{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,27]],"date-time":"2024-01-27T21:38:15Z","timestamp":1706391495441},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"47","license":[{"start":{"date-parts":[[2005,7,11]],"date-time":"2005-07-11T00:00:00Z","timestamp":1121040000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2005,7,11]],"date-time":"2005-07-11T00:00:00Z","timestamp":1121040000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Oncogene"],"published-print":{"date-parts":[[2005,10,27]]},"DOI":"10.1038\/sj.onc.1208887","type":"journal-article","created":{"date-parts":[[2005,7,12]],"date-time":"2005-07-12T18:51:04Z","timestamp":1121194264000},"page":"7120-7124","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A moderate reduction of Bcl-xL expression protects against tumorigenesis; however, it also increases susceptibility to tissue injury"],"prefix":"10.1038","volume":"24","author":[{"given":"Charles Christopher","family":"Henderson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongqiu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott Ryan","family":"Manson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob Joseph","family":"Riehm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaaki","family":"Kataoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melvin Wayne","family":"Flye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel Richard","family":"Garbow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"You","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven Jay","family":"Weintraub","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2005,7,11]]},"reference":[{"key":"BF1208887_CR1","unstructured":"Amundson SA, Myers TG, Scudiero D, Kitada S, Reed JC and Fornace Jr AJ . (2000). Cancer Res., 60, 6101\u20136110."},{"key":"BF1208887_CR2","doi-asserted-by":"crossref","unstructured":"Becker U, Deis A, Sorensen TI, Gronbaek M, Borch-Johnsen K, Muller CF, Schnohr P and Jensen G . (1996). Hepatology, 23, 1025\u20131029.","DOI":"10.1002\/hep.510230513"},{"key":"BF1208887_CR3","doi-asserted-by":"crossref","unstructured":"Bergsland EK . (2001). Semin. Oncol., 28, 521\u2013531.","DOI":"10.1053\/sonc.2001.26955"},{"key":"BF1208887_CR4","doi-asserted-by":"crossref","unstructured":"Boise LH, Gonzalez-Garcia M, Postema CE, Ding L, Lindsten T, Turka LA, Mao X, Nunez G and Thompson CB . (1993). Cell, 74, 597\u2013608.","DOI":"10.1016\/0092-8674(93)90508-N"},{"key":"BF1208887_CR5","doi-asserted-by":"crossref","unstructured":"Bradham CA, Plumpe J, Manns MP, Brenner DA and Trautwein C . (1998). Am. J. Physiol., 275, G387\u2013G392.","DOI":"10.1152\/ajpgi.1998.275.3.G387"},{"key":"BF1208887_CR6","doi-asserted-by":"crossref","unstructured":"Chen C, Edelstein LC and Gelinas C . (2000). Mol. Cell. Biol., 20, 2687\u20132695.","DOI":"10.1128\/MCB.20.8.2687-2695.2000"},{"key":"BF1208887_CR7","doi-asserted-by":"crossref","unstructured":"Chu ZL, McKinsey TA, Liu L, Gentry JJ, Malim MH and Ballard DW . (1997). Proc. Natl. Acad. Sci. USA, 94, 10057\u201310062.","DOI":"10.1073\/pnas.94.19.10057"},{"key":"BF1208887_CR8","doi-asserted-by":"crossref","unstructured":"Colantoni A, Idilman R, De Maria N, La Paglia N, Belmonte J, Wezeman F, Emanuele N, Van Thiel DH, Kovacs EJ and Emanuele MA . (2003). Alcohol Clin. Exp. Res., 27, 1184\u20131189.","DOI":"10.1097\/01.ALC.0000075834.52279.F9"},{"key":"BF1208887_CR9","unstructured":"Cossentino MJ and Wong RK . (2003). Semin. Gastrointest. Dis., 14, 128\u2013135."},{"key":"BF1208887_CR10","doi-asserted-by":"crossref","unstructured":"Day CP . (2001). J. Hepatol., 34, 330\u2013333.","DOI":"10.1016\/S0168-8278(00)00110-0"},{"key":"BF1208887_CR11","doi-asserted-by":"crossref","unstructured":"de la Coste A, Fabre M, McDonell N, Porteu A, Gilgenkrantz H, Perret C, Kahn A and Mignon A . (1999). Am. J. Physiol., 277, G702\u2013G708.","DOI":"10.1152\/ajpgi.1999.277.3.G702"},{"key":"BF1208887_CR12","doi-asserted-by":"crossref","unstructured":"Deverman BE, Cook BL, Manson SR, Niederhoff RA, Langer EM, Rosova I, Kulans LA, Fu X, Weinberg JS, Heinecke JW, Roth KA and Weintraub SJ . (2002). Cell, 111, 51\u201362.","DOI":"10.1016\/S0092-8674(02)00972-8"},{"key":"BF1208887_CR13","doi-asserted-by":"crossref","unstructured":"Diehl AM . (2000). Immunol. Rev., 174, 160\u2013171.","DOI":"10.1034\/j.1600-0528.2002.017411.x"},{"key":"BF1208887_CR14","doi-asserted-by":"crossref","unstructured":"Dvorakova K, Payne CM, Ramsey L, Holubec H, Sampliner R, Dominguez J, Dvorak B, Bernstein H, Bernstein C, Prasad A, Fass R, Cui H and Garewal H . (2004). Clin. Cancer Res., 10, 2020\u20132028.","DOI":"10.1158\/1078-0432.CCR-0437-03"},{"key":"BF1208887_CR15","doi-asserted-by":"crossref","unstructured":"Gonzalez-Amaro R, Garcia-Monzon C, Garcia-Buey L, Moreno-Otero R, Alonso JL, Yague E, Pivel JP, Lopez-Cabrera M, Fernandez-Ruiz E and Sanchez-Madrid F . (1994). J. Exp. Med., 179, 841\u2013848.","DOI":"10.1084\/jem.179.3.841"},{"key":"BF1208887_CR16","doi-asserted-by":"crossref","unstructured":"Green DR and Evan GI . (2002). Cancer Cell, 1, 19\u201330.","DOI":"10.1016\/S1535-6108(02)00024-7"},{"key":"BF1208887_CR17","doi-asserted-by":"crossref","unstructured":"Hanahan D and Weinberg RA . (2000). Cell, 100, 57\u201370.","DOI":"10.1016\/S0092-8674(00)81683-9"},{"key":"BF1208887_CR18","doi-asserted-by":"crossref","unstructured":"Hatano E and Brenner DA . (2001). Am. J. Physiol. Gastrointest. Liver Physiol., 281, G1357\u2013G1368.","DOI":"10.1152\/ajpgi.2001.281.6.G1357"},{"key":"BF1208887_CR19","doi-asserted-by":"crossref","unstructured":"Hong F, Kim WH, Tian Z, Jaruga B, Ishac E, Shen X and Gao B . (2002). Oncogene, 21, 32\u201343.","DOI":"10.1038\/sj.onc.1205016"},{"key":"BF1208887_CR20","doi-asserted-by":"crossref","unstructured":"Karnauskas R, Niu Q, Talapatra S, Plas DR, Greene ME, Crispino JD and Rudin CM . (2003). Oncogene, 22, 688\u2013698.","DOI":"10.1038\/sj.onc.1206159"},{"key":"BF1208887_CR21","doi-asserted-by":"crossref","unstructured":"Leist M, Gantner F, Bohlinger I, Germann PG, Tiegs G and Wendel A . (1994). J. Immunol., 153, 1778\u20131788.","DOI":"10.4049\/jimmunol.153.4.1778"},{"key":"BF1208887_CR22","doi-asserted-by":"crossref","unstructured":"Maclean KH, Keller UB, Rodriguez-Galindo C, Nilsson JA and Cleveland JL . (2003). Mol. Cell. Biol., 23, 7256\u20137270.","DOI":"10.1128\/MCB.23.20.7256-7270.2003"},{"key":"BF1208887_CR23","doi-asserted-by":"crossref","unstructured":"McManus DT, Olaru A and Meltzer SJ . (2004). Cancer Res., 64, 1561\u20131569.","DOI":"10.1158\/0008-5472.CAN-03-2438"},{"key":"BF1208887_CR24","doi-asserted-by":"crossref","unstructured":"Muto Y, Nouri-Aria KT, Meager A, Alexander GJ, Eddleston AL and Williams R . (1988). Lancet, 2, 72\u201374.","DOI":"10.1016\/S0140-6736(88)90006-2"},{"key":"BF1208887_CR25","doi-asserted-by":"crossref","unstructured":"Naik P, Karrim J and Hanahan D . (1996). Genes Dev., 10, 2105\u20132116.","DOI":"10.1101\/gad.10.17.2105"},{"key":"BF1208887_CR26","doi-asserted-by":"crossref","unstructured":"Natori S, Rust C, Stadheim LM, Srinivasan A, Burgart LJ and Gores GJ . (2001). J. Hepatol., 34, 248\u2013253.","DOI":"10.1016\/S0168-8278(00)00089-1"},{"key":"BF1208887_CR27","doi-asserted-by":"crossref","unstructured":"Ravi R, Bedi GC, Engstrom LW, Zeng Q, Mookerjee B, Gelinas C, Fuchs EJ and Bedi A . (2001). Nat. Cell Biol., 3, 409\u2013416.","DOI":"10.1038\/35070096"},{"key":"BF1208887_CR28","unstructured":"Riegman PH, Vissers KJ, Alers JC, Geelen E, Hop WC, Tilanus HW and van Dekken H . (2001). Cancer Res., 61, 3164\u20133170."},{"key":"BF1208887_CR29","doi-asserted-by":"crossref","unstructured":"Sato N, Lindros KO, Baraona E, Ikejima K, Mezey E, Jarvelainen HA and Ramchandani VA . (2001). Alcohol Clin. Exp. Res., 25, 40S\u201345S.","DOI":"10.1111\/j.1530-0277.2001.tb02371.x"},{"key":"BF1208887_CR30","doi-asserted-by":"crossref","unstructured":"Shimkin MB and Stoner GD . (1975). Adv. Cancer Res., 21, 1\u201358.","DOI":"10.1016\/S0065-230X(08)60970-7"},{"key":"BF1208887_CR31","doi-asserted-by":"crossref","unstructured":"Taylor JK, Zhang QQ, Wyatt JR and Dean NM . (1999). Nat. Biotechnol., 17, 1097\u20131100.","DOI":"10.1038\/15079"},{"key":"BF1208887_CR32","unstructured":"Tzung SP, Fausto N and Hockenbery DM . (1997). Am. J. Pathol., 150, 1985\u20131995."},{"key":"BF1208887_CR33","doi-asserted-by":"crossref","unstructured":"Van Antwerp DJ, Martin SJ, Verma IM and Green DR . (1998). Trends Cell Biol., 8, 107\u2013111.","DOI":"10.1016\/S0962-8924(97)01215-4"},{"key":"BF1208887_CR34","doi-asserted-by":"crossref","unstructured":"Wang CY, Guttridge DC, Mayo MW and Baldwin Jr AS . (1999). Mol. Cell. Biol., 19, 5923\u20135929.","DOI":"10.1128\/MCB.19.9.5923"},{"key":"BF1208887_CR35","doi-asserted-by":"crossref","unstructured":"Wang CY, Mayo MW, Korneluk RG, Goeddel DV and Baldwin Jr AS . (1998). Science, 281, 1680\u20131683.","DOI":"10.1126\/science.281.5383.1680"},{"key":"BF1208887_CR36","doi-asserted-by":"crossref","unstructured":"Wetscher GJ, Schwelberger H, Unger A, Offner FA, Profanter C, Glaser K, Klingler A, Gadenstaetter M and Klinger P . (1998). Am. J. Surg., 176, 569\u2013573.","DOI":"10.1016\/S0002-9610(98)00258-X"},{"key":"BF1208887_CR37","doi-asserted-by":"crossref","unstructured":"Yoon JH and Gores GJ . (2002). J. Hepatol., 37, 400\u2013410.","DOI":"10.1016\/S0168-8278(02)00209-X"},{"key":"BF1208887_CR38","doi-asserted-by":"crossref","unstructured":"Zhang H, Taylor J, Luther D, Johnston J, Murray S, Wyatt JR, Watt AT, Koo S, York-DeFalco C, Stecker K and Dean NM . (2003). J. Pharmacol. Exp. Ther., 307, 24\u201333.","DOI":"10.1124\/jpet.103.050435"},{"key":"BF1208887_CR39","doi-asserted-by":"crossref","unstructured":"Ziol M, Tepper M, Lohez M, Arcangeli G, Ganne N, Christidis C, Trinchet JC, Beaugrand M, Guillet JG and Guettier C . (2001). J. Hepatol., 34, 254\u2013260.","DOI":"10.1016\/S0168-8278(00)00047-7"},{"key":"BF1208887_CR40","doi-asserted-by":"crossref","unstructured":"Zong WX, Edelstein LC, Chen C, Bash J and Gelinas C . (1999). Genes Dev., 13, 382\u2013387.","DOI":"10.1101\/gad.13.4.382"}],"container-title":["Oncogene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/1208887.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1208887","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1208887.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,27]],"date-time":"2024-01-27T20:54:34Z","timestamp":1706388874000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1208887"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,7,11]]},"references-count":40,"journal-issue":{"issue":"47","published-print":{"date-parts":[[2005,10,27]]}},"alternative-id":["BF1208887"],"URL":"https:\/\/doi.org\/10.1038\/sj.onc.1208887","relation":{},"ISSN":["0950-9232","1476-5594"],"issn-type":[{"value":"0950-9232","type":"print"},{"value":"1476-5594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,7,11]]},"assertion":[{"value":"23 March 2005","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 May 2005","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 May 2005","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 July 2005","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}