{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T23:40:16Z","timestamp":1791157216504,"version":"4.1.0"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"19","license":[{"start":{"date-parts":[[2003,5,15]],"date-time":"2003-05-15T00:00:00Z","timestamp":1052956800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2003,5,15]],"date-time":"2003-05-15T00:00:00Z","timestamp":1052956800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Oncogene"],"published-print":{"date-parts":[[2003,5,15]]},"DOI":"10.1038\/sj.onc.1206474","type":"journal-article","created":{"date-parts":[[2003,5,27]],"date-time":"2003-05-27T13:28:34Z","timestamp":1054042114000},"page":"2972-2983","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":122,"title":["SASH1: a candidate tumor suppressor gene on chromosome 6q24.3 is downregulated in breast cancer"],"prefix":"10.1038","volume":"22","author":[{"given":"Constanze","family":"Zeller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"Hinzmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Seitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmuth","family":"Prokoph","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elke","family":"Burkhard-Goettges","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burkhard","family":"Jandrig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lope-Estevez","family":"Schwarz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Rosenthal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siegfried","family":"Scherneck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2003,5,15]]},"reference":[{"key":"BF1206474_CR1","doi-asserted-by":"crossref","unstructured":"Abdollahi A, Roberts D, Godwin AK, Schultz DC, Sonoda G, Testa JR and Hamilton TC . (1997). Oncogene, 14, 1973\u20131979.","DOI":"10.1038\/sj.onc.1201034"},{"key":"BF1206474_CR2","doi-asserted-by":"crossref","unstructured":"Acevedo CM, Henriquez M, Emmert-Buck MR and Chuaqui RF . (2002). Cancer, 94, 793\u2013802.","DOI":"10.1002\/cncr.10275"},{"key":"BF1206474_CR3","doi-asserted-by":"crossref","unstructured":"Barghorn A, Speel EJ, Farspour B, Saremaslani P, Schmid S, Perren A, Roth J, Heitz PU and Komminoth P . (2001). Am. J. Path., 158, 1903\u20131911.","DOI":"10.1016\/S0002-9440(10)64658-5"},{"key":"BF1206474_CR4","doi-asserted-by":"crossref","unstructured":"Beer S, Simins AB, Schuster A and Holzmann B . (2001). Biochim. Biophys. Acta, 1520, 89\u201393.","DOI":"10.1016\/S0167-4781(01)00242-1"},{"key":"BF1206474_CR5","doi-asserted-by":"crossref","unstructured":"Bilanges B, Varrault A, Basyuk E, Rodriguez C, Mazumdar A, Pantaloni C, Bockaert J, Theillet C, Spengler D and Journot L . (1999). Oncogene, 18, 3979\u20133988.","DOI":"10.1038\/sj.onc.1202933"},{"key":"BF1206474_CR6","doi-asserted-by":"crossref","unstructured":"Buday L . (1999). Biochim. Biophys. Acta, 1422, 187\u2013204.","DOI":"10.1016\/S0304-4157(99)00005-2"},{"key":"BF1206474_CR7","doi-asserted-by":"crossref","unstructured":"Carroll M, Tomasson MH, Barker GF, Golub TR and Gilliland DG . (1996). Proc. Natl. Acad Sci. USA, 93, 14845\u201314850.","DOI":"10.1073\/pnas.93.25.14845"},{"key":"BF1206474_CR8","doi-asserted-by":"crossref","unstructured":"Casey G . (1997). Curr. Opin. Oncol., 9, 88\u201393.","DOI":"10.1097\/00001622-199701000-00014"},{"key":"BF1206474_CR9","doi-asserted-by":"crossref","unstructured":"Cheng CW, Wu PE, Yu JC, Huang CS, Yue CT, Wu CW and Shen CY . (2001). Oncogene, 20, 3814\u20133823.","DOI":"10.1038\/sj.onc.1204505"},{"key":"BF1206474_CR10","doi-asserted-by":"crossref","unstructured":"Claudio JO, Zhu YX, Benn SJ, Shukla AH, McGlade CJ, Falcioni N and Stewart AK . (2001). Oncogene, 20, 5373\u20135377.","DOI":"10.1038\/sj.onc.1204698"},{"key":"BF1206474_CR11","doi-asserted-by":"crossref","unstructured":"De Jong MM, Nolte IM, Te Meerman GJ, Van der Graaf WTA, Oosterwijk JC, Kleibeuker JH, Schaapveld M and De Vries EGE . (2002). J. Med. Genet., 39, 225\u2013242.","DOI":"10.1136\/jmg.39.4.225"},{"key":"BF1206474_CR12","doi-asserted-by":"crossref","unstructured":"Devilee P and Cornelisse CJ . (1994). Biochim. Biophys. Acta., 1198, 113\u2013130.","DOI":"10.1016\/0304-419X(94)90009-4"},{"key":"BF1206474_CR13","doi-asserted-by":"crossref","unstructured":"Fujii H, Zhou W and Gabrielson E . (1996). Genes Chromosomes Cancer, 16, 35\u201339.","DOI":"10.1002\/(SICI)1098-2264(199605)16:1<35::AID-GCC5>3.0.CO;2-4"},{"key":"BF1206474_CR14","doi-asserted-by":"crossref","unstructured":"German Consortium for Hereditary Breast and Ovarian Cancer (2002). Int. J. Cancer, 97, 472\u2013480.","DOI":"10.1002\/ijc.1626"},{"key":"BF1206474_CR15","doi-asserted-by":"crossref","unstructured":"Goeze A, Schluns K, Wolf G, Thasler Z, Petersen S and Petersen I . (2002). J. Pathol., 196, 8\u201316.","DOI":"10.1002\/path.1009"},{"key":"BF1206474_CR16","doi-asserted-by":"crossref","unstructured":"Huang LW, Garrett AP, Muto MG, Colitti CV, Bell DA, Welch WR, Berkowitz RS and Mok SC . (2000). Hum. Pathol., 31, 367\u2013373.","DOI":"10.1016\/S0046-8177(00)80252-X"},{"key":"BF1206474_CR17","unstructured":"Kim CA, Gingery M, Pilpa RM and Bowie JU . (2002). Nature Struct. Biol., 9, 453\u2013457."},{"key":"BF1206474_CR18","doi-asserted-by":"crossref","unstructured":"Knudson AG . (1971). Proc. Natl. Acad. Sci. USA, 68, 820\u2013823.","DOI":"10.1073\/pnas.68.4.820"},{"key":"BF1206474_CR19","doi-asserted-by":"crossref","unstructured":"Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S, Liu Q, Cochran C, Bennett LM, Ding W, Bell R, Rosenthal J, Hussey C, Tran T, McClure M, Frye C, Hattier T, Phelps R, Haugen-Strano A, Katcher H, Yakumo K, Gholami Z, Shaffer D, Stone S, Bayer S, Wray C, Bodgen R, Dayananth P, Ward J, Tonin P, Narod S, Bristow P, Norris FH, Helvering L, Morrison P, Rosteck P, Lai M, Barret JC, Lewis C, Neuhausen S, Cannon-Albright L, Goldgar D, Wiseman R, Kamb A and Skolnick MH . (1994). Science, 266, 66\u201371.","DOI":"10.1126\/science.7545954"},{"key":"BF1206474_CR20","unstructured":"Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N and Ohara O . (1998). DNA Res, 5, 277\u2013286."},{"key":"BF1206474_CR21","unstructured":"Pagotto U, Arzberger T, Theodoropoulou M, Gr\u00fcbler Y, Pantaloni C, Saeger W, Losa M, Journot L, Stalla GK and Spengler D . (2000). Cancer Res., 60, 6794\u20136799."},{"key":"BF1206474_CR22","doi-asserted-by":"crossref","unstructured":"Pawson T . (1995). Nature, 373, 573\u2013580.","DOI":"10.1038\/373573a0"},{"key":"BF1206474_CR23","doi-asserted-by":"crossref","unstructured":"Rodriguez C, Causse A, Ursule E and Theillet C . (2000). Genes Chromosomes Cancer, 27, 76\u201384.","DOI":"10.1002\/(SICI)1098-2264(200001)27:1<76::AID-GCC10>3.0.CO;2-E"},{"key":"BF1206474_CR24","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-662-05747-6","volume-title":"Angewandte Statistik","author":"L Sachs","year":"1992","unstructured":"Sachs L . (1992). Angewandte Statistik. Springer Verlag: Berlin, Heidelberg, New York, Tokio."},{"key":"BF1206474_CR25","doi-asserted-by":"crossref","unstructured":"Schmitt AO, Specht T, Beckmann G, Dahl E, Pilarsky CP, Hinzmann B and Rosenthal A . (1999). Nucl. Acids Res., 27, 4251\u20134260.","DOI":"10.1093\/nar\/27.21.4251"},{"key":"BF1206474_CR26","doi-asserted-by":"crossref","unstructured":"Serra-Pages C, Kedersha NL, Fazikas L, Medley Q, Debant A and Streuli M . (1995). EMBO J., 14, 2827\u20132838.","DOI":"10.1002\/j.1460-2075.1995.tb07282.x"},{"key":"BF1206474_CR27","doi-asserted-by":"crossref","unstructured":"Shridhar V, Staub J, Huntley B, Cliby W, Jenkins R, Pass HI, Hartmann L and Smith DI . (1999). Oncogene, 18, 3913\u20133918.","DOI":"10.1038\/sj.onc.1202756"},{"key":"BF1206474_CR28","unstructured":"Spengler D, Villalba M, Hoffmann A, Pantaloni C, Houssami S, Bockaert J and Journot L . (1997). EMBO J., 16, 2814\u20132825."},{"key":"BF1206474_CR29","doi-asserted-by":"crossref","unstructured":"Srikantan V, Sesterhenn IA, Davis L, Hankins GR, Avallone FA, Livezey JR, Connelly R, Mostofi FK, McLeod DG, Moul JW, Chandrasekharappa SC and Srivastava S . (1999). Int. J. Cancer, 84, 331\u2013335.","DOI":"10.1002\/(SICI)1097-0215(19990621)84:3<331::AID-IJC23>3.0.CO;2-J"},{"key":"BF1206474_CR30","doi-asserted-by":"crossref","unstructured":"Stallmach I, Zenklusen P, Komminoth P, Schmid S, Perren A, Roos M, Jianming Z, Heitz PU and Pfaltz M . (2002). Virchows Arch., 440, 77\u201384.","DOI":"10.1007\/s004280100523"},{"key":"BF1206474_CR31","unstructured":"Theile M, Seitz S, Arnold W, Jandrig B, Frege R, Schlag PM, Haensch W, Guski H, Winzer KJ, Barrett JC and Scherneck S . (1996). Oncogene, 13, 677\u2013685."},{"key":"BF1206474_CR32","doi-asserted-by":"crossref","unstructured":"Tirkkonen M, Tanner M, Karhu R, Kallioniemi A, Isola J and Kallioniemi OP . (1998). Genes Chromosomes Cancer, 21, 177\u2013184.","DOI":"10.1002\/(SICI)1098-2264(199803)21:3<177::AID-GCC1>3.0.CO;2-X"},{"key":"BF1206474_CR33","doi-asserted-by":"crossref","unstructured":"Uchida T, Nakao A, Nakano N, Kurasamu A, Saito H, Okumura K and Ogawa H . (2001). Biochem. Biophys. Res. Commun., 288, 137\u2013141.","DOI":"10.1006\/bbrc.2001.5722"},{"key":"BF1206474_CR34","doi-asserted-by":"crossref","unstructured":"Virmani AK, Fong KM, Kodagoda D, Mclntire D, Hung J, Tonk V, Minna JD and Gazdar AF . (1998). Genes Chromosomes. Cancer, 21, 308\u2013319.","DOI":"10.1002\/(SICI)1098-2264(199804)21:4<308::AID-GCC4>3.0.CO;2-2"},{"key":"BF1206474_CR35","doi-asserted-by":"crossref","unstructured":"Wan M, Sun T, Vyas R, Zheng J, Granada E and Dubeau L . (1999). Oncogene, 18, 1545\u20131551.","DOI":"10.1038\/sj.onc.1202476"},{"key":"BF1206474_CR36","doi-asserted-by":"crossref","unstructured":"Wooster R, Bignell G, Lancaster J, Swift S, Seal S, Mangion J, Collins N, Gregory S, Gumbs C, Micklem G, Barfoot R, Hamoudi R, Patel S, Rice C, Biggs P, Hashim Y, Smith A, Connor F, Arason A, Gudmundsson J, Ficence D, Kelsell D, Ford D, Tonin P, Bishop DT, Spurr NK, Ponder BAJ, Eeles R, Peto J, Devilee P, Cornelisse C, Lynch H, Narod S, Lenoir G, Egilsson V, Barkadottir RB, Easton BF, Bentley DR, Futreal PA, Ashworth A and Stratton M . (1995). Nature, 378, 789\u2013792.","DOI":"10.1038\/378789a0"},{"key":"BF1206474_CR37","doi-asserted-by":"crossref","unstructured":"Wurster-Hill DH, Cannizzaro LA, Pettengill OS, Sorenson GD, Gate CC and Maurer LH . (1984). Cancer Genet. Cytogenet., 13, 303\u2013330.","DOI":"10.1016\/0165-4608(84)90075-X"},{"key":"BF1206474_CR38","doi-asserted-by":"crossref","unstructured":"Yoo HW, Warner CA, Chen CH, and Desnick RJ . (1993). Genomics, 15, 21\u201329.","DOI":"10.1006\/geno.1993.1005"},{"key":"BF1206474_CR39","doi-asserted-by":"crossref","unstructured":"Zhang Y, Matthiesen P, Siebert R, Harder S, Theile M, Scherneck S and Schlegelberger B . (1998). Human Genet., 103, 727\u2013729.","DOI":"10.1007\/s004390050899"},{"key":"BF1206474_CR40","unstructured":"Zuppan P, Hall JM, Lee MK, Ponglikitmongkol M and King MC . (1991). Am. J. Hum. Genet., 48, 1065\u20131068."}],"container-title":["Oncogene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/1206474.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1206474","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1206474.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T22:45:36Z","timestamp":1647902736000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1206474"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,5,15]]},"references-count":40,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2003,5,15]]}},"alternative-id":["BF1206474"],"URL":"https:\/\/doi.org\/10.1038\/sj.onc.1206474","relation":{},"ISSN":["0950-9232","1476-5594"],"issn-type":[{"value":"0950-9232","type":"print"},{"value":"1476-5594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,5,15]]},"assertion":[{"value":"19 September 2002","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 February 2003","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 February 2003","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 May 2003","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}