{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T18:32:38Z","timestamp":1762540358533},"reference-count":57,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2005,4,6]],"date-time":"2005-04-06T00:00:00Z","timestamp":1112745600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropsychopharmacol"],"published-print":{"date-parts":[[2005,7]]},"DOI":"10.1038\/sj.npp.1300723","type":"journal-article","created":{"date-parts":[[2005,4,6]],"date-time":"2005-04-06T15:00:39Z","timestamp":1112799639000},"page":"1392-1399","source":"Crossref","is-referenced-by-count":23,"title":["Cortical NAA Deficits in HIV Infection without Dementia: Influence of Alcoholism Comorbidity"],"prefix":"10.1038","volume":"30","author":[{"given":"Adolf","family":"Pfefferbaum","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elfar","family":"Adalsteinsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edith V","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2005,4,6]]},"reference":[{"key":"BF1300723_CR1","first-page":"1941","volume":"24","author":"E Adalsteinsson","year":"2003","unstructured":"Adalsteinsson E, Langer-Gould A, Homer RJ, Rao A, Sullivan EV, Pfefferbaum A et al (2003). Gray matter NAA deficits in secondary progressive but not relapse remitting multiple sclerosis: quantification with volumetric MR spectroscopic imaging. Am J Neuroradiol 24: 1941\u20131945.","journal-title":"Am J Neuroradiol"},{"key":"BF1300723_CR2","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1002\/(SICI)1522-2594(199908)42:2<314::AID-MRM14>3.0.CO;2-X","volume":"42","author":"E Adalsteinsson","year":"1999","unstructured":"Adalsteinsson E, StarLack J, Meyer C, Spielman D (1999). Reduced spatial side lobes in chemical-shift imaging. Magn Reson Med 42: 314\u2013323.","journal-title":"Magn Reson Med"},{"key":"BF1300723_CR3","unstructured":"American Psychiatric Association (1994). Diagnostic and Statistical Manual of Mental Disorder (DSM-IV). American Psychiatric Association: Washington."},{"key":"BF1300723_CR4","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1097\/01.ALC.0000057947.57330.BE","volume":"27","author":"GJ Bagby","year":"2003","unstructured":"Bagby GJ, Stoltz DA, Zhang P, Kolls JK, Brown J, Bohm Jr RP et al (2003). The effect of chronic binge ethanol consumption on the primary stage of SIV infection in rhesus macaques. Alcohol Clin Exp Res 27: 495\u2013502.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300723_CR5","first-page":"7","volume-title":"Clinical MR Neuroimaging: Diffusion, Perfusion and Spectroscopy","author":"PB Barker","year":"2005","unstructured":"Barker PB (2005). Fundamentals of MR spectroscopy. In: Gillard J, Waldman A, Barker P (eds). Clinical MR Neuroimaging: Diffusion, Perfusion and Spectroscopy. Cambridge University Press: Cambridge. pp 7\u201326."},{"key":"BF1300723_CR6","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1148\/radiology.195.1.7892496","volume":"195","author":"PB Barker","year":"1995","unstructured":"Barker PB, Lee RR, McArthur JC (1995). AIDS dementia complex: evaluation with proton MR spectroscopic imaging. Radiology 195: 58\u201364.","journal-title":"Radiology"},{"key":"BF1300723_CR7","first-page":"141","volume":"12","author":"ER Cerwonka","year":"2000","unstructured":"Cerwonka ER, Isbell TR, Hansen CE (2000). Psychosocial factors as predictors of unsafe sexual practices among young adults. AIDS Educ Prev 12: 141\u2013153.","journal-title":"AIDS Educ Prev"},{"key":"BF1300723_CR8","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1212\/WNL.53.4.782","volume":"53","author":"L Chang","year":"1999","unstructured":"Chang L, Ernst T, Leonido-Yee M, Witt M, Speck O, Walot I et al (1999). Highly active antiretroviral therapy reverses brain metabolite abnormalities in mild HIV dementia. Neurology 53: 782\u2013789.","journal-title":"Neurology"},{"key":"BF1300723_CR9","doi-asserted-by":"publisher","first-page":"1638","DOI":"10.1006\/nimg.2002.1254","volume":"17","author":"L Chang","year":"2002","unstructured":"Chang L, Ernst T, Witt MD, Ames N, Gaiefsky M, Miller E (2002). Relationships among brain metabolites, cognitive function, and viral loads in antiretroviral-naive HIV patients. Neuroimage 17: 1638\u20131648.","journal-title":"Neuroimage"},{"key":"BF1300723_CR10","doi-asserted-by":"publisher","first-page":"1336","DOI":"10.1016\/j.neuroimage.2004.07.067","volume":"23","author":"L Chang","year":"2004","unstructured":"Chang L, Lee PL, Yiannoutsos CT, Ernst T, Marra CM, Richards T et al (2004). A multicenter in vivo proton-MRS study of HIV-associated dementia and its relationship to age. Neuroimage 23: 1336\u20131347.","journal-title":"Neuroimage"},{"key":"BF1300723_CR11","first-page":"27","volume-title":"Clinical MR Neuroimaging: Diffusion, Perfusion and Spectroscopy","author":"T Ernst","year":"2005","unstructured":"Ernst T (2005). Quantification and analysis in MR spectroscopy. In: Gillard J, Waldman A, Barker P (eds). Clinical MR Neuroimaging: Diffusion, Perfusion and Spectroscopy. Cambridge University Press: Cambridge. pp 27\u201337."},{"issue":"Suppl 1","key":"BF1300723_CR12","doi-asserted-by":"publisher","first-page":"S61","DOI":"10.1097\/00002030-200401001-00009","volume":"18","author":"T Ernst","year":"2004","unstructured":"Ernst T, Chang L (2004). Effect of aging on brain metabolism in antiretroviral-naive HIV patients. AIDS 18 (Suppl 1): S61\u2013S67.","journal-title":"AIDS"},{"key":"BF1300723_CR13","first-page":"531","volume":"152","author":"G Fein","year":"1990","unstructured":"Fein G, Bachman L, Fisher S, Davenport L (1990). Cognitive impairments in abstinent alcoholics. West J Med 152: 531\u2013537.","journal-title":"West J Med"},{"key":"BF1300723_CR14","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/0006-3223(94)00119-N","volume":"37","author":"G Fein","year":"1995","unstructured":"Fein G, Biggins CA, MacKay S (1995). Alcohol abuse and HIV infection have additive effects on frontal cortex function as measured by auditory evoked potential P3a latency. Biol Psychiatry 37: 183\u2013195.","journal-title":"Biol Psychiatry"},{"key":"BF1300723_CR15","doi-asserted-by":"publisher","first-page":"196S","DOI":"10.1111\/j.1530-0277.1998.tb04000.x","volume":"22","author":"G Fein","year":"1998","unstructured":"Fein G, Fletcher DJ, Di Sclafani V (1998). Effect of chronic alcohol abuse on the CNS morbidity of HIV disease. Alcohol Clin Exp Res 22: 196S\u2013200S.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300723_CR16","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/1471-2202-5-10","volume":"5","author":"RA Fuller","year":"2004","unstructured":"Fuller RA, Westmoreland SV, Ratai E, Greco JB, Kim JP, Lentz MR et al (2004). A prospective longitudinal in vivo 1H MR spectroscopy study of the SIV\/macaque model of neuroAIDS. BMC Neurosci 5: 10.","journal-title":"BMC Neurosci"},{"key":"BF1300723_CR17","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1176\/appi.ajp.161.2.249","volume":"161","author":"JE Green","year":"2004","unstructured":"Green JE, Saveanu RV, Bornstein RA (2004). The effect of previous alcohol abuse on cognitive function in HIV infection. Am J Psychiatry 161: 249\u2013254.","journal-title":"Am J Psychiatry"},{"key":"BF1300723_CR18","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1136\/jnnp.65.3.301","volume":"65","author":"MJ Harrison","year":"1998","unstructured":"Harrison MJ, Newman SP, Hall-Craggs MA, Fowler CJ, Miller R, Kendall BE et al (1998). Evidence of CNS impairment in HIV infection: clinical, neuropsychological, EEG, and MRI\/MRS study. J Neurol Neurosurg Psychiatry 65: 301\u2013307.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"BF1300723_CR19","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1017\/S1355617700000230","volume":"1","author":"RK Heaton","year":"1995","unstructured":"Heaton RK, Grant I, Butters N, White DA, Kirson D, Atkinson JH et al (1995). The HNRC 500\u2014neuropsychology of HIV infection at different disease stages. HIV Neurobehavioral Research Center. J Int Neuropsychol Soc 1: 231\u2013251.","journal-title":"J Int Neuropsychol Soc"},{"key":"BF1300723_CR20","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1002\/mrm.20007","volume":"51","author":"R Hurd","year":"2004","unstructured":"Hurd R, Sailasuta N, Srinivasan R, Vigneron DB, Pelletier D, Nelson SJ (2004). Measurement of brain glutamate using TE-averaged PRESS at 3T. Magn Reson Med 51: 435\u2013440.","journal-title":"Magn Reson Med"},{"key":"BF1300723_CR21","first-page":"191","volume-title":"Evaluation of Chemotherapeutic Agents","author":"DA Karnofsky","year":"1949","unstructured":"Karnofsky DA (1949). The clinical evaluation of chemotherapeutic agents in cancer. In: MacLeod CM (ed). Evaluation of Chemotherapeutic Agents. Columbia University Press: New York. pp 191\u2013205."},{"key":"BF1300723_CR22","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1002\/mrm.10267","volume":"48","author":"DH Kim","year":"2002","unstructured":"Kim DH, Adalsteinsson E, Glover GH, Spielman DM (2002). Regularized higher-order in vivo shimming. Magn Reson Med 48: 715\u2013722.","journal-title":"Magn Reson Med"},{"key":"BF1300723_CR23","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1002\/jmri.10295","volume":"17","author":"PL Lee","year":"2003","unstructured":"Lee PL, Yiannoutsos CT, Ernst T, Chang L, Marra CM, Jarvik JG et al (2003). A multi-center 1H MRS study of the AIDS dementia complex: validation and preliminary analysis. J Magn Reson Imaging 17: 625\u2013633.","journal-title":"J Magn Reson Imaging"},{"key":"BF1300723_CR24","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1007\/BF02599920","volume":"10","author":"F Lefevre","year":"1995","unstructured":"Lefevre F, O'Leary B, Moran M, Mossar M, Yarnold PR, Martin GJ et al (1995). Alcohol consumption among HIV-infected patients. J Gen Intern Med 10: 458\u2013460.","journal-title":"J Gen Intern Med"},{"key":"BF1300723_CR25","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1016\/S0730-725X(03)00181-4","volume":"21","author":"BS Li","year":"2003","unstructured":"Li BS, Wang H, Gonen O (2003). Metabolite ratios to assumed stable creatine level may confound the quantification of proton brain MR spectroscopy. Magn Reson Imaging 21: 923\u2013928.","journal-title":"Magn Reson Imaging"},{"key":"BF1300723_CR26","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1097\/00004728-198907000-00006","volume":"13","author":"KO Lim","year":"1989","unstructured":"Lim KO, Pfefferbaum A (1989). Segmentation of MR brain images into cerebrospinal fluid spaces, white and gray matter. J Comput Assist Tomogr 13: 588\u2013593.","journal-title":"J Comput Assist Tomogr"},{"key":"BF1300723_CR27","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1111\/j.1530-0277.2001.tb02383.x","volume":"25","author":"K Mann","year":"2001","unstructured":"Mann K, Agartz I, Harper C, Shoaf S, Rawlings R, Momenan R et al (2001). Neuroimaging in alcoholism: ethanol and brain damage. Alcohol Clin Exp Res (Suppl) 25: 104\u2013109S.","journal-title":"Alcohol Clin Exp Res (Suppl)"},{"key":"BF1300723_CR28","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1111\/j.1530-0277.1995.tb00992.x","volume":"19","author":"PR Martin","year":"1995","unstructured":"Martin PR, Gibbs SJ, Nimmerrichter AA, Riddle WR, Welch LW, Willcott MR (1995). Brain proton magnetic resonance spectroscopy studies in recently abstinent alcoholics. Alcohol Clin Exp Res 19: 1078\u20131082.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300723_CR29","unstructured":"Mayer D, Kim D-H, Adalsteinsson E, Spielman DM (2004). Fast CT-PRESS based spiral CSI at 3T. Paper presented at: 12th Annual Meeting of the ISMRM (Kyoto, Japan).."},{"key":"BF1300723_CR30","first-page":"288","volume":"25","author":"DJ Meyerhoff","year":"2001","unstructured":"Meyerhoff DJ (2001). Effects of alcohol and HIV infection on the central nervous system. Alcohol Res Health 25: 288\u2013298.","journal-title":"Alcohol Res Health"},{"key":"BF1300723_CR31","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1212\/WNL.43.3_Part_1.509","volume":"43","author":"DJ Meyerhoff","year":"1993","unstructured":"Meyerhoff DJ, Mackay S, Bachman L, Poole N, Dillon WP, Weiner MW et al (1993). Reduced brain N-acetylaspartate suggests neuronal loss in cognitively impaired human immunodeficiency virus seropositive individuals\u2014in vivo H-1 magnetic resonance spectroscopic imaging. Neurology 43: 509\u2013515.","journal-title":"Neurology"},{"key":"BF1300723_CR32","first-page":"973","volume":"17","author":"DJ Meyerhoff","year":"1996","unstructured":"Meyerhoff DJ, Weiner MW, Fein G (1996). Deep gray matter structures in HIV infection: a proton MR spectroscopic study. Am J Neuroradiol 17: 973\u2013978.","journal-title":"Am J Neuroradiol"},{"key":"BF1300723_CR33","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1080\/1355621031000069855","volume":"8","author":"MJ Miguez","year":"2003","unstructured":"Miguez MJ, Shor-Posner G, Morales G, Rodriguez A, Burbano X (2003). HIV treatment in drug abusers: impact of alcohol use. Addict Biol 8: 33\u201337.","journal-title":"Addict Biol"},{"key":"BF1300723_CR34","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1002\/(SICI)1522-2586(199901)9:1<10::AID-JMRI2>3.0.CO;2-W","volume":"9","author":"HE Moller","year":"1999","unstructured":"Moller HE, Vermathen P, Lentschig MG, Schuierer G, Schwarz S, Wiedermann D et al (1999a). Metabolic characterization of AIDS dementia complex by spectroscopic imaging. J Magn Reson Imaging 9: 10\u201318.","journal-title":"J Magn Reson Imaging"},{"key":"BF1300723_CR35","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1002\/(SICI)1522-2586(199901)9:1<10::AID-JMRI2>3.0.CO;2-W","volume":"9","author":"HE Moller","year":"1999","unstructured":"Moller HE, Vermathen P, Lentschig MG, Schuierer G, Schwarz S, Wiedermann D et al (1999b). Metabolic characterization of AIDS dementia complex by spectroscopic imaging. J Magn Reson Imaging 9: 10\u201318.","journal-title":"J Magn Reson Imaging"},{"key":"BF1300723_CR36","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/S0925-4927(02)00088-4","volume":"116","author":"TE Nordahl","year":"2002","unstructured":"Nordahl TE, Salo R, Possin K, Gibson R, Flynn NM, Leamon M et al (2002). Low N-acetyl-aspartate and high choline in the anterior cingulum of recently abstinent methamphetamine dependent subjects: a proton MRS study. Psychiatry Res 116: 43\u201352.","journal-title":"Psychiatry Res"},{"key":"BF1300723_CR37","doi-asserted-by":"publisher","first-page":"1673","DOI":"10.1111\/j.1530-0277.2001.tb02174.x","volume":"25","author":"J O'Neill","year":"2001","unstructured":"O'Neill J, Cardenas VA, Meyerhoff DJ (2001a). Effects of abstinence on the brain: quantitative magnetic resonance imaging and magnetic resonance spectroscopic imaging in chronic alcohol abuse. Alcohol Clin Exp Res 25: 1673\u20131682.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300723_CR38","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1080\/13556210020077073","volume":"6","author":"J O'Neill","year":"2001","unstructured":"O'Neill J, Cardenas VA, Meyerhoff DJ (2001b). Separate and interactive effects of cocaine and alcohol dependence on brain structures and metabolites: quantitative MRI and proton MR spectroscopic imaging. Addict Biol 6: 347\u2013361.","journal-title":"Addict Biol"},{"key":"BF1300723_CR39","first-page":"437","volume-title":"Review of NIAAA's Neuroscience and Behavioral Research Portfolio","author":"M Oscar-Berman","year":"2000","unstructured":"Oscar-Berman M (2000). Neuropsychological vulnerabilities in chronic alcoholism. In: Noronha A, Eckardt M, Warren K (eds). Review of NIAAA's Neuroscience and Behavioral Research Portfolio, NIAAA Research Monograph No. 34, National Institutes of Health: Bethesda, MD. pp 437\u2013472."},{"key":"BF1300723_CR40","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1109\/TSMC.1979.4310076","volume":"9","author":"N Otsu","year":"1979","unstructured":"Otsu N (1979). A threshold selection method from gray-level histograms. IEEE Trans Syst Man Cybernet 9: 63\u201366.","journal-title":"IEEE Trans Syst Man Cybernet"},{"key":"BF1300723_CR41","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1001\/archpsyc.56.2.185","volume":"56","author":"A Pfefferbaum","year":"1999","unstructured":"Pfefferbaum A, Adalsteinsson E, Spielman D, Sullivan EV, Lim KO (1999a). In vivo brain concentrations of N-acetyl compounds, creatine and choline in Alzheimer's disease. Arch Gen Psychiatry 56: 185\u2013192.","journal-title":"Arch Gen Psychiatry"},{"key":"BF1300723_CR42","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1002\/(SICI)1522-2594(199902)41:2<276::AID-MRM10>3.0.CO;2-8","volume":"41","author":"A Pfefferbaum","year":"1999","unstructured":"Pfefferbaum A, Adalsteinsson E, Spielman D, Sullivan EV, Lim KO (1999b). In vivo spectroscopic quantification of the N-acetyl moiety, creatine and choline from large volumes of gray and white matter: effects of normal aging. Magn Reson Med 41: 276\u2013284.","journal-title":"Magn Reson Med"},{"key":"BF1300723_CR43","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1111\/j.1530-0277.2002.tb02638.x","volume":"26","author":"A Pfefferbaum","year":"2002","unstructured":"Pfefferbaum A, Rosenbloom M, Sullivan E (2002). Alcoholism and AIDS: MR imaging approaches for detecting interaction neuropathology. Alcohol Clin Exp Res 26: 1031\u20131046.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300723_CR44","first-page":"191","volume":"10","author":"B Ross","year":"1994","unstructured":"Ross B, Michaelis T (1994). Clinical applications of magnetic resonance spectroscopy. Magn Reson Q 10: 191\u2013247.","journal-title":"Magn Reson Q"},{"key":"BF1300723_CR45","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1097\/01.ALC.0000122103.74491.78","volume":"28","author":"JH Samet","year":"2004","unstructured":"Samet JH, Horton NJ, Meli S, Freedberg KA, Palepu A (2004). Alcohol consumption and antiretroviral adherence among HIV-infected persons with alcohol problems. Alcohol Clin Exp Res 28: 572\u2013577.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300723_CR46","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1111\/j.1530-0277.1999.tb04038.x","volume":"23","author":"D Seitz","year":"1999","unstructured":"Seitz D, Widmann U, Seeger U, Nagele T, Klose U, Mann K et al (1999). Localized proton magnetic resonance spectroscopy of the cerebellum in detoxifying alcoholics. Alcohol Clin Exp Res 23: 158\u2013163.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300723_CR47","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1002\/hbm.10062","volume":"17","author":"S Smith","year":"2002","unstructured":"Smith S (2002). Fast robust automated brain extraction. Hum Brain Mapp 17: 143\u2013155.","journal-title":"Hum Brain Mapp"},{"key":"BF1300723_CR48","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1002\/mrm.1910350313","volume":"35","author":"BJ Soher","year":"1996","unstructured":"Soher BJ, van Zijl PCM, Duyn JH, Barker PB (1996). Quantitative proton MR spectroscopic imaging of the human brain. Magn Reson Med 35: 356\u2013363.","journal-title":"Magn Reson Med"},{"key":"BF1300723_CR49","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1002\/mrm.1910190107","volume":"19","author":"D Spielman","year":"1991","unstructured":"Spielman D, Pauly J, Macovski A, Enzmann D (1991). Spectroscopic imaging with multi-dimensional pulses for excitation: SIMPLE. Magn Reson Med 19: 67\u201384.","journal-title":"Magn Reson Med"},{"key":"BF1300723_CR50","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1001\/archneur.1996.00550020052015","volume":"53","author":"RA Stern","year":"1996","unstructured":"Stern RA, Silva SG, Chaisson N, Evans DL (1996). Influence of cognitive reserve on neuropsychological functioning in asymptomatic human immunodeficiency virus-1 infection. Arch Neurol 53: 148\u2013153.","journal-title":"Arch Neurol"},{"key":"BF1300723_CR51","first-page":"473","volume-title":"Review of NIAAA's Neuroscience and Behavioral Research Portfolio","author":"EV Sullivan","year":"2000","unstructured":"Sullivan EV (2000). Human brain vulnerability to alcoholism: evidence from neuroimaging studies. In: Noronha A, Eckardt M, Warren K (eds). Review of NIAAA's Neuroscience and Behavioral Research Portfolio, NIAAA Research Monograph No. 34 National Institutes of Health: Bethesda, MD. pp 473\u2013508."},{"key":"BF1300723_CR52","doi-asserted-by":"publisher","first-page":"1409","DOI":"10.1097\/01.ALC.0000085586.91726.46","volume":"27","author":"EV Sullivan","year":"2003","unstructured":"Sullivan EV (2003). Compromised pontocerebellar and cerebellothalamocortical systems: speculations on their contributions to cognitive and motor impairment in nonamnesic alcoholism. Alcohol Clin Exp Res 27: 1409\u20131419.","journal-title":"Alcohol Clin Exp Res"},{"key":"BF1300723_CR53","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1212\/WNL.46.3.783","volume":"46","author":"I Tracey","year":"1996","unstructured":"Tracey I, Carr CA, Guimaraes AR, Worth JL, Navia BA, Gonzalez RG (1996). Brain choline-containing compounds are elevated in HIV-positive patients before the onset of AIDS dementia complex: a proton magnetic resonance spectroscopic study. Neurology 46: 783\u2013788.","journal-title":"Neurology"},{"key":"BF1300723_CR54","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1007\/BF02033352","volume":"241","author":"J Viondury","year":"1994","unstructured":"Viondury J, Meyerhoff DJ, Cozzone PJ, Weiner MW (1994). What might be the impact on neurology of the analysis of brain metabolism by in vivo magnetic resonance spectroscopy? J Neurol 241: 354\u2013371.","journal-title":"J Neurol"},{"key":"BF1300723_CR55","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.1001\/archneur.58.8.1281","volume":"58","author":"HJ von Giesen","year":"2001","unstructured":"von Giesen HJ, Wittsack HJ, Wenserski F, Koller H, Hefter H, Arendt G (2001). Basal ganglia metabolite abnormalities in minor motor disorders associated with human immunodeficiency virus type 1. Arch Neurol 58: 1281\u20131286.","journal-title":"Arch Neurol"},{"key":"BF1300723_CR56","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/0741-8329(94)00090-5","volume":"12","author":"Y Wang","year":"1995","unstructured":"Wang Y, Watson RR (1995). Is alcohol consumption a cofactor in the development of acquired immunodeficiency syndrome? Alcohol 12: 105\u2013109.","journal-title":"Alcohol"},{"key":"BF1300723_CR57","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1016\/j.neuroimage.2004.07.033","volume":"23","author":"CT Yiannoutsos","year":"2004","unstructured":"Yiannoutsos CT, Ernst T, Chang L, Lee PL, Richards T, Marra CM et al (2004). Regional patterns of brain metabolites in AIDS dementia complex. Neuroimage 23: 928\u2013935.","journal-title":"Neuroimage"}],"container-title":["Neuropsychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/1300723.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/1300723","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/1300723.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T06:48:33Z","timestamp":1684219713000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1300723"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,4,6]]},"references-count":57,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2005,7]]}},"alternative-id":["BF1300723"],"URL":"https:\/\/doi.org\/10.1038\/sj.npp.1300723","relation":{},"ISSN":["0893-133X","1740-634X"],"issn-type":[{"value":"0893-133X","type":"print"},{"value":"1740-634X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,4,6]]}}}