{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T05:49:22Z","timestamp":1790920162661,"version":"4.1.0"},"reference-count":56,"publisher":"Springer Science and Business Media LLC","issue":"48","license":[{"start":{"date-parts":[[2001,10,25]],"date-time":"2001-10-25T00:00:00Z","timestamp":1003968000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2001,10,25]],"date-time":"2001-10-25T00:00:00Z","timestamp":1003968000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Oncogene"],"published-print":{"date-parts":[[2001,10,25]]},"DOI":"10.1038\/sj.onc.1204897","type":"journal-article","created":{"date-parts":[[2002,9,20]],"date-time":"2002-09-20T18:55:35Z","timestamp":1032548135000},"page":"7051-7063","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":169,"title":["Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties"],"prefix":"10.1038","volume":"20","author":[{"given":"Eric Y","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malavi T","family":"Madireddi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul V","family":"Gopalkrishnan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Leszczyniecka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zao-zhong","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina V","family":"Lebedeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-chul","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongping","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiao Jiao","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Alexandre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinming","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicollaq","family":"Vozhilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei Xin","family":"Mei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith A","family":"Christiansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Sivo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil I","family":"Goldstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abner B","family":"Mhashilkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Chada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliezer","family":"Huberman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sidney","family":"Pestka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul B","family":"Fisher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2001,11,1]]},"reference":[{"key":"BF1204897_CR1","doi-asserted-by":"crossref","unstructured":"Alitalo R . 1990 Leuk. Res. 14: 501\u2013514","DOI":"10.1016\/0145-2126(90)90002-Q"},{"key":"BF1204897_CR2","doi-asserted-by":"crossref","unstructured":"Armstrong BK, Kricker A . 1994 Cancer Surv. 19\/20: 219\u2013240","DOI":"10.5840\/pdp19942011"},{"key":"BF1204897_CR3","doi-asserted-by":"crossref","unstructured":"Bishop JM . 1991 Cell 64: 235\u2013248","DOI":"10.1016\/0092-8674(91)90636-D"},{"key":"BF1204897_CR4","doi-asserted-by":"crossref","unstructured":"Blumberg H, Conklin D, Xu W, Grossmann A, Brender T, Carollo S, Eagan M, Foster D, Haldeman B, Hammond A, Haughen H, Jelinek L, Kelly J, Madden K, Maurer M, Parrish-Novak J, Prunkard D, Sexson S, Sprecher C, Waggie K, West J, Whitmore T, Yao L, Kuechle M, Dale B, Chandrasekher Y . 2001 Cell 104: 9\u201319","DOI":"10.1016\/S0092-8674(01)00187-8"},{"key":"BF1204897_CR5","doi-asserted-by":"crossref","unstructured":"Breathnach R, Benoist C, O'Hare K, Gannon F, Chambon P . 1978 Proc. Natl. Acad. Sci. USA 75: 4853\u20134857","DOI":"10.1073\/pnas.75.10.4853"},{"key":"BF1204897_CR6","doi-asserted-by":"crossref","unstructured":"Breathnach R, Chambon P . 1981 Annu. Rev. Biochem. 50: 349\u2013383","DOI":"10.1146\/annurev.bi.50.070181.002025"},{"key":"BF1204897_CR7","doi-asserted-by":"crossref","unstructured":"Chaiken IM, Williams WV . 1996 Trends Biotechnol. 14: 369\u2013375","DOI":"10.1016\/0167-7799(96)10050-0"},{"key":"BF1204897_CR8","doi-asserted-by":"crossref","unstructured":"Chu X, Newman J, Park B, Nares S, Ordonez G, Iacopino AM . 1999 Cell Tissue Res. 296: 331\u2013337","DOI":"10.1007\/s004410051293"},{"key":"BF1204897_CR9","doi-asserted-by":"crossref","unstructured":"Clark W . 1991 Br. J. Cancer 64: 631\u2013644","DOI":"10.1038\/bjc.1991.375"},{"key":"BF1204897_CR10","unstructured":"DeRisi J, Penland L, Brown PO, Bittner ML, Meltzer PS, Ray M, Chen Y, Su YA, Trent JM . 1996 Nat. Genet. 14: 457\u2013460"},{"key":"BF1204897_CR11","unstructured":"Falck-Pedersen E, Heinflink M, Alvira M, Nussenzveig DR, Gershengorn MC . 1994 Mol. Pharmacol. 45: 684\u2013689"},{"key":"BF1204897_CR12","unstructured":"Fisher PB . 1984 Tumor Promotion and Cocarcinogenesis In Vitro, Mechanisms of Tumor Promotion. Slaga TJ (ed) CRC Press Inc.: Boca Raton, Florida pp. 57\u201383"},{"key":"BF1204897_CR13","doi-asserted-by":"crossref","unstructured":"Fisher PB, Prignoli DR, Hermo Jr H, Weinstein IB, Pestka S . 1985 J. Interferon Res. 5: 11\u201322","DOI":"10.1089\/jir.1985.5.11"},{"key":"BF1204897_CR14","doi-asserted-by":"crossref","unstructured":"Gallagher G, Dickensheets H, Eskdale J, Izotova LS, Mirochnitchenko OV, Peat JD, Vasquez N, Pestka S, Donnelly RP, Kotenko SV . 2000 Genes Immun. 1: 442\u2013450","DOI":"10.1038\/sj.gene.6363714"},{"key":"BF1204897_CR15","doi-asserted-by":"crossref","unstructured":"Graham FL, Smiley J, Russell WC, Nairn R . 1977 J. Gen. Virol. 36: 59\u201372","DOI":"10.1099\/0022-1317-36-1-59"},{"key":"BF1204897_CR16","doi-asserted-by":"crossref","unstructured":"Graham GM, Guarini L, Moulton TA, Datta S, Ferrone S, Giacomini P, Kerbel RS, Fisher PB . 1991 Cancer Immunol. Immunotherap. 32: 382\u2013390","DOI":"10.1007\/BF01741333"},{"key":"BF1204897_CR17","doi-asserted-by":"crossref","unstructured":"Guarini L, Temponi M, Bruce JN, Bollon AP, Duigou GJ, Moulton TA, Ferrone S, Fisher PB . 1990 Intl. J. Cancer 46: 1041\u20131047","DOI":"10.1002\/ijc.2910460616"},{"key":"BF1204897_CR18","doi-asserted-by":"crossref","unstructured":"Herlyn M, Berking C, Li G, Satyamoorthy K . 2000 Melanoma Res. 10: 303\u2013312","DOI":"10.1097\/00008390-200008000-00001"},{"key":"BF1204897_CR19","doi-asserted-by":"crossref","unstructured":"Huang F, Adelman J, Jiang H, Goldstein NI, Fisher PB . 1999a Oncogene 18: 3546\u20133552","DOI":"10.1038\/sj.onc.1202715"},{"key":"BF1204897_CR20","doi-asserted-by":"crossref","unstructured":"Huang F, Adelman J, Jiang H, Goldstein NI, Fisher PB . 1999b Gene 236: 125\u2013131","DOI":"10.1016\/S0378-1119(99)00244-9"},{"key":"BF1204897_CR21","doi-asserted-by":"crossref","unstructured":"Jiang H, Fisher PB . 1993 Mol. Cell. Differ. 1: 285\u2013299","DOI":"10.1016\/0166-1280(93)87046-G"},{"key":"BF1204897_CR22","doi-asserted-by":"crossref","unstructured":"Jiang H, Kang D-C, Alexandre D, Fisher PB . 2000 Proc. Natl. Acad. Sci. USA 93: 9160\u20139165","DOI":"10.1073\/pnas.93.17.9160"},{"key":"BF1204897_CR23","unstructured":"Jiang H, Lin J, Fisher PB . 1994 Mol. Cell. Differ. 2: 221\u2013239"},{"key":"BF1204897_CR24","unstructured":"Jiang H, Lin JJ, Su Z-Z, Goldstein NI, Fisher PB . 1995b Oncogene 11: 2477\u20132486"},{"key":"BF1204897_CR25","unstructured":"Jiang H, Lin J, Su Z-Z, Kerbel RS, Herlyn M, Weissman RB, Welch D, Fisher PB . 1995a Oncogene 10: 1855\u20131864"},{"key":"BF1204897_CR26","unstructured":"Jiang H, Su Z-Z, Boyd J, Fisher PB . 1993 Mol. Cell. Differ. 1: 41\u201366"},{"key":"BF1204897_CR27","doi-asserted-by":"crossref","unstructured":"Jiang H, Su Z-Z, Lin JJ, Goldstein NI, Young CSH, Fisher PB . 1996 Proc. Natl. Acad. Sci. USA 93: 9160\u20139165","DOI":"10.1073\/pnas.93.17.9160"},{"key":"BF1204897_CR28","doi-asserted-by":"crossref","unstructured":"Kang D-C, Jiang H, Wu Q, Pestka S, Fisher PB . 2001 Gene 267: 233\u2013242","DOI":"10.1016\/S0378-1119(01)00384-5"},{"key":"BF1204897_CR29","doi-asserted-by":"crossref","unstructured":"Kang D-C, LaFrance R, Su Z-Z, Fisher PB . 1998 Proc. Natl. Acad. Sci. USA 95: 13788\u201313793","DOI":"10.1073\/pnas.95.23.13788"},{"key":"BF1204897_CR30","unstructured":"Kerbel RS, Man MS . 1984 Invasion Metastasis 4: Suppl 1 31\u201343"},{"key":"BF1204897_CR31","doi-asserted-by":"crossref","unstructured":"Kotenko SV, Izotova LS, Mirochnitchenko OV, Esterova E, Dickensheets H, Donnelly RP, Pestka S . 2001 J. Biol. Chem. 276: 2725\u20132732","DOI":"10.1074\/jbc.M007837200"},{"key":"BF1204897_CR32","unstructured":"Leszczyniecka M, Roberts T, Dent P, Grant S, Fisher PB . 2001 Pharmacol. Therapeut in press"},{"key":"BF1204897_CR33","doi-asserted-by":"crossref","unstructured":"Li DQ, Lee SB, Tseng SC . 1999 Curr. Eye Res. 19: 154\u2013161","DOI":"10.1076\/ceyr.19.2.154.5321"},{"key":"BF1204897_CR34","doi-asserted-by":"crossref","unstructured":"Madireddi MT, Dent P, Fisher PB . 2000a Oncogene 19: 1362\u20131368","DOI":"10.1038\/sj.onc.1203424"},{"key":"BF1204897_CR35","doi-asserted-by":"crossref","unstructured":"Madireddi MT, Dent P, Fisher PB . 2000b J. Cell. Physiol. 185: 36\u201346","DOI":"10.1002\/1097-4652(200010)185:1<36::AID-JCP3>3.0.CO;2-V"},{"key":"BF1204897_CR36","unstructured":"Madireddi MT, Su Z-Z, Young CSH, Goldstein NI, Fisher PB . 2000c Adv. Exptl. Med. Biol. 465: 239\u2013261"},{"key":"BF1204897_CR37","doi-asserted-by":"crossref","unstructured":"McGrory WJ, Bautista DS, Graham FL . 1988 Virology 163: 614\u2013617","DOI":"10.1016\/0042-6822(88)90302-9"},{"key":"BF1204897_CR38","doi-asserted-by":"crossref","unstructured":"Mhashilkar AB, Schrock RD, Hindi M, Liao J, Sieger K, Kourouma F, Zou-Yang XH, Onishi E, Takh O, Vedvick TS, Fanger G, Stewart L, Watson GJ, Snary D, Fisher PB, Saeki T, Roth JA, Ramesh R, Chada S . 2001 Mol. Med. 7: 271\u2013282","DOI":"10.1007\/BF03401847"},{"key":"BF1204897_CR39","doi-asserted-by":"crossref","unstructured":"Miller MS . 1999 J. Foot Ankle Surg. 38: 227\u2013231","DOI":"10.1016\/S1067-2516(99)80058-1"},{"key":"BF1204897_CR40","doi-asserted-by":"crossref","unstructured":"Ross DT, Scherf U, Eisen MB, Perou CM, Rees C, Spellman P, Iyer V, Jeffrey SS, Van de Rijn M, Waltham M, Pergamenschikov A, Lee JC, Lashkari D, Shalon D, Myers TG, Weinstein JN, Botstein D, Brown PO . 2000 Nat. Genet. 24: 227\u2013235","DOI":"10.1038\/73432"},{"key":"BF1204897_CR41","doi-asserted-by":"crossref","unstructured":"Saeki T, Mhashilkar A, Chada S, Branch C, Roth JA, Ramesh R . 2000 Gene Therapy 7: 2051\u20132057","DOI":"10.1038\/sj.gt.3301330"},{"key":"BF1204897_CR42","doi-asserted-by":"crossref","unstructured":"Saito I . 2000 Crit. Rev. Immunol. 20: 153\u2013165","DOI":"10.1615\/CritRevImmunol.v20.i2.40"},{"key":"BF1204897_CR43","unstructured":"Sambrook J, Fritsch EF, Maniatis T . 1989 Cold Spring Harbor Laboratory Press, 2nd ed Cold Spring Harbor, NY"},{"key":"BF1204897_CR44","doi-asserted-by":"crossref","unstructured":"Schena M, Shalon D, Heller R, Chai A, Brown PO, Davis RW . 1996 Proc. Natl. Acad. Sci. USA 93: 10614\u201310619","DOI":"10.1073\/pnas.93.20.10614"},{"key":"BF1204897_CR45","doi-asserted-by":"crossref","unstructured":"Soo C, Shaw WW, Freymiller E, Longaker MT, Bertolami CN, Chiu R, Tieu A, Ting K . 1999 J. Cell. Biochem. 74: 1\u201310","DOI":"10.1002\/(SICI)1097-4644(19990701)74:1<1::AID-JCB1>3.0.CO;2-M"},{"key":"BF1204897_CR46","doi-asserted-by":"crossref","unstructured":"Su Z-Z, Goldstein NI, Jiang H, Wang M-N, Duigou GJ, Young CSH, Fisher PB . 1999 Proc. Natl. Acad. Sci. USA 96: 15115\u201315120","DOI":"10.1073\/pnas.96.26.15115"},{"key":"BF1204897_CR47","doi-asserted-by":"crossref","unstructured":"Su Z-Z, Madireddi MT, Lin JJ, Young CSH, Kitada S, Reed JC, Goldstein NI, Fisher PB . 1998 Proc. Natl. Acad. Sci. USA 95: 14400\u201314405","DOI":"10.1073\/pnas.95.24.14400"},{"key":"BF1204897_CR48","doi-asserted-by":"crossref","unstructured":"Su Z-Z, Shi Y, Fisher PB . 1997 Proc. Natl. Acad. Sci. USA 94: 9125\u20139130","DOI":"10.1073\/pnas.94.17.9125"},{"key":"BF1204897_CR49","unstructured":"Su Z-Z, Yemul S, Estabrook A, Zimmer SG, Friedman RM, Fisher PB . 1995 Intl. J. Oncology 7: 1279\u20131284"},{"key":"BF1204897_CR50","unstructured":"Tonetti DA, Horio M, Collart FR, Huberman E . 1992 Cell Growth Differ. 3: 739\u2013745"},{"key":"BF1204897_CR51","unstructured":"Vita JR, Edwalds GM, Gorey T, Housepian EM, Fetell MR, Guarini L, Langer JA, Fisher PB . 1988 Anticancer Res. 8: 297\u2013302"},{"key":"BF1204897_CR52","doi-asserted-by":"crossref","unstructured":"Vogelstein B, Kinzler KW . 1991 Trends Genet. 9: 138\u2013141","DOI":"10.1016\/0168-9525(93)90209-Z"},{"key":"BF1204897_CR53","doi-asserted-by":"crossref","unstructured":"Volkert FC, Young CSH . 1983 Virology 125: 175\u2013193","DOI":"10.1016\/0042-6822(83)90072-7"},{"key":"BF1204897_CR54","first-page":"pp. 1","volume-title":"Differentiation Therapy.","author":"S Waxman","year":"1996","unstructured":"Waxman S . 1996 Differentiation Therapy. Waxman S (ed) Serono Symposium Publications, Rome, Italy pp. 1\u2013528"},{"key":"BF1204897_CR55","doi-asserted-by":"crossref","unstructured":"Xie MH, Aggarwal S, Ho WH, Foster J, Zhang Z, Stinson J, Wood WI, Goddard AD, Gurney AL . 2000 J. Biol. Chem. 275: 31335\u201331339","DOI":"10.1074\/jbc.M005304200"},{"key":"BF1204897_CR56","doi-asserted-by":"crossref","unstructured":"Zhang R, Tan Z, Liang P . 2000 J. Biol. Chem. 275: 24436\u201324443","DOI":"10.1074\/jbc.M001958200"}],"container-title":["Oncogene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/1204897.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1204897","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1204897.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T00:18:14Z","timestamp":1647908294000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1204897"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,10,25]]},"references-count":56,"journal-issue":{"issue":"48","published-print":{"date-parts":[[2001,10,25]]}},"alternative-id":["BF1204897"],"URL":"https:\/\/doi.org\/10.1038\/sj.onc.1204897","relation":{},"ISSN":["0950-9232","1476-5594"],"issn-type":[{"value":"0950-9232","type":"print"},{"value":"1476-5594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,10,25]]},"assertion":[{"value":"23 May 2001","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 August 2001","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 August 2001","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 November 2001","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}