{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:42:39Z","timestamp":1790901759336,"version":"4.1.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2003,9,1]],"date-time":"2003-09-01T00:00:00Z","timestamp":1062374400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2003,9,1]],"date-time":"2003-09-01T00:00:00Z","timestamp":1062374400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Leukemia"],"published-print":{"date-parts":[[2003,9,1]]},"DOI":"10.1038\/sj.leu.2403061","type":"journal-article","created":{"date-parts":[[2003,9,11]],"date-time":"2003-09-11T14:47:26Z","timestamp":1063291646000},"page":"1851-1857","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":64,"title":["t(5;14)\/HOX11L2-positive T-cell acute lymphoblastic leukemia. A collaborative study of the Groupe Fran\u00e7ais de Cytog\u00e9n\u00e9tique H\u00e9matologique (GFCH)"],"prefix":"10.1038","volume":"17","author":[{"given":"R","family":"Berger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Dastugue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Busson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"van den Akker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"P\u00e9rot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Ballerini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Hagemeijer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Michaux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Charrin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M P","family":"Pages","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Mugneret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Andrieux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Talmant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"H\u00e9lias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Mauvieux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Lafage-Pochitaloff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M-J","family":"Mozziconacci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Cornillet-Lefebvre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Radford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Asnafi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Bilhou-Nabera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Nguyen Khac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"L\u00e9onard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Speleman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Poppe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Bastard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Taviaux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Quilichini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Herens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M-J","family":"Gr\u00e9goire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Cav\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O A","family":"Bernard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the Groupe Fran\u00e7ais de Cytog\u00e9n\u00e9tique H\u00e9matologique (GFCH)","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2003,9,10]]},"reference":[{"key":"BF2403061_CR1","doi-asserted-by":"crossref","first-page":"3662","DOI":"10.1182\/blood.V85.12.3662.bloodjournal85123662","volume":"85","author":"SP Romana","year":"1995","unstructured":"Romana SP, Mauchauff\u00e9 M, Le Coniat M, Chumakov I, Le Paslier D, Berger R et al. The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion. Blood 1995; 85: 3662\u20133670.","journal-title":"Blood"},{"key":"BF2403061_CR2","first-page":"773","volume":"94","author":"RJ Jaju","year":"1999","unstructured":"Jaju RJ, Haas OA, Neat M, Harbott J, Saha V, Boultwood J et al. A new recurrent translocation, t(5;11)(q35;p15.5), associated with del(5q) in childhood acute myeloid leukemia. Blood 1999; 94: 773\u2013780.","journal-title":"Blood"},{"key":"BF2403061_CR3","doi-asserted-by":"publisher","first-page":"1495","DOI":"10.1038\/sj.leu.2402249","volume":"15","author":"OA Bernard","year":"2001","unstructured":"Bernard OA, Busson-Le Coniat M, Ballerini P, Mauchauff\u00e9 M, Della Valle V, Monni R et al. A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia. Leukemia 2001; 15: 1495\u20131504.","journal-title":"Leukemia"},{"key":"BF2403061_CR4","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1038\/sj.leu.2402347","volume":"16","author":"C H\u00e9lias","year":"2002","unstructured":"H\u00e9lias C, Leymarie V, Entz-Werle N, Falkenrodt A, Eyer D, Aurich-Costa J et al. Translocation t(5;14)(q35;q32) in 3 cases of childhood T-cell acute lymphoblastic leukemia: a new recurring and cryptic abnormality. Leukemia 2002; 16: 7\u201312.","journal-title":"Leukemia"},{"key":"BF2403061_CR5","doi-asserted-by":"crossref","first-page":"2996","DOI":"10.1182\/blood.V78.11.2996.2996","volume":"78","author":"ID Dub\u00e9","year":"1991","unstructured":"Dub\u00e9 ID, Kamel-Reid S, Yuan CC, Lu M, Wu X, Corpus G et al. A novel homeobox gene lies at the chromosome 10 breakpoint in lymphoid neoplasias with chromosomal translocation t(10;14). Blood 1991; 78: 2996\u20133003.","journal-title":"Blood"},{"key":"BF2403061_CR6","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1126\/science.1676542","volume":"253","author":"M Hatano","year":"1991","unstructured":"Hatano M, Roberts CW, Minden M, Crist WM, Korsmeyer SJ . Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia. Science 1991; 253: 79\u201382.","journal-title":"Science"},{"key":"BF2403061_CR7","doi-asserted-by":"publisher","first-page":"2257","DOI":"10.1038\/sj.leu.2401960","volume":"14","author":"E Vilmer","year":"2000","unstructured":"Vilmer E, Suciu S, Ferster A, Bertrand Y, Cav\u00e9 H, Thyss A et al. Long-term results of three randomized trials (58831, 58832, 58881) in childhood acute lymphoblastic leukemia: a CLCG-EORTC report. Leukemia 2000; 14: 2257\u20132266.","journal-title":"Leukemia"},{"key":"BF2403061_CR8","doi-asserted-by":"publisher","first-page":"1617","DOI":"10.1054\/bjoc.2000.1504","volume":"83","author":"J Donadieu","year":"2000","unstructured":"Donadieu J, Auclerc MF, Baruchel A, Perel Y, Bordigoni P, Landman-Parker J et al. Prognostic study of continuous variables (white blood cell count, peripheral blast cell count, haemoglobin level, platelet count and age) in childhood acute lymphoblastic leukaemia. Analysis of a population of 1545 children treated by the French Acute Lymphoblastic Leukaemia Group (FRALLE). Br J Cancer 2000; 83: 1617\u20131622.","journal-title":"Br J Cancer"},{"key":"BF2403061_CR9","doi-asserted-by":"publisher","first-page":"2057","DOI":"10.1182\/blood-2002-03-0704","volume":"100","author":"H Dombret","year":"2002","unstructured":"Dombret H, Gabert J, Boiron J-M, Rigal-Huret F, Blaise D, Thomas X et al. Outcome of treatment in adults with Philadelphia chromosome-positive acute lymphoblastic leukemia \u2013 results of the prospective multicenter LALA-94 trial. Blood 2002; 100: 2057\u20132066.","journal-title":"Blood"},{"key":"BF2403061_CR10","first-page":"1783","volume":"9","author":"MC Bene","year":"1995","unstructured":"European Group for the Immunological Characterization of Leukemias. (EGIL): Bene MC, Castoldi G, Knapp W, Ludwig WD, Matutes E, Orfao A, van't Veer MB . Proposals for the immunological classification of acute leukemias. Leukemia 1995; 9: 1783\u20131786.","journal-title":"Leukemia"},{"key":"BF2403061_CR11","unstructured":"ISCN 1995. An International System for Human Cytogenetic Nomenclature. In: Mitelman F (ed). Basel, Switzerland: Karger, 1995."},{"key":"BF2403061_CR12","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1182\/blood-2001-11-0093","volume":"100","author":"P Ballerini","year":"2002","unstructured":"Ballerini P, Blaise A, Busson-Le Coniat M, Su X-Y, Zucman-Rossi J, Adam M et al. Hox11L2 expression defines a clinical subtype of pediatrc T-ALL associated with poor prognostic. Blood 2002; 100: 991\u2013997.","journal-title":"Blood"},{"key":"BF2403061_CR13","doi-asserted-by":"publisher","first-page":"2417","DOI":"10.1038\/sj.leu.2402709","volume":"16","author":"L Mauvieux","year":"2002","unstructured":"Mauvieux L, Leymarie V, Helias C, Perusson N, Falkenrodt A, Lioure B et al. High incidence of HOX11L2 expression in children with T-ALL. Leukemia 2002; 16: 2417\u20132422.","journal-title":"Leukemia"},{"key":"BF2403061_CR14","first-page":"1539","volume":"8","author":"JA Whitlock","year":"1994","unstructured":"Whitlock JA, Raimondi SC, Harbott J, Morris SW, McCurley TL, Hansen-Hagge TE et al. t(5;14)(q33-34;q11), a new recurring cytogenetic abnormality in childhood acute leukemia. Leukemia 1994; 8: 1539\u20131543.","journal-title":"Leukemia"},{"key":"BF2403061_CR15","first-page":"22205","volume":"16","author":"TE Hansen-Haage","year":"2002","unstructured":"Hansen-Haage TE, Sch\u00e4fer M, Kiyoi H, Morris SW, Whitlock JA, Koch P et al. Disruption of the RanbBP17\/Hox11L2 region by recombination with the TCRd locus in acute lymphoblastic leukemias with t(5;14)(q34;q11). Leukemia 2002; 16: 22205\u201322212.","journal-title":"Leukemia"},{"key":"BF2403061_CR16","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1182\/blood.V93.5.1443","volume":"93","author":"CG Begley","year":"1999","unstructured":"Begley CG, Green AR . The SCL gene: from case report to critical hematopoietic regulator. Blood 1999; 93: 1760\u20131770.","journal-title":"Blood"},{"key":"BF2403061_CR17","first-page":"1917","volume":"55","author":"PD Aplan","year":"1995","unstructured":"Aplan PD, Johnson BE, Russell E, Chervinsky DS, Kirsch IR . Cloning and characterization of TCTA, a gene located at the site of a t(1;3) translocation. Cancer Res 1995; 55: 1917\u20131921.","journal-title":"Cancer Res"},{"key":"BF2403061_CR18","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/S1535-6108(02)00018-1","volume":"1","author":"AA Ferrando","year":"2002","unstructured":"Ferrando AA, Neuberg DS, Staunton J, Loh ML, Huard C, Raimondi SC et al. Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell 2002; 1: 75\u201387.","journal-title":"Cancer Cell"}],"container-title":["Leukemia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/2403061.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/2403061","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/2403061.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T01:54:50Z","timestamp":1648778090000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/2403061"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,9,1]]},"references-count":18,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2003,9,1]]}},"alternative-id":["BF2403061"],"URL":"https:\/\/doi.org\/10.1038\/sj.leu.2403061","relation":{},"ISSN":["0887-6924","1476-5551"],"issn-type":[{"value":"0887-6924","type":"print"},{"value":"1476-5551","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,9,1]]},"assertion":[{"value":"2 April 2003","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 May 2003","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 September 2003","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}