{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T20:49:09Z","timestamp":1695156549949},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,10,23]],"date-time":"2014-10-23T00:00:00Z","timestamp":1414022400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"},{"start":{"date-parts":[[2014,10,23]],"date-time":"2014-10-23T00:00:00Z","timestamp":1414022400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/srep06737","type":"journal-article","created":{"date-parts":[[2014,10,23]],"date-time":"2014-10-23T09:12:34Z","timestamp":1414055554000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A Palindromic Motif in the \u22122084 to \u22122078 Upstream Region is Essential for ABCA12 Promoter Function in Cultured Human Keratinocytes"],"prefix":"10.1038","volume":"4","author":[{"given":"Yoshitaka","family":"Shimizu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Ogawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazumitsu","family":"Sugiura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun-ichi","family":"Takeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaori","family":"Sakai-Sawada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teruki","family":"Yanagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Kon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Sawamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masashi","family":"Akiyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,10,23]]},"reference":[{"key":"BFsrep06737_CR1","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1111\/j.1600-0625.2007.00614.x","volume":"16","author":"K Sakai","year":"2007","unstructured":"Sakai, K. et al. Localization of ABCA12 from Golgi apparatus to lamellar granules in human upper epidermal keratinocytes. Exp Dermatol 16, 920\u2013926, 10.1111\/j.1600-0625.2007.00614.x (2007).","journal-title":"Exp Dermatol"},{"key":"BFsrep06737_CR2","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1159\/000069811","volume":"98","author":"T Annilo","year":"2002","unstructured":"Annilo, T. et al. Identification and characterization of a novel ABCA subfamily member, ABCA12, located in the lamellar ichthyosis region on 2q34. Cytogenet Genome Res 98, 169\u2013176, 69811 (2002).","journal-title":"Cytogenet Genome Res"},{"key":"BFsrep06737_CR3","doi-asserted-by":"publisher","first-page":"1777","DOI":"10.1172\/JCI24834","volume":"115","author":"M Akiyama","year":"2005","unstructured":"Akiyama, M. et al. Mutations in lipid transporter ABCA12 in harlequin ichthyosis and functional recovery by corrective gene transfer. J Clin Invest 115, 1777\u20131784, 10.1172\/JCI24834 (2005).","journal-title":"J Clin Invest"},{"key":"BFsrep06737_CR4","doi-asserted-by":"publisher","first-page":"107","DOI":"10.4161\/derm.3.2.15136","volume":"3","author":"M Akiyama","year":"2011","unstructured":"Akiyama, M. The roles of ABCA12 in keratinocyte differentiation and lipid barrier formation in the epidermis. Dermatoendocrinol 3, 107\u2013112, 10.4161\/derm.3.2.15136 (2011).","journal-title":"Dermatoendocrinol"},{"key":"BFsrep06737_CR5","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1086\/429844","volume":"76","author":"DP Kelsell","year":"2005","unstructured":"Kelsell, D. P. et al. Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis. Am J Hum Genet 76, 794\u2013803, 10.1086\/429844 (2005).","journal-title":"Am J Hum Genet"},{"key":"BFsrep06737_CR6","doi-asserted-by":"publisher","first-page":"2369","DOI":"10.1093\/hmg\/ddg235","volume":"12","author":"C Lefevre","year":"2003","unstructured":"Lefevre, C. et al. Mutations in the transporter ABCA12 are associated with lamellar ichthyosis type 2. Hum Mol Genet 12, 2369\u20132378, 10.1093\/hmg\/ddg235 (2003).","journal-title":"Hum Mol Genet"},{"key":"BFsrep06737_CR7","doi-asserted-by":"publisher","first-page":"2669","DOI":"10.1038\/sj.jid.5700885","volume":"127","author":"K Natsuga","year":"2007","unstructured":"Natsuga, K. et al. Novel ABCA12 mutations identified in two cases of non-bullous congenital ichthyosiform erythroderma associated with multiple skin malignant neoplasia. J Invest Dermatol 127, 2669\u20132673, 10.1038\/sj.jid.5700885 (2007).","journal-title":"J Invest Dermatol"},{"key":"BFsrep06737_CR8","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1002\/humu.21326","volume":"31","author":"M Akiyama","year":"2010","unstructured":"Akiyama, M. ABCA12 mutations and autosomal recessive congenital ichthyosis: a review of genotype\/phenotype correlations and of pathogenetic concepts. Hum Mutat 31, 1090\u20131096, 10.1002\/humu.21326 (2010).","journal-title":"Hum Mutat"},{"key":"BFsrep06737_CR9","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.jdermsci.2012.11.004","volume":"69","author":"T Takeichi","year":"2013","unstructured":"Takeichi, T., Sugiura, K., Matsuda, K., Kono, M. & Akiyama, M. Novel ABCA12 splice site deletion mutation and ABCA12 mRNA analysis of pulled hair samples in harlequin ichthyosis. J Dermatol Sci 69, 259\u2013261, 10.1016\/j.jdermsci.2012.11.004 (2013).","journal-title":"J Dermatol Sci"},{"key":"BFsrep06737_CR10","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/0092-8674(80)90406-7","volume":"19","author":"H Hennings","year":"1980","unstructured":"Hennings, H. et al. Calcium regulation of growth and differentiation of mouse epidermal cells in culture. Cell 19, 245\u2013254 (1980).","journal-title":"Cell"},{"key":"BFsrep06737_CR11","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1111\/1523-1747.ep12273485","volume":"84","author":"GK Menon","year":"1985","unstructured":"Menon, G. K., Grayson, S. & Elias, P. M. Ionic calcium reservoirs in mammalian epidermis: ultrastructural localization by ion-capture cytochemistry. J Invest Dermatol 84, 508\u2013512 (1985).","journal-title":"J Invest Dermatol"},{"key":"BFsrep06737_CR12","doi-asserted-by":"publisher","first-page":"6131","DOI":"10.1073\/pnas.1318948111","volume":"111","author":"M Kellis","year":"2014","unstructured":"Kellis, M. et al. Defining functional DNA elements in the human genome. Proc Natl Acad Sci U S A 111, 6131\u20136138 (2014).","journal-title":"Proc Natl Acad Sci U S A"},{"key":"BFsrep06737_CR13","doi-asserted-by":"publisher","first-page":"D142","DOI":"10.1093\/nar\/gkt997","volume":"42","author":"A Mathelier","year":"2014","unstructured":"Mathelier, A. et al. JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles. Nucleic acids research 42, D142\u2013147, 10.1093\/nar\/gkt997 (2014).","journal-title":"Nucleic acids research"},{"key":"BFsrep06737_CR14","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1046\/j.1523-1747.1998.00071.x","volume":"110","author":"A Rossi","year":"1998","unstructured":"Rossi, A., Jang, S. I., Ceci, R., Steinert, P. M. & Markova, N. G. Effect of AP1 transcription factors on the regulation of transcription in normal human epidermal keratinocytes. J Invest Dermatol 110, 34\u201340, 10.1046\/j.1523-1747.1998.00071.x (1998).","journal-title":"J Invest Dermatol"},{"key":"BFsrep06737_CR15","doi-asserted-by":"publisher","first-page":"2223","DOI":"10.1093\/hmg\/6.13.2223","volume":"6","author":"K Yamada","year":"1997","unstructured":"Yamada, K. et al. Activation of the human transglutaminase 1 promoter in transgenic mice: terminal differentiation-specific expression of the TGM1-lacZ transgene in keratinized stratified squamous epithelia. Hum Mol Genet 6, 2223\u20132231 (1997).","journal-title":"Hum Mol Genet"},{"key":"BFsrep06737_CR16","doi-asserted-by":"crossref","unstructured":"International HapMap Consortium. A second generation human haplotype map of over 3.1 million SNPs. Nature 449, 851\u2013861 (2007).","DOI":"10.1038\/nature06258"},{"key":"BFsrep06737_CR17","doi-asserted-by":"publisher","first-page":"42268","DOI":"10.1074\/jbc.M205593200","volume":"277","author":"SI Jang","year":"2002","unstructured":"Jang, S. I. & Steinert, P. M. Loricrin expression in cultured human keratinocytes is controlled by a complex interplay between transcription factors of the Sp1, CREB, AP1 and AP2 families. J Biol Chem 277, 42268\u201342279, 10.1074\/jbc.M205593200 (2002).","journal-title":"J Biol Chem"},{"key":"BFsrep06737_CR18","doi-asserted-by":"publisher","first-page":"D764","DOI":"10.1093\/nar\/gkt1168","volume":"42","author":"D Karolchik","year":"2014","unstructured":"Karolchik, D. et al. The UCSC Genome Browser database: 2014 update. Nucleic Acids Res 42, D764\u2013770, 10.1093\/nar\/gkt1168 (2014).","journal-title":"Nucleic Acids Res"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/srep06737.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/srep06737","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/srep06737.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T06:17:00Z","timestamp":1672985820000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/srep06737"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,23]]},"references-count":18,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2014,12,17]]}},"alternative-id":["BFsrep06737"],"URL":"https:\/\/doi.org\/10.1038\/srep06737","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,23]]},"assertion":[{"value":"10 June 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 October 2014","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 October 2014","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing financial interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"6737"}}