{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:33:21Z","timestamp":1790634801536,"version":"4.1.0"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T00:00:00Z","timestamp":1469491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T00:00:00Z","timestamp":1469491200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We evaluated the retinal function of retinal dragging (R<jats:sub>drag<\/jats:sub>) and radial retinal folds (R<jats:sub>folds<\/jats:sub>) in eyes with familial exudative vitreoretinopathy (FEVR) using full-field electroretinography (ERG). Seventeen eyes of nine patients with FEVR who had R<jats:sub>drag<\/jats:sub> or R<jats:sub>folds<\/jats:sub> were retrospectively studied. Eyes were classified into four groups according to the severity of the retinal alterations: Group 1, without R<jats:sub>drag<\/jats:sub> or R<jats:sub>folds<\/jats:sub> (5 eyes); Group 2, with R<jats:sub>drag<\/jats:sub> (4 eyes); Group 3, with R<jats:sub>folds<\/jats:sub> (6 eyes); and Group 4, with R<jats:sub>folds<\/jats:sub> in which all major retinal vessels were involved (2 eyes). The amplitudes of all ERG components and the implicit times of the photopic a- and b-waves and 30-Hz flicker responses were decreased or prolonged as the severity of the retinal alterations increased (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). The photopic negative response was most severely affected and nearly undetectable in all eyes in Groups 3 and 4, although the other ERG components were detectable in all eyes in Group 3 and one eye in Group 4. These results suggest the decrease of retinal functions was correlated with the degree of severity of R<jats:sub>drag<\/jats:sub> and R<jats:sub>folds<\/jats:sub> in eyes with FEVR. In addition, the function of the retinal ganglion cells appears to be more severely affected compared with the others.<\/jats:p>","DOI":"10.1038\/srep30523","type":"journal-article","created":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T09:09:53Z","timestamp":1469524193000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Electroretinographic effects of retinal dragging and retinal folds in eyes with familial exudative vitreoretinopathy"],"prefix":"10.1038","volume":"6","author":[{"given":"Yukari","family":"Yaguchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Katagiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoko","family":"Fukushima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadashi","family":"Yokoi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachiko","family":"Nishina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mineo","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriyuki","family":"Azuma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,7,26]]},"reference":[{"key":"BFsrep30523_CR1","first-page":"40","volume":"27","author":"M Nishimura","year":"1983","unstructured":"Nishimura, M. et al. 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