{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T19:42:44Z","timestamp":1790970164016,"version":"4.1.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"14","license":[{"start":{"date-parts":[[2005,2,14]],"date-time":"2005-02-14T00:00:00Z","timestamp":1108339200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2005,2,14]],"date-time":"2005-02-14T00:00:00Z","timestamp":1108339200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Oncogene"],"published-print":{"date-parts":[[2005,3,31]]},"DOI":"10.1038\/sj.onc.1208407","type":"journal-article","created":{"date-parts":[[2005,2,28]],"date-time":"2005-02-28T11:11:10Z","timestamp":1109589070000},"page":"2354-2366","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":129,"title":["Chronic gastritis in the hypochlorhydric gastrin-deficient mouse progresses to adenocarcinoma"],"prefix":"10.1038","volume":"24","author":[{"given":"Yana","family":"Zavros","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn A","family":"Eaton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiqun","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sivaprakash","family":"Rathinavelu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinay","family":"Katukuri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John Y","family":"Kao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda C","family":"Samuelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juanita L","family":"Merchant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2005,2,14]]},"reference":[{"key":"BF1208407_CR1","doi-asserted-by":"crossref","unstructured":"Bacchi CE and Gown AM . (1991). Lab. Invest., 64, 418\u2013424.","DOI":"10.1093\/forestry\/64.4.418"},{"key":"BF1208407_CR2","doi-asserted-by":"crossref","unstructured":"Bae SC and Choi JK . (2004). Oncogene, 23, 4336\u20134340.","DOI":"10.1038\/sj.onc.1207286"},{"key":"BF1208407_CR3","unstructured":"Barrett NR . (1957). Surgery, 41, 881\u2013894."},{"key":"BF1208407_CR4","doi-asserted-by":"crossref","unstructured":"Blaser MJ and Parsonnet J . (1994). J. Clin. Invest., 94, 4\u20138.","DOI":"10.1172\/JCI117336"},{"key":"BF1208407_CR5","doi-asserted-by":"crossref","unstructured":"Bowman T, Garcia R, Turkson J and Jove R . (2000). Oncogene, 19, 2474\u20132488.","DOI":"10.1038\/sj.onc.1203527"},{"key":"BF1208407_CR6","doi-asserted-by":"crossref","unstructured":"Bretscher A and Weber K . (1979). Proc. Natl. Acad. Sci. USA, 76, 2321\u20132325.","DOI":"10.1073\/pnas.76.5.2321"},{"key":"BF1208407_CR7","doi-asserted-by":"crossref","unstructured":"Bromberg JF, Wrzeszczynska MH, Devgan G, Zhao Y, Pestell RG, Albanese C and Darnell Jr JE . (1999). Cell, 98, 295\u2013303.","DOI":"10.1016\/S0092-8674(00)81959-5"},{"key":"BF1208407_CR8","unstructured":"Correa P . (1992). Cancer Res., 52, 6735\u20136740."},{"key":"BF1208407_CR9","unstructured":"Cover TL, Krishna US, Israel DA and Peek Jr RM . (2003). Cancer Res., 63, 951\u2013957."},{"key":"BF1208407_CR10","doi-asserted-by":"crossref","unstructured":"Darnell JEJ . (1997). Science, 277, 1630\u20131635.","DOI":"10.1126\/science.277.5332.1630"},{"key":"BF1208407_CR11","doi-asserted-by":"crossref","unstructured":"Eaton KA, Ringler SR and Danon SJ . (1999). Infect. Immun., 67, 4594\u20134602.","DOI":"10.1128\/IAI.67.9.4594-4602.1999"},{"key":"BF1208407_CR12","doi-asserted-by":"crossref","unstructured":"Fox JG, Dewhirst FE, Shen Z, Feng Y, Taylor NS, Paster BJ, Ericson RL, Lau CN, Correa P, Araya JC and Roa I . (1998). Gastroenterology, 114, 755\u2013763.","DOI":"10.1016\/S0016-5085(98)70589-X"},{"key":"BF1208407_CR13","unstructured":"Fox JG, Rogers AB, Ihrig M, Taylor NS, Whary MT, Dockray G, Varro A and Wang TC . (2003). Cancer Res., 63, 942\u2013950."},{"key":"BF1208407_CR14","doi-asserted-by":"crossref","unstructured":"Friis-Hansen L, Sundler F, Li Y, Gillespie PJ, Saunders TL, Greenson JK, Owyang C, Rehfeld JF and Samuelson LC . (1998). Am. J. Physiol., 274, G561\u2013G568.","DOI":"10.1152\/ajpgi.1998.274.3.G561"},{"key":"BF1208407_CR15","doi-asserted-by":"crossref","unstructured":"Harigai M, Hara M, Kawamoto M, Kawaguchi Y, Sugiura T, Tanaka M, Nakagawa M, Ichida H, Takagi K, Higami-Ohsako S, Shimada K and Kamatani N . (2004). Arthritis Rheum., 50, 2167\u20132177.","DOI":"10.1002\/art.20340"},{"key":"BF1208407_CR16","doi-asserted-by":"crossref","unstructured":"Johnson LR . (1977). Gastroenterology, 72, 788\u2013792.","DOI":"10.1016\/S0016-5085(77)80003-6"},{"key":"BF1208407_CR17","doi-asserted-by":"crossref","unstructured":"Judd LM, Alderman BM, Howlett M, Shulkes A, Dow C, Moverley J, Grail D, Jenkins BJ, Ernst M and Giraud AS . (2004). Gastroenterology, 126, 196\u2013207.","DOI":"10.1053\/j.gastro.2003.10.066"},{"key":"BF1208407_CR18","doi-asserted-by":"crossref","unstructured":"Kanda N, Seno H, Konda Y, Marusawa H, Kanai M, Nakajima T, Kawashima T, Nanakin A, Sawabu T, Uenoyama Y, Sekikawa A, Kawada M, Suzuki K, Kayahara T, Fukui H, Sawada M and Chiba T . (2004). Oncogene, 23, 4921\u20134929.","DOI":"10.1038\/sj.onc.1207606"},{"key":"BF1208407_CR19","doi-asserted-by":"crossref","unstructured":"Kang GH, Lee HJ, Hwang KS, Lee S, Kim JH and Kim JS . (2003). Am. J. Pathol., 163, 1551\u20131556.","DOI":"10.1016\/S0002-9440(10)63511-0"},{"key":"BF1208407_CR20","doi-asserted-by":"crossref","unstructured":"Kim TY, Lee HJ, Hwang KS, Lee M, Kim JW, Bang YJ and Kang GH . (2004). Lab. Invest., 84, 479\u2013484.","DOI":"10.1038\/labinvest.3700060"},{"key":"BF1208407_CR21","doi-asserted-by":"crossref","unstructured":"Koh TJ, Goldenring JR, Ito S, Mashimo I, Kopin AS, Varro A, Dockray GJ and Wang TC . (1997). Gastroenterology, 113, 1015\u20131025.","DOI":"10.1016\/S0016-5085(97)70199-9"},{"key":"BF1208407_CR22","doi-asserted-by":"crossref","unstructured":"Ku JL, Kang SB, Shin YK, Kang HC, Hong SH, Kim IJ, Shin JH, Han IO and Park JG . (2004). Oncogene, 23, 6736\u20136742.","DOI":"10.1038\/sj.onc.1207731"},{"key":"BF1208407_CR23","doi-asserted-by":"crossref","unstructured":"Kumble S, Omary MB, Fajardo LF and Triadafilopoulos G . (1996). Int. J. Cancer, 66, 48\u201354.","DOI":"10.1002\/(SICI)1097-0215(19960328)66:1<48::AID-IJC9>3.0.CO;2-Z"},{"key":"BF1208407_CR24","doi-asserted-by":"crossref","unstructured":"Lefebvre O, Chenard MP, Masson R, Linares J, Dierich A, LeMeur M, Wendling C, Tomasetto C, Chambon P and Rio MC . (1996). Science, 274, 259\u2013262.","DOI":"10.1126\/science.274.5285.259"},{"key":"BF1208407_CR25","doi-asserted-by":"crossref","unstructured":"Li QL, Ito K, Sakakura C, Fukamachi H, Inoue K, Chi XZ, Lee KY, Nomura S, Lee CW, Han SB, Kim HM, Kim WJ, Yamamoto H, Yamashita N, Yano T, Ikeda T, Itohara S, Inazawa J, Abe T, Hagiwara A, Yamagishi H, Ooe A, Kaneda A, Sugimura T, Ushijima T, Bae SC and Ito Y . (2002). Cell, 109, 113\u2013124.","DOI":"10.1016\/S0092-8674(02)00690-6"},{"key":"BF1208407_CR26","doi-asserted-by":"crossref","unstructured":"Moore JH, Lesser EJ, Erdody DH, Natale RB, Orringer MB and Beer DG . (1994). Int. J. Cancer, 56, 487\u2013493.","DOI":"10.1002\/ijc.2910560406"},{"key":"BF1208407_CR27","unstructured":"Mora LB, Buettner R, Seigne J, Diaz J, Ahmad N, Garcia R, Bowman T, Falcone R, Fairclough R, Cantor A, Muro-Cacho C, Livingston S, Karras J, Pow-Sang J and Jove R . (2002). Cancer Res., 62, 6659\u20136666."},{"key":"BF1208407_CR28","doi-asserted-by":"crossref","unstructured":"Nagata A, Ito M, Iwata N, Kuno J, Takano H, Minowa O, Chihara K, Matsui T and Noda T . (1996). Proc. Natl. Acad. Sci. USA, 93, 11825\u201311830.","DOI":"10.1073\/pnas.93.21.11825"},{"key":"BF1208407_CR29","doi-asserted-by":"crossref","unstructured":"Osborn M, Mazzoleni G, Santini D, Marrano D, Martinelli G and Weber K . (1988). Virchows Arch. A. Pathol. Anat. Histopathol., 413, 303\u2013312.","DOI":"10.1007\/BF00783022"},{"key":"BF1208407_CR30","doi-asserted-by":"crossref","unstructured":"Overbergh L, Valckx D, Waer M and Mathieu C . (1999). Cytokine, 11, 305\u2013312.","DOI":"10.1006\/cyto.1998.0426"},{"key":"BF1208407_CR31","doi-asserted-by":"crossref","unstructured":"Peek Jr RM . (2002). J. Gastroenterol., 37 (Suppl. 13), 10\u201316.","DOI":"10.1007\/BF02990093"},{"key":"BF1208407_CR32","doi-asserted-by":"crossref","unstructured":"Qing Y and Stark GR . (2004). J. Biol. Chem., 279, 41679\u201341685.","DOI":"10.1074\/jbc.M406413200"},{"key":"BF1208407_CR33","doi-asserted-by":"crossref","unstructured":"Semino-Mora C, Doi SQ, Marty A, Simko V, Carlstedt I and Dubois A . (2003). J. Infect. Dis., 187, 1165\u20131177.","DOI":"10.1086\/368133"},{"key":"BF1208407_CR34","doi-asserted-by":"crossref","unstructured":"Suter J, Hendry IR, Ndjountche L, Obholz K, Pru JK, Davis JS and Rueda BR . (2001). Biol. Reprod., 64, 1481\u20131486.","DOI":"10.1095\/biolreprod64.5.1481"},{"key":"BF1208407_CR35","doi-asserted-by":"crossref","unstructured":"Torquati A, O\u2019Rear L, Longobardi L, Spagnoli A, Richards WO and Daniel Beauchamp R . (2004). Surgery, 136, 310\u2013316.","DOI":"10.1016\/j.surg.2004.05.005"},{"key":"BF1208407_CR36","doi-asserted-by":"crossref","unstructured":"Waki T, Tamura G, Sato M, Terashima M, Nishizuka S and Motoyama T . (2003). Cancer Sci., 94, 360\u2013364.","DOI":"10.1111\/j.1349-7006.2003.tb01447.x"},{"key":"BF1208407_CR37","doi-asserted-by":"crossref","unstructured":"Wang TC, Dangler CA, Chen D, Goldenring JR, Koh T, Raychowdhury R, Coffey RJ, Ito S, Varro A, Dockray GJ and Fox JG . (2000). Gastroenterology, 118, 36\u201347.","DOI":"10.1016\/S0016-5085(00)70412-4"},{"key":"BF1208407_CR38","doi-asserted-by":"crossref","unstructured":"Wang TC, Koh TJ, Varro A, Cahill RJ, Dangler CA, Fox JG and Dockray GJ . (1996). J. Clin. Invest., 98, 1918\u20131929.","DOI":"10.1172\/JCI118993"},{"key":"BF1208407_CR39","doi-asserted-by":"crossref","unstructured":"Waterland RA and Jirtle RL . (2003). Mol. Cell. Biol., 23, 5293\u20135300.","DOI":"10.1128\/MCB.23.15.5293-5300.2003"},{"key":"BF1208407_CR40","doi-asserted-by":"crossref","unstructured":"Watson S, Durrant L and Morris D . (1989). Br. J. Cancer, 59, 554\u2013558.","DOI":"10.1038\/bjc.1989.112"},{"key":"BF1208407_CR41","doi-asserted-by":"crossref","unstructured":"Xu X, Brodie SG, Yang X, Im YH, Parks WT, Chen L, Zhou YX, Weinstein M, Kim SJ and Deng CX . (2000). Oncogene, 19, 1868\u20131874.","DOI":"10.1038\/sj.onc.1203504"},{"key":"BF1208407_CR42","doi-asserted-by":"crossref","unstructured":"Zavros Y, Rathinavelu S, Kao JY, Todisco A, Del Valle J, Weinstock JV, Low MJ and Merchant JL . (2003). Proc. Natl. Acad. Sci. USA, 100, 12944\u201312949.","DOI":"10.1073\/pnas.2135193100"},{"key":"BF1208407_CR43","doi-asserted-by":"crossref","unstructured":"Zavros Y, Rieder G, Ferguson A, Samuelson LC and Merchant JL . (2002a). Gastroenterology, 122, 119\u2013133.","DOI":"10.1053\/gast.2002.30298"},{"key":"BF1208407_CR44","doi-asserted-by":"crossref","unstructured":"Zavros Y, Rieder G, Ferguson A, Samuelson LC and Merchant JL . (2002b). Am. J. Physiol. Gastrointest. Liver Physiol., 282, G175\u2013G183.","DOI":"10.1152\/ajpgi.00287.2001"}],"container-title":["Oncogene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/1208407.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1208407","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1208407.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T08:24:15Z","timestamp":1647937455000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1208407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2,14]]},"references-count":44,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2005,3,31]]}},"alternative-id":["BF1208407"],"URL":"https:\/\/doi.org\/10.1038\/sj.onc.1208407","relation":{},"ISSN":["0950-9232","1476-5594"],"issn-type":[{"value":"0950-9232","type":"print"},{"value":"1476-5594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,2,14]]},"assertion":[{"value":"2 September 2004","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 November 2004","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 November 2004","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 February 2005","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}