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The participants\u2019 personal information, medical history, behavioral habits and clinical status were assessed by questionnaire, while the left ventricular dimensions, function and the presence and severity of VHD were evaluated by transthoracic echocardiography. This study analyzed the data of 3948 participants who were older than 60 years. Significant VHD was present in 1.93% of participants; the standardized prevalence of VHD among the elderly population in Hubei was 2.05% (95% CI: 1.61\u20132.49). The most frequent VHD was aortic regurgitation, followed by tricuspid regurgitation, mitral regurgitation and multiple valve diseases. Univariate analysis results indicated that compared with participants without VHD, those with VHD were older (p\u2009&lt;\u20090.001), with a higher body mass index (BMI) (p\u2009&lt;\u20090.001), were more likely to smoke (p\u2009=\u20090.04) and had higher rates of coronary artery disease (CAD) (p\u2009&lt;\u20090.001) and arrhythmia (p\u2009&lt;\u20090.001). The results of multinomial regression analysis of complex sampling indicated that combined mitral and aortic valve diseases were related to older age, male sex and smoking; CAD was associated with single left-sided VHD.<\/jats:p>","DOI":"10.1038\/srep27253","type":"journal-article","created":{"date-parts":[[2016,6,2]],"date-time":"2016-06-02T09:19:03Z","timestamp":1464859143000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Prevalence and correlates of valvular heart diseases in the elderly population in Hubei, China"],"prefix":"10.1038","volume":"6","author":[{"given":"Chang","family":"Shu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Si","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tingting","family":"Qin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tucheng","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingxing","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nianguo","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,6,2]]},"reference":[{"key":"BFsrep27253_CR1","doi-asserted-by":"publisher","first-page":"11","DOI":"10.5543\/tkda.2013.91112","volume":"41","author":"N Ozer","year":"2013","unstructured":"Ozer, N. 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