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To elucidate the underlying neuroplastic mechanisms of FD, the present study addressed the organization of finger movements during piano performance in pianists suffering from the condition. Principal component (PC) analysis identified three patterns of fundamental joint coordination constituting finger movements in both patients and controls. The first two coordination patterns described less individuated movements between the \u201cdystonic\u201d finger and key-striking fingers for patients compared to controls. The third coordination pattern, representing the individuation of movements between the middle and ring fingers, was evident during a sequence of strikes with these fingers in controls, which was absent in the patients. Consequently, rhythmic variability of keystrokes was more pronounced during this sequence of strikes for the patients. A stepwise multiple-regression analysis further identified greater variability of keystrokes for individuals displaying less individuated movements between the affected and striking fingers. The findings suggest that FD alters dexterous joint coordination so as to lower independent control of finger movements and thereby degrades fine motor control.<\/jats:p>","DOI":"10.1038\/srep13360","type":"journal-article","created":{"date-parts":[[2015,8,20]],"date-time":"2015-08-20T09:30:09Z","timestamp":1440063009000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Losing dexterity: patterns of impaired coordination of finger movements in musician\u2019s dystonia"],"prefix":"10.1038","volume":"5","author":[{"given":"Shinichi","family":"Furuya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenta","family":"Tominaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumio","family":"Miyazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eckart","family":"Altenm\u00fcller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,8,20]]},"reference":[{"key":"BFsrep13360_CR1","doi-asserted-by":"publisher","first-page":"13834","DOI":"10.1523\/JNEUROSCI.1170-14.2014","volume":"34","author":"S Furuya","year":"2014","unstructured":"Furuya, S., Klaus, M., Nitsche, M. 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