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Some reports indicated that LIPUS accelerated peripheral nerve regeneration including Schwann cells (SCs) and injured nerves. But little is known about its appropriate intensities on autograft nerves. This study was to investigate which intensity of LIPUS improved the regeneration of gold standard postsurgical nerves in experimental rat model. Sprague-Dawley rats were made into 10\u2009mm right side sciatic nerve reversed autologous nerve transplantation and randomly treated with 250\u2009mW\/cm<jats:sup>2<\/jats:sup>, 500\u2009mW\/cm<jats:sup>2<\/jats:sup> or 750\u2009mW\/cm<jats:sup>2<\/jats:sup> LIPUS for 2\u201312 weeks after operation. Functional and pathological results showed that LIPUS of 250\u2009mW\/cm<jats:sup>2<\/jats:sup> significantly induced faster rate of axonal regeneration. This suggested that autograft nerve regeneration was improved.<\/jats:p>","DOI":"10.1038\/srep22773","type":"journal-article","created":{"date-parts":[[2016,4,22]],"date-time":"2016-04-22T09:05:28Z","timestamp":1461315928000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":72,"title":["Low-intensity pulsed ultrasound treatment improved the rate of autograft peripheral nerve regeneration in rat"],"prefix":"10.1038","volume":"6","author":[{"given":"Wenli","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuexiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quanyi","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyuan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinxing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,4,22]]},"reference":[{"key":"BFsrep22773_CR1","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1055\/s-2007-1006407","volume":"13","author":"JK Terzis","year":"1997","unstructured":"Terzis, J. 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