{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T19:55:21Z","timestamp":1792266921769,"version":"4.4.0"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2007,5,8]],"date-time":"2007-05-08T00:00:00Z","timestamp":1178582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2007,5,8]],"date-time":"2007-05-08T00:00:00Z","timestamp":1178582400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Psychiatry"],"published-print":{"date-parts":[[2008,2]]},"DOI":"10.1038\/sj.mp.4002012","type":"journal-article","created":{"date-parts":[[2007,5,8]],"date-time":"2007-05-08T03:47:26Z","timestamp":1178596046000},"page":"197-207","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":584,"title":["A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder"],"prefix":"10.1038","volume":"13","author":[{"given":"A E","family":"Baum","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Akula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Cabanero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Cardona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W","family":"Corona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Klemens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T G","family":"Schulze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Cichon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Rietschel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M M","family":"N\u00f6then","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Georgi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Schumacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Schwarz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Abou Jamra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"H\u00f6fels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Propping","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Satagopan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S D","family":"Detera-Wadleigh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Hardy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F J","family":"McMahon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"NIMH Genetics Initiative Bipolar Disorder Consortium","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2007,5,8]]},"reference":[{"key":"BF4002012_CR1","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1126\/science.273.5281.1516","volume":"273","author":"N Risch","year":"1996","unstructured":"Risch N, Merikangas K . The future of genetic studies of complex human diseases. Science 1996; 273: 1516\u20131517.","journal-title":"Science"},{"key":"BF4002012_CR2","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1080\/09540260400014377","volume":"16","author":"SD Detera-Wadleigh","year":"2004","unstructured":"Detera-Wadleigh SD, McMahon FJ . Genetic association studies in mood disorders: issues and promise. Int Rev Psychiatry 2004; 16: 301\u2013310.","journal-title":"Int Rev Psychiatry"},{"key":"BF4002012_CR3","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1038\/nrg1962","volume":"7","author":"E Jorgenson","year":"2006","unstructured":"Jorgenson E, Witte JS . A gene-centric approach to genome-wide association studies. Nat Rev Genet 2006; 7: 885\u2013891.","journal-title":"Nat Rev Genet"},{"key":"BF4002012_CR4","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.1101\/gr.4244005","volume":"15","author":"AG Clark","year":"2005","unstructured":"Clark AG, Boerwinkle E, Hixson J, Sing CF . Determinants of the success of whole-genome association testing. Genome Res 2005; 15: 1463\u20131467.","journal-title":"Genome Res"},{"key":"BF4002012_CR5","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1038\/nrg930","volume":"3","author":"P Sham","year":"2002","unstructured":"Sham P, Bader JS, Craig I, O'Donovan M, Owen M . DNA Pooling: a tool for large-scale association studies. Nat Rev Genet 2002; 3: 862\u2013871.","journal-title":"Nat Rev Genet"},{"key":"BF4002012_CR6","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1038\/sj.gene.6364359","volume":"8","author":"S Steer","year":"2007","unstructured":"Steer S, Abkevich V, Gutin A, Cordell HJ, Gendall KL, Merriman ME et al. Genomic DNA pooling for whole-genome association scans in complex disease: empirical demonstration of efficacy in rheumatoid arthritis. Genes Immun 2007; 8: 57\u201368.","journal-title":"Genes Immun"},{"key":"BF4002012_CR7","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1086\/510686","volume":"80","author":"JV Pearson","year":"2007","unstructured":"Pearson JV, Huentelman MJ, Halperin RF, Tembe WD, Melquist S, Homer N et al. Identification of the genetic basis for complex disorders by use of pooling-based genomewide single-nucleotide-polymorphism association studies. Am J Hum Genet 2007; 80: 126\u2013139.","journal-title":"Am J Hum Genet"},{"key":"BF4002012_CR8","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1001\/archpsyc.1994.03950110009002","volume":"51","author":"JI Nurnberger Jr","year":"1994","unstructured":"Nurnberger Jr JI, Blehar MC, Kaufmann CA, York-Cooler C, Simpson SG, Harkavy-Friedman J et al. Diagnostic interview for genetic studies. Rationale, unique features, and training. NIMH Genetics Initiative. Arch Gen Psychiatry 1994; 51: 849\u2013859.","journal-title":"Arch Gen Psychiatry"},{"key":"BF4002012_CR9","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1093\/bioinformatics\/17.8.742","volume":"17","author":"GR Abecasis","year":"2001","unstructured":"Abecasis GR, Cherny SS, Cookson WO, Cardon LR . GRR: graphical representation of relationship errors. Bioinformatics 2001; 17: 742\u2013743.","journal-title":"Bioinformatics"},{"key":"BF4002012_CR10","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1093\/genetics\/155.2.945","volume":"155","author":"JK Pritchard","year":"2000","unstructured":"Pritchard JK, Stephens M, Donnelly P . Inference of population structure using multilocus genotype data. Genetics 2000; 155: 945\u2013959.","journal-title":"Genetics"},{"key":"BF4002012_CR11","doi-asserted-by":"publisher","first-page":"2933","DOI":"10.1093\/hmg\/10.25.2933","volume":"10","author":"S Cichon","year":"2001","unstructured":"Cichon S, Schumacher J, Muller DJ, Hurter M, Windemuth C, Strauch K et al. A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8q. Hum Mol Genet 2001; 10: 2933\u20132944.","journal-title":"Hum Mol Genet"},{"key":"BF4002012_CR12","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1001\/archpsyc.1982.04290080001001","volume":"39","author":"JF Leckman","year":"1982","unstructured":"Leckman JF, Sholomskas D, Thompson WD, Belanger A, Weissman MM . Best estimate of lifetime psychiatric diagnosis: a methodological study. Arch Gen Psychiatry 1982; 39: 879\u2013883.","journal-title":"Arch Gen Psychiatry"},{"key":"BF4002012_CR13","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/j.biopsych.2004.11.027","volume":"57","author":"B Hoefgen","year":"2005","unstructured":"Hoefgen B, Schulze TG, Ohlraun S, von Widdern O, Hofels S, Gross M et al. The power of sample size and homogenous sampling: association between the 5-HTTLPR serotonin transporter polymorphism and major depressive disorder. Biol Psychiatry 2005; 57: 247\u2013251.","journal-title":"Biol Psychiatry"},{"key":"BF4002012_CR14","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1159\/000083538","volume":"58","author":"H Fangerau","year":"2004","unstructured":"Fangerau H, Ohlraun S, Granath RO, Nothen MM, Rietschel M, Schulze TG . Computer-assisted phenotype characterization for genetic research in psychiatry. Hum Hered 2004; 58: 122\u2013130.","journal-title":"Hum Hered"},{"key":"BF4002012_CR15","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1093\/bioinformatics\/19.1.149","volume":"19","author":"S Purcell","year":"2003","unstructured":"Purcell S, Cherny SS, Sham PC . Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 2003; 19: 149\u2013150.","journal-title":"Bioinformatics"},{"key":"BF4002012_CR16","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1046\/j.1469-1809.2002.00125.x","volume":"66","author":"BJ Barratt","year":"2002","unstructured":"Barratt BJ, Payne F, Rance HE, Nutland S, Todd JA, Clayton DG . Identification of the sources of error in allele frequency estimations from pooled DNA indicates an optimal experimental design. Ann Hum Genet 2002; 66: 393\u2013405.","journal-title":"Ann Hum Genet"},{"key":"BF4002012_CR17","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1080\/07853890310021724","volume":"36","author":"N Norton","year":"2004","unstructured":"Norton N, Williams NM, O'Donovan MC, Owen MJ . DNA pooling as a tool for large-scale association studies in complex traits. Ann Med 2004; 36: 146\u2013152.","journal-title":"Ann Med"},{"key":"BF4002012_CR18","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1002\/biot.200600213","volume":"2","author":"FJ Steemers","year":"2007","unstructured":"Steemers FJ, Gunderson KL . Whole genome genotyping technologies on the BeadArray platform. Biotechnol J 2007; 2: 41\u201349.","journal-title":"Biotechnol J"},{"key":"BF4002012_CR19","unstructured":"Klemens B . Modeling with Data: Modern Statistical Computing with C. Princeton University Press: Princeton, NJ; forthcoming."},{"key":"BF4002012_CR20","doi-asserted-by":"publisher","first-page":"1681","DOI":"10.1093\/bioinformatics\/18.12.1681","volume":"18","author":"A Riva","year":"2002","unstructured":"Riva A, Kohane IS . SNPper: retrieval and analysis of human SNPs. Bioinformatics 2002; 18: 1681\u20131685.","journal-title":"Bioinformatics"},{"key":"BF4002012_CR21","doi-asserted-by":"publisher","first-page":"3445","DOI":"10.1093\/bioinformatics\/bti529","volume":"21","author":"JE Wigginton","year":"2005","unstructured":"Wigginton JE, Abecasis GR . PEDSTATS: descriptive statistics, graphics and quality assessment for gene mapping data. Bioinformatics 2005; 21: 3445\u20133447.","journal-title":"Bioinformatics"},{"key":"BF4002012_CR22","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1002\/gepi.10252","volume":"25","author":"F Dudbridge","year":"2003","unstructured":"Dudbridge F . Pedigree disequilibrium tests for multilocus haplotypes. Genet Epidemiol 2003; 25: 115\u2013121.","journal-title":"Genet Epidemiol"},{"key":"BF4002012_CR23","volume-title":"UNPHASED User Guide. Technical Report 2006\/5","author":"F Dudbridge","year":"2006","unstructured":"Dudbridge F . UNPHASED User Guide. Technical Report 2006\/5. MRC Biostatistics Unit: Cambridge, UK, 2006."},{"key":"BF4002012_CR24","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1111\/j.0006-341X.1999.00997.x","volume":"55","author":"B Devlin","year":"1999","unstructured":"Devlin B, Roeder K . Genomic control for association studies. Biometrics 1999; 55: 997\u20131004.","journal-title":"Biometrics"},{"key":"BF4002012_CR25","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1038\/nrg1916","volume":"7","author":"DJ Balding","year":"2006","unstructured":"Balding DJ . A tutorial on statistical methods for population association studies. Nat Rev Genet 2006; 7: 781\u2013791.","journal-title":"Nat Rev Genet"},{"key":"BF4002012_CR26","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1159\/000095850","volume":"62","author":"M Steffens","year":"2006","unstructured":"Steffens M, Lamina C, Illig T, Bettecken T, Vogler R, Entz P et al. SNP-based analysis of genetic substructure in the German population. Hum Hered 2006; 62: 20\u201329.","journal-title":"Hum Hered"},{"key":"BF4002012_CR27","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1086\/500026","volume":"78","author":"K Roeder","year":"2006","unstructured":"Roeder K, Bacanu SA, Wasserman L, Devlin B . Using linkage genome scans to improve power of association in genome scans. Am J Hum Genet 2006; 78: 243\u2013252.","journal-title":"Am J Hum Genet"},{"key":"BF4002012_CR28","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1002\/gepi.20164","volume":"30","author":"L Sun","year":"2006","unstructured":"Sun L, Craiu RV, Paterson AD, Bull SB . Stratified false discovery control for large-scale hypothesis testing with application to genome-wide association studies. Genet Epidemiol 2006; 30: 519\u2013530.","journal-title":"Genet Epidemiol"},{"key":"BF4002012_CR29","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/j.biopsych.2006.01.019","volume":"60","author":"SD Detera-Wadleigh","year":"2006","unstructured":"Detera-Wadleigh SD, McMahon FJ . G72\/G30 in schizophrenia and bipolar disorder: review and meta analysis. Biol Psychiatry 2006; 60: 106\u2013114.","journal-title":"Biol Psychiatry"},{"key":"BF4002012_CR30","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1038\/sj.mp.4001012","volume":"7","author":"JA Badner","year":"2002","unstructured":"Badner JA, Gershon ES . Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia. Mol Psychiatry 2002; 7: 405\u2013411.","journal-title":"Mol Psychiatry"},{"key":"BF4002012_CR31","doi-asserted-by":"publisher","first-page":"1834","DOI":"10.1001\/jama.1989.03430130110043","volume":"262","author":"MJ Berridge","year":"1989","unstructured":"Berridge MJ . The Albert Lasker Medical Awards. Inositol trisphosphate, calcium, lithium, and cell signaling. JAMA 1989; 262: 1834\u20131841.","journal-title":"JAMA"},{"key":"BF4002012_CR32","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1038\/ncb1405","volume":"8","author":"Y Funato","year":"2006","unstructured":"Funato Y, Michiue T, Asashima M, Miki H . The thioredoxin-related redox-regulating protein nucleoredoxin inhibits Wnt-beta-catenin signalling through dishevelled. Nat Cell Biol 2006; 8: 501\u2013508.","journal-title":"Nat Cell Biol"},{"key":"BF4002012_CR33","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1038\/nm0602-557","volume":"8","author":"JT Coyle","year":"2002","unstructured":"Coyle JT, Manji HK . Getting balance: drugs for bipolar disorder share target. Nat Med 2002; 8: 557\u2013558.","journal-title":"Nat Med"},{"key":"BF4002012_CR34","doi-asserted-by":"publisher","first-page":"2152","DOI":"10.1016\/S0960-9822(02)01358-1","volume":"12","author":"RL Nash HA Scott","year":"2002","unstructured":"Nash HA Scott RL, Lear BC Allada R . An unusual cation channel mediates photic control of locomotion in Drosophila. Curr Biol 2002; 12: 2152\u20132158.","journal-title":"Curr Biol"},{"key":"BF4002012_CR35","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1086\/427836","volume":"76","author":"T Venken","year":"2005","unstructured":"Venken T, Claes S, Slyjis S, Paterson AD, van Duijn C, Adolfsson R et al. Genomewide scan for affective disorder susceptibility locs in families of a northern Swedish isolated population. Am J Hum Genet 2005; 76: 237\u2013248.","journal-title":"Am J Hum Genet"},{"key":"BF4002012_CR36","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1038\/ng1208","volume":"34","author":"P Mburu","year":"2003","unstructured":"Mburu P, Mustapha M, Varela A, Weil D, El-Amraoui A, Holme RH et al. Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31. Nat Genet 2003; 34: 421\u2013428.","journal-title":"Nat Genet"},{"key":"BF4002012_CR37","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1007\/s00439-006-0304-0","volume":"121","author":"I Ebermann","year":"2007","unstructured":"Ebermann I, Scholl HP, Charbel Issa P, Becirovic E, Lamprecht J, Jurklies B et al. A novel gene for Usher syndrome type 2: mutations in the long isoform of whirlin are associated with retinitis pigmentosa and sensorineural hearing loss. Hum Genet 2007; 121: 203\u2013211.","journal-title":"Hum Genet"},{"key":"BF4002012_CR38","doi-asserted-by":"publisher","first-page":"R262","DOI":"10.1093\/hmg\/ddl205","volume":"15","author":"H Kremer","year":"2006","unstructured":"Kremer H, van Wijk E, Marker T, Wolfrum U, Roepman R . Usher syndrome: molecular links of pathogenesis, proteins and pathways. Hum Mol Genet 2006; 15: R262\u2013R270.","journal-title":"Hum Mol Genet"},{"key":"BF4002012_CR39","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1097\/00006982-198707040-00009","volume":"7","author":"L Piazza","year":"1987","unstructured":"Piazza L, Fishman GA, Kaplan RD, Horowitz AL, Hindo WA, Mafee MF . Magnetic resonance imaging of central nervous system defects in Usher's syndrome. Retina 1987; 7: 241\u2013245.","journal-title":"Retina"},{"key":"BF4002012_CR40","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1136\/jnnp.51.7.987","volume":"51","author":"J Koizumi","year":"1988","unstructured":"Koizumi J, Ofuku K, Sakuma K, Shiraishi H, Iio M, Nawano S . CNS changes in Usher's syndrome with mental disorder: CT, MRI and PET findings. J Neurol Neurosurg Psychiatry 1988; 51: 987\u2013990.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"BF4002012_CR41","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1176\/ajp.156.8.1267","volume":"156","author":"NA Shapira","year":"1999","unstructured":"Shapira NA, DelBello MP, Goldsmith TD, Rosenberger BM, Keck Jr PE . Evaluation of bipolar disorder in inpatients with prelingual deafness. Am J Psychiatry 1999; 156: 1267\u20131269.","journal-title":"Am J Psychiatry"},{"key":"BF4002012_CR42","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1038\/ng0496-427","volume":"12","author":"DH Blackwood","year":"1996","unstructured":"Blackwood DH, He L, Morris SW, McLean A, Whitton C, Thomson M et al. A locus for bipolar affective disorder on chromosome 4p. Nat Genet 1996; 12: 427\u2013430.","journal-title":"Nat Genet"},{"key":"BF4002012_CR43","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/S0925-4773(00)00523-2","volume":"100","author":"M Rezgaoui","year":"2001","unstructured":"Rezgaoui M, Hermey G, Riedel IB, Hampe W, Schaller HC, Hermans-Borgmeyer I . Identification of SorCS2, a novel member of the VPS10 domain containing receptor family, prominently expressed in the developing mouse brain. Mech Dev 2001; 100: 335\u2013338.","journal-title":"Mech Dev"},{"key":"BF4002012_CR44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1469-1809.1967.tb02015.x","volume":"31","author":"DS Falconer","year":"1967","unstructured":"Falconer DS . The inheritance of liability to diseases with variable age of onset, with particular reference to diabetes mellitus. Ann Hum Genet 1967; 31: 1\u201320.","journal-title":"Ann Hum Genet"},{"key":"BF4002012_CR45","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1086\/376547","volume":"73","author":"R Segurado","year":"2003","unstructured":"Segurado R, Detera-Wadleigh SD, Levinson DF, Lewis CM, Gill M, Nurnberger Jr JI et al. Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: bipolar disorder. Am J Hum Genet 2003; 73: 49\u201362.","journal-title":"Am J Hum Genet"},{"key":"BF4002012_CR46","first-page":"39","volume":"29","author":"E Slater","year":"1936","unstructured":"Slater E . The inheritance of manic-depressive insanity. Proc R Soc Med 1936; 29: 39\u201348.","journal-title":"Proc R Soc Med"},{"key":"BF4002012_CR47","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1037\/0033-2909.108.1.109","volume":"108","author":"SV Faraone","year":"1990","unstructured":"Faraone SV, Kremen WS, Tsuang MT . Genetic transmission of major affective disorders: quantitative models and linkage analyses. Psychol Bull 1990; 108: 109\u2013127.","journal-title":"Psychol Bull"},{"key":"BF4002012_CR48","first-page":"47","volume":"69","author":"RE Pyeritz","year":"1991","unstructured":"Pyeritz RE . Formal genetics in humans: Mendelian and non-Mendelian inheritance. Res Publ Assoc Res Nerv Ment Dis 1991; 69: 47\u201373.","journal-title":"Res Publ Assoc Res Nerv Ment Dis"},{"key":"BF4002012_CR49","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/0165-0327(79)90011-9","volume":"1","author":"F Negri","year":"1979","unstructured":"Negri F, Melica AM, Zuliani R, Smeraldi E . Assortative mating and affective disorders. J Affect Disord 1979; 1: 247\u2013253.","journal-title":"J Affect Disord"},{"key":"BF4002012_CR50","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1080\/07853890600946500","volume":"38","author":"BS Pickard","year":"2006","unstructured":"Pickard BS, Pieper AA, Porteous DJ, Blackwood DH, Muir WJ . The NPAS3 gene \u2013 emerging evidence for a role in psychiatric illness. Ann Med 2006; 38: 439\u2013448.","journal-title":"Ann Med"},{"key":"BF4002012_CR51","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1086\/497703","volume":"77","author":"MD Fallin","year":"2005","unstructured":"Fallin MD, Lasseter VK, Avramopoulos D, Nicodemus KK, Wolyniec PS, McGrath JA et al. Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios. Am J Hum Genet 2005; 77: 918\u2013936.","journal-title":"Am J Hum Genet"},{"key":"BF4002012_CR52","volume-title":"Annual Meeting of The American Society of Human Genetics","author":"S Buervenich","year":"2003","unstructured":"Buervenich S, Detera-Wadleigh SD, Akula N, Thomas CJM, Kassem L, Rezvani A et al. Fine mapping on chromosome 6q in the NIMH Genetics Initiative bipolar pedigrees [Abstract 1882]. Annual Meeting of The American Society of Human Genetics. Los Angeles, CA, 2003 (http:\/\/genetics.faseb.org\/genetics\/ashg03s\/index.shtml)."},{"key":"BF4002012_CR53","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1038\/sj.mp.4001388","volume":"9","author":"D Avramopoulos","year":"2004","unstructured":"Avramopoulos D, Willour VL, Zandi PP, Huo Y, MacKinnon DF, Potash JB et al. Linkage of bipolar affective disorder on chromosome 8q24: follow-up and parametric analysis. Mol Psychiatry 2004; 9: 191\u2013196.","journal-title":"Mol Psychiatry"},{"key":"BF4002012_CR54","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1016\/j.cell.2006.03.032","volume":"125","author":"J Lim","year":"2006","unstructured":"Lim J, Hao T, Shaw C, Patel AJ, Szabo G, Rual JF et al. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Cell 2006; 125: 801\u2013814.","journal-title":"Cell"}],"container-title":["Molecular Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/4002012.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/4002012","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/4002012.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,14]],"date-time":"2024-02-14T04:02:27Z","timestamp":1707883347000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/4002012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5,8]]},"references-count":54,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,2]]}},"alternative-id":["BF4002012"],"URL":"https:\/\/doi.org\/10.1038\/sj.mp.4002012","relation":{},"ISSN":["1359-4184","1476-5578"],"issn-type":[{"value":"1359-4184","type":"print"},{"value":"1476-5578","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,5,8]]},"assertion":[{"value":"19 February 2007","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 March 2007","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 March 2007","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 May 2007","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}