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RDR1 also contributes to basal virus resistance. RDR1 has been studied in several species including <jats:italic>A. thaliana<\/jats:italic>, tobacco (<jats:italic>Nicotiana tabacum<\/jats:italic>), <jats:italic>N. benthamiana<\/jats:italic>, <jats:italic>N. attenuata<\/jats:italic> and tomato (<jats:italic>Solanum lycopersicum<\/jats:italic>) but not to our knowledge in potato (<jats:italic>S. tuberosum<\/jats:italic>). <jats:italic>StRDR1<\/jats:italic> was identified and shown to be salicylic acid-responsive. <jats:italic>StRDR1<\/jats:italic> transcript accumulation decreased in transgenic potato plants constitutively expressing a hairpin construct and these plants were challenged with three viruses: potato virus Y, potato virus X, and tobacco mosaic virus. Suppression of <jats:italic>StRDR1<\/jats:italic> gene expression did not increase the susceptibility of potato to these viruses. Phylogenetic analysis of <jats:italic>RDR<\/jats:italic> genes present in potato and in a range of other plant species identified a new <jats:italic>RDR<\/jats:italic> gene family, not present in potato and found only in Rosids (but apparently lost in the Rosid <jats:italic>A. thaliana<\/jats:italic>) for which we propose the name <jats:italic>RDR7<\/jats:italic>.<\/jats:p>","DOI":"10.1038\/srep23082","type":"journal-article","created":{"date-parts":[[2016,3,16]],"date-time":"2016-03-16T10:59:27Z","timestamp":1458125967000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["RNA-dependent RNA polymerase 1 in potato (Solanum tuberosum) and its relationship to other plant RNA-dependent RNA polymerases"],"prefix":"10.1038","volume":"6","author":[{"given":"Lydia J. 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