{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T18:03:28Z","timestamp":1782237808019,"version":"3.54.5"},"reference-count":14,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":2837,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2008,3]]},"DOI":"10.1038\/sj.ki.5002798","type":"journal-article","created":{"date-parts":[[2008,2,29]],"date-time":"2008-02-29T12:05:09Z","timestamp":1204286709000},"page":"671-673","source":"Crossref","is-referenced-by-count":6,"title":["It's not all about nephrin"],"prefix":"10.1016","volume":"73","author":[{"given":"M.","family":"Simons","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.B.","family":"Huber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/sj.ki.5002798_bb0010","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/S1097-2765(00)80057-X","article-title":"Positionally cloned gene for a novel glomerular protein\u2014nephrin\u2014is mutated in congenital nephrotic syndrome","volume":"1","author":"Kestil\u00e4","year":"1998","journal-title":"Mol Cell"},{"key":"10.1038\/sj.ki.5002798_bb0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/hmg\/10.1.1","article-title":"The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death","volume":"10","author":"Putaala","year":"2001","journal-title":"Hum Mol Genet"},{"key":"10.1038\/sj.ki.5002798_bb0020","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1097\/01.mnh.0000165885.85803.a8","article-title":"The slit diaphragm: a signaling platform to regulate podocyte function","volume":"14","author":"Huber","year":"2005","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1038\/sj.ki.5002798_bb0025","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1172\/JCI22562","article-title":"Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography","volume":"114","author":"Wartiovaara","year":"2004","journal-title":"J Clin Invest"},{"key":"10.1038\/sj.ki.5002798_bb0030","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1038\/sj.ki.5002707","article-title":"Nephrin is involved in podocyte maturation but not survival during glomerular development","volume":"73","author":"Don\u00e9","year":"2008","journal-title":"Kidney Int"},{"key":"10.1038\/sj.ki.5002798_bb0035","first-page":"F514","article-title":"Increased Tyr phosphorylation of ZO-1 during modification of tight junctions between glomerular foot processes","volume":"268","author":"Kurihara","year":"1995","journal-title":"Am J Physiol"},{"key":"10.1038\/sj.ki.5002798_bb0040","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1038\/nature04662","article-title":"Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes","volume":"440","author":"Jones","year":"2006","journal-title":"Nature"},{"key":"10.1038\/sj.ki.5002798_bb0045","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1172\/JCI27414","article-title":"Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization","volume":"116","author":"Verma","year":"2006","journal-title":"J Clin Invest"},{"key":"10.1038\/sj.ki.5002798_bb0050","doi-asserted-by":"crossref","first-page":"4829","DOI":"10.1128\/MCB.21.14.4829-4836.2001","article-title":"Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN","volume":"21","author":"Donoviel","year":"2001","journal-title":"Mol Cell Biol"},{"key":"10.1038\/sj.ki.5002798_bb0055","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/0896-6273(95)90032-2","article-title":"Restricted expression of the irreC-rst protein is required for normal axonal projections of columnar visual neurons","volume":"15","author":"Schneider","year":"1995","journal-title":"Neuron"},{"key":"10.1038\/sj.ki.5002798_bb0060","doi-asserted-by":"crossref","first-page":"4917","DOI":"10.1128\/MCB.23.14.4917-4928.2003","article-title":"Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling","volume":"23","author":"Huber","year":"2003","journal-title":"Mol Cell Biol"},{"key":"10.1038\/sj.ki.5002798_bb0065","doi-asserted-by":"crossref","first-page":"37004","DOI":"10.1074\/jbc.M403534200","article-title":"A novel role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis","volume":"279","author":"Schiffer","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1038\/sj.ki.5002798_bb0070","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1056\/NEJMra052131","volume":"354","author":"Tryggvason","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1038\/sj.ki.5002798_bb0075","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1146\/annurev.cellbio.22.010305.104340","article-title":"The cellular basis of kidney development","volume":"22","author":"Dressler","year":"2006","journal-title":"Annu Rev Cell Dev Biol"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815530779?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815530779?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T11:13:31Z","timestamp":1626866011000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815530779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,3]]}},"alternative-id":["S0085253815530779"],"URL":"https:\/\/doi.org\/10.1038\/sj.ki.5002798","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2008,3]]}}}