{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T20:09:42Z","timestamp":1790885382538,"version":"4.1.0"},"reference-count":55,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2001,6,1]],"date-time":"2001-06-01T00:00:00Z","timestamp":991353600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2001,6,1]],"date-time":"2001-06-01T00:00:00Z","timestamp":991353600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Leukemia"],"published-print":{"date-parts":[[2001,6,1]]},"DOI":"10.1038\/sj.leu.2402131","type":"journal-article","created":{"date-parts":[[2002,9,19]],"date-time":"2002-09-19T21:05:13Z","timestamp":1032469513000},"page":"921-928","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":66,"title":["In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-\u03baB activity"],"prefix":"10.1038","volume":"15","author":[{"given":"C","family":"Wuchter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Krappmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Ruppert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Scheidereit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"D\u00f6rken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W-D","family":"Ludwig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Karawajew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2001,7,5]]},"reference":[{"key":"BF2402131_CR1","doi-asserted-by":"publisher","first-page":"1833","DOI":"10.1038\/sj.leu.2401902","volume":"14","author":"E Solary","year":"2000","unstructured":"Solary E, Droin N, Bettaieb A, Corcos L, Dimanche Boitrel MT, Garrido C . Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies Leukemia 2000 14: 1833\u20131849","journal-title":"Leukemia"},{"key":"BF2402131_CR2","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1006\/excr.2000.4838","volume":"256","author":"SH Kaufmann","year":"2000","unstructured":"Kaufmann SH, Earnshaw WC . Induction of apoptosis by cancer chemotherapy Exp Cell Res 2000 256: 42\u201349","journal-title":"Exp Cell Res"},{"key":"BF2402131_CR3","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1097\/00001622-199911000-00008","volume":"11","author":"JA Houghton","year":"1999","unstructured":"Houghton JA . Apoptosis and drug response Curr Opin Oncol 1999 11: 475\u2013481","journal-title":"Curr Opin Oncol"},{"key":"BF2402131_CR4","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/S0955-0674(99)80034-9","volume":"11","author":"A Ashkenazi","year":"1999","unstructured":"Ashkenazi A, Dixit VM . Apoptosis control by death and decoy receptors Curr Opin Cell Biol 1999 11: 255\u2013260","journal-title":"Curr Opin Cell Biol"},{"key":"BF2402131_CR5","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1016\/S0952-7915(98)80224-0","volume":"10","author":"TS Griffith","year":"1998","unstructured":"Griffith TS, Lynch DH . TRAIL: a molecule with multiple receptors and control mechanisms Curr Opin Immunol 1998 10: 559\u2013563","journal-title":"Curr Opin Immunol"},{"key":"BF2402131_CR6","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1038\/5517","volume":"5","author":"H Walczak","year":"1999","unstructured":"Walczak H, Miller RE, Ariail K, Gliniak B, Griffith TS, Kubin M, Chin W, Jones J, Woodward A, Le T, Smith C, Smolak P, Goodwin RG, Rauch CT, Schuh JC, Lynch DH . Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo Nat Med 1999 5: 157\u2013163","journal-title":"Nat Med"},{"key":"BF2402131_CR7","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1172\/JCI6926","volume":"104","author":"A Ashkenazi","year":"1999","unstructured":"Ashkenazi A, Pai RC, Fong S, Leung S, Lawrence DA, Marsters SA, Blackie C, Chang L, McMurtrey AE, Hebert A, DeForge L, Koumenis IL, Lewis D, Harris L, Bussiere J, Koeppen H, Shahrokh Z, Schwall RH . Safety and antitumor activity of recombinant soluble Apo2 ligand J Clin Invest 1999 104: 155\u2013162","journal-title":"J Clin Invest"},{"key":"BF2402131_CR8","first-page":"847","volume":"60","author":"M Nagane","year":"2000","unstructured":"Nagane M, Pan GH, Weddle JJ, Dixit VM, Cavenee WK, Huang HJS . Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo Cancer Res 2000 60: 847\u2013853","journal-title":"Cancer Res"},{"key":"BF2402131_CR9","first-page":"6153","volume":"59","author":"B Gliniak","year":"1999","unstructured":"Gliniak B, Le T . Tumor necrosis factor-related apoptosis-inducing ligand's antitumor activity in vivo is enhanced by the chemotherapeutic agent CPT-11 Cancer Res 1999 59: 6153\u20136158","journal-title":"Cancer Res"},{"key":"BF2402131_CR10","first-page":"335","volume":"6","author":"KH Kim","year":"2000","unstructured":"Kim KH, Fisher MJ, Xu SQ, El Deiry WS . Molecular determinants of response to TRAIL in killing of normal and cancer cells Clin Cancer Res 2000 6: 335\u2013346","journal-title":"Clin Cancer Res"},{"key":"BF2402131_CR11","first-page":"734","volume":"59","author":"MM Keane","year":"1999","unstructured":"Keane MM, Ettenberg SA, Nau MM, Russell EK, Lipkowitz S . Chemotherapy augments TRAIL-induced apoptosis in breast cell lines Cancer Res 1999 59: 734\u2013741","journal-title":"Cancer Res"},{"key":"BF2402131_CR12","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1038\/75045","volume":"6","author":"M Jo","year":"2000","unstructured":"Jo M, Kim T-H, Seol D-W, Esplen J, Dorko K, Billiar T, Strom S . Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand Nat Med 2000 6: 654\u2013657","journal-title":"Nat Med"},{"key":"BF2402131_CR13","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1016\/S0140-6736(00)02659-3","volume":"356","author":"R Nitsch","year":"2000","unstructured":"Nitsch R, Bechmann I, Deisz RA, Haas D, Lehmann TN, Wendling U, Zipp F . Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL) Lancet 2000 356: 827\u2013828","journal-title":"Lancet"},{"key":"BF2402131_CR14","first-page":"3716","volume":"95","author":"L Zamai","year":"2000","unstructured":"Zamai L, Secchiero P, Pierpaoli S, Bassini A, Papa S, Alnemri ES, Guidotti L, Vitale M, Zauli G . TNF-related apoptosis-inducing ligand (TRAIL) as a negative regulator of normal human erythropoiesis Blood 2000 95: 3716\u20133724","journal-title":"Blood"},{"key":"BF2402131_CR15","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.1038\/sj.leu.2401865","volume":"14","author":"MS Sheikh","year":"2000","unstructured":"Sheikh MS, Fornace AJ Jr . Death and decoy receptors and p53-mediated apoptosis Leukemia 2000 14: 1509\u20131513","journal-title":"Leukemia"},{"key":"BF2402131_CR16","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1128\/MCB.20.1.205-212.2000","volume":"20","author":"SB Gibson","year":"2000","unstructured":"Gibson SB, Oyer R, Spalding AC, Anderson SM, Johnson GL . Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL Mol Cell Biol 2000 20: 205\u2013212","journal-title":"Mol Cell Biol"},{"key":"BF2402131_CR17","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1046\/j.1365-2141.2000.02404.x","volume":"111","author":"K Clodi","year":"2000","unstructured":"Clodi K, Wimmer D, Li Y, Goodwin R, Jaeger U, Mann G, Gadner H, Younes A . Expression of tumour necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptors and sensitivity to TRAIL-induced apoptosis in primary B-cell acute lymphoblastic leukaemia cells Br J Haematol 2000 111: 580\u2013586","journal-title":"Br J Haematol"},{"key":"BF2402131_CR18","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1046\/j.1365-2141.1997.4393250.x","volume":"99","author":"V Snell","year":"1997","unstructured":"Snell V, Clodi K, Zhao S, Goodwin R, Thomas EK, Morris SW, Kadin ME, Cabanillas F, Andreeff M, Younes A . Activity of TNF-related apoptosis-inducing ligand (TRAIL) in haematological malignancies Br J Haematol 1997 99: 618\u2013624","journal-title":"Br J Haematol"},{"key":"BF2402131_CR19","doi-asserted-by":"publisher","first-page":"1010","DOI":"10.1006\/cyto.1999.0536","volume":"11","author":"Y Gazitt","year":"1999","unstructured":"Gazitt Y, Shaughnessy P, Montgomery W . Apoptosis-induced by trail and TNF-alpha in human multiple myeloma cells is not blocked by bcl-2 Cytokine 1999 11: 1010\u20131019","journal-title":"Cytokine"},{"key":"BF2402131_CR20","doi-asserted-by":"publisher","first-page":"1817","DOI":"10.1038\/sj.leu.2401501","volume":"13","author":"Y Gazitt","year":"1999","unstructured":"Gazitt Y . TRAIL is a potent inducer of apoptosis in myeloma cells derived from multiple myeloma patients and is not cytotoxic to hematopoietic stem cells Leukemia 1999 13: 1817\u20131824","journal-title":"Leukemia"},{"key":"BF2402131_CR21","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1046\/j.1365-2141.1999.01630.x","volume":"106","author":"S Zhao","year":"1999","unstructured":"Zhao S, Asgary Z, Wang Y, Goodwin R, Andreeff M, Younes A . Functional expression of TRAIL by lymphoid and myeloid tumour cells Br J Haematol 1999 106: 827\u2013832","journal-title":"Br J Haematol"},{"key":"BF2402131_CR22","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1038\/sj.cdd.4400727","volume":"7","author":"K Shiiki","year":"2000","unstructured":"Shiiki K, Yoshikawa H, Kinoshita H, Takeda M, Ueno A, Nakajima Y, Tasaka K . Potential mechanisms of resistance to TRAIL\/Apo2L-induced apoptosis in human promyelocytic leukemia HL-60 cells during granulocytic differentiation Cell Death Differ 2000 7: 939\u2013946","journal-title":"Cell Death Differ"},{"key":"BF2402131_CR23","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.1084\/jem.191.7.1095","volume":"191","author":"K Song","year":"2000","unstructured":"Song K, Chen Y, Goke R, Wilmen A, Seidel C, Goke A, Hilliard B . Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progression J Exp Med 2000 191: 1095\u20131104","journal-title":"J Exp Med"},{"key":"BF2402131_CR24","doi-asserted-by":"publisher","first-page":"2897","DOI":"10.4049\/jimmunol.164.6.2897","volume":"164","author":"MJ Kaplan","year":"2000","unstructured":"Kaplan MJ, Ray D, Mo RR, Yung RL, Richardson BC . TRAIL (Apo2 ligand) and TWEAK (Apo3 ligand) mediate CD4+ T cell killing of antigen-presenting macrophages J Immunol 2000 164: 2897\u20132904","journal-title":"J Immunol"},{"key":"BF2402131_CR25","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1084\/jem.190.8.1155","volume":"190","author":"NA Fanger","year":"1999","unstructured":"Fanger NA, Maliszewski CR, Schooley K, Griffith TS . Human dendritic cells mediate cellular apoptosis via tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) J Exp Med 1999 190: 1155\u20131164","journal-title":"J Exp Med"},{"key":"BF2402131_CR26","doi-asserted-by":"publisher","first-page":"2714","DOI":"10.1002\/(SICI)1521-4141(199809)28:09<2714::AID-IMMU2714>3.0.CO;2-9","volume":"28","author":"MJ Martinez Lorenzo","year":"1998","unstructured":"Martinez Lorenzo MJ, Alava MA, Gamen S, Kim KJ, Chuntharapai A, Pineiro A, Naval J, Anel A . Involvement of APO2 ligand\/TRAIL in activation-induced death of Jurkat and human peripheral blood T cells Eur J Immunol 1998 28: 2714\u20132725","journal-title":"Eur J Immunol"},{"key":"BF2402131_CR27","doi-asserted-by":"crossref","first-page":"4624","DOI":"10.1182\/blood.V91.12.4624","volume":"91","author":"I Jeremias","year":"1998","unstructured":"Jeremias I, Kupatt C, Baumann B, Herr I, Wirth T, Debatin KM . Inhibition of nuclear factor kappaB activation attenuates apoptosis resistance in lymphoid cells Blood 1998 91: 4624\u20134631","journal-title":"Blood"},{"key":"BF2402131_CR28","doi-asserted-by":"crossref","first-page":"3900","DOI":"10.1182\/blood.V96.12.3900","volume":"96","author":"J Wen","year":"2000","unstructured":"Wen J, Ramadevi N, Nguyen D, Perkins C, Worthington E, Bhalla H . Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells Blood 2000 96: 3900\u20133906","journal-title":"Blood"},{"key":"BF2402131_CR29","doi-asserted-by":"publisher","first-page":"620","DOI":"10.7326\/0003-4819-103-4-620","volume":"103","author":"JM Bennett","year":"1985","unstructured":"Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DA, Gralnick HR, Sultan C . Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French\u2013American\u2013British Cooperative Group Ann Intern Med 1985 103: 620\u2013625","journal-title":"Ann Intern Med"},{"key":"BF2402131_CR30","first-page":"1783","volume":"9","author":"MC B\u00e9n\u00e9","year":"1995","unstructured":"B\u00e9n\u00e9 MC, Castoldi G, Knapp W, Ludwig WD, Matutes E, Orfao A, van't Veer MB . Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL) Leukemia 1995 9: 1783\u20131786","journal-title":"Leukemia"},{"key":"BF2402131_CR31","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1182\/blood.V92.2.596","volume":"92","author":"MC B\u00e9n\u00e9","year":"1998","unstructured":"B\u00e9n\u00e9 MC, Bernier M, Casasnovas RO, Castoldi G, Knapp W, Lanza F, Ludwig WD, Matutes E, Orfao A, Sperling C, van't Veer MB . The reliability and specificity of c-kit for the diagnosis of acute myeloid leukemias and undifferentiated leukemias. The European Group for the Immunological Classification of Leukemias (EGIL) Blood 1998 92: 596\u2013599","journal-title":"Blood"},{"key":"BF2402131_CR32","doi-asserted-by":"crossref","first-page":"3097","DOI":"10.1182\/blood.V86.8.3097.3097","volume":"86","author":"U Creutzig","year":"1995","unstructured":"Creutzig U, Harbott J, Sperling C, Ritter J, Zimmermann M, L\u00f6ffler H, Riehm H, Schellong G, Ludwig WD . Clinical significance of surface antigen expression in children with acute myeloid leukemia: results of study AML-BFM-87 Blood 1995 86: 3097\u20133108","journal-title":"Blood"},{"key":"BF2402131_CR33","first-page":"1898","volume":"92","author":"WD Ludwig","year":"1998","unstructured":"Ludwig WD, Rieder H, Bartram CR, Heinze B, Schwartz S, Gassmann W, L\u00f6ffler H, Hossfeld D, Heil G, Handt S, Heyll A, Diedrich H, Fischer K, Weiss A, Volkers B, Aydemir U, Fonatsch C, G\u00f6kbuget N, Thiel E, Hoelzer D . Immunophenotypic and genotypic features, clinical characteristics, and treatment outcome of adult pro-B acute lymphoblastic leukemia: results of the German multicenter trials GMALL 03\/87 and 04\/89 Blood 1998 92: 1898\u20131909","journal-title":"Blood"},{"key":"BF2402131_CR34","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1038\/sj.leu.2400746","volume":"11","author":"L Karawajew","year":"1997","unstructured":"Karawajew L, Wuchter C, Ruppert V, Drexler H, Gruss HJ, D\u00f6rken B, Ludwig WD . Differential CD95 expression and function in T and B lineage acute lymphoblastic leukemia cells Leukemia 1997 11: 1245\u20131252","journal-title":"Leukemia"},{"key":"BF2402131_CR35","doi-asserted-by":"publisher","first-page":"1943","DOI":"10.1038\/sj.leu.2401605","volume":"13","author":"C Wuchter","year":"1999","unstructured":"Wuchter C, Karawajew L, Ruppert V, B\u00fcchner T, Schoch C, Ratei R, D\u00f6rken B, Ludwig W-D . Clinical significance of CD95, Bcl-2 and Bax expression in adult de novo acute myeloid leukemia in context of P-glycoprotein function, maturational stage, and cytogenetics Leukemia 1999 13: 1943\u20131953","journal-title":"Leukemia"},{"key":"BF2402131_CR36","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1182\/blood.V96.1.297","volume":"96","author":"L Karawajew","year":"2000","unstructured":"Karawajew L, Ruppert V, Wuchter C, K\u00f6sser A, Schrappe M, D\u00f6rken B, Ludwig W-D . Inhibition of in vitro spontaneous apoptosis by Il-7 correlates with upregulation of Bcl-2, cortical\/mature phenotype, and better early cytoreduction in childhood T-ALL Blood 2000 96: 297\u2013306","journal-title":"Blood"},{"key":"BF2402131_CR37","doi-asserted-by":"publisher","first-page":"1502","DOI":"10.1038\/sj.leu.2401864","volume":"14","author":"MV Blagosklonny","year":"2000","unstructured":"Blagosklonny MV . Cell death beyond apoptosis Leukemia 2000 14: 1502\u20131508","journal-title":"Leukemia"},{"key":"BF2402131_CR38","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1038\/sj.leu.2401705","volume":"14","author":"U Kordes","year":"2000","unstructured":"Kordes U, Krappmann D, Heissmeyer V, Ludwig WD, Scheidereit C . Transcription factor NF-kappa B is constitutively activated in acute lymphoblastic leukemia cells Leukemia 2000 14: 399\u2013402","journal-title":"Leukemia"},{"key":"BF2402131_CR39","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1046\/j.1365-2141.2000.02147.x","volume":"110","author":"C Wuchter","year":"2000","unstructured":"Wuchter C, Karawajew L, Ruppert V, Schrappe M, Harbott J, Ratei R, D\u00f6rken B, Ludwig W-D . Constitutive expression levels of CD95 and Bcl-2 as well as CD95 function and spontaneous apoptosis in vitro do not predict response to induction chemotherapy and relapse rate in childhood ALL Br J Haematol 2000 110: 154\u2013160","journal-title":"Br J Haematol"},{"key":"BF2402131_CR40","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1002\/(SICI)1521-4141(199801)28:01<143::AID-IMMU143>3.0.CO;2-3","volume":"28","author":"I Jeremias","year":"1998","unstructured":"Jeremias I, Herr I, Boehler T, Debatin KM . TRAIL\/Apo-2-ligand-induced apoptosis in human T cells Eur J Immunol 1998 28: 143\u2013152","journal-title":"Eur J Immunol"},{"key":"BF2402131_CR41","doi-asserted-by":"publisher","first-page":"30603","DOI":"10.1074\/jbc.274.43.30603","volume":"274","author":"WH Hu","year":"1999","unstructured":"Hu WH, Johnson H, Shu HB . Tumor necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways J Biol Chem 1999 274: 30603\u201330610","journal-title":"J Biol Chem"},{"key":"BF2402131_CR42","first-page":"553","volume":"60","author":"M Leverkus","year":"2000","unstructured":"Leverkus M, Neumann M, Mengling T, Rauch CT, Brocker EB, Krammer PH, Walczak H . Regulation of tumor necrosis factor-related apoptosis-inducing ligand sensitivity in primary and transformed human keratinocytes Cancer Res 2000 60: 553\u2013559","journal-title":"Cancer Res"},{"key":"BF2402131_CR43","doi-asserted-by":"crossref","first-page":"2597","DOI":"10.4049\/jimmunol.162.5.2597","volume":"162","author":"TS Griffith","year":"1999","unstructured":"Griffith TS, Rauch CT, Smolak PJ, Waugh JY, Boiani N, Lynch DH, Smith CA, Goodwin RG, Kubin MZ . Functional analysis of TRAIL receptors using monoclonal antibodies J Immunol 1999 162: 2597\u20132605","journal-title":"J Immunol"},{"key":"BF2402131_CR44","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1006\/bbrc.2000.3673","volume":"277","author":"IK Kim","year":"2000","unstructured":"Kim IK, Chung CW, Woo HN, Hong GS, Nagata S, Jung YK . Reconstitution of caspase-8 sensitizes JB6 cells to TRAIL Biochem Biophys Res Commun 2000 277: 311\u2013316","journal-title":"Biochem Biophys Res Commun"},{"key":"BF2402131_CR45","first-page":"3051","volume":"60","author":"H Walczak","year":"2000","unstructured":"Walczak H, Bouchon A, Stahl H, Krammer PH . Tumor necrosis factor-related apoptosis-inducing ligand retains its apoptosis-inducing capacity on Bcl-2-or Bcl-x(L)-overexpressing chemotherapy-resistant tumor cells Cancer Res 2000 60: 3051\u20133057","journal-title":"Cancer Res"},{"key":"BF2402131_CR46","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1016\/S1074-7613(00)80212-5","volume":"12","author":"FC Kischkel","year":"2000","unstructured":"Kischkel FC, Lawrence DA, Chuntharapai A, Schow P, Kim KJ, Ashkenazi A . Apo2L\/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5 Immunity 2000 12: 611\u2013620","journal-title":"Immunity"},{"key":"BF2402131_CR47","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1083\/jcb.144.5.891","volume":"144","author":"S Desagher","year":"1999","unstructured":"Desagher S, Osen Sand A, Nichols A, Eskes R, Montessuit S, Lauper S, Maundrell K, Antonsson B, Martinou JC . Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis J Cell Biol 1999 144: 891\u2013901","journal-title":"J Cell Biol"},{"key":"BF2402131_CR48","doi-asserted-by":"publisher","first-page":"2035","DOI":"10.1038\/sj.leu.2401940","volume":"14","author":"PT Daniel","year":"2000","unstructured":"Daniel PT . Dissecting the pathways to death Leukemia 2000 14: 2035\u20132044","journal-title":"Leukemia"},{"key":"BF2402131_CR49","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1007\/s001090050078","volume":"74","author":"FG Wulczyn","year":"1996","unstructured":"Wulczyn FG, Krappmann D, Scheidereit C . The NF-kappa B\/Rel and I kappa B gene families: mediators of immune response and inflammation J Mol Med 1996 74: 749\u201369","journal-title":"J Mol Med"},{"key":"BF2402131_CR50","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1006\/scbi.1997.0061","volume":"8","author":"I Luque","year":"1997","unstructured":"Luque I, Gelinas C . Rel\/NF-kappa B and I kappa B factors in oncogenesis Semin Cancer Biol 1997 8: 103\u2013111","journal-title":"Semin Cancer Biol"},{"key":"BF2402131_CR51","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1126\/science.274.5288.784","volume":"274","author":"CY Wang","year":"1996","unstructured":"Wang CY, Mayo MW, Baldwin AS Jr . TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB Science 1996 274: 784\u2013787","journal-title":"Science"},{"key":"BF2402131_CR52","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1126\/science.274.5288.782","volume":"274","author":"AA Beg","year":"1996","unstructured":"Beg AA, Baltimore D . An essential role for NF-kappaB in preventing TNF-alpha-induced cell death Science 1996 274: 782\u2013784","journal-title":"Science"},{"key":"BF2402131_CR53","doi-asserted-by":"publisher","first-page":"1680","DOI":"10.1126\/science.281.5383.1680","volume":"281","author":"CY Wang","year":"1998","unstructured":"Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr . NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation Science 1998 281: 1680\u20131683","journal-title":"Science"},{"key":"BF2402131_CR54","first-page":"687","volume":"9","author":"I Jeremias","year":"1998","unstructured":"Jeremias I, Debatin KM . TRAIL induces apoptosis and activation of NFkappaB Eur Cytokine Netw 1998 9: 687\u2013688","journal-title":"Eur Cytokine Netw"},{"key":"BF2402131_CR55","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/S0171-2985(97)80022-8","volume":"198","author":"D Krappmann","year":"1997","unstructured":"Krappmann D, Scheidereit C . Regulation of NF-kappa B activity by I kappa B alpha and I kappa B beta stability Immunobiology 1997 198: 3\u201313","journal-title":"Immunobiology"}],"container-title":["Leukemia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/2402131.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/2402131","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/2402131.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T17:19:51Z","timestamp":1682356791000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/2402131"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,6,1]]},"references-count":55,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2001,6,1]]}},"alternative-id":["BF2402131"],"URL":"https:\/\/doi.org\/10.1038\/sj.leu.2402131","relation":{},"ISSN":["0887-6924","1476-5551"],"issn-type":[{"value":"0887-6924","type":"print"},{"value":"1476-5551","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,6,1]]},"assertion":[{"value":"11 September 2000","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 February 2001","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 July 2001","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}