{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T03:38:37Z","timestamp":1784864317179,"version":"3.55.0"},"reference-count":67,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2005,2,9]],"date-time":"2005-02-09T00:00:00Z","timestamp":1107907200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropsychopharmacol"],"published-print":{"date-parts":[[2005,6]]},"DOI":"10.1038\/sj.npp.1300688","type":"journal-article","created":{"date-parts":[[2005,2,9]],"date-time":"2005-02-09T16:46:52Z","timestamp":1107967612000},"page":"1193-1203","source":"Crossref","is-referenced-by-count":119,"title":["GABRA2 Alleles Moderate the Subjective Effects of Alcohol, Which are Attenuated by Finasteride"],"prefix":"10.1038","volume":"30","author":[{"given":"Amira","family":"Pierucci-Lagha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Covault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Feinn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maggie","family":"Nellissery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Hernandez-Avila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryl","family":"Oncken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A Leslie","family":"Morrow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry R","family":"Kranzler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2005,2,9]]},"reference":[{"key":"BF1300688_CR1","unstructured":"American Psychiatric Association (1994). Diagnostic and Statistical Manual of Mental Disorders, 4th edn. American Psychiatric Press: Washington, DC."},{"key":"BF1300688_CR2","first-page":"449","volume":"25","author":"A Balakleevsky","year":"1990","unstructured":"Balakleevsky A, Colombo G, Fadda F, Gessa GL (1990). Ro19-4603, a benzodiazepine inverse agonist, attenuates voluntary ethanol consumption in rats selectively bred for high ethanol preference. Alcohol Alcohol 25: 449\u2013452.","journal-title":"Alcohol Alcohol"},{"key":"BF1300688_CR3","doi-asserted-by":"publisher","first-page":"R1","DOI":"10.1016\/S0014-2999(99)00678-0","volume":"384","author":"ML Barbaccia","year":"1999","unstructured":"Barbaccia ML, Affricano D, Trabucchi M, Purdy RH, Colombo G, Agabio R et al (1999). Ethanol markedly increases \u2018GABAergic\u2019 neurosteroids in alcohol-preferring rats. Eur J Pharmacol 384: R1\u2013R2.","journal-title":"Eur J Pharmacol"},{"key":"BF1300688_CR4","doi-asserted-by":"publisher","first-page":"577","DOI":"10.15288\/jsa.1993.54.577","volume":"54","author":"LO Bauer","year":"1993","unstructured":"Bauer LO, Hesselbrock VM (1993). EEG, autonomic and subjective correlates of the risk for alcoholism. J Stud Alcohol 54: 577\u2013589.","journal-title":"J Stud Alcohol"},{"key":"BF1300688_CR5","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/0091-3057(93)90338-T","volume":"46","author":"AE Boyle","year":"1993","unstructured":"Boyle AE, Segal R, Smith BR, Amit Z (1993). Bidirectional effects of GABAergic agonists and antagonists on maintenance of voluntary ethanol intake in rats. Pharmacol Biochem Behav 46: 179\u2013182.","journal-title":"Pharmacol Biochem Behav"},{"key":"BF1300688_CR6","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/S0741-8329(02)00199-4","volume":"26","author":"JA Chester","year":"2002","unstructured":"Chester JA, Cunningham CL (2002). GABA(A) receptor modulation of the rewarding and aversive effects of ethanol. Alcohol 26: 131\u2013143.","journal-title":"Alcohol"},{"key":"BF1300688_CR7","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/0376-8716(94)90163-5","volume":"34","author":"MA Chutuape","year":"1994","unstructured":"Chutuape MA, de Wit H (1994). Relationship between subjective effects and drug preferences: ethanol and diazepam. Drug Alcohol Depend 34: 243\u2013251.","journal-title":"Drug Alcohol Depend"},{"key":"BF1300688_CR8","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1002\/ajmg.b.30091","volume":"129B","author":"C Covault","year":"2004","unstructured":"Covault C, Gelernter J, Hesselbrock V, Nellissery M, Kranzler HR (2004). Allelic and haplotypic association of GABRA2 with alcohol dependence. Am J Med Genet 129B: 104\u2013109.","journal-title":"Am J Med Genet"},{"key":"BF1300688_CR9","first-page":"263","volume":"28","author":"M Davies","year":"2003","unstructured":"Davies M (2003). The role of GABAA receptors in mediating the effects of alcohol in the central nervous system. J Psychiatry Neurosci 28: 263\u2013274.","journal-title":"J Psychiatry Neurosci"},{"key":"BF1300688_CR10","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1111\/j.1530-0277.1987.tb01263.x","volume":"11","author":"H de Wit","year":"1987","unstructured":"de Wit H, Uhlenhuth EH, Johanson CE (1987). Individual differences in behavioral and subjective responses to alcohol. Alcohol Clin Exp Res 11: 52\u201359.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300688_CR11","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1086\/383283","volume":"74","author":"HJ Edenberg","year":"2004","unstructured":"Edenberg HJ, Dick DM, Xuei X, Tian H, Almasy L, Bauer LO et al (2004). Variations in GABRA2, encoding the alpha 2 subunit of the GABAA receptor, are associated with alcohol dependence and with brain oscillations. Am J Hum Genet 74: 705\u2013714.","journal-title":"Am J Hum Genet"},{"key":"BF1300688_CR12","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1016\/j.neuroscience.2003.11.017","volume":"123","author":"DA Finn","year":"2004","unstructured":"Finn DA, Sinnott RS, Ford MM, Long SL, Tanchuck MA, Phillips TJ (2004). Sex differences in the effect of ethanol injection and consumption on brain allopregnanolone levels in C57BL\/6 mice. Neuroscience 123: 813\u2013819.","journal-title":"Neuroscience"},{"key":"BF1300688_CR13","volume-title":"Structured Clinical Interview for DSM-IV Axis I Disorders\u2014Patient Edition (SCID\u2014I\/P, Version 2.0)","author":"MB First","year":"1995","unstructured":"First MB, Spitzer RL, Gibbon M, Williams JBW (1995). Structured Clinical Interview for DSM-IV Axis I Disorders\u2014Patient Edition (SCID\u2014I\/P, Version 2.0). Biometrics Research Department, New York State Psychiatric Institute: New York."},{"key":"BF1300688_CR14","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1007\/s002130050685","volume":"139","author":"AC Grobin","year":"1998","unstructured":"Grobin AC, Matthews DB, Devaud LL, Morrow AL (1998). The role of GABA(A) receptors in the acute and chronic effects of ethanol. Psychopharmacology (Berl) 139: 2\u201319.","journal-title":"Psychopharmacology (Berl)"},{"key":"BF1300688_CR15","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/S0376-8716(98)00073-8","volume":"51","author":"RA Harris","year":"1998","unstructured":"Harris RA, Mihic SJ, Valenzuela CF (1998). Alcohol and benzodiazepines: recent mechanistic studies. Drug Alcohol Depend 51: 155\u2013164.","journal-title":"Drug Alcohol Depend"},{"key":"BF1300688_CR16","doi-asserted-by":"publisher","first-page":"262","DOI":"10.15288\/jsa.1992.53.262","volume":"53","author":"AC Heath","year":"1992","unstructured":"Heath AC, Martin NG (1992). Genetic differences in psychomotor performance decrement after alcohol: a multivariate analysis. J Stud Alcohol 53: 262\u2013271.","journal-title":"J Stud Alcohol"},{"key":"BF1300688_CR17","doi-asserted-by":"publisher","first-page":"1903","DOI":"10.1111\/j.1530-0277.1998.tb05897.x","volume":"22","author":"L Holdstock","year":"1998","unstructured":"Holdstock L, de Wit H (1998). Individual differences in the biphasic effects of ethanol. Alcohol Clin Exp Res 22: 1903\u20131911.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300688_CR18","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1111\/j.1530-0277.2000.tb02057.x","volume":"24","author":"L Holdstock","year":"2000","unstructured":"Holdstock L, King AC, de Wit H (2000). Subjective and objective responses to ethanol in moderate\/heavy and light social drinkers. Alcohol Clin Exp Res 24: 789\u2013794.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300688_CR19","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/S0006-8993(03)02978-0","volume":"980","author":"RT Khisti","year":"2003","unstructured":"Khisti RT, VanDoren MJ, O'Buckley T, Morrow AL (2003). Neuroactive steroid 3 alpha-hydroxy-5 alpha-pregnan-20-one modulates ethanol-induced loss of righting reflex in rats. Brain Res 980: 255\u2013265.","journal-title":"Brain Res"},{"key":"BF1300688_CR20","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1124\/mol.56.5.1087","volume":"56","author":"VV Koltchine","year":"1999","unstructured":"Koltchine VV, Finn SE, Jenkins A, Nikolaeva N, Lin A, Harrison NL (1999). Agonist gating and isoflurane potentiation in the human gamma-aminobutyric acid type A receptor determined by the volume of a second transmembrane domain residue. Mol Pharmacol 56: 1087\u20131093.","journal-title":"Mol Pharmacol"},{"key":"BF1300688_CR21","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1002\/(SICI)1096-8628(19980508)81:3<216::AID-AJMG2>3.0.CO;2-U","volume":"81","author":"JC Long","year":"1998","unstructured":"Long JC, Knowler WC, Hanson RL, Robin RW, Urbanek M, Moore E et al (1998). Evidence for genetic linkage to alcohol dependence on chromosomes 4 and 11 from an autosome-wide scan in an Am Evidence for genetic linkage to alcohol dependence on chromosomes 4 and 11 from an autosome-wide scan in an American Indian population. Am J Med Genet 81: 216\u2013221.","journal-title":"Am J Med Genet"},{"key":"BF1300688_CR22","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1126\/science.290.5489.131","volume":"290","author":"K Low","year":"2000","unstructured":"Low K, Crestani F, Keist R, Benke D, Brunig I, Benson JA et al (2000). Molecular and neuronal substrate for the selective attenuation of anxiety. Science 290: 131\u2013134.","journal-title":"Science"},{"key":"BF1300688_CR23","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/0005-7967(80)90067-4","volume":"18","author":"SA Maisto","year":"1980","unstructured":"Maisto SA, Connors GJ, Tucker JA, McCollam JB (1980). Validation of the sensation scale, a measure of subjective physiological responses to alcohol. Behav Res Ther 18: 37\u201343.","journal-title":"Behav Res Ther"},{"key":"BF1300688_CR24","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1111\/j.1530-0277.1993.tb00739.x","volume":"17","author":"CS Martin","year":"1993","unstructured":"Martin CS, Earleywire M, Musty RE, Perrine MW, Swift RM (1993). Development and validation of the Biphasic Alcohol Effects Scale. Alcohol Clin Exp Res 17: 140\u2013146.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300688_CR25","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1080\/09595238880000041","volume":"7","author":"NG Martin","year":"1988","unstructured":"Martin NG (1988). Twin studies of alcohol consumption, metabolism and sensitivity. Aust Drug Alcohol Rev 7: 9\u201312.","journal-title":"Aust Drug Alcohol Rev"},{"key":"BF1300688_CR26","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1007\/BF01070893","volume":"15","author":"NG Martin","year":"1985","unstructured":"Martin NG, Oakeshott JG, Gibson JB, Starmer GA, Perl J, Wilks AV (1985). A twin study of psychomotor and physiological responses to an acute dose of alcohol. Behav Genet 15: 305\u2013347.","journal-title":"Behav Genet"},{"key":"BF1300688_CR27","doi-asserted-by":"publisher","first-page":"9305","DOI":"10.1073\/pnas.160128797","volume":"97","author":"MP Mascia","year":"2000","unstructured":"Mascia MP, Trudell JR, Harris RA (2000). Specific binding sites for alcohols and anesthetics on ligand-gated ion channels. Proc Natl Acad Sci USA 97: 9305\u20139310.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF1300688_CR28","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1016\/0091-3057(88)90137-2","volume":"30","author":"WJ McBride","year":"1998","unstructured":"McBride WJ, Murphy JM, Lumeng Land Li TK (1998). Effects of Ro15-4513, fluoxetine and desipramine on intake of ethanol water and food in alcohol preferring and non-preferring lines of rats. Pharmacol Biochem Behav 30: 1045\u20131050.","journal-title":"Pharmacol Biochem Behav"},{"key":"BF1300688_CR29","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1038\/38738","volume":"389","author":"SJ Mihic","year":"1997","unstructured":"Mihic SJ, Ye Q, Wick MJ, Koltchine VV, Krasowski MD, Finn SE et al (1997). Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors. Nature 389: 385\u2013389.","journal-title":"Nature"},{"key":"BF1300688_CR30","doi-asserted-by":"publisher","first-page":"1933","DOI":"10.1111\/j.1530-0277.1999.tb04094.x","volume":"23","author":"AL Morrow","year":"1999","unstructured":"Morrow AL, Janis GC, VanDoren MJ, Matthews DB, Samson HH, Jan PH et al (1999). Neurosteroids mediate pharmacological effects of ethanol: a new mechanism of action? Alcohol Clin Exp Res 23: 1933\u20131940.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300688_CR31","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/S0165-0173(01)00127-8","volume":"37","author":"AL Morrow","year":"2001","unstructured":"Morrow AL, VanDoren MJ, Penland SN, Matthews DB (2001). The role of GABAergic neuroactive steroids in ethanol action, tolerance and dependence. Brain Res Brain Res Rev 37: 98\u2013109.","journal-title":"Brain Res Brain Res Rev"},{"key":"BF1300688_CR32","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1111\/j.1530-0277.1989.tb00322.x","volume":"13","author":"HB Moss","year":"1989","unstructured":"Moss HB, Yao JK, Maddock JM (1989). Responses by sons of alcoholic fathers to alcoholic and placebo drinks: perceived mood, intoxication, and plasma prolactin. Alcohol Clin Exp Res 13: 252\u2013257.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300688_CR33","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1037\/0033-2909.108.3.383","volume":"108","author":"DB Newlin","year":"1990","unstructured":"Newlin DB, Thompson JB (1990). Alcohol challenge with sons of alcoholics: a critical review analysis. Psychol Bull 108: 383\u2013402.","journal-title":"Psychol Bull"},{"key":"BF1300688_CR34","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/BF03189869","volume":"16","author":"M Ohtawa","year":"1991","unstructured":"Ohtawa M, Morikawa H, Shimazaki J (1991). Pharmacokinetic and biochemical efficacy after a single and multiple oral administration of N-(2methyl-2propyl)-3-oxo-4-aza-5-\u03b1-androst-1-ene-17-carboxamide, a new type of specific competitive inhibitor of testosterone 5-\u03b1-reductase, in volunteers. Eur J Drug Metab Pharmacokinet 16: 15\u201321.","journal-title":"Eur J Drug Metab Pharmacokinet"},{"key":"BF1300688_CR35","doi-asserted-by":"publisher","first-page":"289","DOI":"10.15288\/jsa.1985.46.289","volume":"46","author":"SS O'Malley","year":"1985","unstructured":"O'Malley SS, Maisto SA (1985). Effects of family drinking history and expectancies on responses to alcohol in men. J Stud Alcohol 46: 289\u2013297.","journal-title":"J Stud Alcohol"},{"key":"BF1300688_CR36","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1037\/1064-1297.5.3.183","volume":"5","author":"NM Petry","year":"1997","unstructured":"Petry NM (1997). Benzodiazepine\u2013GABA modulation of concurrent ethanol and sucrose reinforcement in the rat. Exp Clin Psychopharmacol 5: 183\u2013194.","journal-title":"Exp Clin Psychopharmacol"},{"key":"BF1300688_CR37","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/0163-7258(88)90109-X","volume":"36","author":"LA Pohorecky","year":"1988","unstructured":"Pohorecky LA, Brick J (1988). Pharmacology of ethanol. Pharmacol Ther 36: 335\u2013427.","journal-title":"Pharmacol Ther"},{"key":"BF1300688_CR38","doi-asserted-by":"publisher","first-page":"2171","DOI":"10.1210\/endo.139.4.5866","volume":"139","author":"A Poletti","year":"1998","unstructured":"Poletti A, Negri-Cesi P, Rabuffetti M, Colciago A, Celotti F, Martini L (1998). Transient expression of the 5-reductase type 2 isozyme in the rat brain in late fetal and early postnatal life. Endocrinology 139: 2171\u20132178.","journal-title":"Endocrinology"},{"key":"BF1300688_CR39","doi-asserted-by":"publisher","first-page":"1534","DOI":"10.1176\/ajp.149.11.1534","volume":"149","author":"VE Pollock","year":"1992","unstructured":"Pollock VE (1992). Meta-analysis of subjective sensitivity to alcohol in sons of alcoholics. Am J Psychiatry 149: 1534\u20131538.","journal-title":"Am J Psychiatry"},{"key":"BF1300688_CR40","doi-asserted-by":"publisher","first-page":"297","DOI":"10.15288\/jsa.1986.47.297","volume":"47","author":"VE Pollock","year":"1986","unstructured":"Pollock VE, Teasdale TW, Gabrielli WF, Knop J (1986). Subjective and objective measures of response to alcohol among young men at risk for alcoholism. J Stud Alcohol 47: 297\u2013304.","journal-title":"J Stud Alcohol"},{"key":"BF1300688_CR41","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1111\/j.1530-0277.1993.tb00736.x","volume":"17","author":"S Rassnick","year":"1993","unstructured":"Rassnick S, D'Amico E, Riley E, Koob GF (1993). GABA antagonist and benzodiazepine partial inverse agonist reduce motivated responding for ethanol. Alcohol Clin Exp Res 17: 124\u2013130.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300688_CR42","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1002\/(SICI)1096-8628(19980508)81:3<207::AID-AJMG1>3.0.CO;2-T","volume":"8","author":"T Reich","year":"1998","unstructured":"Reich T, Edenberg HJ, Goate A, Williams JT, Rice JP, Van Eerdewegh P et al (1998). Genome-wide search for genes affecting the risk for alcohol dependence. Am J Med Genet 8: 207\u2013215.","journal-title":"Am J Med Genet"},{"key":"BF1300688_CR43","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1097\/00002826-199619040-00011","volume":"19","author":"E Romeo","year":"1996","unstructured":"Romeo E, Brancati A, De Lorenzo A, Fucci P, Furnari C, Pompili E et al (1996). Marked decrease of plasma neuroactive steroids during alcohol withdrawal. Clin Neuropharmacol 19: 366\u2013369.","journal-title":"Clin Neuropharmacol"},{"key":"BF1300688_CR44","doi-asserted-by":"publisher","first-page":"101","DOI":"10.3109\/15622970009150572","volume":"1","author":"E Romeo","year":"2000","unstructured":"Romeo E, Pompili E, di Michele F, Pace M, Rupprecht R, Bernardi G et al (2000). Effects of fluoxetine, indomethacine and placebo on 3 alpha, 5 alpha tetrahydroprogesterone (THP) plasma levels in uncomplicated alcohol withdrawal. World J Biol Psychiatry 1: 101\u2013104.","journal-title":"World J Biol Psychiatry"},{"key":"BF1300688_CR45","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1038\/44579","volume":"401","author":"U Rudolph","year":"1999","unstructured":"Rudolph U, Crestani F, Benke D, Brunig I, Benson JA, Fritschy JM et al (1999). Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes. Nature 401: 796\u2013800.","journal-title":"Nature"},{"key":"BF1300688_CR46","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1016\/0091-3057(87)90357-1","volume":"27","author":"HH Samson","year":"1987","unstructured":"Samson HH, Tolliver GA, Pfeffer AU, Sadeghi KG, Mills FG (1987). Oral ethanol reinforcement in the rat: effect of the partial inverse benzodiazepine agonist Ro15-4513. Pharmacol Biochem Behav 27: 517\u2013519.","journal-title":"Pharmacol Biochem Behav"},{"key":"BF1300688_CR47","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1111\/j.1530-0277.2003.tb04405.x","volume":"27","author":"T Sarkola","year":"2003","unstructured":"Sarkola T, Eriksson CJ (2003). Testosterone increases in men after a low dose of alcohol. Alcohol Clin Exp Res 27: 682\u2013685.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300688_CR48","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1093\/alcalc\/35.1.84","volume":"35","author":"T Sarkola","year":"2000","unstructured":"Sarkola T, Fukunaga T, Makisalo H, Peter Eriksson CJ (2000). Acute effect of alcohol on androgens in premenopausal women. Alcohol Alcohol 35: 84\u201390.","journal-title":"Alcohol Alcohol"},{"key":"BF1300688_CR49","doi-asserted-by":"publisher","first-page":"430","DOI":"10.15288\/jsa.1988.49.430","volume":"49","author":"TM Savoie","year":"1988","unstructured":"Savoie TM, Emory EK, Moody-Thomas S (1988). Acute alcohol intoxication in socially drinking female and male offspring of alcoholic fathers. J Stud Alcohol 49: 430\u2013435.","journal-title":"J Stud Alcohol"},{"key":"BF1300688_CR50","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1001\/archpsyc.1984.01790200061008","volume":"41","author":"MA Schuckit","year":"1984","unstructured":"Schuckit MA (1984). Subjective responses to alcohol in sons of alcoholics and control subjects. Arch Gen Psychiatry 41: 879\u2013884.","journal-title":"Arch Gen Psychiatry"},{"key":"BF1300688_CR51","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1176\/ajp.151.2.184","volume":"151","author":"MA Schuckit","year":"1994","unstructured":"Schuckit MA (1994). Low level of response to alcohol as a predictor of future alcoholism. Am J Psychiatry 151: 184\u2013189.","journal-title":"Am J Psychiatry"},{"key":"BF1300688_CR52","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1093\/alcalc\/35.3.242","volume":"35","author":"MA Schuckit","year":"2000","unstructured":"Schuckit MA, Smith TL, Kalmijn J, Tsuang J, Hesselbrock V, Bucholz K (2000). Response to alcohol in daughters of alcoholics: a pilot study and a comparison with sons of alcoholics. Alcohol Alcohol 35: 242\u2013248.","journal-title":"Alcohol Alcohol"},{"key":"BF1300688_CR53","doi-asserted-by":"publisher","first-page":"368","DOI":"10.15288\/jsa.1996.57.368","volume":"57","author":"MA Schuckit","year":"1996","unstructured":"Schuckit MA, Tsuang JW, Anthenelli RM, Tipp JE, Nurnberger Jr JI (1996). Alcohol challenges in young men from alcoholic pedigrees and control families: a report from the COGA project. J Stud Alcohol 57: 368\u2013377.","journal-title":"J Stud Alcohol"},{"key":"BF1300688_CR54","first-page":"227","volume":"27","author":"BR Smith","year":"1992","unstructured":"Smith BR, Robidoux J, Amit Z (1992). GABAergic involvement in the acquisition of voluntary ethanol intake in laboratory rats. Alcohol Alcohol 27: 227\u2013231.","journal-title":"Alcohol Alcohol"},{"key":"BF1300688_CR55","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1007\/978-1-4612-0357-5_3","volume-title":"Measuring Alcohol Consumption","author":"LC Sobell","year":"1992","unstructured":"Sobell LC, Sobell MD (1992). Timeline follow-back: a technique for assessing self-reported alcohol consumption. In: Litten R, Allen J (eds). Measuring Alcohol Consumption. Human Press: Clifton, NJ. pp 41\u201365."},{"key":"BF1300688_CR56","first-page":"3636","volume":"83","author":"B Stoffel-Wagner","year":"1998","unstructured":"Stoffel-Wagner B, Watzka M, Steckelbroeck S, Wickert L, Schramm J, Romalo G et al (1998). Expression of 5-reductase in the human temporal lobe of children and adults. J Clin Endocrinol Metab 83: 3636\u20133642.","journal-title":"J Clin Endocrinol Metab"},{"key":"BF1300688_CR57","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.1176\/ajp.151.10.1463","volume":"151","author":"RM Swift","year":"1994","unstructured":"Swift RM, Whelihan W, Kuznetsov O, Buongiorno G, Hsuing H (1994). Naltrexone-induced alterations in human ethanol intoxication. Am J Psychiatry 151: 1463\u20131467.","journal-title":"Am J Psychiatry"},{"key":"BF1300688_CR58","doi-asserted-by":"publisher","first-page":"2599","DOI":"10.1046\/j.1460-9568.2003.02988.x","volume":"18","author":"M Tauber","year":"2003","unstructured":"Tauber M, Calame-Droz E, Prut L, Rudolph U, Crestani F (2003). Alpha2-gamma-aminobutyric acid (GABA)A receptors are the molecular substrates mediating precipitation of narcosis but not of sedation by the combined use of diazepam and alcohol in vivo. Eur J Neurosci 18: 2599\u20132604.","journal-title":"Eur J Neurosci"},{"key":"BF1300688_CR59","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1021\/js950100g","volume":"85","author":"G Tian","year":"1996","unstructured":"Tian G (1996). In vivo time-dependent inhibition of human steroid 5 alpha-reductase by finasteride. J Pharm Sci 85: 106\u2013111.","journal-title":"J Pharm Sci"},{"key":"BF1300688_CR60","doi-asserted-by":"publisher","first-page":"2291","DOI":"10.1021\/bi00174a041","volume":"33","author":"G Tian","year":"1994","unstructured":"Tian G, Stuart JD, Moss ML, Domanico PL, Bramson HN, Patel IR et al (1994). 17 beta-(N-tert-butylcarbamoyl)-4-aza-5 alpha-androstan-1-en-3-one is an active site-directed slow time-dependent inhibitor of human steroid 5 alpha-reductase 1. Biochemistry 33: 2291\u20132296.","journal-title":"Biochemistry"},{"key":"BF1300688_CR61","doi-asserted-by":"publisher","first-page":"6464","DOI":"10.1073\/pnas.111055398","volume":"98","author":"I Tobler","year":"2001","unstructured":"Tobler I, Kopp C, Deboer T, Rudolph U (2001). Diazepam-induced changes in sleep: role of the alpha 1 GABA(A) receptor subtype. Proc Natl Acad Sci USA 98: 6464\u20136469.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF1300688_CR62","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.1038\/sj.npp.1300170","volume":"28","author":"JM Torres","year":"2003","unstructured":"Torres JM, Ortega E (2003). Alcohol intoxication increases allopregnanolone levels in female adolescent humans. Neuropsychopharmacology 28: 1207\u20131209.","journal-title":"Neuropsychopharmacology"},{"key":"BF1300688_CR63","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1007\/s00213-003-1662-0","volume":"172","author":"JM Torres","year":"2004","unstructured":"Torres JM, Ortega E (2004). Alcohol intoxication increases allopregnanolone levels in male adolescent humans. Psychopharmacology (Berl) 172: 352\u2013355.","journal-title":"Psychopharmacology (Berl)"},{"key":"BF1300688_CR64","doi-asserted-by":"publisher","first-page":"76S","DOI":"10.1111\/j.1530-0277.2001.tb02378.x","volume":"25","author":"S Ueno","year":"2001","unstructured":"Ueno S, Harris RA, Messing RO, Sanchez-Perez AM, Hodge CW, McMahon T et al (2001). Alcohol actions on GABA(A) receptors: from protein structure to mouse behavior. Alcohol Clin Exp Res 25: 76S\u201381S.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300688_CR65","doi-asserted-by":"publisher","first-page":"1982","DOI":"10.1523\/JNEUROSCI.20-05-01982.2000","volume":"20","author":"MJ VanDoren","year":"2000","unstructured":"VanDoren MJ, Matthews DB, Janis GC, Grobin AC, Devaud LL, Morrow AL (2000). Neuroactive steroid 3-alpha-hydroxy-5-alpha-pregnan-20-one modulates electrophysiological and behavioral actions of ethanol. J Neurosci 20: 1982\u20131989.","journal-title":"J Neurosci"},{"key":"BF1300688_CR66","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1097\/01.ALC.0000067974.41160.95","volume":"27","author":"RJ Viken","year":"2003","unstructured":"Viken RJ, Rose RJ, Morzorati SL, Christian JC, Li TK (2003). Subjective intoxication in response to alcohol challenge: heritability and covariation with personality, breath alcohol level, and drinking history. Alcohol Clin Exp Res 27: 795\u2013803.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300688_CR67","first-page":"41","volume-title":"Human Metabolism of Alcohol","author":"PE Watson","year":"1989","unstructured":"Watson PE (1989). Total body water and blood alcohol levels: updating the fundamentals. In: Crow KE, Batt RD (eds). Human Metabolism of Alcohol. CRC Press: Boca Raton, FL. pp 41\u201356."}],"container-title":["Neuropsychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/1300688.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/1300688","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/1300688.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T06:48:18Z","timestamp":1684219698000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1300688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2,9]]},"references-count":67,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,6]]}},"alternative-id":["BF1300688"],"URL":"https:\/\/doi.org\/10.1038\/sj.npp.1300688","relation":{},"ISSN":["0893-133X","1740-634X"],"issn-type":[{"value":"0893-133X","type":"print"},{"value":"1740-634X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,2,9]]}}}