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This work was funded by Kyodo Milk Industry Co. Ltd and Human Metabolome Technologies, Inc. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. M. Matsumoto and E. Sawaki are employees of Kyodo Milk Industry Co. Ltd. and had a role in study design, data analysis, preparation of the manuscript and decision to publish the manuscript. T. Ooga is employee of Human Metabolome Technologies, Inc. and had a role in data analysis and decision to publish the manuscript. All of the other authors declare that they have no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"233"}}