{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T02:47:44Z","timestamp":1792205264794,"version":"4.4.0"},"reference-count":72,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2005,1,26]],"date-time":"2005-01-26T00:00:00Z","timestamp":1106697600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropsychopharmacol"],"published-print":{"date-parts":[[2005,4]]},"DOI":"10.1038\/sj.npp.1300610","type":"journal-article","created":{"date-parts":[[2005,2,2]],"date-time":"2005-02-02T05:37:09Z","timestamp":1107322629000},"page":"669-682","source":"Crossref","is-referenced-by-count":277,"title":["Interactions between Serotonin and Dopamine in the Control of Impulsive Choice in Rats: Therapeutic Implications for Impulse Control Disorders"],"prefix":"10.1038","volume":"30","author":[{"given":"Catharine A","family":"Winstanley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David E H","family":"Theobald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey W","family":"Dalley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trevor W","family":"Robbins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2005,1,26]]},"reference":[{"key":"BF1300610_CR1","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1111\/j.2042-7158.1990.tb05410.x","volume":"42","author":"S Ahlenius","year":"1990","unstructured":"Ahlenius S, Hillegaart V, Wijkstrom A (1990). Increased dopamine turnover in the ventral striatum by 8-OH-DPAT administration in the rat. J Pharm Pharmacol 42: 285\u2013288.","journal-title":"J Pharm Pharmacol"},{"key":"BF1300610_CR2","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/S0079-6123(08)62678-3","volume":"85","author":"GE Alexander","year":"1990","unstructured":"Alexander GE, Crutcher MD, DeLong MR (1990). Basal ganglia-thalamocortical circuits\u2014parallel substrates for motor, oculomotor, prefrontal and limbic functions. Prog Brain Res 85: 119\u2013146.","journal-title":"Prog Brain Res"},{"key":"BF1300610_CR3","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1111\/j.1748-1716.1993.tb09584.x","volume":"148","author":"L Arborelius","year":"1993","unstructured":"Arborelius L, Nomikos GG, Hacksell U, Svensson TH (1993). (R)-8-Oh-Dpat preferentially increases dopamine release in rat medial prefrontal cortex. Acta Physiol Scand 148: 465\u2013466.","journal-title":"Acta Physiol Scand"},{"key":"BF1300610_CR4","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1016\/S0306-4522(03)00219-7","volume":"119","author":"A Balcioglu","year":"2003","unstructured":"Balcioglu A, Zhang K, Tarazi FI (2003). Dopamine depletion abolishes apomorphine- and amphetamine-induced increases in extracellular serotonin levels in the striatum of conscious rats: a microdialysis study. Neuroscience 119: 1045\u20131053.","journal-title":"Neuroscience"},{"key":"BF1300610_CR5","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/S0028-3908(99)00010-6","volume":"38","author":"NM Barnes","year":"1999","unstructured":"Barnes NM, Sharp T (1999). A review of central 5-HT receptors and their function. Neuropharmacology 38: 1083\u20131152.","journal-title":"Neuropharmacology"},{"key":"BF1300610_CR6","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1007\/PL00005485","volume":"146","author":"JC Bizot","year":"1999","unstructured":"Bizot JC, Le Bihan C, Puech AJ, Hamon M, Thiebot MH (1999). Serotonin and tolerance to delay of reward in rats. Psychopharmacology 146: 400\u2013412.","journal-title":"Psychopharmacology"},{"key":"BF1300610_CR7","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1111\/j.1471-4159.1975.tb11693.x","volume":"24","author":"A Bjorkland","year":"1975","unstructured":"Bjorkland A, Baumgarten HD, Rensch A (1975). 5,7-Dihydroxytryptamine: improvement of its selectivity for serotonin neurons in the CNS by treatment with desipramine. J Neurochem 24: 833\u2013835.","journal-title":"J Neurochem"},{"key":"BF1300610_CR8","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/0304-3940(92)90308-T","volume":"137","author":"G Bonvento","year":"1992","unstructured":"Bonvento G, Scatton B, Claustre Y, Rouquier L (1992). Effect of local injection of 8-OH-DPAT into the dorsal or median raphe nuclei on extracellular levels of serotonin in serotonergic projection areas in the rat brain. Neurosci Lett 137: 101\u2013104.","journal-title":"Neurosci Lett"},{"key":"BF1300610_CR9","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/0166-4328(93)90113-5","volume":"55","author":"LH Burns","year":"1993","unstructured":"Burns LH, Robbins TW, Everitt BJ (1993). Differential effects of excitotoxic lesions of the basolateral amygdala, ventral subiculum and prefrontal cortex on responding with conditioned reinforcement and locomotor activity potentiated by intra-accumbens infusions of amphetamine. Behav Brain Res 55: 167\u2013183.","journal-title":"Behav Brain Res"},{"key":"BF1300610_CR10","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1007\/BF02246039","volume":"104","author":"M Cador","year":"1991","unstructured":"Cador M, Taylor JR, Robbins TW (1991). Potentiation of the effects of reward-related stimuli by dopaminergic-dependent mechanisms in the nucleus-accumbens. Psychopharmacology 104: 377\u2013385.","journal-title":"Psychopharmacology"},{"key":"BF1300610_CR11","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/S0006-8993(97)00777-4","volume":"771","author":"A Campbell","year":"1997","unstructured":"Campbell A, Villavincencio AT, Yeghiayan SK, Balikian R, Baldessarini RJ (1997). Mapping of locomotor behavioral arousal induced by microinjections of dopamine within nucleus accumbens septi of rat forebrain. Brain Res 771: 55\u201362.","journal-title":"Brain Res"},{"key":"BF1300610_CR12","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1037\/0735-7044.116.4.553","volume":"116","author":"RN Cardinal","year":"2002","unstructured":"Cardinal RN, Parkinson JA, Lachenal G, Halkerston KM, Rudarakanchana N, Hall J et al (2002). Effects of selective excitotoxic lesions of the nucleus accumbens core, anterior cingulate cortex, and central nucleus of the amygdala on autoshaping performance in rats. Behav Neurosci 116: 533\u2013567.","journal-title":"Behav Neurosci"},{"key":"BF1300610_CR13","doi-asserted-by":"publisher","first-page":"2499","DOI":"10.1126\/science.1060818","volume":"292","author":"RN Cardinal","year":"2001","unstructured":"Cardinal RN, Pennicott DR, Sugathapala CL, Robbins TW, Everitt BJ (2001). Impulsive choice induced in rats by lesions of the nucleus accumbens core. Science 292: 2499\u20132501.","journal-title":"Science"},{"key":"BF1300610_CR14","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1007\/s002130000536","volume":"152","author":"RN Cardinal","year":"2000","unstructured":"Cardinal RN, Robbins TW, Everitt BJ (2000). The effects of d-amphetamine, chlordiazepoxide, alpha-flupenthixol and behavioral manipulations on choice of signalled and unsignalled delayed reinforcement in rats. Psychopharmacology 152: 362\u2013375.","journal-title":"Psychopharmacology"},{"key":"BF1300610_CR15","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/S0166-4328(97)00178-2","volume":"94","author":"MP Carey","year":"1998","unstructured":"Carey MP, Diewald LM, Esposito FJ, Pellicano MP, Carnevale UAG, Sergeant JA et al (1998). Differential distribution, affinity and plasticity of dopamine D-1 and D-2 receptors in the target sites of the mesolimbic system in an animal model of ADHD. Behav Brain Res 94: 173\u2013185.","journal-title":"Behav Brain Res"},{"key":"BF1300610_CR16","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/0091-3057(87)90485-0","volume":"27","author":"GD Carr","year":"1987","unstructured":"Carr GD, White N (1987). Effects of systemic and intracranial amphetamine injections on behavior in the open field: a detailed analysis. Pharmacol Biochem Behav 27: 113\u2013122.","journal-title":"Pharmacol Biochem Behav"},{"key":"BF1300610_CR17","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/0006-8993(91)90748-K","volume":"561","author":"DT Chalmers","year":"1991","unstructured":"Chalmers DT, Watson SJ (1991). Comparative anatomical distribution of 5-HT1A receptor mRNA and 5-HT1A binding in rat brain\u2014a combined in situ hybridisation\/in vitro receptor autoradiographic study. Brain Res 561: 51\u201360.","journal-title":"Brain Res"},{"key":"BF1300610_CR18","doi-asserted-by":"publisher","first-page":"1585","DOI":"10.1046\/j.1471-4159.1995.64041585.x","volume":"64","author":"N-H Chen","year":"1995","unstructured":"Chen N-H, Reith MEA (1995). Monoamine interactions meausured by microdialysis in the ventral tegmental area of rats treated systemically with (8-hydroxy-2-(di-n-propylamino)-tetralin. J Neurochem 64: 1585\u20131597.","journal-title":"J Neurochem"},{"key":"BF1300610_CR19","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1007\/BF00216011","volume":"91","author":"BJ Cole","year":"1987","unstructured":"Cole BJ, Robbins TW (1987). Amphetamine impairs the discriminative performance of rats with dorsal noradrenergic bundle lesions on a 5-choice serial reaction time task: new evidence for central dopaminergic-noradrenergic interactions. Psychopharmacology 91: 458\u2013466.","journal-title":"Psychopharmacology"},{"key":"BF1300610_CR20","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/S0166-4328(89)80048-8","volume":"33","author":"BJ Cole","year":"1989","unstructured":"Cole BJ, Robbins TW (1989). Effects of 6-hydroxydopamine lesions of the nucleus accumbens septi on performance of a 5-choice serial reaction time task in rats\u2014implications for theories of selective attention and arousal. Behav Brain Res 33: 165\u2013179.","journal-title":"Behav Brain Res"},{"key":"BF1300610_CR21","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1016\/S0306-4522(98)00617-4","volume":"91","author":"MS Cousins","year":"1999","unstructured":"Cousins MS, Trevitt J, Atherton A, Salamone JD (1999). Differential behavioral functions of dopamine in nucleus accumbens and venterolateral striatum: a microdialysis and behavioral investigation. Neuroscience 91: 925\u2013934.","journal-title":"Neuroscience"},{"key":"BF1300610_CR22","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1007\/s00213-002-1078-2","volume":"161","author":"JW Dalley","year":"2002","unstructured":"Dalley JW, Chudasama Y, Theobald DE, Pettifer CL, Fletcher CM, Robbins TW (2002). Nucleus accumbens dopamine and discriminated approach learning: interactive effects of 6-hydroxydopamine lesions and systemic apomorphine administration. Psychopharmacology 161: 425\u2013433.","journal-title":"Psychopharmacology"},{"key":"BF1300610_CR23","first-page":"610","volume":"292","author":"R De La Garza","year":"2000","unstructured":"De La Garza R, Cunningham KA (2000). The effects of the 5-hydroxytryptamine1a agonist 8-hydroxy-2-(di-n-propylamino) tetralin on spontaneous activity, cocaine-induced hyperactivity and behavioral sensitization: a microanalysis of locomotor activity. J Pharmacol Exp Ther 292: 610\u2013617.","journal-title":"J Pharmacol Exp Ther"},{"key":"BF1300610_CR24","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1002\/cne.1147","volume":"433","author":"MD Doherty","year":"2001","unstructured":"Doherty MD, Pickel VM (2001). Targeting of serotonin 1A receptors to dopaminergic neuron within the parabrachial subdivision of the ventral tegmental area. J Comp Neurol 433: 390\u2013400.","journal-title":"J Comp Neurol"},{"key":"BF1300610_CR25","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/0028-3908(94)90071-X","volume":"33","author":"CJ Done","year":"1994","unstructured":"Done CJ, Sharp T (1994). Biochemical evidence for the regulation of central noradrenergic activity by 5-HT1A and 5-HT2 receptors: microdialysis studies in the awake and anaesthetised rat. Neuropharmacology 33: 411\u2013421.","journal-title":"Neuropharmacology"},{"key":"BF1300610_CR26","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1007\/s002130050121","volume":"128","author":"JL Evenden","year":"1996","unstructured":"Evenden JL, Ryan CN (1996). The pharmacology of impulsive behaviour in rats: the effects of drugs on response choice with varying delays of reinforcement. Psychopharmacology 128: 161\u2013170.","journal-title":"Psychopharmacology"},{"key":"BF1300610_CR27","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1007\/PL00005486","volume":"146","author":"JL Evenden","year":"1999","unstructured":"Evenden JL, Ryan CN (1999). The pharmacology of impulsive behaviour in rats: VI the effects of ethanol and selective serotonergic drugs on response choice with varying delays of reinforcement. Psychopharmacology 146: 413\u2013421.","journal-title":"Psychopharmacology"},{"key":"BF1300610_CR28","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1126\/science.283.5400.397","volume":"283","author":"RR Gainetdinov","year":"1999","unstructured":"Gainetdinov RR, Wetsel WC, Jones SR, Levin ED, Jaber M, Caron MG (1999). Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science 283: 397\u2013401.","journal-title":"Science"},{"key":"BF1300610_CR29","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1016\/S0893-133X(99)00035-4","volume":"21","author":"A Gobert","year":"1999","unstructured":"Gobert A, Millan MJ (1999). Modulation of dialysate levels of dopamine, noradrenaline, and serotonin (5-HT) in the frontal cortex of freely-moving rats by (\u2212)-pindolol and in association with 5-HT reuptake alone and in association with 5-HT reuptake inhibtors: comparative roles of beta-adrenergic, 5-HT1A, and 5-HT1B receptors. Neuropsychopharmacology 21: 268\u2013284.","journal-title":"Neuropsychopharmacology"},{"key":"BF1300610_CR30","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1007\/s002109900058","volume":"360","author":"S Herges","year":"1999","unstructured":"Herges S, Taylor DA (1999). Modulation of cocaine-induced locomotor activity, rears and head-bobs by application of WAY100635 into the dorsal and median raphe nuclei of the rat. Naunyn-Schmiedebergs Arch Pharmacol 360: 129\u2013134.","journal-title":"Naunyn-Schmiedebergs Arch Pharmacol"},{"key":"BF1300610_CR31","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/0014-2999(95)00624-9","volume":"287","author":"J Ichikawa","year":"1995","unstructured":"Ichikawa J, Kuroki T, Kitchen MT, Meltzer HY (1995). R(+)-8-OH-DPAT, a 5-HT1A receptor agonist, inhibits amphetamine-induced dopamine release in rat striatum and nucleus accumbens. Eur J Pharmacol 287: 179\u2013184.","journal-title":"Eur J Pharmacol"},{"key":"BF1300610_CR32","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1016\/S0006-8993(99)02346-X","volume":"858","author":"J Ichikawa","year":"2000","unstructured":"Ichikawa J, Meltzer HY (2000). The effect of serotonin (1A) receptor agonism on antipsychotic drug-induced dopamine release in rat striatum and nucleus accumbens. Brain Res 858: 252\u2013263.","journal-title":"Brain Res"},{"key":"BF1300610_CR33","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1016\/0091-3057(92)90422-C","volume":"43","author":"GH Jones","year":"1992","unstructured":"Jones GH, Robbins TW (1992). Differential effects of mesocortical, mesolimbic, and mesostriatal dopamine depletion on spontaneous, conditioned and drig-induced locomotor activity. Pharmacol Biochem Behav 43: 887\u2013895.","journal-title":"Pharmacol Biochem Behav"},{"key":"BF1300610_CR34","first-page":"803","volume":"253","author":"MD Kelland","year":"1990","unstructured":"Kelland MD, Freeman AS, Chiodo LA (1990). Serotonergic afferent regulation of the basic physiology and pharmacological responsiveness of nigrostriatal dopamine neurons. J Pharmacol Exp Ther 253: 803\u2013811.","journal-title":"J Pharmacol Exp Ther"},{"key":"BF1300610_CR35","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/0006-8993(75)90233-4","volume":"94","author":"PH Kelly","year":"1975","unstructured":"Kelly PH, Seviour PW, Iversen SD (1975). Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum. Brain Res 94: 507\u2013522.","journal-title":"Brain Res"},{"key":"BF1300610_CR36","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1007\/s00213-004-1813-y","volume":"175","author":"S Kheramin","year":"2004","unstructured":"Kheramin S, Body S, Ho MY, Velazquez-Martinez DN, Bradshaw CM, Szabadi E et al (2004). Effects of orbital prefrontal cortex dopamine depletion on inter-temporal choice: a quantitative analysis. Psychopharmacology 175: 206\u2013214.","journal-title":"Psychopharmacology"},{"key":"BF1300610_CR37","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1037\/h0077542","volume":"92","author":"G Koob","year":"1978","unstructured":"Koob G, Riley ST, Smith SC, Robbins TW (1978). Effects of 6-hydroxydopamine lesions of the nucleus accumbens septi and olfactory tubercle on feeding, locomotor activity and amphetamine anorexia in the rat. J Comp Physiol Psychol 92: 917\u2013927.","journal-title":"J Comp Physiol Psychol"},{"key":"BF1300610_CR38","doi-asserted-by":"publisher","first-page":"2051","DOI":"10.1523\/JNEUROSCI.09-06-02051.1989","volume":"9","author":"R Kuczenski","year":"1989","unstructured":"Kuczenski R, Segal DS (1989). Concomitant characterisation of behavioral and striatal neurotransmitter response to amphetamine using in vivo microdialysis. J Neurosci 9: 2051\u20132065.","journal-title":"J Neurosci"},{"key":"BF1300610_CR39","doi-asserted-by":"publisher","first-page":"1306","DOI":"10.1523\/JNEUROSCI.15-02-01308.1995","volume":"15","author":"R Kuczenski","year":"1995","unstructured":"Kuczenski R, Segal DS (1995). Hippocampus norepinephrine, caudate dopamine and serotonin, and behavioral responses to the stereoisomers of amphetamine and methamphetamine. J Neurosci 15: 1306\u20131317.","journal-title":"J Neurosci"},{"key":"BF1300610_CR40","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1007\/BF00187252","volume":"93","author":"R Kuczenski","year":"1987","unstructured":"Kuczenski R, Segal DS, Leith NJ, Applegate CD (1987). Effects of amphetamine, methylphenidate, and apomorphine on regional brain serotonin and 5-hydroxyindole acetic acid. Psychopharmacology 93: 329\u2013335.","journal-title":"Psychopharmacology"},{"key":"BF1300610_CR41","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1016\/S0006-8993(96)01111-0","volume":"743","author":"T Kuroki","year":"1996","unstructured":"Kuroki T, Ichikawa J, Dai J, Meltzer HY (1996). R(+)-8-OH-DPAT, a 5-HT1A receptor agonist, inhibits amphetamine-induced serotonin and dopamine release in rat medial prefrontal cortex. Brain Res 743: 357\u2013361.","journal-title":"Brain Res"},{"key":"BF1300610_CR42","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1016\/0091-3057(79)90040-6","volume":"11","author":"WH Lyness","year":"1979","unstructured":"Lyness WH, Friedle NM, Moore KE (1979). Destruction of dopaminergic nerve terminals in nucleus accumbens: effects on d-amphetamine self-administration. Pharmacol Biochem Behav 11: 553\u2013556.","journal-title":"Pharmacol Biochem Behav"},{"key":"BF1300610_CR43","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1016\/0091-3057(93)90547-7","volume":"46","author":"LD McCullough","year":"1993","unstructured":"McCullough LD, Cousins MS, Salamone JD (1993). The role of nucleus accumbens dopamine in responding on a continuous reinforcement operant schedule: a neurochemical and behavioral study. Pharmacol Biochem Behav 46: 581\u2013586.","journal-title":"Pharmacol Biochem Behav"},{"key":"BF1300610_CR44","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/0301-0082(80)90018-0","volume":"14","author":"GJ Mogenson","year":"1980","unstructured":"Mogenson GJ, Jones DL, Yim CY (1980). From motivation to action: functional interface between the limbic system and the motor system. Prog Neurobiol 14: 69\u201397.","journal-title":"Prog Neurobiol"},{"key":"BF1300610_CR45","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1002\/syn.10083","volume":"45","author":"CP Muller","year":"2002","unstructured":"Muller CP, Carey RJ, De Souza Silva MA, Jocham G, Huston JP (2002a). Cocaine increases serotonergic activity in the hippocampus and nucleus accumbens in vivo: 5-HT1A-receptor antagonism blocks behavioral but potentiates serotonergic activation. Synapse 45: 67\u201377.","journal-title":"Synapse"},{"key":"BF1300610_CR46","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/S0166-4328(02)00042-6","volume":"134","author":"CP Muller","year":"2002","unstructured":"Muller CP, De Souza Silva MA, DePalma G, Tomaz C, Carey RJ, Huston JP (2002b). The selective serotonin(1A)-receptor antagonist WAY 100635 blocks behavioral stimulating effects of cocaine but not ventral striatal dopamine increase. Behav Brain Res 134: 337\u2013346.","journal-title":"Behav Brain Res"},{"key":"BF1300610_CR47","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/S0166-4328(01)00421-1","volume":"130","author":"M Papa","year":"2002","unstructured":"Papa M, Diewald L, Carey MP, Esposito FJ, Carnevale UAG, Sadile AG (2002). A rostro-caudal dissociation in the dorsal and ventral striatum of the juvenile SHR suggests an anterior hypo- and a posterior hyperfunctioning mesocorticolimbic system. Behav Brain Res 130: 171\u2013179.","journal-title":"Behav Brain Res"},{"key":"BF1300610_CR48","doi-asserted-by":"publisher","first-page":"1607","DOI":"10.1097\/00001756-199705060-00011","volume":"8","author":"M Papa","year":"1997","unstructured":"Papa M, Sergeant JA, Sadile AG (1997). Differential expression of transcription factors in the accumbens of an animal model of ADHD. NeuroReport 8: 1607\u20131612.","journal-title":"NeuroReport"},{"key":"BF1300610_CR49","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/S0166-4328(97)00179-4","volume":"94","author":"M Papa","year":"1998","unstructured":"Papa M, Sergeant JA, Sadile AG (1998). Reduced transduction mechanisms in the anterior accumbal interface of an animal model of attention-deficit hyperactivity disorder. Behav Brain Res 94: 187\u2013195.","journal-title":"Behav Brain Res"},{"key":"BF1300610_CR50","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/S0166-4328(02)00291-7","volume":"137","author":"JA Parkinson","year":"2002","unstructured":"Parkinson JA, Dalley JW, Cardinal RN, Bamford A, Fehnert B, Lachenal G et al (2002). Nucleus accumbens dopamine depletion impairs both acquisition and performance of appetitive Pavlovian approach behaviour: implications for mesoaccumbens dopamine function. Behav Brain Res 137: 149\u2013163.","journal-title":"Behav Brain Res"},{"key":"BF1300610_CR51","doi-asserted-by":"crossref","first-page":"256","DOI":"10.3758\/BF03332119","volume":"27","author":"JA Parkinson","year":"1999","unstructured":"Parkinson JA, Robbins TW, Everitt BJ (1999). Selective excitotoxic lesions of the nucleus accumbens core and shell differentially affect aversive Pavlovian conditioning to discrete and contextual cues. Psychobiology 27: 256\u2013266.","journal-title":"Psychobiology"},{"key":"BF1300610_CR52","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/0014-2999(76)90299-5","volume":"35","author":"AJ Pijnenburg","year":"1976","unstructured":"Pijnenburg AJ, Honig WM, van der Jeyden JA, Van Rossum JM (1976). Effects of chemical stimulation of the mesolimbic dopamine system upon locomotor activity. Eur J Pharmacol 35: 45\u201358.","journal-title":"Eur J Pharmacol"},{"key":"BF1300610_CR53","first-page":"83","volume":"271","author":"S Prisco","year":"1994","unstructured":"Prisco S, Paganonne S, Esposito E (1994). Serotonin\u2013dopamine interaction in the rat ventral tegmental areas: an electrophysiological study in vivo. J Pharmacol Exp Ther 271: 83\u201390.","journal-title":"J Pharmacol Exp Ther"},{"key":"BF1300610_CR54","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1097\/00008877-199712000-00004","volume":"8","author":"E Przegalinski","year":"1997","unstructured":"Przegalinski E, Filip M (1997). Stimulation of serotonin (5-HT)1A receptors attenuates the locomotor, but not the discriminative, effects of amphetamine and cocaine in rats. Behav Pharmacol 8: 699\u2013706.","journal-title":"Behav Pharmacol"},{"key":"BF1300610_CR55","volume-title":"Abstract Viewer\/Itinerary Planner","author":"JB Richards","year":"2002","unstructured":"Richards JB, Ishiwari K, Hauskneckt K, Salamone JD (2002). Effects of nucleus accumbens dopamine depletion on the value of delayed rewards in rats. In: Abstract Viewer\/Itinerary Planner. On-line: Society for Neuroscience: Washington, DC."},{"key":"BF1300610_CR56","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1038\/285409a0","volume":"285","author":"TW Robbins","year":"1980","unstructured":"Robbins TW, Koob GF (1980). Selective disruption of displacement behaviour by lesions of the mesolimbic dopamine system. Nature 285: 409\u2013412.","journal-title":"Nature"},{"key":"BF1300610_CR57","first-page":"662","volume":"224","author":"TW Robbins","year":"1983","unstructured":"Robbins TW, Roberts DC, Koob G (1983). Effects of d-amphetamine and apomorphine upon operant behavior and schedule-induced licking in rats with 6-hydroxydopamine-induced lesions of the nucleus accumbens. J Pharmacol Exp Ther 224: 662\u2013673.","journal-title":"J Pharmacol Exp Ther"},{"key":"BF1300610_CR58","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1124\/jpet.102.035063","volume":"305","author":"JD Salamone","year":"2003","unstructured":"Salamone JD, Correa M, Mingote S, Weber SM (2003). Nucleus accumbens dopamine and the regulation of effort in food-seeking behavior: implications for studies of natural motivation, psychiatry, and drug abuse. J Pharmacol Exp Ther 305: 1\u20138.","journal-title":"J Pharmacol Exp Ther"},{"key":"BF1300610_CR59","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/S0149-7634(96)00017-6","volume":"21","author":"JD Salamone","year":"1997","unstructured":"Salamone JD, Cousins MS, Snyder BJ (1997). Behavioral functions of nucleus accumbens dopamine: empirical and conceptual problems with the anhedonia hypothesis. Neurosci Biobehav Rev 21: 341\u2013359.","journal-title":"Neurosci Biobehav Rev"},{"key":"BF1300610_CR60","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/0091-3057(94)00294-S","volume":"50","author":"JD Salamone","year":"1995","unstructured":"Salamone JD, Kurth P, McCullough LD, Sokolowski JD (1995). The effects of nucleus accumbens dopamine depletions on continuously reinforced operant responding: contrasts with the effects of extinction. Pharmacol Biochem Behav 50: 437\u2013443.","journal-title":"Pharmacol Biochem Behav"},{"key":"BF1300610_CR61","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/0014-2999(88)90380-9","volume":"157","author":"CM Sinton","year":"1988","unstructured":"Sinton CM, Fallon SL (1988). Electrophysiological evidence for a functional differentiation between subtypes of the 5-HT1 receptor. Eur J Pharmacol 157: 173\u2013181.","journal-title":"Eur J Pharmacol"},{"key":"BF1300610_CR62","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1016\/S0091-3057(97)00544-3","volume":"59","author":"JD Sokolowski","year":"1998","unstructured":"Sokolowski JD, Salamone JD (1998). The role of nucleus accumbens dopamine in lever pressing and response allocation: effects of 6-OHDA injected into core and dorsomedial shell. Pharmacol Biochem Behav 59: 557\u2013566.","journal-title":"Pharmacol Biochem Behav"},{"key":"BF1300610_CR63","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/S0166-4328(97)00175-7","volume":"94","author":"MV Solanto","year":"1998","unstructured":"Solanto MV (1998). Neuropsychopharmacological mechanisms of stimulant drug action in attention-deficit hyperactivity disorder: a review and integration. Behav Brain Res 94: 127\u2013152.","journal-title":"Behav Brain Res"},{"key":"BF1300610_CR64","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/0006-8993(82)90685-0","volume":"253","author":"C Spyraki","year":"1982","unstructured":"Spyraki C, Fibiger HC, Phillips AG (1982). Dopaminergic substrates of amphetamine-induced place preference conditioning. Brain Res 253: 185\u2013193.","journal-title":"Brain Res"},{"key":"BF1300610_CR65","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1007\/s002130050859","volume":"142","author":"JR Taylor","year":"1999","unstructured":"Taylor JR, Horger BA (1999). Enhanced responding for conditioned reward produced by intra-accumbens amphetamine is potentiated after cocaine sensitisation. Psychopharmacology 142: 31\u201340.","journal-title":"Psychopharmacology"},{"key":"BF1300610_CR66","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1007\/BF00555222","volume":"84","author":"JR Taylor","year":"1984","unstructured":"Taylor JR, Robbins TW (1984). Enhanced behavioral control by conditioned reinforcers following microinjections of D-amphetamine into the nucleus accumbens. Psychopharmacology 84: 405\u2013412.","journal-title":"Psychopharmacology"},{"key":"BF1300610_CR67","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1007\/BF00179197","volume":"90","author":"JR Taylor","year":"1986","unstructured":"Taylor JR, Robbins TW (1986). 6-Hydroxydopamine lesions of the nucleus accumbens, but not of the caudate nucleus, attenuate enhanced responding with reward-related stimuli produced by intraaccumbens D-amphetamine. Psychopharmacology 90: 390\u2013397.","journal-title":"Psychopharmacology"},{"key":"BF1300610_CR68","volume-title":"Program No. 940.1 Society for Neuroscience Abstract Viewer\/Itinerary Planner","author":"DEH Theobald","year":"2004","unstructured":"Theobald DEH, Winstanley CA, Dalley JW, Robbins TW (2004). Performance of a task measuring impulsive choice alters monoamine function in rat frontal cortex. In: Program No. 940.1 Society for Neuroscience Abstract Viewer\/Itinerary Planner. On-line, Society for Neuroscience: Washington, DC."},{"key":"BF1300610_CR69","volume-title":"Program No. 757.6 Society for Neuroscience Abstract Viewer\/Itinerary Planner","author":"MM Van Gaalen","year":"2003","unstructured":"Van Gaalen MM, Van Koten RC, Schoffelmeer ANM, Vanderschuren LJM (2003). Dopaminergic involvement in cognitive impulsivity. In: Program No. 757.6 Society for Neuroscience Abstract Viewer\/Itinerary Planner. On-line, Society for Neuroscience: Washington, DC."},{"key":"BF1300610_CR70","doi-asserted-by":"publisher","first-page":"4718","DOI":"10.1523\/JNEUROSCI.5606-03.2004","volume":"24","author":"CA Winstanley","year":"2004","unstructured":"Winstanley CA, Theobald DE, Cardinal RN, Robbins TW (2004). Contrasting roles for basolateral amygdala and orbitofrontal cortex in impulsive choice. J Neurosci 24: 4718\u20134722.","journal-title":"J Neurosci"},{"key":"BF1300610_CR71","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1007\/s00213-003-1546-3","volume":"170","author":"CA Winstanley","year":"2003","unstructured":"Winstanley CA, Theobald DE, Dalley JW, Robbins TW (2003). Global 5-HT depletion attenuates the ability of amphetamine to decrease impulsive choice in rats. Psychopharmacology 170: 320\u2013331.","journal-title":"Psychopharmacology"},{"key":"BF1300610_CR72","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1038\/sj.npp.1300434","volume":"29","author":"CA Winstanley","year":"2004","unstructured":"Winstanley CA, Theobald DE, Dalley JW, Robbins TW (2004). Fractionating impulsivity: contrasting effects of central 5-HT depletion on different measures of impulsive behavior. Neuropsychopharmacology 29: 1331\u20131343 (originally published online 9 February 2004 at: http:\/\/www.acnp.org\/citations\/NPP02090403391\/default.pdf ).","journal-title":"Neuropsychopharmacology"}],"container-title":["Neuropsychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/1300610.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/1300610","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/1300610.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T02:47:43Z","timestamp":1684205263000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1300610"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1,26]]},"references-count":72,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,4]]}},"alternative-id":["BF1300610"],"URL":"https:\/\/doi.org\/10.1038\/sj.npp.1300610","relation":{},"ISSN":["0893-133X","1740-634X"],"issn-type":[{"value":"0893-133X","type":"print"},{"value":"1740-634X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,1,26]]}}}