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Forty-six ocular globes of sheep (<jats:italic>Ovis aries<\/jats:italic>) were analyzed with a portable spectral-domain OCT device by two operators at different postmortem intervals (PMIs) as follows: <jats:italic>immediately<\/jats:italic> (i.e. within 10\u2009minutes), at the 30<jats:sup>th<\/jats:sup> minute, at the 1<jats:sup>st<\/jats:sup>, 6<jats:sup>th<\/jats:sup>, 12<jats:sup>th<\/jats:sup>, 24<jats:sup>th<\/jats:sup> and 48<jats:sup>th<\/jats:sup> hour and <jats:italic>later<\/jats:italic> (up to the 96<jats:sup>th<\/jats:sup> hour). The coefficient of repeatability ranged from 0.3% to 3.5% and coefficients of reproducibility ranged from 0.2% to 3.7% in the central region of the cornea. The intraclass correlation coefficients were particularly high at different PMIs, thus confirming good measurement reliability with the portable OCT. The average CCT decreased immediately and then increased thereafter, with two peaks at 6 and 24\u2009hours after death. Our results suggest that portable OCT is a reliable tool for monitoring CCT variations after death and may be useful in characterizing corneas before explantation, detecting quantitative variations during post-mortem corneal degeneration or assessing changes in CCT for forensic implications.<\/jats:p>","DOI":"10.1038\/srep30428","type":"journal-article","created":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T10:04:03Z","timestamp":1469527443000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Post-Mortem Corneal Thickness Measurements with a Portable Optical Coherence Tomography System: a Reliability Study"],"prefix":"10.1038","volume":"6","author":[{"given":"Pietro Emanuele","family":"Napoli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Nioi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernesto","family":"d\u2019Aloja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Fossarello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,7,26]]},"reference":[{"key":"BFsrep30428_CR1","doi-asserted-by":"publisher","first-page":"1205","DOI":"10.1109\/2944.796348","volume":"5","author":"JM Schmitt","year":"1999","unstructured":"Schmitt, J. 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