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To ascertain if phage encoded proteins could form the basis of a gonococcal vaccine, rabbits were orally infected with<jats:italic>S. enterica<\/jats:italic><jats:italic>Typhimurium<\/jats:italic>strain \u03c73987 harboring phagemid Ngo\u03a66\u2009fm. The elicited sera contained large quantities of anti-phage IgG and IgA antibodies that bound to the surface of<jats:italic>N. gonorrhoeae<\/jats:italic>cells, as shown by indirect fluorescent analysis and flow cytometry. The elicited sera was able to bind to several phage proteins. The sera also had bactericidal activity. 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