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From January 2006 to December 2010, the covered (experimental group) or bare stent (control group) was used in 131 and 127 patients, respectively. The recurrence rates of gastrointestinal bleeding (18.3% vs. 33.9%, <jats:italic>P<\/jats:italic>\u2009=\u20090.004) and refractory hydrothorax\/ascites (6.9% vs. 16.5%, <jats:italic>P<\/jats:italic>\u2009=\u20090.019) in the experimental group were significantly lower than those in the control group. The cumulative restenosis rates in 1, 2, 3, 4 and 5-years in the experimental group (6.9%, 11.5%, 19.1%, 26.0% and 35.9%, respectively) were significantly lower (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) than those in the control group (27.6%, 37.0%, 49.6%, 59.8%, 74.8%, respectively). Importantly, the 4 and 5-year survival rates in the experimental group (83.2% and 76.3%, respectively) were significantly higher (<jats:italic>P<\/jats:italic>\u2009=\u20090.001 and 0.02) than those in the control group (71.7% and 62.2%, respectively). The rate of secondary interventional therapy in the experimental group was significantly lower than that in the control group (20.6% vs. 49.6%; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Therefore, Fluency covered stent has advantages over the bare stent in terms of reducing the restenosis, recurrence and secondary interventional therapy, whereas improving the long-term survival for post-TIPS patients.<\/jats:p>","DOI":"10.1038\/srep21011","type":"journal-article","created":{"date-parts":[[2016,2,15]],"date-time":"2016-02-15T10:33:42Z","timestamp":1455532422000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Efficacy of covered and bare stent in TIPS for cirrhotic portal hypertension: A single-center randomized trial"],"prefix":"10.1038","volume":"6","author":[{"given":"Lei","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhibo","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhendong","family":"Yue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenhua","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengfei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuliang","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiannan","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiushi","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqun","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuquan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,2,15]]},"reference":[{"key":"BFsrep21011_CR1","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1148\/92.5.1112","volume":"92","author":"J Rosch","year":"1969","unstructured":"Rosch J., Hanafee W. 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