{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T09:56:50Z","timestamp":1791194210715,"version":"4.1.0"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2005,9,15]],"date-time":"2005-09-15T00:00:00Z","timestamp":1126742400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2005,9,15]],"date-time":"2005-09-15T00:00:00Z","timestamp":1126742400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Leukemia"],"published-print":{"date-parts":[[2005,11,1]]},"DOI":"10.1038\/sj.leu.2403945","type":"journal-article","created":{"date-parts":[[2005,9,15]],"date-time":"2005-09-15T14:05:29Z","timestamp":1126793129000},"page":"1912-1918","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":113,"title":["Risk factors of myelodysplastic syndromes: a case\u2013control study"],"prefix":"10.1038","volume":"19","author":[{"given":"S S","family":"Strom","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S K","family":"Gruschkus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S A","family":"Pierce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E H","family":"Estey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2005,9,15]]},"reference":[{"key":"BF2403945_CR1","doi-asserted-by":"crossref","unstructured":"Greenberg PL, Young NS, Gattermann N . Myelodysplastic syndromes. Hematology (Am Soc Hematol Educ Program) 2002, 136\u2013161.","DOI":"10.1182\/asheducation-2002.1.136"},{"key":"BF2403945_CR2","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1111\/j.1365-2141.1982.tb08475.x","volume":"51","author":"JM Bennett","year":"1982","unstructured":"Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DA, Gralnick HR et al. Proposals for the classification of the myelodysplastic syndromes. Br J Haematol 1982; 51: 189\u2013199.","journal-title":"Br J Haematol"},{"key":"BF2403945_CR3","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/0002-9343(72)90065-4","volume":"52","author":"M Aksoy","year":"1972","unstructured":"Aksoy M, Dincol K, Erdem S, Dincol G . Acute leukemia due to chronic exposure to benzene. Am J Med 1972; 52: 160\u2013166.","journal-title":"Am J Med"},{"issue":"Suppl 6","key":"BF2403945_CR4","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1289\/ehp.961041349","volume":"104","author":"RB Hayes","year":"1996","unstructured":"Hayes RB, Yin SN, Dosemeci M, Li GL, Wacholder S, Chow WH et al. Mortality among benzene-exposed workers in China. Environ Health Perspect 1996; 104 (Suppl 6): 1349\u20131352.","journal-title":"Environ Health Perspect"},{"issue":"Suppl 6","key":"BF2403945_CR5","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1289\/ehp.961041339","volume":"104","author":"SN Yin","year":"1996","unstructured":"Yin SN, Hayes RB, Linet MS, Li GL, Dosemeci M, Travis LB et al. An expanded cohort study of cancer among benzene-exposed workers in China. Benzene Study Group. Environ Health Perspect 1996; 104 (Suppl 6): 1339\u20131341.","journal-title":"Environ Health Perspect"},{"key":"BF2403945_CR6","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1136\/oem.55.8.517","volume":"55","author":"RI Nilsson","year":"1998","unstructured":"Nilsson RI, Nordlinder R, Horte LG, Jarvholm B . Leukaemia, lymphoma, and multiple myeloma in seamen on tankers. Occup Environ Med 1998; 55: 517\u2013521.","journal-title":"Occup Environ Med"},{"key":"BF2403945_CR7","first-page":"511","volume":"48","author":"D Christie","year":"1991","unstructured":"Christie D, Robinson K, Gordon I, Bisby J . A prospective study in the Australian petroleum industry. II. Incidence of cancer. Br J Ind Med 1991; 48: 511\u2013514.","journal-title":"Br J Ind Med"},{"key":"BF2403945_CR8","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/0145-2126(94)00141-V","volume":"19","author":"RR West","year":"1995","unstructured":"West RR, Stafford DA, Farrow A, Jacobs A . Occupational and environmental exposures and myelodysplasia: a case\u2013control study. Leuk Res 1995; 19: 127\u2013139.","journal-title":"Leuk Res"},{"key":"BF2403945_CR9","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1016\/0145-2126(96)00042-2","volume":"20","author":"M Ido","year":"1996","unstructured":"Ido M, Nagata C, Kawakami N, Shimizu H, Yoshida Y, Nomura T et al. A case\u2013control study of myelodysplastic syndromes among Japanese men and women. Leuk Res 1996; 20: 727\u2013731.","journal-title":"Leuk Res"},{"key":"BF2403945_CR10","first-page":"693","volume":"9","author":"C Nisse","year":"1995","unstructured":"Nisse C, Lorthois C, Dorp V, Eloy E, Haguenoer J, Fenaux P . Exposure to occupational and environmental factors in myelodysplastic syndromes. Preliminary results of a case\u2013control study. Leukemia 1995; 9: 693\u2013699.","journal-title":"Leukemia"},{"key":"BF2403945_CR11","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1046\/j.1365-2141.1997.942910.x","volume":"97","author":"P Pasqualetti","year":"1997","unstructured":"Pasqualetti P, Festuccia V, Acitelli P, Collacciana A, Giusti A, Casale R . Tobacco smoking and risk of haematological malignancies in adults: a case\u2013control study. Br J Haematol 1997; 97: 659\u2013662.","journal-title":"Br J Haematol"},{"issue":"Suppl 6","key":"BF2403945_CR12","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1289\/ehp.93101s663","volume":"101","author":"O Wong","year":"1993","unstructured":"Wong O, Harris F, Smith TJ . Health effects of gasoline exposure. II. Mortality patterns of distribution workers in the United States. Environ Health Perspect 1993; 101 (Suppl 6): 63\u201376.","journal-title":"Environ Health Perspect"},{"key":"BF2403945_CR13","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1289\/ehp.98106115","volume":"106","author":"L Caprino","year":"1998","unstructured":"Caprino L, Togna GI . Potential health effects of gasoline and its constituents: a review of current literature (1990\u20131997) on toxicological data. Environ Health Perspect 1998; 106: 115\u2013125.","journal-title":"Environ Health Perspect"},{"key":"BF2403945_CR14","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/S0145-2126(98)00135-0","volume":"23","author":"C Nagata","year":"1999","unstructured":"Nagata C, Shimizu H, Hirashima K, Kakishita E, Fujimura K, Niho Y et al. Hair dye use and occupational exposure to organic solvents as risk factors for myelodysplastic syndrome. Leuk Res 1999; 23: 57\u201362.","journal-title":"Leuk Res"},{"key":"BF2403945_CR15","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1016\/S0749-3797(18)31172-3","volume":"4","author":"MR Spitz","year":"1988","unstructured":"Spitz MR, Fueger JJ, Newell GR . The development of a comprehensive, institution-based patient risk evaluation program: II. Validity and reliability of questionnaire data. Am J Prev Med 1988; 4: 188\u2013193.","journal-title":"Am J Prev Med"},{"key":"BF2403945_CR16","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1097\/00001648-199401000-00019","volume":"5","author":"M Dosemeci","year":"1994","unstructured":"Dosemeci M, Cocco P, Gomez M, Stewart PA, Heineman EF . Effects of three features of a job-exposure matrix on risk estimates. Epidemiology 1994; 5: 124\u2013127.","journal-title":"Epidemiology"},{"key":"BF2403945_CR17","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1097\/00001648-200005000-00010","volume":"11","author":"J Bjork","year":"2000","unstructured":"Bjork J, Albin M, Mauritzson N, Stromberg U, Johansson B, Hagmar L . Smoking and myelodysplastic syndromes. Epidemiology 2000; 11: 285\u2013291.","journal-title":"Epidemiology"},{"key":"BF2403945_CR18","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/0165-4608(93)90010-J","volume":"68","author":"G Ciccone","year":"1993","unstructured":"Ciccone G, Mirabelli D, Levis A, Gavarotti P, Rege-Cambrin G, Davico L et al. Myeloid leukemias and myelodysplastic syndromes: chemical exposure, histologic subtype and cytogenetics in a case-control study. Cancer Genet Cytogenet 1993; 68: 135\u2013139.","journal-title":"Cancer Genet Cytogenet"},{"key":"BF2403945_CR19","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1002\/ijc.2910590206","volume":"59","author":"CN Ong","year":"1994","unstructured":"Ong CN, Lee BL, Shi CY, Ong HY, Lee HP . Elevated levels of benzene-related compounds in the urine of cigarette smokers. Int J Cancer 1994; 59: 177\u2013180.","journal-title":"Int J Cancer"},{"key":"BF2403945_CR20","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1002\/ajh.2830380216","volume":"38","author":"P Pasqualetti","year":"1991","unstructured":"Pasqualetti P, Casale R, Colantonio D, Collacciani A . Occupational risk for hematological malignancies. Am J Hematol 1991; 38: 147\u2013149.","journal-title":"Am J Hematol"},{"key":"BF2403945_CR21","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1023\/A:1019573319803","volume":"13","author":"M Dalamage","year":"2002","unstructured":"Dalamage M, Petridou E, Cook F, Trichopoulos D . Risk factors for myelodysplastic syndromes: a case\u2013control study in Greece. Cancer Causes Control 2002; 13: 603\u2013608.","journal-title":"Cancer Causes Control"},{"key":"BF2403945_CR22","doi-asserted-by":"publisher","first-page":"1476","DOI":"10.1038\/sj.bjc.6690547","volume":"80","author":"BC Chiu","year":"1999","unstructured":"Chiu BC, Cerhan JR, Gapstur SM, Sellers TA, Zheng W, Lutz CT et al. Alcohol consumption and non-Hodgkin lymphoma in a cohort of older women. Br J Cancer 1999; 80: 1476\u20131482.","journal-title":"Br J Cancer"},{"key":"BF2403945_CR23","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/S0145-2126(97)00194-X","volume":"22","author":"E De Stefani","year":"1998","unstructured":"De Stefani E, Fierro L, Barrios E, Ronco A . Tobacco, alcohol, diet and risk of non-Hodgkin's lymphoma: a case\u2013control study in Uruguay. Leuk Res 1998; 22: 445\u2013452.","journal-title":"Leuk Res"},{"key":"BF2403945_CR24","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1093\/aje\/kwf058","volume":"156","author":"NC Briggs","year":"2002","unstructured":"Briggs NC, Levine RS, Bobo LD, Haliburton WP, Brann EA, Hennekens CH . Wine drinking and risk of non-Hodgkin's lymphoma among men in the United States: a population-based case\u2013control study. Am J Epidemiol 2002; 156: 454\u2013462.","journal-title":"Am J Epidemiol"},{"key":"BF2403945_CR25","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1023\/A:1025626208861","volume":"14","author":"LM Morton","year":"2003","unstructured":"Morton LM, Holford TR, Leaderer B, Zhang Y, Zahm SH, Boyle P et al. Alcohol use and risk of non-Hodgkin's lymphoma among Connecticut women (United States). Cancer Causes Control 2003; 14: 687\u2013694.","journal-title":"Cancer Causes Control"},{"key":"BF2403945_CR26","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1097\/00008469-200310000-00011","volume":"12","author":"F Bianchini","year":"2003","unstructured":"Bianchini F, Vainio H . Wine and resveratrol: mechanisms of cancer prevention? Eur J Cancer Prev 2003; 12: 417\u2013425.","journal-title":"Eur J Cancer Prev"},{"key":"BF2403945_CR27","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1080\/10428190290021669","volume":"43","author":"MF Tsan","year":"2002","unstructured":"Tsan MF, White JE, Maheshwari JG, Chikkappa G . Anti-leukemia effect of resveratrol. Leuk Lymphoma 2002; 43: 983\u2013987.","journal-title":"Leuk Lymphoma"},{"key":"BF2403945_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0304-3835(99)00039-7","volume":"140","author":"YJ Surh","year":"1999","unstructured":"Surh YJ, Hurh YJ, Kang E, Kong G, Lee SJ . Resveratrol, an antioxidant present in red wine, induces apoptosis in human promyelocytic leukemia (HL-60) cells. Cancer Lett 1999; 140: 1\u201310.","journal-title":"Cancer Lett"},{"key":"BF2403945_CR29","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1126\/science.275.5297.218","volume":"275","author":"M Jang","year":"1997","unstructured":"Jang M, Cai L, Udeani O, Slowing KV, Thomas CF, Beecher CW et al. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 1997; 275: 218\u2013220.","journal-title":"Science"},{"key":"BF2403945_CR30","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1182\/blood.V92.3.996","volume":"92","author":"MV Clement","year":"1998","unstructured":"Clement MV, Hirpara JL, Vhadhury SH, Pervaiz S . Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells. Blood 1998; 92: 996\u20131002.","journal-title":"Blood"},{"key":"BF2403945_CR31","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1046\/j.1365-2141.1998.00963.x","volume":"103","author":"GM Rigolin","year":"1998","unstructured":"Rigolin GM, Cuneo A, Roberti MG, Bardi A, Bigoni R, Piva N et al. Exposure to myelotoxic agents and myelodysplasia: case\u2013control study and correlation with clinicobiological findings. Br J Haematol 1998; 103: 189\u2013197.","journal-title":"Br J Haematol"},{"key":"BF2403945_CR32","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1046\/j.1365-2141.2001.02645.x","volume":"12","author":"C Nisse","year":"2001","unstructured":"Nisse C, Haguenoer JM, Granbastuen B, Preudhomme C, Fontaine B, Brillet JM et al. Occupational and environmental risk factors of the myelodysplastic syndromes in the North of France. Br J Haematol 2001; 12: 927\u2013935.","journal-title":"Br J Haematol"},{"key":"BF2403945_CR33","first-page":"6876","volume":"50","author":"H Goldberg","year":"1990","unstructured":"Goldberg H, Lusk E, Moore J, Nowell PC, Besa PC . Survey of exposure to genotoxic agents in primary myelodysplastic syndrome \u2013 correlation with chromosome patterns and data in patients without haematological disease. Cancer Res 1990; 50: 6876\u20136881.","journal-title":"Cancer Res"},{"key":"BF2403945_CR34","doi-asserted-by":"publisher","first-page":"378","DOI":"10.5271\/sjweh.744","volume":"29","author":"M Albin","year":"2003","unstructured":"Albin M, Bjork J, Welinder H, Tinnerberg H, Mauritzson N, Billstrom R et al. Cytogenetic and morphologic subgroups of myelodysplastic syndromes in relation to occupational and hobby exposures. Scand J Work Environ Health 2003; 29: 378\u2013387.","journal-title":"Scand J Work Environ Health"},{"key":"BF2403945_CR35","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1007\/BF02994001","volume":"73","author":"C Aul","year":"2001","unstructured":"Aul C, Giagounidis A, Germing U . Epidemiological features of myelodysplastic syndromes: results from regional cancer surveys and hospital-based statistics. Int J Hematol 2001; 73: 405\u2013410.","journal-title":"Int J Hematol"},{"key":"BF2403945_CR36","volume-title":"The Myelodysplastic Syndromes Pathobiology and Clinical Management","author":"J Phellan","year":"2002","unstructured":"Phellan J, Kouides P, Bennet J . Myelodysplatic syndromes: historical aspects and classification. In: Bennet J (ed). The Myelodysplastic Syndromes Pathobiology and Clinical Management. New York: Marcel Dekker Inc., 2002."},{"key":"BF2403945_CR37","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1136\/oem.59.9.575","volume":"59","author":"K Teschke","year":"2002","unstructured":"Teschke K, Olshan AF, Daniels JL, De Roos AJ, Parks CG, Schulz M et al. Occupational exposure assessment in case\u2013control studies: opportunities for improvement. Occup Environ Med 2002; 59: 575\u2013594.","journal-title":"Occup Environ Med"}],"container-title":["Leukemia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/2403945.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/2403945","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/2403945.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T01:45:07Z","timestamp":1648777507000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/2403945"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,9,15]]},"references-count":37,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2005,11,1]]}},"alternative-id":["BF2403945"],"URL":"https:\/\/doi.org\/10.1038\/sj.leu.2403945","relation":{},"ISSN":["0887-6924","1476-5551"],"issn-type":[{"value":"0887-6924","type":"print"},{"value":"1476-5551","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,9,15]]},"assertion":[{"value":"21 April 2005","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 August 2005","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 September 2005","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}