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We observed that plasma-initiated ultraviolet (UV) photolysis were responsible for the continues generation of OH<jats:sup>\u2022<\/jats:sup>\u2002species, that resulted in OH<jats:sup>\u2022<\/jats:sup>\u2002to be major reactive species (RS) in the solution. The density and lifetime of OH<jats:sup>\u2022<\/jats:sup>\u2002species acted inversely proportional to each other with increasing depth inside the solution. The cause of increased lifetime of OH<jats:sup>\u2022<\/jats:sup>\u2002inside the solution is predicted using theoretical and semiempirical calculations. Further, to predict the mechanism of conversion of hydroxide ion (OH<jats:sup>\u2212<\/jats:sup>) to OH<jats:sup>\u2022<\/jats:sup>\u2002or H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub> (hydrogen peroxide) and electron, we determined the current inside the solution of different pH. Additionally, we have investigated the critical criterion for OH<jats:sup>\u2022<\/jats:sup>\u2002interaction on cancer cell inducing apoptosis under effective OH<jats:sup>\u2022<\/jats:sup>\u2002exposure time. These studies are innovative in the field of plasma chemistry and medicine.<\/jats:p>","DOI":"10.1038\/srep09332","type":"journal-article","created":{"date-parts":[[2015,3,20]],"date-time":"2015-03-20T14:12:00Z","timestamp":1426860720000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":499,"title":["Generation mechanism of hydroxyl radical species and its lifetime prediction during the plasma-initiated ultraviolet (UV) photolysis"],"prefix":"10.1038","volume":"5","author":[{"given":"Pankaj","family":"Attri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Hee","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dae Hoon","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Hoon","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young J.","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han Sup","family":"Uhm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoung-Nam","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Fridman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Ha","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,3,20]]},"reference":[{"key":"BFsrep09332_CR1","doi-asserted-by":"publisher","first-page":"115020","DOI":"10.1088\/1367-2630\/11\/11\/115020","volume":"11","author":"D Dobrynin","year":"2009","unstructured":"Dobrynin, D. et al. 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