{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:39:43Z","timestamp":1790739583572,"version":"4.1.0"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2004,10,7]],"date-time":"2004-10-07T00:00:00Z","timestamp":1097107200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2004,10,7]],"date-time":"2004-10-07T00:00:00Z","timestamp":1097107200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Leukemia"],"published-print":{"date-parts":[[2004,12,1]]},"DOI":"10.1038\/sj.leu.2403485","type":"journal-article","created":{"date-parts":[[2004,10,7]],"date-time":"2004-10-07T09:55:30Z","timestamp":1097142930000},"page":"2015-2025","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["TGF\u03b2-mediated activation of Smad1 in B-cell non-Hodgkin's lymphoma and effect on cell proliferation"],"prefix":"10.1038","volume":"18","author":[{"given":"O","family":"Munoz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Fend","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"de Beaumont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Husson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Astier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A S","family":"Freedman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2004,10,7]]},"reference":[{"key":"BF2403485_CR1","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1056\/NEJM197404112901501","volume":"290","author":"ES Jaffe","year":"1974","unstructured":"Jaffe ES, Shevach EM, Frank MM, Berard CW, Green I . Nodular lymphoma \u2013 evidence for origin from follicular B lymphocytes. N Engl J Med 1974; 290: 813\u2013819.","journal-title":"N Engl J Med"},{"key":"BF2403485_CR2","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/0092-8674(93)80066-N","volume":"75","author":"DM Hockenbery","year":"1993","unstructured":"Hockenbery DM, Oltvai ZN, Yin X-M, Milliman CL, Korsmeyer SJ . Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993; 75: 241\u2013251.","journal-title":"Cell"},{"key":"BF2403485_CR3","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.1126\/science.3874430","volume":"228","author":"Y Tsujimoto","year":"1985","unstructured":"Tsujimoto Y, Cossman J, Jaffe E, Croce C . Involvement of bcl-2 gene in human follicular lymphoma. Science 1985; 228: 1440\u20131443.","journal-title":"Science"},{"key":"BF2403485_CR4","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1182\/blood.V99.1.282","volume":"99","author":"H Husson","year":"2002","unstructured":"Husson H, Carideo EG, Neuberg D, Schultze J, Munoz O, Marks PW et al. Gene expression profiling of follicular lymphoma and normal germinal center B cells using cDNA arrays. Blood 2002; 99: 282\u2013289.","journal-title":"Blood"},{"key":"BF2403485_CR5","first-page":"5010","volume":"44","author":"RC Braylan","year":"1984","unstructured":"Braylan RC, Benson NA, Nourse VA . Cellular DNA of human neoplastic B-cells measured by flow cytometry. Cancer Res 1984; 44: 5010\u20135016.","journal-title":"Cancer Res"},{"key":"BF2403485_CR6","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1182\/blood.V65.5.1090.1090","volume":"65","author":"J Srigley","year":"1985","unstructured":"Srigley J, Barlogie B, Butler JJ, Osborne B, Blick M, Johnston D et al. Heterogeneity of non-Hodgkin's lymphoma probed by nucleic acid cytometry. Blood 1985; 65: 1090\u20131096.","journal-title":"Blood"},{"key":"BF2403485_CR7","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1136\/jcp.36.2.167","volume":"36","author":"M Naiem","year":"1983","unstructured":"Naiem M, Gerdes J, Abdulaziz Z, Stein H, Mason DY . Production of a monoclonal antibody reactive with human dendritic reticulum cells and its use in the immunohistological analysis of lymphoid tissue. J Clin Pathol 1983; 36: 167\u2013175.","journal-title":"J Clin Pathol"},{"key":"BF2403485_CR8","doi-asserted-by":"crossref","first-page":"4832","DOI":"10.1182\/blood.V90.12.4832","volume":"90","author":"K Yamada","year":"1997","unstructured":"Yamada K, Yamakawa M, Imai Y, Tsukamoto M . Expression of cytokine receptors on follicular dendritic cells. Blood 1997; 90: 4832\u20134841.","journal-title":"Blood"},{"key":"BF2403485_CR9","doi-asserted-by":"crossref","first-page":"2550","DOI":"10.4049\/jimmunol.144.7.2550","volume":"144","author":"DT Umetsu","year":"1990","unstructured":"Umetsu DT, Esserman L, Donlon TA, DeKruyff RH, Levy R . Induction of proliferation of human follicular (B type) lymphoma cells by cognate interaction with CD4+ T cell clones. J Immunol 1990; 144: 2550\u20132557.","journal-title":"J Immunol"},{"key":"BF2403485_CR10","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/S0065-230X(00)79005-1","volume":"79","author":"P Ghia","year":"2000","unstructured":"Ghia P, Caligaris-Cappio F . The indispensable role of microenvironment in the natural history of low-grade B-cell neoplasms. Adv Cancer Res 2000; 79: 157\u2013173.","journal-title":"Adv Cancer Res"},{"key":"BF2403485_CR11","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1146\/annurev.biochem.67.1.753","volume":"67","author":"J Massague","year":"1998","unstructured":"Massague J . TGF-beta signal transduction. Annu Rev Biochem 1998; 67: 753\u2013791.","journal-title":"Annu Rev Biochem"},{"key":"BF2403485_CR12","doi-asserted-by":"publisher","first-page":"1297","DOI":"10.1016\/S1286-4579(99)00254-3","volume":"1","author":"DA Lebman","year":"1999","unstructured":"Lebman DA, Edmiston JS . The role of TGF-beta in growth, differentiation, and maturation of B lymphocytes. Microbes Infect 1999; 1: 1297\u20131304.","journal-title":"Microbes Infect"},{"key":"BF2403485_CR13","doi-asserted-by":"publisher","first-page":"F19","DOI":"10.1084\/jem.194.4.F19","volume":"194","author":"P Golstein","year":"2001","unstructured":"Golstein P, Wyllie AH . T cell death and transforming growth factor beta1. J Exp Med 2001; 194: F19\u2013F22.","journal-title":"J Exp Med"},{"key":"BF2403485_CR14","doi-asserted-by":"publisher","first-page":"2105","DOI":"10.1096\/fasebj.13.15.2105","volume":"13","author":"E Piek","year":"1999","unstructured":"Piek E, Heldin CH, Ten Dijke P . Specificity, diversity, and regulation in TGF-beta superfamily signaling. FASEB J 1999; 13: 2105\u20132124.","journal-title":"FASEB J"},{"key":"BF2403485_CR15","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1101\/gad.8.2.133","volume":"8","author":"DM Kingsley","year":"1994","unstructured":"Kingsley DM . The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev 1994; 8: 133\u2013146.","journal-title":"Genes Dev"},{"key":"BF2403485_CR16","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.1101\/gad.10.13.1580","volume":"10","author":"BL Hogan","year":"1996","unstructured":"Hogan BL . Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev 1996; 10: 1580\u20131594.","journal-title":"Genes Dev"},{"key":"BF2403485_CR17","doi-asserted-by":"publisher","first-page":"13637","DOI":"10.1074\/jbc.274.19.13637","volume":"274","author":"A Ishisaki","year":"1999","unstructured":"Ishisaki A, Yamato K, Hashimoto S, Nakao A, Tamaki K, Nonaka K et al. Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cells. J Biol Chem 1999; 274: 13637\u201313642.","journal-title":"J Biol Chem"},{"key":"BF2403485_CR18","doi-asserted-by":"publisher","first-page":"5496","DOI":"10.4049\/jimmunol.169.10.5496","volume":"169","author":"AL Hager-Theodorides","year":"2002","unstructured":"Hager-Theodorides AL, Outram SV, Shah DK, Sacedon R, Shrimpton RE, Vicente A et al. Bone morphogenetic protein 2\/4 signaling regulates early thymocyte differentiation. J Immunol 2002; 169: 5496\u20135504.","journal-title":"J Immunol"},{"key":"BF2403485_CR19","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1002\/1521-4141(200201)32:1<193::AID-IMMU193>3.0.CO;2-H","volume":"32","author":"S Franitza","year":"2002","unstructured":"Franitza S, Kollet O, Brill A, Vaday GG, Petit I, Lapidot T et al. TGF-beta1 enhances SDF-1alpha-induced chemotaxis and homing of naive T cells by up-regulating CXCR4 expression and downstream cytoskeletal effector molecules. Eur J Immunol 2002; 32: 193\u2013202.","journal-title":"Eur J Immunol"},{"key":"BF2403485_CR20","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1006\/cyto.2001.0922","volume":"15","author":"KS Tudor","year":"2001","unstructured":"Tudor KS, Hess KL, Cook-Mills JM . Cytokines modulate endothelial cell intracellular signal transduction required for VCAM-1-dependent lymphocyte transendothelial migration. Cytokine 2001; 15: 196\u2013211.","journal-title":"Cytokine"},{"key":"BF2403485_CR21","doi-asserted-by":"publisher","first-page":"36400","DOI":"10.1074\/jbc.M002131200","volume":"275","author":"CF Lai","year":"2000","unstructured":"Lai CF, Feng X, Nishimura R, Teitelbaum SL, Avioli LV, Ross FP et al. Transforming growth factor-beta up-regulates the beta 5 integrin subunit expression via Sp1 and Smad signaling. J Biol Chem 2000; 275: 36400\u201336406.","journal-title":"J Biol Chem"},{"key":"BF2403485_CR22","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1038\/nature02006","volume":"425","author":"R Derynck","year":"2003","unstructured":"Derynck R, Zhang Y . Smad-dependent and Smad-independent pathways in TGF-family signalling. Nature 2003; 425: 577\u2013584.","journal-title":"Nature"},{"key":"BF2403485_CR23","doi-asserted-by":"publisher","first-page":"3010.1","DOI":"10.1186\/gb-2001-2-8-reviews3010","volume":"2","author":"L Attisano","year":"2001","unstructured":"Attisano L, Tuen Lee-Hoeflich S . The smads. Genome Biol 2001; 2(8): 3010.1\u20133010.8.","journal-title":"Genome Biol"},{"key":"BF2403485_CR24","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/S0092-8674(00)81250-7","volume":"85","author":"PA Hoodless","year":"1996","unstructured":"Hoodless PA, Haerry T, Abdollah S, Stapleton M, O'Connor MB, Attisano L et al. MADR1, a MAD-related protein that functions in BMP2 signaling pathways. Cell 1996; 85: 489\u2013500.","journal-title":"Cell"},{"key":"BF2403485_CR25","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1038\/381620a0","volume":"381","author":"F Liu","year":"1996","unstructured":"Liu F, Hata A, Baker JC, Doody J, Carcamo J, Harland RM et al. A human Mad protein acting as a BMP-regulated transcriptional activator. Nature 1996; 381: 620\u2013623.","journal-title":"Nature"},{"key":"BF2403485_CR26","doi-asserted-by":"publisher","first-page":"2896","DOI":"10.1074\/jbc.272.5.2896","volume":"272","author":"A Nakao","year":"1997","unstructured":"Nakao A, Roijer E, Imamura T, Souchelnytskyi S, Stenman G, Heldin CH et al. Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway. J Biol Chem 1997; 272: 2896\u20132900.","journal-title":"J Biol Chem"},{"key":"BF2403485_CR27","doi-asserted-by":"publisher","first-page":"1646","DOI":"10.1126\/science.1071809","volume":"296","author":"L Attisano","year":"2002","unstructured":"Attisano L, Wrana JL . Signal transduction by the TGF-beta superfamily. Science 2002; 296: 1646\u20131647.","journal-title":"Science"},{"key":"BF2403485_CR28","doi-asserted-by":"publisher","first-page":"2033","DOI":"10.1038\/sj.onc.1202521","volume":"18","author":"J Yue","year":"1999","unstructured":"Yue J, Frey RS, Mulder KM . Cross-talk between the Smad1 and Ras\/MEK signaling pathways for TGFbeta. Oncogene 1999; 18: 2033\u20132037.","journal-title":"Oncogene"},{"key":"BF2403485_CR29","doi-asserted-by":"publisher","first-page":"1743","DOI":"10.1093\/emboj\/21.7.1743","volume":"21","author":"MJ Goumans","year":"2002","unstructured":"Goumans MJ, Valdimarsdottir G, Itoh S, Rosendahl A, Sideras P, ten Dijke P . Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors. EMBO J 2002; 21: 1743\u20131753.","journal-title":"EMBO J"},{"key":"BF2403485_CR30","first-page":"7791","volume":"63","author":"S Matsuyama","year":"2003","unstructured":"Matsuyama S, Iwadate M, Kondo M, Saitoh M, Hanyu A, Shimizu K et al. SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells. Cancer Res 2003; 63: 7791\u20137798.","journal-title":"Cancer Res"},{"key":"BF2403485_CR31","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1002\/jcp.10170","volume":"193","author":"T Ota","year":"2002","unstructured":"Ota T, Fujii M, Sugizaki T, Ishii M, Miyazawa K, Aburatani H et al. Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-beta in human umbilical vein endothelial cells. J Cell Physiol 2002; 193: 299\u2013318.","journal-title":"J Cell Physiol"},{"key":"BF2403485_CR32","doi-asserted-by":"publisher","first-page":"2626","DOI":"10.1073\/pnas.97.6.2626","volume":"97","author":"SP Oh","year":"2000","unstructured":"Oh SP, Seki T, Goss KA, Imamura T, Yi Y, Donahoe PK et al. Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis. Proc Natl Acad Sci USA 2000; 97: 2626\u20132631.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF2403485_CR33","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1006\/cimm.2000.1688","volume":"203","author":"H Husson","year":"2000","unstructured":"Husson H, Lugli SM, Ghia P, Cardoso A, Roth A, Brohmi K et al. Functional effects of TNF and lymphotoxin alpha1beta2 on FDC-like cells. Cell Immunol 2000; 203: 134\u2013143.","journal-title":"Cell Immunol"},{"key":"BF2403485_CR34","first-page":"3071","volume":"61","author":"T Hideshima","year":"2001","unstructured":"Hideshima T, Richardson P, Chauhan D, Palombella VJ, Elliott PJ, Adams J et al. The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res 2001; 61: 3071\u20133076.","journal-title":"Cancer Res"},{"key":"BF2403485_CR35","first-page":"221","volume":"5","author":"HC Kluin-Nelemans","year":"1991","unstructured":"Kluin-Nelemans HC, Limpens J, Meerabux J, Beverstock GC, Jansen JH, de Jong D et al. A new non-Hodgkin's B-cell line (DoHH2) with a chromosomal translocation t(14;18)(q32;q21). Leukemia 1991; 5: 221\u2013224.","journal-title":"Leukemia"},{"key":"BF2403485_CR36","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1038\/sj.leu.2402372","volume":"16","author":"T Denyssevych","year":"2002","unstructured":"Denyssevych T, Lestou VS, Knesevich S, Robichaud M, Salski C, Tan R et al. Establishment and comprehensive analysis of a new human transformed follicular lymphoma B cell line, Tat-1. Leukemia 2002; 16: 276\u2013283.","journal-title":"Leukemia"},{"key":"BF2403485_CR37","first-page":"1748","volume":"39","author":"AL Epstein","year":"1979","unstructured":"Epstein AL, Kaplan HS . Feeder layer and nutritional requirements for the establishment and cloning of human malignant lymphoma cell lines. Cancer Res 1979; 39: 1748\u20131759.","journal-title":"Cancer Res"},{"key":"BF2403485_CR38","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1074\/jbc.272.1.228","volume":"272","author":"A Astier","year":"1997","unstructured":"Astier A, Avraham H, Manie SN, Groopman J, Canty T, Avraham S et al. The related adhesion focal tyrosine kinase is tyrosine-phosphorylated after beta1-integrin stimulation in B cells and binds to p130cas. J Biol Chem 1997; 272: 228\u2013232.","journal-title":"J Biol Chem"},{"key":"BF2403485_CR39","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1677\/joe.0.1720187","volume":"172","author":"F Pouliot","year":"2002","unstructured":"Pouliot F, Labrie C . Role of Smad1 and Smad4 proteins in the induction of p21WAF1, Cip1 during bone morphogenetic protein-induced growth arrest in human breast cancer cells. J Endocrinol 2002; 172: 187\u2013198.","journal-title":"J Endocrinol"},{"key":"BF2403485_CR40","first-page":"16","volume":"16","author":"Z Xiao","year":"2001","unstructured":"Xiao Z, Watson N, Rodriguez C, Lodish HF . Nucleocytoplasmic shuttling of Smad1 conferred by its nuclear localization and nuclear export signals. J Biol Chem 2001; 16: 16.","journal-title":"J Biol Chem"},{"key":"BF2403485_CR41","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1091\/mbc.11.2.555","volume":"11","author":"K Kusanagi","year":"2000","unstructured":"Kusanagi K, Inoue H, Ishidou Y, Mishima HK, Kawabata M, Miyazono K . Characterization of a bone morphogenetic protein-responsive Smad-binding element. Mol Cell Biol 2000; 11: 555\u2013565.","journal-title":"Mol Cell Biol"},{"key":"BF2403485_CR42","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1038\/39348","volume":"389","author":"M Kretzschmar","year":"1997","unstructured":"Kretzschmar M, Doody J, Massague J . Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1. Nature 1997; 389: 618\u2013622.","journal-title":"Nature"},{"key":"BF2403485_CR43","doi-asserted-by":"crossref","first-page":"4467","DOI":"10.1242\/dev.124.22.4467","volume":"124","author":"AF Candia","year":"1997","unstructured":"Candia AF, Watabe T, Hawley SH, Onichtchouk D, Zhang Y, Derynck R et al. Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin\/BVg1 and BMP-2\/4 signaling mediated by Smads. Development 1997; 124: 4467\u20134480.","journal-title":"Development"},{"key":"BF2403485_CR44","doi-asserted-by":"publisher","first-page":"6954","DOI":"10.1046\/j.1432-1327.2000.01828.x","volume":"267","author":"S Itoh","year":"2000","unstructured":"Itoh S, Itoh F, Goumans MJ, Ten Dijke P . Signaling of transforming growth factor-beta family members through Smad proteins. Eur J Biochem 2000; 267: 6954\u20136967.","journal-title":"Eur J Biochem"},{"key":"BF2403485_CR45","doi-asserted-by":"publisher","first-page":"9984","DOI":"10.1074\/jbc.274.15.9984","volume":"274","author":"A Lux","year":"1999","unstructured":"Lux A, Attisano L, Marchuk DA . Assignment of transforming growth factor beta1 and beta3 and a third new ligand to the type I receptor ALK-1. J Biol Chem 1999; 274: 9984\u20139992.","journal-title":"J Biol Chem"},{"key":"BF2403485_CR46","doi-asserted-by":"publisher","first-page":"3672","DOI":"10.1074\/jbc.274.6.3672","volume":"274","author":"YG Chen","year":"1999","unstructured":"Chen YG, Massague J . Smad1 recognition and activation by the ALK1 group of transforming growth factor-beta family receptors. J Biol Chem 1999; 274: 3672\u20133677.","journal-title":"J Biol Chem"},{"key":"BF2403485_CR47","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1111\/j.1349-7006.2003.tb01518.x","volume":"94","author":"Y Maesako","year":"2003","unstructured":"Maesako Y, Uchiyama T, Ohno H . Comparison of gene expression profiles of lymphoma cell lines from transformed follicular lymphoma, Burkitt's lymphoma and de novo diffuse large B-cell lymphoma. Cancer Sci 2003; 94: 774\u2013781.","journal-title":"Cancer Sci"},{"key":"BF2403485_CR48","doi-asserted-by":"crossref","first-page":"117","DOI":"10.4049\/jimmunol.159.1.117","volume":"159","author":"J Tang","year":"1997","unstructured":"Tang J, Nuccie BL, Ritterman I, Liesveld JL, Abboud CN, Ryan DH . TGF-beta down-regulates stromal IL-7 secretion and inhibits proliferation of human B cell precursors. J Immunol 1997; 159: 117\u2013125.","journal-title":"J Immunol"},{"key":"BF2403485_CR49","doi-asserted-by":"publisher","first-page":"2725","DOI":"10.1002\/eji.1830221037","volume":"22","author":"MJ Holder","year":"1992","unstructured":"Holder MJ, Knox K, Gordon J . Factors modifying survival pathways of germinal center B cells. Glucocorticoids and transforming growth factor-beta, but not cyclosporin A or anti-CD19, block surface immunoglobulin-mediated rescue from apoptosis. Eur J Immunol 1992; 22: 2725\u20132728.","journal-title":"Eur J Immunol"},{"key":"BF2403485_CR50","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1006\/bcmd.1999.0259","volume":"25","author":"K Detmer","year":"1999","unstructured":"Detmer K, Steele TA, Shoop MA, Dannawi H . Lineage-restricted expression of bone morphogenetic protein genes in human hematopoietic cell lines. Blood Cells Mol Dis 1999; 25: 310\u2013323.","journal-title":"Blood Cells Mol Dis"},{"key":"BF2403485_CR51","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1093\/nar\/23.4.628","volume":"23","author":"Y Soneoka","year":"1995","unstructured":"Soneoka Y, Cannon PM, Ramsdale EE, Griffiths JC, Romano G, Kingsman SM et al. A transient three-plasmid expression system for the production of high titer retroviral vectors. Nucleic Acids Res 1995; 23: 628\u2013633.","journal-title":"Nucleic Acids Res"}],"container-title":["Leukemia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/2403485.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/2403485","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/2403485.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,29]],"date-time":"2023-04-29T13:21:49Z","timestamp":1682774509000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/2403485"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,10,7]]},"references-count":51,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2004,12,1]]}},"alternative-id":["BF2403485"],"URL":"https:\/\/doi.org\/10.1038\/sj.leu.2403485","relation":{},"ISSN":["0887-6924","1476-5551"],"issn-type":[{"value":"0887-6924","type":"print"},{"value":"1476-5551","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,10,7]]},"assertion":[{"value":"29 December 2003","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 July 2004","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 October 2004","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}