{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T18:33:17Z","timestamp":1717180397968},"reference-count":26,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,10,7]],"date-time":"2016-10-07T00:00:00Z","timestamp":1475798400000},"content-version":"vor","delay-in-days":3263,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular Therapy"],"published-print":{"date-parts":[[2007,11]]},"DOI":"10.1038\/sj.mt.6300276","type":"journal-article","created":{"date-parts":[[2007,8,7]],"date-time":"2007-08-07T11:45:16Z","timestamp":1186487116000},"page":"1924-1930","source":"Crossref","is-referenced-by-count":6,"title":["Vegf or EphA2 Antisense Polyamide-nucleic acids; Vascular Localization and Suppression of Retinal Neovascularization"],"prefix":"10.1016","volume":"15","author":[{"given":"Jikui","family":"Shen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina M","family":"Hatara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean F","family":"Hackett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter A","family":"Campochiaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1038\/sj.mt.6300276_bib1","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1126\/science.1962210","article-title":"Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide","volume":"254","author":"Nielsen","year":"1991","journal-title":"Science"},{"key":"10.1038\/sj.mt.6300276_bib2","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1038\/365566a0","article-title":"PNA hybridizes to complementary oligonucleotides obeying the Watson\u2013Crick hydrogen-bonding rules","volume":"365","author":"Egholm","year":"1993","journal-title":"Nature"},{"key":"10.1038\/sj.mt.6300276_bib3","doi-asserted-by":"crossref","first-page":"7857","DOI":"10.1016\/0040-4039(96)01750-9","article-title":"An approach towards the synthesis of oligomers containing a N-2-hydroxyethyl-aminomethylphosphonate backbone: a novel PNA analogue","volume":"43","author":"van der Laan","year":"1996","journal-title":"Tetrahedron Lett"},{"key":"10.1038\/sj.mt.6300276_bib4","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1093\/nar\/26.2.566","article-title":"Synthesis and evaluation of some properties of chimeric oligomers containing PNA and phosphono-PNA residues","volume":"26","author":"Efimov","year":"1998","journal-title":"Nucleic Acids Res"},{"key":"10.1038\/sj.mt.6300276_bib5","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1081\/NCN-100002316","article-title":"PNA-related oligonucleotide mimics and their evaluation for nucleic acid hybridization studies and analysis","volume":"20","author":"Efimov","year":"2001","journal-title":"Nucleosides Nucleotides Nucleic Acids"},{"key":"10.1038\/sj.mt.6300276_bib6","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/sj.gt.3302641","article-title":"Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1","volume":"13","author":"Shen","year":"2005","journal-title":"Gene Ther"},{"key":"10.1038\/sj.mt.6300276_bib7","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1096\/fj.05-5046fje","article-title":"Vasohibin is up-regulated by VEGF in the retina and suppresses VEGF receptor 2 and retinal neovascularization","volume":"20","author":"Shen","year":"2006","journal-title":"FASEB J"},{"key":"10.1038\/sj.mt.6300276_bib8","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1002\/jcp.20819","article-title":"Reduction of p66Shc suppresses oxidative damage in retinal pigmented epithelial cells and retina","volume":"209","author":"Wu","year":"2006","journal-title":"J Cell Physiol"},{"key":"10.1038\/sj.mt.6300276_bib9","first-page":"210","article-title":"Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model","volume":"9","author":"Reich","year":"2003","journal-title":"Mol Vis"},{"key":"10.1038\/sj.mt.6300276_bib10","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/0092-8674(95)90425-5","article-title":"In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases","volume":"82","author":"Drescher","year":"1995","journal-title":"Cell"},{"key":"10.1038\/sj.mt.6300276_bib11","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0959-4388(97)80123-7","article-title":"The Eph family in retinal axon guidance","volume":"7","author":"Drescher","year":"1997","journal-title":"Curr Opin Neurobiol"},{"key":"10.1038\/sj.mt.6300276_bib12","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0925-4773(98)00142-7","article-title":"Ephrin-A1 is expressed at sites of vascular development in the mouse","volume":"77","author":"McBride","year":"1998","journal-title":"Mech Dev"},{"key":"10.1038\/sj.mt.6300276_bib13","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1101\/gad.13.3.295","article-title":"Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial\/venous domains, vascular morphogenesis, and spouting angiogenesis","volume":"13","author":"Adams","year":"1999","journal-title":"Genes Dev"},{"key":"10.1038\/sj.mt.6300276_bib14","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1126\/science.7536959","article-title":"Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis","volume":"268","author":"Pandey","year":"1995","journal-title":"Science"},{"key":"10.1038\/sj.mt.6300276_bib15","doi-asserted-by":"crossref","first-page":"6043","DOI":"10.1038\/sj.onc.1204004","article-title":"The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization","volume":"19","author":"Ogawa","year":"2000","journal-title":"Oncogene"},{"key":"10.1038\/sj.mt.6300276_bib16","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.exer.2005.09.004","article-title":"Inhibition of retinal neovascularization by soluble EphA2 receptor","volume":"82","author":"Chen","year":"2006","journal-title":"Exp Eye Res"},{"key":"10.1038\/sj.mt.6300276_bib17","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1006\/exer.1996.0239","article-title":"Intravitreal sustained release of VEGF causes retinal neovascularization in rabbits and breakdown of the blood-retinal barrier in rabbits and primates","volume":"64","author":"Ozaki","year":"1997","journal-title":"Exp Eye Res"},{"key":"10.1038\/sj.mt.6300276_bib18","first-page":"281","article-title":"Transgenic mice with increased expression of vascular endothelial growth factor in the retina: a new model of intraretinal and subretinal neovascularization","volume":"151","author":"Okamoto","year":"1997","journal-title":"Am J Pathol"},{"key":"10.1038\/sj.mt.6300276_bib19","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/S0002-9440(10)64773-6","article-title":"Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularization","volume":"156","author":"Ozaki","year":"2000","journal-title":"Am J Pathol"},{"key":"10.1038\/sj.mt.6300276_bib20","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1073\/pnas.012074399","article-title":"Selective induction of neuropilin-1 by vascular endothelial growth factor (VEGF): a mechanism contributing to VEGF-induced angiogenesis","volume":"99","author":"Oh","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/sj.mt.6300276_bib21","first-page":"474","article-title":"Localization of VEGF receptor-2 (KDR\/Flk-1) and effects of blocking it in oxygen-induced retinopathy","volume":"43","author":"McLeod","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1038\/sj.mt.6300276_bib22","doi-asserted-by":"crossref","first-page":"12","DOI":"10.2119\/2004-00017.Campochiaro","article-title":"Deficiency of neuropilin 2 suppresses VEGF-induced retinal neovascularization","volume":"10","author":"Shen","year":"2004","journal-title":"Mol Med"},{"key":"10.1038\/sj.mt.6300276_bib23","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1096\/fj.04-2209fje","article-title":"Different effects of angiopoietin 2 in different vascular beds in the eye; new vessels are most sensitive","volume":"19","author":"Oshima","year":"2005","journal-title":"FASEB J"},{"key":"10.1038\/sj.mt.6300276_bib24","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1038\/sj.gt.3302230","article-title":"Angiopoietin 1 inhibits ocular neovascularization and breakdown of the blood-retinal barrier","volume":"11","author":"Nambu","year":"2004","journal-title":"Gene Ther"},{"key":"10.1038\/sj.mt.6300276_bib25","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/jcp.20292","article-title":"Angiopoietin 1 prevents retinal detachment in an aggressive model of proliferative retinopathy, but has no effect on established neovascularization","volume":"204","author":"Nambu","year":"2005","journal-title":"J Cell Physiol"},{"key":"10.1038\/sj.mt.6300276_bib26","first-page":"101","article-title":"Oxygen-induced retinopathy in the mouse","volume":"35","author":"Smith","year":"1994","journal-title":"Invest Ophthalmol Vis Sci"}],"container-title":["Molecular Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525001616326545?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525001616326545?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T20:16:22Z","timestamp":1556741782000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525001616326545"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11]]},"references-count":26,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["S1525001616326545"],"URL":"https:\/\/doi.org\/10.1038\/sj.mt.6300276","relation":{},"ISSN":["1525-0016"],"issn-type":[{"value":"1525-0016","type":"print"}],"subject":[],"published":{"date-parts":[[2007,11]]}}}