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Fifty patients with CSM who underwent 1- or 2-level ACCF with n-HA\/PA66 struts were retrospectively investigated. With a mean follow-up of 79.6 months, the overall mean JOA score, VAS and cervical alignment were improved significantly. At last follow-up, the fusion rate was 98% and the subsidence rate of the n-HA\/PA66 strut was 8%. The \u201cradiolucent gap\u201d at the interface between the n-HA\/PA66 strut and the vertebra was further noted to evaluate the osteoconductivity and osseointegration of the strut and the incidence of it was 62% at the last follow-up. Three patients suffered symptomatic adjacent segment degeneration (ASD). No significant difference was detected in the outcomes between 1- and 2-level corpectomy at follow-ups. In conclusion, the satisfactory outcomes in this study indicated that the n-HA\/PA66 strut was an effective graft for cervical reconstruction. Moreover, the osteoconductivity and osseointegration of the strut is still need to be optimized for future clinical application owing to the notably presence of \u201cradiolucent gap\u201d in present study.<\/jats:p>","DOI":"10.1038\/srep26751","type":"journal-article","created":{"date-parts":[[2016,5,26]],"date-time":"2016-05-26T09:31:39Z","timestamp":1464255099000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Long-term results of anterior cervical corpectomy and fusion with nano-hydroxyapatite\/polyamide 66 strut for cervical spondylotic myelopathy"],"prefix":"10.1038","volume":"6","author":[{"given":"Yuan","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianming","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoji","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zenghui","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiyang","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengxue","family":"Quan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,5,26]]},"reference":[{"key":"BFsrep26751_CR1","doi-asserted-by":"publisher","first-page":"607","DOI":"10.2106\/00004623-195840030-00009","volume":"40-A","author":"GW Smith","year":"1958","unstructured":"Smith, G. 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