{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T11:48:05Z","timestamp":1775303285585,"version":"3.50.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2000,12,14]],"date-time":"2000-12-14T00:00:00Z","timestamp":976752000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2000,12,14]],"date-time":"2000-12-14T00:00:00Z","timestamp":976752000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Psychiatry"],"published-print":{"date-parts":[[2001,1,1]]},"DOI":"10.1038\/sj.mp.4000790","type":"journal-article","created":{"date-parts":[[2002,9,4]],"date-time":"2002-09-04T18:46:11Z","timestamp":1031165171000},"page":"74-78","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Lack of evidence to support the association of the human prion gene with schizophrenia"],"prefix":"10.1038","volume":"6","author":[{"given":"M-T","family":"Tsai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y-C","family":"Su","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y-H","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C-H","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2000,12,14]]},"reference":[{"key":"BF4000790_CR1","doi-asserted-by":"publisher","first-page":"1699","DOI":"10.1093\/hmg\/6.10.1699","volume":"6","author":"J Collinge","year":"1997","unstructured":"Collinge J . Human prion disease and bovine spongiform encephalopathy (BSE) Hum Mol Genet 1997 6: 1699\u20131705","journal-title":"Hum Mol Genet"},{"key":"BF4000790_CR2","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/0014-5793(96)00610-2","volume":"389","author":"C Weissmann","year":"1996","unstructured":"Weissmann C . Molecular biology of transmissible spongiform encephalopathies FEBS Lett 1996 389: 3\u201311","journal-title":"FEBS Lett"},{"key":"BF4000790_CR3","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/BF02780658","volume":"8","author":"LG Goldfarb","year":"1994","unstructured":"Goldfarb LG, Brown P, Cervenakova L, Gajdusek DC . Molecular genetic studies of Creutzfeldt\u2013Jakob disease Mol Neurobiol 1994 8: 89\u201397","journal-title":"Mol Neurobiol"},{"key":"BF4000790_CR4","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1016\/S0140-6736(96)91407-5","volume":"347","author":"J Collinge","year":"1996","unstructured":"Collinge J, Rossor M . A new variant of prion disease Lancet 1996 347: 916\u2013917","journal-title":"Lancet"},{"key":"BF4000790_CR5","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1136\/jnnp.47.2.134","volume":"47","author":"RG Will","year":"1984","unstructured":"Will RG, Matthews WB . A retrospective study of Creutzfeldt\u2013Jakob disease in England and Wales 1970\u20131979. I: Clinical features J Neurol Neurosurg Psychiatry 1984 47: 134\u2013140","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"BF4000790_CR6","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1002\/ana.410060510","volume":"6","author":"P Brown","year":"1979","unstructured":"Brown P, Cathala F, Sadowsky D, Gajdusek DC . Creutzfeldt\u2013Jakob disease in France III. Clinical characteristics of 124 consecutive verified cases during the decade 1968\u20131977 Ann Neurol 1979 6: 430\u2013437","journal-title":"Ann Neurol"},{"key":"BF4000790_CR7","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1016\/S0140-6736(96)91412-9","volume":"347","author":"RG Will","year":"1996","unstructured":"Will RG, Ironside JW, Zeidler M, Cousens SN, Estibeiro K, Alperovitch A et al. A new variant of Creutzfeldt\u2013Jakob disease in the UK Lancet 1996 347: 921\u2013925","journal-title":"Lancet"},{"key":"BF4000790_CR8","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1016\/S0140-6736(97)03148-6","volume":"350","author":"M Zeidler","year":"1997","unstructured":"Zeidler M, Johnstone EC, Bamber RWK, Dickens CM, Fisher CJ, Francis AF et al. New variant Creutzfeldt\u2013Jakob disease: psychiatric features Lancet 1997 350: 908\u2013910","journal-title":"Lancet"},{"key":"BF4000790_CR9","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1192\/bjp.170.4.298","volume":"170","author":"PJ Harrison","year":"1997","unstructured":"Harrison PJ . BSE and human prion disease Br J Psychiatry 1997 170: 298\u2013300","journal-title":"Br J Psychiatry"},{"key":"BF4000790_CR10","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1038\/36757","volume":"390","author":"HB Samaia","year":"1997","unstructured":"Samaia HB, de Jesus Mari J, Vallada HP, Moura RP, Simpson AJG, Brentani RR . A prion-linked psychiatric disorder Nature 1997 390: 241","journal-title":"Nature"},{"key":"BF4000790_CR11","doi-asserted-by":"publisher","first-page":"7358","DOI":"10.1073\/pnas.83.19.7358","volume":"83","author":"RS Sparkes","year":"1986","unstructured":"Sparkes RS, Simon M, Cohn VH, Fournier REK, Lem J, Klisak I et al. Assignment of the human and mouse prion protein genes to homologous chromosomes Proc Natl Acad Sci USA 1986 83: 7358\u20137362","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF4000790_CR12","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1101\/gr.8.10.1022","volume":"8","author":"IY Lee","year":"1998","unstructured":"Lee IY, Westaway D, Smit AFA, Wang K, Seto J, Chen L et al. Complete genomic sequence and analysis of the prion protein gene region from three mammalian species Genome Res 1998 8: 1022\u20131037","journal-title":"Genome Res"},{"key":"BF4000790_CR13","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1038\/352340a0","volume":"352","author":"MS Palmer","year":"1991","unstructured":"Palmer MS, Dryden AJ, Hughes JT, Collinge J . Homozygous prion protein genotype predisposes to sporadic Creutzfeldt\u2013Jakob disease Nature 1991 352: 340\u2013341","journal-title":"Nature"},{"key":"BF4000790_CR14","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/0169-328X(95)00034-P","volume":"30","author":"H Furukawa","year":"1995","unstructured":"Furukawa H, Kitamoto T, Tanaka Y, Tateishi J . New variant prion protein in a Japanese family with Gerstmann\u2013Strauessler syndrome Mol Brain Res 1995 30: 385\u2013388","journal-title":"Mol Brain Res"},{"key":"BF4000790_CR15","volume-title":"Arlequin, Version 1.1: a software for population genetic data analysis","author":"S Schneider","year":"1997","unstructured":"Schneider S, Kueffer J-M, Roessli D, Excoffer I . Arlequin, Version 1.1: a software for population genetic data analysis Genetics and Biometry Laboratory, University of Geneva 1997"},{"key":"BF4000790_CR16","volume-title":"Analysis of Human Genetic Linkage, rev edn","author":"J Ott","year":"1991","unstructured":"Ott J . Analysis of Human Genetic Linkage, rev edn Johns Hopkins University Press: Baltimore 1991"},{"key":"BF4000790_CR17","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1192\/bjp.151.2.260","volume":"151","author":"MS Keshavan","year":"1987","unstructured":"Keshavan MS, Lishman WA, Haghes JT . Psychiatric presentation of Creutzfeldt\u2013Jakob disease. A case report Br J Psychiatry 1987 151: 260\u2013263","journal-title":"Br J Psychiatry"},{"key":"BF4000790_CR18","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/0010-440X(93)90034-2","volume":"34","author":"JM Azorin","year":"1993","unstructured":"Azorin JM, Donnet A, Dassa D et al. Creutzfeldt\u2013Jakob disease misdiagnosed as depressive pseudodementia Compr Psychiatry 1993 34: 42\u201344","journal-title":"Compr Psychiatry"},{"key":"BF4000790_CR19","first-page":"445","volume":"40","author":"EM Stevens","year":"1979","unstructured":"Stevens EM, Lament R . Psychiatric presentation of Creutzfeldt\u2013Jakob disease J Clin Psychiatry 1979 40: 445\u2013446","journal-title":"J Clin Psychiatry"},{"key":"BF4000790_CR20","first-page":"263","volume":"13","author":"CF Yen","year":"1997","unstructured":"Yen CF, Lin RT, Liu CK, Lee PW, Hen CC, Chang YP . The psychiatric manifestation of Creutzfeldt\u2013Jakob disease Kao Hsiung I Hsueh Ko Hsueh Tsa Chih 1997 13: 263\u2013267","journal-title":"Kao Hsiung I Hsueh Ko Hsueh Tsa Chih"},{"key":"BF4000790_CR21","first-page":"282","volume":"1","author":"RE Snow","year":"1996","unstructured":"Snow RE, Arnold SE . Psychosis in neurodegenerative disease Semin Clin Neuropsychiatry 1996 1: 282\u2013293","journal-title":"Semin Clin Neuropsychiatry"},{"key":"BF4000790_CR22","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1002\/humu.1380020303","volume":"2","author":"M Palmer","year":"1993","unstructured":"Palmer M, Collinge J . Mutations and polymorphisms in the prion protein gene Hum Mut 1993 2: 168\u2013173","journal-title":"Hum Mut"},{"key":"BF4000790_CR23","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/S0092-8674(00)81163-0","volume":"93","author":"SR Prusiner","year":"1998","unstructured":"Prusiner SR, Scott MR, DeArmond SJ, Cohen FE . Prion protein biology Cell 1998 93: 337\u2013348","journal-title":"Cell"},{"key":"BF4000790_CR24","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1136\/jnnp.66.1.90","volume":"66","author":"SE Arnold","year":"1999","unstructured":"Arnold SE, Trojanowski JQ, Parchi P . Protease resistant prion proteins are not present in sporadic \u2018poor outcome\u2019 schizophrenia J Neurol Neurosurg Psychiatry 1999 66: 90\u201392","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"BF4000790_CR25","doi-asserted-by":"publisher","first-page":"1441","DOI":"10.1016\/0140-6736(91)93128-V","volume":"337","author":"J Collinge","year":"1991","unstructured":"Collinge J, Palmer MS, Dryden AJ . Genetics predisposition to iatrogenic Creutzfeldt\u2013Jakob disease Lancet 1991 337: 1441\u20131442","journal-title":"Lancet"},{"key":"BF4000790_CR26","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1126\/science.1439789","volume":"258","author":"LG Goldfarb","year":"1992","unstructured":"Goldfarb LG, Petersen RB, Tabaton M, Brown P, LeBlanc AC, Montagna P et al. Fatal familial insomnia and familial CJD: disease phenotype determined by a DNA polymorphism Science 1992 258: 806\u2013808","journal-title":"Science"},{"key":"BF4000790_CR27","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1098\/rstb.1994.0034","volume":"343","author":"T Kitamoto","year":"1994","unstructured":"Kitamoto T, Tateishi J . Human prion disease with variant protein Philos Trans R Soc Lond B Biol Sci 1994 343: 391\u2013398","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"BF4000790_CR28","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1016\/S0140-6736(05)78358-6","volume":"351","author":"S Shibuya","year":"1998","unstructured":"Shibuya S, Higuchi J, Shin R-W, Tateishi J, Kitamoto T . Protective prion protein polymorphisms against sporadic Creutzfeldt\u2013Jakob disease Lancet 1998 351: 419","journal-title":"Lancet"},{"key":"BF4000790_CR29","first-page":"888","volume":"58","author":"R Petraroli","year":"1996","unstructured":"Petraroli R, Pocchiari M . Codon 219 polymorphism of PRNP in healthy Caucasians and Creutzfeldt\u2013Jakob disease patients Am J Hum Genet 1996 58: 888\u2013889","journal-title":"Am J Hum Genet"}],"container-title":["Molecular Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/4000790.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/4000790","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/4000790.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T03:46:18Z","timestamp":1648784778000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/4000790"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,12,14]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,1,1]]}},"alternative-id":["BF4000790"],"URL":"https:\/\/doi.org\/10.1038\/sj.mp.4000790","relation":{},"ISSN":["1359-4184","1476-5578"],"issn-type":[{"value":"1359-4184","type":"print"},{"value":"1476-5578","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,12,14]]},"assertion":[{"value":"20 March 2000","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 July 2000","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 July 2000","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 December 2000","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}