1038\/sj.ki.5002439_bb0080","first-page":"F332","article-title":"Kinetics of urothelial ATP release","volume":"291","author":"Lewis","year":"2006","journal-title":"Am J Physiol"},{"key":"10.1038\/sj.ki.5002439_bb0085","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1016\/S0022-5347(01)64198-3","article-title":"Concentrations of specific epithelial growth factors in the urine of interstitial cystitis patients and controls","volume":"158","author":"Keay","year":"1997","journal-title":"J Urol"},{"key":"10.1038\/sj.ki.5002439_bb0090","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.yexcr.2005.02.004","article-title":"Autocrine regulation of human urothelial cell proliferation and migration during regenerative responses in vitro","volume":"306","author":"Varley","year":"2005","journal-title":"Exp Cell Res"},{"key":"10.1038\/sj.ki.5002439_bb0095","doi-asserted-by":"crossref","first-page":"C254","DOI":"10.1152\/ajpcell.00025.2006","article-title":"Adenosine receptor expression and function in bladder uroepithelium","volume":"291","author":"Yu","year":"2006","journal-title":"Am J Physiol"},{"key":"10.1038\/sj.ki.5002439_bb0100","first-page":"F226","article-title":"Adrenergic- and capsaicin-evoked nitric oxide release from urothelium and afferent nerves in urinary bladder","volume":"275","author":"Birder","year":"1998","journal-title":"Am J Physiol"},{"key":"10.1038\/sj.ki.5002439_bb0105","doi-asserted-by":"crossref","first-page":"8063","DOI":"10.1523\/JNEUROSCI.22-18-08063.2002","article-title":"Beta-adrenoceptor agonists stimulate endothelial nitric oxide synthase in rat urinary bladder urothelial cells","volume":"22","author":"Birder","year":"2002","journal-title":"J Neurosci"},{"key":"10.1038\/sj.ki.5002439_bb0110","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1113\/jphysiol.2004.071159","article-title":"Expression and function of bradykinin B1 and B2 receptors in normal and inflamed rat urinary bladder urothelium","volume":"562.3","author":"Chopra","year":"2005","journal-title":"J Physiol"},{"issue":"Suppl 6A","key":"10.1038\/sj.ki.5002439_bb0115","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.urology.2004.08.063","article-title":"The urothelium in overactive bladder: passive bystander or active participant?","volume":"64","author":"De Groat","year":"2004","journal-title":"Urology"},{"key":"10.1038\/sj.ki.5002439_bb0120","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1046\/j.1474-8673.2002.00258.x","article-title":"Muscarinic receptors of the urinary bladder: detrusor, urothelial and prejunctional","volume":"22","author":"Chess-Williams","year":"2002","journal-title":"Auton Autacoid Pharmacol"},{"key":"10.1038\/sj.ki.5002439_bb0125","first-page":"23","article-title":"Expression and function of urothelial muscarinic receptors and interactions with bladder nerves","volume":"846","author":"Beckel","year":"2004","journal-title":"Soc Neurosci Abstr Program"},{"key":"10.1038\/sj.ki.5002439_bb0130","first-page":"1489","article-title":"P2X receptor expression in mouse urinary bladder and the requirement of P2X1 receptors for functional P2X receptor responses in the mouse urinary bladder smooth muscle","volume":"131","author":"Vial","year":"2000"},{"key":"10.1038\/sj.ki.5002439_bb0135","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1159\/000056122","article-title":"Distribution of P2X1 and P2X3 receptors in the rat and human urinary bladder","volume":"63","author":"Elneil","year":"2001","journal-title":"Pharmacology"},{"key":"10.1038\/sj.ki.5002439_bb0140","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1111\/j.1464-410X.2004.04858.x","article-title":"P2X2 and P2X3 receptor expression in human bladder urothelium and changes in interstitial cystitis","volume":"93","author":"Tempest","year":"2004","journal-title":"B J Urol Int"},{"key":"10.1038\/sj.ki.5002439_bb0145","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1016\/S0022-5347(05)67618-5","article-title":"Distribution of P2X receptors in the urinary bladder and the ureter of the rat","volume":"163","author":"Lee","year":"2000","journal-title":"J Urol"},{"key":"10.1038\/sj.ki.5002439_bb0150","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1097\/01.ju.0000099660.46774.3c","article-title":"Upregulation of P2X3 receptor during stretch of bladder urothelial cells from patients with interstitial cystitis","volume":"171","author":"Sun","year":"2004","journal-title":"J Urol"},{"key":"10.1038\/sj.ki.5002439_bb0155","first-page":"F1084","article-title":"Alterations in P2X and P2Y purinergic receptor expression in urinary bladder from normal cats and cats with interstitial cystitis","volume":"287","author":"Birder","year":"2004","journal-title":"Am J Physiol"},{"key":"10.1038\/sj.ki.5002439_bb0160","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/S0002-9440(10)63886-2","article-title":"Expression of protease-activated receptor-1,-2,-3, and -5 in control and experimentally inflamed mouse bladder","volume":"162","author":"D'Andrea","year":"2003","journal-title":"Am J Pathol"},{"key":"10.1038\/sj.ki.5002439_bb0165","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1046\/j.1464-410x.1999.00187.x","article-title":"Urothelial function","volume":"84","author":"Ferguson","year":"1999","journal-title":"B J U Int"},{"key":"10.1038\/sj.ki.5002439_bb0170","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S1046-2023(03)00027-6","article-title":"Analysis of hydrostatic pressure-induced changes in umbrella cell surface area","volume":"30","author":"Wang","year":"2003","journal-title":"Methods"},{"key":"10.1038\/sj.ki.5002439_bb0175","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF01869689","article-title":"Na+ transport by rabbit urinary bladder, a tight epithelium","volume":"28","author":"Lewis","year":"1976","journal-title":"J Membrane Biol"},{"key":"10.1038\/sj.ki.5002439_bb0180","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1038\/nn902","article-title":"Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1","volume":"5","author":"Birder","year":"2002","journal-title":"Nature Neurosci"},{"key":"10.1038\/sj.ki.5002439_bb0185","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1097\/01.ju.0000134880.55119.cf","article-title":"Cool (TRPM8) and hot (TRPV1) receptors in the bladder and male genital tract","volume":"172","author":"Stein","year":"2004","journal-title":"J Urol"},{"key":"10.1038\/sj.ki.5002439_bb0190","doi-asserted-by":"crossref","DOI":"10.1124\/jpet.107.125435","article-title":"Activation of urothelial-Trpv4 by 4alpha-PDD contributes to altered bladder reflexes in the rat","author":"Birder","year":"2007","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1038\/sj.ki.5002439_bb0195","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1091\/mbc.01-09-0435","article-title":"Stretch-regulated exocytosis\/endocytosis in bladder umbrella cells","volume":"13","author":"Truschel","year":"2002","journal-title":"Mol Biol Cell"},{"key":"10.1038\/sj.ki.5002439_bb0200","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0248-4900(00)89018-8","article-title":"The response of junctional complexes to induced desquamation in mouse bladder urothelium","volume":"92","author":"Veranic","year":"2000","journal-title":"Biol Cell"},{"key":"10.1038\/sj.ki.5002439_bb0205","first-page":"F651","article-title":"Hydrostatic pressure-regulated ion transport in bladder uroepithelium","volume":"285","author":"Wang","year":"2003","journal-title":"Am J Physiol"},{"key":"10.1038\/sj.ki.5002439_bb0210","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/BF01868937","article-title":"Apical membrane area of rabbit urinary bladder increases by fusion of intracellular vesicle: an electrophysiological study","volume":"82","author":"Lewis","year":"1984","journal-title":"J Membr Biol"},{"key":"10.1038\/sj.ki.5002439_bb0215","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1091\/mbc.E06-09-0842","article-title":"Apical EGF receptor signaling: regulation of stretch-dependent exocytosis in bladder umbrella cells","volume":"18","author":"Balestreire","year":"2007","journal-title":"Mol Biol Cell"},{"key":"10.1038\/sj.ki.5002439_bb0220","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/379557a0","article-title":"Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors","volume":"379","author":"Daub","year":"1996","journal-title":"Nature"},{"key":"10.1038\/sj.ki.5002439_bb0225","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s00441-005-1151-3","article-title":"Expression of neuronal nitric oxide synthase (nNOS) and nitric-oxide-induced changes in cGM in the urothelial layer of the guinea pig bladder","volume":"321","author":"Gillespie","year":"2005","journal-title":"Cell Tissue Res"},{"key":"10.1038\/sj.ki.5002439_bb0230","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1038\/35039519","article-title":"Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice","volume":"407","author":"Cockayne","year":"2000","journal-title":"Nature"},{"key":"10.1038\/sj.ki.5002439_bb0235","first-page":"F1065","article-title":"Origin of spontaneous activity in neonatal and adult rat bladders and its enhancement by stretch and muscarinic agonists","volume":"292","author":"Kanai","year":"2007","journal-title":"Am J Physiol"},{"key":"10.1038\/sj.ki.5002439_bb0240","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1038\/sj.bjp.0703068","article-title":"Urothelium-derived inhibitory factor(s) influences on detrusor muscle contractility in vitro","volume":"129","author":"Hawthorn","year":"2000","journal-title":"Br J Pharmacol"},{"key":"10.1038\/sj.ki.5002439_bb0245","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1097\/01.ju.0000091870.51841.ae","article-title":"Inhibition of human detrusor contraction by a urothelium derived factor","volume":"170","author":"Chaiyaprasithi","year":"2003","journal-title":"J Urol"},{"key":"10.1038\/sj.ki.5002439_bb0250","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1097\/01.ju.0000108120.28291.eb","article-title":"Electrical characteristics of suburothelial cells isolated from the human bladder","volume":"171","author":"Sui","year":"2004","journal-title":"J Urol"},{"key":"10.1038\/sj.ki.5002439_bb0255","doi-asserted-by":"crossref","first-page":"2298","DOI":"10.1016\/j.lfs.2007.02.010","article-title":"Non-neuronal acetylcholine and urinary bladder urothelium","volume":"80","author":"Hanna-Mitchell","year":"2007","journal-title":"Life Sci"},{"key":"10.1038\/sj.ki.5002439_bb0260","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1016\/j.eururo.2006.10.028","article-title":"Acetylcholine and molecular components of its synthesis and release machinery in the uroepithelium","volume":"51","author":"Lips","year":"2007","journal-title":"Eur Urol"},{"key":"10.1038\/sj.ki.5002439_bb0265","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1046\/j.1464-410x.1999.00310.x","article-title":"Purinergic sensory neurotransmission in the urinary bladder: an in vitro study in the rat","volume":"84","author":"Namasivayam","year":"1999","journal-title":"B J U Int"},{"key":"10.1038\/sj.ki.5002439_bb0270","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1016\/S0022-5347(05)64631-9","article-title":"Intravesical adenosine triphosphate stimulates the mictruition reflex in awake, freely moving rats","volume":"168","author":"Pandita","year":"2002","journal-title":"J Urol"},{"key":"10.1038\/sj.ki.5002439_bb0275","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/j.neuropharm.2004.08.003","article-title":"Activation of ureter nociceptors by exogenous and endogenous ATP in guinea pig","volume":"27","author":"Rong","year":"2004","journal-title":"Neuropharmacol"},{"key":"10.1038\/sj.ki.5002439_bb0280","doi-asserted-by":"crossref","first-page":"5670","DOI":"10.1523\/JNEUROSCI.21-15-05670.2001","article-title":"P2X3 knock-out mice reveal a major sensory role for urothelially released ATP","volume":"21","author":"Vlaskovska","year":"2001","journal-title":"J Neurosci"},{"key":"10.1038\/sj.ki.5002439_bb0285","first-page":"F103","article-title":"Expression and functional nicotinic acetylcholine receptors in bladder epithelial cells","volume":"290","author":"Beckel","year":"2006","journal-title":"Am J Physiol"},{"key":"10.1038\/sj.ki.5002439_bb0290","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.urology.2004.11.021","article-title":"Antimuscarinic agents exhibit local inhibitory effects on muscarinic receptors in bladder afferent pathways","volume":"65","author":"Kim","year":"2004","journal-title":"Urol"},{"key":"10.1038\/sj.ki.5002439_bb0295","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1038\/sj.bjp.0706604","article-title":"Integrative control of the lower urinary tract: preclinical perspective","volume":"147","author":"De Groat","year":"2006","journal-title":"Br J Pharmacol"},{"key":"10.1038\/sj.ki.5002439_bb0300","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/S0022-5347(05)67420-4","article-title":"Intravesicle oxyhemoglobin initiates bladder overactivity in conscious, normal rats","volume":"164","author":"Pandita","year":"2000","journal-title":"J Urol"},{"key":"10.1038\/sj.ki.5002439_bb0305","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1097\/01.ju.0000154631.92150.ef","article-title":"Intravesical resiniferatoxin for the treatment of interstitial cystitis: a randomized, double-blind, placebo controlled trial","volume":"173","author":"Payne","year":"2005","journal-title":"J Urol"},{"key":"10.1038\/sj.ki.5002439_bb0310","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S0022-5347(01)65211-X","article-title":"Desensitization of bladder sensory fibers by intravesical capsaicin has long lasting clinical and urodynamic effects in patients with hyperactive or hpersensitive bladder dysfunction","volume":"157","author":"Cruz","year":"1997","journal-title":"J Urol"},{"key":"10.1038\/sj.ki.5002439_bb0315","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/0140-6736(92)91186-C","article-title":"Intravesical capsaicin for neurogenic bladder dysfunction","volume":"339","author":"Fowler","year":"1992","journal-title":"Lancet"},{"key":"10.1038\/sj.ki.5002439_bb0320","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/j.eururo.2006.04.006","article-title":"Effect of intravesical resiniferatoxin (RTX) on lower urinary tract symptoms, urodynamic parameters, and quality of life of patients with urodynamic increased bladder sensation","volume":"50","author":"Apostolidis","year":"2006","journal-title":"Eur Urol"},{"key":"10.1038\/sj.ki.5002439_bb0325","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1113\/jphysiol.2005.088435","article-title":"P2X2 knockout mice and P2X2\/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating mutiple sensory effects of ATP","volume":"567","author":"Cockayne","year":"2005","journal-title":"J Physiol"},{"key":"10.1038\/sj.ki.5002439_bb0330","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1016\/S0022-5347(05)65726-6","article-title":"Augmented stretch activated adenosine triphosphate release from bladder uroepithelial cells in patients with interstitital cystitis","volume":"166","author":"Sun","year":"2001","journal-title":"J Urol"},{"key":"10.1038\/sj.ki.5002439_bb0335","first-page":"F423","article-title":"Feline interstitial cystitis results in mechanical hypersensitivity and altered ATP release from bladder urothelium","volume":"285","author":"Birder","year":"2003","journal-title":"Am J Physiol"},{"key":"10.1038\/sj.ki.5002439_bb0340","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.neuint.2005.04.021","article-title":"Enhanced ATP release from bladder urothelium during chronic inflammation: effect of botulinum toxin A","volume":"47","author":"Smith","year":"2005","journal-title":"Neurochem Int"},{"key":"10.1038\/sj.ki.5002439_bb0345","doi-asserted-by":"crossref","first-page":"C27","DOI":"10.1152\/ajpcell.00552.2004","article-title":"Augmented extracellular adenosine triphosphate (ATP) signaling in bladder uroepithelial cells from patients with interstitial cystitis","volume":"290","author":"Sun","year":"2005","journal-title":"Am J Physiol"},{"key":"10.1038\/sj.ki.5002439_bb0350","doi-asserted-by":"crossref","first-page":"6951","DOI":"10.1073\/pnas.111025298","article-title":"Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hypersensitivity","volume":"98","author":"Tominaga","year":"2001","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/sj.ki.5002439_bb0355","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.eururo.2003.12.017","article-title":"P2X3-immunoreactive nerve fibers in neurogenic detrusor overactivity and the effect of intravesicle resiniferatoxin","volume":"46","author":"Brady","year":"2004","journal-title":"Eur Urol"},{"key":"10.1038\/sj.ki.5002439_bb0360","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1097\/01.ju.0000169481.42259.54","article-title":"Decreased sensory receptors P2X3 and TRPV1 in suburoethelial nerve fibers following intradetrusor injections of botulinum toxin for human detrusor overactivity","volume":"174","author":"Apostolidis","year":"2005","journal-title":"J Urol"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815527907?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815527907?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T12:38:30Z","timestamp":1556714310000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815527907"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11]]},"references-count":71,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["S0085253815527907"],"URL":"https:\/\/doi.org\/10.1038\/sj.ki.5002439","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2007,11]]}}}