{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T12:13:04Z","timestamp":1779883984232,"version":"3.53.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2003,6,1]],"date-time":"2003-06-01T00:00:00Z","timestamp":1054425600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2003,6,1]],"date-time":"2003-06-01T00:00:00Z","timestamp":1054425600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Prostate Cancer Prostatic Dis"],"published-print":{"date-parts":[[2003,6,1]]},"DOI":"10.1038\/sj.pcan.4500646","type":"journal-article","created":{"date-parts":[[2003,6,12]],"date-time":"2003-06-12T15:14:53Z","timestamp":1055430893000},"page":"154-158","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["PSA testing in general practice"],"prefix":"10.1038","volume":"6","author":[{"given":"B","family":"Little","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K J","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Gormley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2003,6,12]]},"reference":[{"key":"BF4500646_CR1","unstructured":"URL: http:\/\/:nelh.nhs.uk\/psatesting\/."},{"key":"BF4500646_CR2","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1002\/ijc.1588","volume":"97","author":"HJ De Koning","year":"2002","unstructured":"De Koning HJ et al. Large scale randomised prostate cancer screening trials: programme performances in the European Randomised Screening for Prostate Cancer trial and the prostate, lung and ovary cancer trial. Int J Cancer 2002; 97: 237\u2013244.","journal-title":"Int J Cancer"},{"key":"BF4500646_CR3","doi-asserted-by":"publisher","first-page":"1322","DOI":"10.1016\/S0959-8049(00)00113-1","volume":"36","author":"W Horninger","year":"2000","unstructured":"Horninger W et al. Prostate cancer screening in the Tyrol, Austria: experience and results. Eur J Cancer 2000; 36: 1322\u20131335.","journal-title":"Eur J Cancer"},{"key":"BF4500646_CR4","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1002\/(SICI)1097-0045(19990301)38:4<296::AID-PROS5>3.0.CO;2-P","volume":"38","author":"ED Crawford","year":"1999","unstructured":"Crawford ED et al. Efficiency of prostate-specific antigen and digital rectal examination in screening, using 4.0\u2009ng\/ml and age-specific reference range as a cut-off for abnormal values. Prostate 1999; 38: 296\u2013302.","journal-title":"Prostate"},{"key":"BF4500646_CR5","unstructured":"URL: http:\/\/www.statistics.gov.uk\/census2001."},{"key":"BF4500646_CR6","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1002\/(SICI)1097-0045(19990201)38:2<83::AID-PROS1>3.0.CO;2-B","volume":"38","author":"F Labrie","year":"1999","unstructured":"Labrie F et al. Screening decreases prostate cancer death: first analysis of the 1988 Quebec prospective randomised controlled trial. Prostate 1999; 38: 83\u201391.","journal-title":"Prostate"},{"key":"BF4500646_CR7","first-page":"586","volume":"166","author":"L Perron","year":"2002","unstructured":"Perron L et al. PSA screening and prostate cancer mortality. Can Med J 2002; 166: 586\u2013591.","journal-title":"Can Med J"},{"key":"BF4500646_CR8","first-page":"178","volume":"110","author":"J Morris","year":"1997","unstructured":"Morris J, McNoe B, Adam H . Screening for prostate cancer: what do general practitioners think? N Z Med J 1997; 110: 178\u2013182.","journal-title":"N Z Med J"},{"key":"BF4500646_CR9","first-page":"70","volume":"160","author":"PS Bunting","year":"1999","unstructured":"Bunting PS, Goel V, Williams I, Iscoe NA . Prostate specific antigen testing in Ontario: reasons for testing patients without diagnosed prostate cancer. Can Med J 1999; 160: 70\u201375.","journal-title":"Can Med J"},{"key":"BF4500646_CR10","first-page":"169","volume":"49","author":"M McNaughton Collins","year":"2000","unstructured":"McNaughton Collins M, Stafford RS, Barry MJ . Age-specific patterns of prostate-specific antigen testing among primary care physician visits. J Fam Pract 2000; 49: 169\u2013172.","journal-title":"J Fam Pract"},{"key":"BF4500646_CR11","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1159\/000052427","volume":"39","author":"HJ Luboldt","year":"2001","unstructured":"Luboldt HJ et al. The Early Detection Project Group of the German Urological Association Early detection of prostate cancer in Germany: a study using digital rectal examination and 4.0\u2009ng\/ml prostate-specific antigen as cut-off. Eur Urol 2001; 39: 131\u2013137.","journal-title":"Eur Urol"},{"key":"BF4500646_CR12","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1080\/003655998750015124","volume":"32","author":"O Gustafsson","year":"1998","unstructured":"Gustafsson O et al. Prostate-specific antigen (PSA), PSA density and age-adjusted PSA reference values in screening for prostate cancer\u2014a study of a randomly selected population of 2,400 men. Scand J Urol Nephr 1998; 32: 373\u2013377.","journal-title":"Scand J Urol Nephr"},{"key":"BF4500646_CR13","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1016\/S0022-5347(17)38074-6","volume":"146","author":"MR Spitz","year":"1991","unstructured":"Spitz MR et al. Familial patterns of prostate cancer: a case\u2013control analysis. J Urol 1991; 146: 1305\u20131307.","journal-title":"J Urol"},{"key":"BF4500646_CR14","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1016\/S0022-5347(05)65852-1","volume":"166","author":"SL Yao","year":"2001","unstructured":"Yao SL, Lu-Yao G . Interval after prostate specific antigen testing and subsequent risk of incurable prostate cancer. J Urol 2001; 166: 861\u2013865.","journal-title":"J Urol"},{"key":"BF4500646_CR15","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/S0090-4295(99)00568-3","volume":"55","author":"K Ito","year":"2000","unstructured":"Ito K et al. Correlation of prostate-specific antigen before prostate cancer detection and clinicopathologic features: evaluation of mass screening populations. Urology 2000; 55: 705\u2013709.","journal-title":"Urology"},{"key":"BF4500646_CR16","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.1038\/sj.bjc.6690194","volume":"79","author":"L Maattanen","year":"1999","unstructured":"Maattanen L et al. European randomised study of prostate cancer screening: first-year results of the Finnish trial. Br J Cancer 1999; 79: 1210\u20131214.","journal-title":"Br J Cancer"},{"key":"BF4500646_CR17","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1111\/j.1464-410X.1994.tb16549.x","volume":"74","author":"RS Kirby","year":"1994","unstructured":"Kirby RS et al. Screening for carcinoma of the prostate: a GP based study. B J Urol 1994; 74: 64\u201371.","journal-title":"B J Urol"},{"key":"BF4500646_CR18","doi-asserted-by":"publisher","first-page":"1160","DOI":"10.1016\/S0022-5347(01)67538-4","volume":"153","author":"JE Oesterling","year":"1995","unstructured":"Oesterling JE, Jacobsen SJ, Cooner WH . The use of age specific reference ranges for serum prostate specific antigen in men 60 years old or older. J Urol 1995; 153: 1160\u20131163.","journal-title":"J Urol"},{"key":"BF4500646_CR19","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/S0022-5347(05)66084-3","volume":"166","author":"W Ellis","year":"2001","unstructured":"Ellis W et al. Serial prostate specific antigen, free to total prostate specific antigen ratio and complexed prostate specific antigen for the diagnosis of prostate cancer. J Urol 2001; 166: 93\u201399.","journal-title":"J Urol"},{"key":"BF4500646_CR20","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1093\/pubmed\/22.3.312","volume":"22","author":"HG Nijs","year":"2000","unstructured":"Nijs HG et al. Why do men refuse or attend population-based screening for prostate cancer. J Public Health Med 2000; 22: 312\u2013316.","journal-title":"J Public Health Med"}],"container-title":["Prostate Cancer and Prostatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/4500646.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/4500646","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/4500646.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T22:11:29Z","timestamp":1648678289000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/4500646"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,6,1]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2003,6,1]]}},"alternative-id":["BF4500646"],"URL":"https:\/\/doi.org\/10.1038\/sj.pcan.4500646","relation":{},"ISSN":["1365-7852","1476-5608"],"issn-type":[{"value":"1365-7852","type":"print"},{"value":"1476-5608","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,6,1]]},"assertion":[{"value":"12 August 2002","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 October 2002","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 November 2002","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 June 2003","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}