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We determined the clinical and molecular epidemiology of bacteremia caused by\n                    <jats:italic>Elizabethkingia-<\/jats:italic>\n                    like species from five regional hospitals in Hong Kong. Among 45 episodes of\n                    <jats:italic>Elizabethkingia<\/jats:italic>\n                    -like bacteremia, 21 were caused by\n                    <jats:italic>Elizabethkingia<\/jats:italic>\n                    , including 17\n                    <jats:italic>E. anophelis<\/jats:italic>\n                    , three\n                    <jats:italic>E. meningoseptica<\/jats:italic>\n                    and one\n                    <jats:italic>E. miricola<\/jats:italic>\n                    ; while 24 were caused by other diverse genera\/species, as determined by 16S rRNA gene sequencing. Of the 17 cases of\n                    <jats:italic>E. anophelis<\/jats:italic>\n                    bacteremia, 15 (88%) were clinically significant. The most common diagnosis was pneumonia (n\u2009=\u20095), followed by catheter-related bacteremia (n\u2009=\u20094), neonatal meningitis (n\u2009=\u20093), nosocomial bacteremia (n\u2009=\u20092) and neutropenic fever (n\u2009=\u20091).\n                    <jats:italic>E. anophelis<\/jats:italic>\n                    bacteremia was commonly associated with complications and carried 23.5% mortality. In contrast, of the 24 episodes of bacteremia due to non-\n                    <jats:italic>Elizabethkingia<\/jats:italic>\n                    species, 16 (67%) were clinically insignificant. Compared to non-\n                    <jats:italic>Elizabethkingia<\/jats:italic>\n                    bacteremia,\n                    <jats:italic>Elizabethkingia<\/jats:italic>\n                    bacteremia was associated with more clinically significant infections (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.01) and positive cultures from other sites (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.01), less polymicrobial bacteremia (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.01) and higher complication (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.05) and mortality (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.05) rates.\n                    <jats:italic>Elizabethkingia<\/jats:italic>\n                    bacteremia is predominantly caused by\n                    <jats:italic>E. anophelis<\/jats:italic>\n                    instead of\n                    <jats:italic>E. meningoseptica<\/jats:italic>\n                    .\n                    <jats:italic>Elizabethkingia<\/jats:italic>\n                    bacteremia, especially due to\n                    <jats:italic>E. anophelis<\/jats:italic>\n                    , carries significant morbidity and mortality and should be considered clinically significant unless proven otherwise.\n                  <\/jats:p>","DOI":"10.1038\/srep26045","type":"journal-article","created":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T05:28:27Z","timestamp":1463462907000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":187,"title":["Elizabethkingia anophelis bacteremia is associated with clinically significant infections and high mortality"],"prefix":"10.1038","volume":"6","author":[{"given":"Susanna K. 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