{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T18:23:10Z","timestamp":1791397390183,"version":"4.3.3"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2007,7,23]],"date-time":"2007-07-23T00:00:00Z","timestamp":1185148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2007,7,23]],"date-time":"2007-07-23T00:00:00Z","timestamp":1185148800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Oncogene"],"published-print":{"date-parts":[[2008,1,17]]},"DOI":"10.1038\/sj.onc.1210668","type":"journal-article","created":{"date-parts":[[2007,7,24]],"date-time":"2007-07-24T15:04:25Z","timestamp":1185289465000},"page":"421-433","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":163,"title":["Two Epstein\u2013Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma"],"prefix":"10.1038","volume":"27","author":[{"given":"E","family":"Anderton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Yee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Crook","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R E","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M J","family":"Allday","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2007,7,23]]},"reference":[{"key":"BF1210668_CR1","doi-asserted-by":"publisher","first-page":"1382","DOI":"10.1002\/j.1460-2075.1995.tb07124.x","volume":"14","author":"MJ Allday","year":"1995","unstructured":"Allday MJ, Sinclair A, Parker G, Crawford DH, Farrell PJ . (1995). Epstein\u2013Barr virus efficiently immortalizes human B cells without neutralizing the function of p53. EMBO J 14: 1382\u20131391.","journal-title":"EMBO J"},{"key":"BF1210668_CR2","doi-asserted-by":"publisher","first-page":"4484","DOI":"10.1182\/blood-2004-07-2713","volume":"105","author":"AJ Alvi","year":"2005","unstructured":"Alvi AJ, Austen B, Weston VJ, Fegan C, MacCallum D, Gianella-Borradori A et al. (2005). A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival. Blood 105: 4484\u20134491.","journal-title":"Blood"},{"key":"BF1210668_CR3","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1128\/jvi.70.4.2481-2489.1996","volume":"70","author":"M Bain","year":"1996","unstructured":"Bain M, Watson RJ, Farrell PJ, Allday MJ . (1996). Epstein-Barr virus nuclear antigen 3C is a powerful repressor of transcription when tethered to DNA. J Virol 70: 2481\u20132489.","journal-title":"J Virol"},{"key":"BF1210668_CR4","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1098\/rstb.2000.0781","volume":"356","author":"GW Bornkamm","year":"2001","unstructured":"Bornkamm GW, Hammerschmidt W . (2001). Molecular virology of Epstein-Barr virus. Philos Trans R Soc Lond B Biol Sci 356: 437\u2013459.","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"BF1210668_CR5","doi-asserted-by":"publisher","first-page":"1735","DOI":"10.1126\/science.286.5445.1735","volume":"286","author":"P Bouillet","year":"1999","unstructured":"Bouillet P, Metcalf D, Huang DC, Tarlinton DM, Kay TW, Kontgen F et al. (1999). Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 286: 1735\u20131738.","journal-title":"Science"},{"issue":"Part 2","key":"BF1210668_CR6","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1099\/0022-1317-79-2-363","volume":"79","author":"PY Bourillot","year":"1998","unstructured":"Bourillot PY, Waltzer L, Sergeant A, Manet E . (1998). Transcriptional repression by the Epstein-Barr virus EBNA3A protein tethered to DNA does not require RBP-Jkappa. J Gen Virol 79 (Part 2): 363\u2013370.","journal-title":"J Gen Virol"},{"key":"BF1210668_CR7","doi-asserted-by":"publisher","first-page":"8060","DOI":"10.1073\/pnas.84.22.8060","volume":"84","author":"A Calender","year":"1987","unstructured":"Calender A, Billaud M, Aubry JP, Banchereau J, Vuillaume M, Lenoir GM . (1987). Epstein-Barr virus (EBV) induces expression of B-cell activation markers on in vitro infection of EBV-negative B-lymphoma cells. Proc Natl Acad Sci USA 84: 8060\u20138064.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF1210668_CR8","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/S1097-2765(02)00443-4","volume":"9","author":"G Chinnadurai","year":"2002","unstructured":"Chinnadurai G . (2002). CtBP, an unconventional transcriptional corepressor in development and oncogenesis. Mol Cell 9: 213\u2013224.","journal-title":"Mol Cell"},{"key":"BF1210668_CR9","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1128\/JVI.72.3.1862-1869.1998","volume":"72","author":"I Cludts","year":"1998","unstructured":"Cludts I, Farrell PJ . (1998). Multiple functions within the Epstein-Barr virus EBNA-3A protein. J Virol 72: 1862\u20131869.","journal-title":"J Virol"},{"key":"BF1210668_CR10","doi-asserted-by":"publisher","first-page":"2968","DOI":"10.4049\/jimmunol.175.5.2968","volume":"175","author":"C Clybouw","year":"2005","unstructured":"Clybouw C, McHichi B, Mouhamad S, Auffredou MT, Bourgeade MF, Sharma S et al. (2005). EBV infection of human B lymphocytes leads to down-regulation of Bim expression: relationship to resistance to apoptosis. J Immunol 175: 2968\u20132973.","journal-title":"J Immunol"},{"key":"BF1210668_CR11","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.ccr.2005.08.005","volume":"8","author":"CV Dang","year":"2005","unstructured":"Dang CV, O\u2019Donnell KA, Juopperi T . (2005). The great MYC escape in tumorigenesis. Cancer Cell 8: 177\u2013178.","journal-title":"Cancer Cell"},{"key":"BF1210668_CR12","doi-asserted-by":"publisher","first-page":"8245","DOI":"10.1073\/pnas.95.14.8245","volume":"95","author":"HJ Delecluse","year":"1998","unstructured":"Delecluse HJ, Hilsendegen T, Pich D, Zeidler R, Hammerschmidt W . (1998). Propagation and recovery of intact, infectious Epstein-Barr virus from prokaryotic to human cells. Proc Natl Acad Sci USA 95: 8245\u20138250.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF1210668_CR13","doi-asserted-by":"publisher","first-page":"6164","DOI":"10.1073\/pnas.0401471101","volume":"101","author":"A Egle","year":"2004","unstructured":"Egle A, Harris AW, Bouillet P, Cory S . (2004). Bim is a suppressor of Myc-induced mouse B cell leukemia. Proc Natl Acad Sci USA 101: 6164\u20136169.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF1210668_CR14","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1016\/j.molimm.2006.03.018","volume":"44","author":"M Epeldegui","year":"2007","unstructured":"Epeldegui M, Hung YP, McQuay A, Ambinder RF, Martinez-Maza O . (2007). Infection of human B cells with Epstein-Barr virus results in the expression of somatic hypermutation-inducing molecules and in the accrual of oncogene mutations. Mol Immunol 44: 934\u2013942.","journal-title":"Mol Immunol"},{"key":"BF1210668_CR15","doi-asserted-by":"publisher","first-page":"2317","DOI":"10.1038\/sj.onc.1208421","volume":"24","author":"A Essafi","year":"2005","unstructured":"Essafi A, Fernandez de Mattos S, Hassen YA, Soeiro I, Mufti GJ, Thomas NS et al. (2005). Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells. Oncogene 24: 2317\u20132329.","journal-title":"Oncogene"},{"key":"BF1210668_CR16","doi-asserted-by":"crossref","first-page":"3870","DOI":"10.1128\/jvi.61.12.3870-3878.1987","volume":"61","author":"J Finke","year":"1987","unstructured":"Finke J, Rowe M, Kallin B, Ernberg I, Rosen A, Dillner J et al. (1987). Monoclonal and polyclonal antibodies against Epstein-Barr virus nuclear antigen 5 (EBNA-5) detect multiple protein species in Burkitt's lymphoma and lymphoblastoid cell lines. J Virol 61: 3870\u20133878.","journal-title":"J Virol"},{"key":"BF1210668_CR17","doi-asserted-by":"crossref","first-page":"6216","DOI":"10.1128\/jvi.70.9.6216-6226.1996","volume":"70","author":"S Fruehling","year":"1996","unstructured":"Fruehling S, Lee SK, Herrold R, Frech B, Laux G, Kremmer E et al. (1996). Identification of latent membrane protein 2A (LMP2A) domains essential for the LMP2A dominant-negative effect on B-lymphocyte surface immunoglobulin signal transduction. J Virol 70: 6216\u20136226.","journal-title":"J Virol"},{"key":"BF1210668_CR18","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1038\/nature03845","volume":"436","author":"MT Hemann","year":"2005","unstructured":"Hemann MT, Bric A, Teruya-Feldstein J, Herbst A, Nilsson JA, Cordon-Cardo C et al. (2005). Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants. Nature 436: 807\u2013811.","journal-title":"Nature"},{"key":"BF1210668_CR19","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1016\/0092-8674(91)90007-L","volume":"65","author":"S Henderson","year":"1991","unstructured":"Henderson S, Rowe M, Gregory C, Croom-Carter D, Wang F, Longnecker R et al. (1991). Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death. Cell 65: 1107\u20131115.","journal-title":"Cell"},{"key":"BF1210668_CR20","doi-asserted-by":"publisher","first-page":"47197","DOI":"10.1074\/jbc.M208116200","volume":"277","author":"M Hickabottom","year":"2002","unstructured":"Hickabottom M, Parker GA, Freemont P, Crook T, Allday MJ . (2002). Two nonconsensus sites in the Epstein-Barr virus oncoprotein EBNA3A cooperate to bind the co-repressor carboxyl-terminal-binding protein (CtBP). J Biol Chem 277: 47197\u201347204.","journal-title":"J Biol Chem"},{"key":"BF1210668_CR21","doi-asserted-by":"publisher","first-page":"11200","DOI":"10.1128\/JVI.00897-06","volume":"80","author":"C Jimenez-Ramirez","year":"2006","unstructured":"Jimenez-Ramirez C, Brooks AJ, Forshell LP, Yakimchuk K, Zhao B, Fulgham TZ et al. (2006). Epstein-Barr virus EBNA-3C is targeted to and regulates expression from the bidirectional LMP-1\/2B promoter. J Virol 80: 11200\u201311208.","journal-title":"J Virol"},{"key":"BF1210668_CR22","doi-asserted-by":"crossref","first-page":"4481","DOI":"10.1128\/JVI.73.5.4481-4484.1999","volume":"73","author":"C Kaiser","year":"1999","unstructured":"Kaiser C, Laux G, Eick D, Jochner N, Bornkamm GW, Kempkes B . (1999). The proto-oncogene c-myc is a direct target gene of Epstein-Barr virus nuclear antigen 2. J Virol 73: 4481\u20134484.","journal-title":"J Virol"},{"key":"BF1210668_CR23","doi-asserted-by":"publisher","first-page":"14935","DOI":"10.1073\/pnas.0509988103","volume":"103","author":"GL Kelly","year":"2006","unstructured":"Kelly GL, Milner AE, Baldwin GS, Bell AI, Rickinson AB . (2006). Three restricted forms of Epstein-Barr virus latency counteracting apoptosis in c-myc-expressing Burkitt lymphoma cells. Proc Natl Acad Sci USA 103: 14935\u201314940.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF1210668_CR24","doi-asserted-by":"publisher","first-page":"10709","DOI":"10.1128\/JVI.79.16.10709-10717.2005","volume":"79","author":"GL Kelly","year":"2005","unstructured":"Kelly GL, Milner AE, Tierney RJ, Croom-Carter DS, Altmann M, Hammerschmidt W et al. (2005). Epstein-Barr virus nuclear antigen 2 (EBNA2) gene deletion is consistently linked with EBNA3A, -3B, and -3C expression in Burkitt's lymphoma cells and with increased resistance to apoptosis. J Virol 79: 10709\u201310717.","journal-title":"J Virol"},{"key":"BF1210668_CR25","doi-asserted-by":"publisher","first-page":"4261","DOI":"10.1128\/JVI.77.7.4261-4272.2003","volume":"77","author":"JS Knight","year":"2003","unstructured":"Knight JS, Lan K, Subramanian C, Robertson ES . (2003). Epstein-Barr virus nuclear antigen 3C recruits histone deacetylase activity and associates with the corepressors mSin3A and NCoR in human B-cell lines. J Virol 77: 4261\u20134272.","journal-title":"J Virol"},{"key":"BF1210668_CR26","doi-asserted-by":"crossref","first-page":"24157","DOI":"10.1016\/S0021-9258(18)35741-7","volume":"267","author":"CD Laherty","year":"1992","unstructured":"Laherty CD, Hu HM, Opipari AW, Wang F, Dixit VM . (1992). The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa B. J Biol Chem 267: 24157\u201324160.","journal-title":"J Biol Chem"},{"key":"BF1210668_CR27","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1128\/JVI.01096-06","volume":"81","author":"M Leao","year":"2007","unstructured":"Leao M, Anderton E, Wade M, Meekings K, Allday MJ . (2007). Epstein-Barr virus-induced resistance to drugs that activate the mitotic spindle assembly checkpoint in Burkitt's lymphoma cells. J Virol 81: 248\u2013260.","journal-title":"J Virol"},{"key":"BF1210668_CR28","doi-asserted-by":"publisher","first-page":"18811","DOI":"10.1074\/jbc.M301010200","volume":"278","author":"R Ley","year":"2003","unstructured":"Ley R, Balmanno K, Hadfield K, Weston C, Cook SJ . (2003). Activation of the ERK1\/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. J Biol Chem 278: 18811\u201318816.","journal-title":"J Biol Chem"},{"key":"BF1210668_CR29","doi-asserted-by":"publisher","first-page":"2171","DOI":"10.1038\/sj.onc.1204303","volume":"20","author":"MS Lindstrom","year":"2001","unstructured":"Lindstrom MS, Klangby U, Wiman KG . (2001). p14ARF homozygous deletion or MDM2 overexpression in Burkitt lymphoma lines carrying wild type p53. Oncogene 20: 2171\u20132177.","journal-title":"Oncogene"},{"key":"BF1210668_CR30","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1182\/blood-2006-06-026500","volume":"109","author":"C Mestre-Escorihuela","year":"2007","unstructured":"Mestre-Escorihuela C, Rubio-Moscardo F, Richter JA, Siebert R, Climent J, Fresquet V et al. (2007). Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas. Blood 109: 271\u2013280.","journal-title":"Blood"},{"key":"BF1210668_CR31","doi-asserted-by":"publisher","first-page":"7181","DOI":"10.1038\/sj.onc.1206838","volume":"22","author":"J O\u2019Nions","year":"2003","unstructured":"O\u2019Nions J, Allday MJ . (2003). Epstein-Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2. Oncogene 22: 7181\u20137191.","journal-title":"Oncogene"},{"key":"BF1210668_CR32","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/S0065-230X(04)92006-4","volume":"92","author":"J O\u2019Nions","year":"2004","unstructured":"O\u2019Nions J, Allday MJ . (2004). Deregulation of the cell cycle by the Epstein-Barr virus. Adv Cancer Res 92: 119\u2013186.","journal-title":"Adv Cancer Res"},{"key":"BF1210668_CR33","doi-asserted-by":"publisher","first-page":"12408","DOI":"10.1128\/JVI.01363-06","volume":"80","author":"J O\u2019Nions","year":"2006","unstructured":"O\u2019Nions J, Turner A, Craig R, Allday MJ . (2006). Epstein-Barr virus selectively deregulates DNA damage responses in normal B cells but has no detectable effect on regulation of the tumor suppressor p53. J Virol 80: 12408\u201312413.","journal-title":"J Virol"},{"key":"BF1210668_CR34","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1016\/S0002-9440(10)64557-9","volume":"157","author":"LA O\u2019Reilly","year":"2000","unstructured":"O\u2019Reilly LA, Cullen L, Visvader J, Lindeman GJ, Print C, Bath ML et al. (2000). The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells. Am J Pathol 157: 449\u2013461.","journal-title":"Am J Pathol"},{"key":"BF1210668_CR35","doi-asserted-by":"crossref","first-page":"5688","DOI":"10.1128\/JVI.73.7.5688-5697.1999","volume":"73","author":"SA Radkov","year":"1999","unstructured":"Radkov SA, Touitou R, Brehm A, Rowe M, West M, Kouzarides T et al. (1999). Epstein-Barr virus nuclear antigen 3C interacts with histone deacetylase to repress transcription. J Virol 73: 5688\u20135697.","journal-title":"J Virol"},{"key":"BF1210668_CR36","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1128\/JVI.78.1.367-377.2004","volume":"78","author":"A Rosendorff","year":"2004","unstructured":"Rosendorff A, Illanes D, David G, Lin J, Kieff E, Johannsen E . (2004). EBNA3C coactivation with EBNA2 requires a SUMO homology domain. J Virol 78: 367\u2013377.","journal-title":"J Virol"},{"key":"BF1210668_CR37","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1038\/nature01550","volume":"422","author":"Y Shi","year":"2003","unstructured":"Shi Y, Sawada J, Sui G, Affar el B, Whetstine JR, Lan F et al. (2003). Coordinated histone modifications mediated by a CtBP co-repressor complex. Nature 422: 735\u2013738.","journal-title":"Nature"},{"key":"BF1210668_CR38","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1038\/nri1568","volume":"5","author":"A Strasser","year":"2005","unstructured":"Strasser A . (2005). The role of BH3-only proteins in the immune system. Nat Rev Immunol 5: 189\u2013200.","journal-title":"Nat Rev Immunol"},{"key":"BF1210668_CR39","doi-asserted-by":"publisher","first-page":"1348","DOI":"10.1038\/sj.onc.1208300","volume":"24","author":"H Tagawa","year":"2005","unstructured":"Tagawa H, Karnan S, Suzuki R, Matsuo K, Zhang X, Ota A et al. (2005). Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM. Oncogene 24: 1348\u20131358.","journal-title":"Oncogene"},{"key":"BF1210668_CR40","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/j.ccr.2005.02.008","volume":"7","author":"TT Tan","year":"2005","unstructured":"Tan TT, Degenhardt K, Nelson DA, Beaudoin B, Nieves-Neira W, Bouillet P et al. (2005). Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy. Cancer Cell 7: 227\u2013238.","journal-title":"Cancer Cell"},{"key":"BF1210668_CR41","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1128\/jvi.67.4.2014-2025.1993","volume":"67","author":"B Tomkinson","year":"1993","unstructured":"Tomkinson B, Robertson E, Kieff E . (1993). Epstein-Barr virus nuclear proteins EBNA-3A and EBNA-3C are essential for B-lymphocyte growth transformation. J Virol 67: 2014\u20132025.","journal-title":"J Virol"},{"key":"BF1210668_CR42","doi-asserted-by":"publisher","first-page":"7749","DOI":"10.1128\/JVI.75.16.7749-7755.2001","volume":"75","author":"R Touitou","year":"2001","unstructured":"Touitou R, Hickabottom M, Parker G, Crook T, Allday MJ . (2001). Physical and functional interactions between the corepressor CtBP and the Epstein-Barr virus nuclear antigen EBNA3C. J Virol 75: 7749\u20137755.","journal-title":"J Virol"},{"key":"BF1210668_CR43","doi-asserted-by":"publisher","first-page":"1344","DOI":"10.1128\/MCB.20.4.1344-1360.2000","volume":"20","author":"M Wade","year":"2000","unstructured":"Wade M, Allday MJ . (2000). Epstein-Barr virus suppresses a G(2)\/M checkpoint activated by genotoxins. Mol Cell Biol 20: 1344\u20131360.","journal-title":"Mol Cell Biol"},{"key":"BF1210668_CR44","doi-asserted-by":"publisher","first-page":"3393","DOI":"10.1099\/vir.0.19387-0","volume":"84","author":"RE White","year":"2003","unstructured":"White RE, Calderwood MA, Whitehouse A . (2003). Generation and precise modification of a herpesvirus saimiri bacterial artificial chromosome demonstrates that the terminal repeats are required for both virus production and episomal persistence. J Gen Virol 84: 3393\u20133403.","journal-title":"J Gen Virol"},{"key":"BF1210668_CR45","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1038\/nrc1452","volume":"4","author":"LS Young","year":"2004","unstructured":"Young LS, Rickinson AB . (2004). Epstein-Barr virus: 40 years on. Nat Rev Cancer 4: 757\u2013768.","journal-title":"Nat Rev Cancer"},{"key":"BF1210668_CR46","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1006\/scbi.2001.0409","volume":"11","author":"U Zimber-Strobl","year":"2001","unstructured":"Zimber-Strobl U, Strobl LJ . (2001). EBNA2 and Notch signalling in Epstein-Barr virus mediated immortalization of B lymphocytes. Semin Cancer Biol 11: 423\u2013434.","journal-title":"Semin Cancer Biol"}],"container-title":["Oncogene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/1210668.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1210668","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1210668.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T09:30:52Z","timestamp":1647941452000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1210668"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7,23]]},"references-count":46,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,1,17]]}},"alternative-id":["BF1210668"],"URL":"https:\/\/doi.org\/10.1038\/sj.onc.1210668","relation":{},"ISSN":["0950-9232","1476-5594"],"issn-type":[{"value":"0950-9232","type":"print"},{"value":"1476-5594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,7,23]]},"assertion":[{"value":"16 March 2007","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 June 2007","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 June 2007","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 July 2007","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}